Abstract:
BACKGROUND:Our center has developed a multidisciplinary approach to percutaneous endovascular thrombolysis with the goal of improving outcomes in children with thrombosis. There is little data describing the safety and efficacy of endovascular thrombolysis and the frequency of post-thrombotic syndrome after thrombolysis in children. OBJECTIVE:Retrospective analysis of children undergoing percutaneous endovascular thrombolysis to determine (1) the safety and efficacy of this procedure and (2) the frequency of the diagnosis of post-thrombotic syndrome after thrombolysis. MATERIALS AND METHODS:We reviewed the medical and imaging databases for children who underwent percutaneous endovascular thrombolysis for deep venous thrombosis (DVT) between November 2008 and June 2013 at our institution. Demographic data were reviewed for the technical success and complications of thrombolysis and the last assigned post-thrombotic syndrome score using standardized scoring tools. RESULTS:Forty-one children ages 3 months to 21 years (median age: 15 years; 44% male) underwent percutaneous endovascular thrombolysis between November 2008 and June 2013. Upper extremity DVT occurred in 13 patients (32%); lower extremity DVT occurred in 28 patients (68%). All 41 patients received thrombolysis grading; 90% of those patients achieved greater than 50% thrombus lysis. Twenty-eight patients received formal post-thrombotic syndrome scoring and 4 (14%) met diagnostic criteria for post-thrombotic syndrome. One major bleeding episode and one pulmonary embolism occurred with no long-term sequelae. CONCLUSION:Endovascular thrombolysis for DVT in children is safe, effective at thrombus removal and may reduce the incidence of post-thrombotic syndrome. Randomized or larger clinical trials would be needed to determine the long-term benefits of endovascular thrombolysis.
journal_name
Pediatr Radioljournal_title
Pediatric radiologyauthors
Dandoy CE,Kukreja KU,Gruppo RA,Patel MN,Tarango Cdoi
10.1007/s00247-014-3209-4subject
Has Abstractpub_date
2015-04-01 00:00:00pages
719-26issue
5eissn
0301-0449issn
1432-1998journal_volume
45pub_type
杂志文章abstract::Among all causes of death in children from solid tumors, pediatric brain tumors are the most common. This article includes an overview of a subset of infratentorial and supratentorial tumors with a focus on tumor imaging features and molecular advances and treatments of these tumors. Key to understanding the imaging f...
journal_title:Pediatric radiology
pub_type: 杂志文章,评审
doi:10.1007/s00247-015-3326-8
更新日期:2015-09-01 00:00:00
abstract::An unusual case is presented of a vascular ring due to a right arch with mirror-image branching and a left ligamentum arteriosum from the descending aorta to the left pulmonary artery. There have been only four previous reports of this rare arch anomaly. In addition, the patient had no underlying congenital heart lesi...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02019065
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abstract::Isolated oesophageal leiomyomatosis in children is very rare. The association between leiomyomatosis of oesophagus and female genital tract and an Alport like hematuric nephritis has been recognized as a distinct entity by Garcia-Torres and Guarner. Since then few other cases of this syndrome have been observed. Conge...
journal_title:Pediatric radiology
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journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02467313
更新日期:1989-01-01 00:00:00
abstract::Gastrointestinal (GI) tract involvement in Langerhans cell histiocytosis is probably not uncommon [1,2], but reports of radiologic findings have been limited to the small intestine and mesenteric lymph nodes [3-5]. We report a 16-month-old child with known Langerhans cell histiocytosis, who was found to have mucosal i...
journal_title:Pediatric radiology
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abstract::Ferumoxytol is an ultra-small superparamagnetic iron oxide (USPIO) particle that is FDA-approved for parenteral treatment of iron deficiency anemia in adults with chronic kidney disease. Because of the association between gadolinium-based contrast agents and nephrogenic systemic fibrosis in patients with severe chroni...
journal_title:Pediatric radiology
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doi:10.1007/s00247-016-3605-z
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abstract::We report a case of perforation, fistula formation, and small bowel obstruction in a 2-year-old child who had ingested 32 small magnets. Multiple magnets will attract one another through the bowel wall and lead to pressure necrosis with complications. We recommend early surgical intervention before the onset of gastro...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-005-0056-3
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abstract:BACKGROUND:Recently a 320-detector-row CT (MDCT) scanner has become available that allows axial volumetric scanning of a 16-cm-long range (50 cm field of view) in a single 0.35-s rotation. For imaging neonates and small children, volume scanning is potentially of great advantage as the entire scan range can be acquired...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-009-1436-x
更新日期:2010-03-01 00:00:00
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journal_title:Pediatric radiology
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abstract::Suspected appendicitis is the most common indication for emergent abdominal surgery in children. The clinical diagnosis of appendicitis can be challenging, and CT is playing an increasing role in the evaluation of right lower quadrant pain. Occasionally, alternative diagnoses to appendicitis can be suggested on CT. Th...
journal_title:Pediatric radiology
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journal_title:Pediatric radiology
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doi:10.1007/s00247-015-3329-5
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journal_title:Pediatric radiology
pub_type: 杂志文章,评审
doi:10.1007/s00247-017-3910-1
更新日期:2017-10-01 00:00:00
abstract:BACKGROUND:Chronic lung disease (CLD) in premature infants shows a variable clinical course with different radiological manifestations. OBJECTIVE:To evaluate the correlation between parameters of trans-membrane permeability [albumin/secretory component (SC)] and oxidative stress [malondialdehyde (MDA)/SC] in tracheal ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s002470100444
更新日期:2001-05-01 00:00:00
abstract:BACKGROUND:Takayasu's arteritis (TA) is a chronic idiopathic inflammatory disease affecting primarily the aorta, its proximal branches and the pulmonary arteries. OBJECTIVES:To retrospectively review the angiograms of children with TA so as to describe the patterns of vascular involvement. PATIENTS AND METHODS:Twenty...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-002-0817-1
更新日期:2003-04-01 00:00:00
abstract::Rare earth filters are known to reduce radiation dose in radiological investigations. The present investigation used Er and Sm filters that were selected because of their chemical stability and ability to withstand prolonged exposure to the atmosphere. They were used in a comparison with a conventional aluminium filte...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF01601887
更新日期:1984-01-01 00:00:00
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journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF00973676
更新日期:1979-02-26 00:00:00
abstract::Hypertension due to transplant renal artery stenosis was treated with percutaneous transluminal angioplasty (PTA) in 6 children. 8 angioplasties were performed and the follow-up period varied between 3 and 66 months (average 23 months). The stenoses were located at the site of anastomosis in 4 children and distal to t...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02012999
更新日期:1992-01-01 00:00:00
abstract::We present an unusual case of popliteal entrapment syndrome type I in an 11-year-old boy. Presenting symptoms were exercise-related pain and pallor in his left lower leg. The diagnosis of popliteal entrapment syndrome was established by acral plethysmography, colour-coded Doppler sonography and MRI. After myotomy of t...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s002470050552
更新日期:1999-02-01 00:00:00
abstract::Intussusception in the pediatric patient may have a varied clinical presentation depending on its location, presence of lead point, intermittent occurrence, or underlying systemic disease. Computed tomography (CT) may be used at times in the evaluation of children with complicated presentations. The purpose of this in...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF01403699
更新日期:1996-01-01 00:00:00
abstract::Complete fracture-separation of humeral epiphyses, proximal or distal, represents unusual skeletal injuries in the battered infant. Radiographic identification of the type and extent of epiphyseal injury may be difficult due to lack of ossified epiphyseal centers. While arthrography can be a useful diagnostic and ther...
journal_title:Pediatric radiology
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journal_title:Pediatric radiology
pub_type: 临床试验,杂志文章
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journal_title:Pediatric radiology
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doi:10.1007/s00247-009-1519-8
更新日期:2010-07-01 00:00:00
abstract::Perigraft seroma is a rare complication of synthetic vascular grafts. We describe a new sign observed in two children who underwent computed tomography of the chest for further evaluation of seromas complicating modified Blalock-Taussig procedures in which a polytetrafluoroethylene graft was used. In both patients con...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s002470050141
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abstract::The results of MRI and MIBG scintigraphy performed on the spine of 14 children with neuroblastoma are reported. In 6 cases of diffuse spinal bone marrow tumor infiltration, diagnosis is easier with MIBG scintigraphy than with MRI. In 5 cases, MRI detected hyposignal of the vertebral body without any spinal abnormality...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02013507
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abstract::Peutz-Jeghers syndrome (PJS) is a rare, though well-described, hereditary polyposis syndrome associated with mucocutaneous pigmentation that typically presents in the second decade of life with complications related to intestinal polyps. We present two cases of teenaged girls presenting with small-bowel intussusceptio...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-002-0695-6
更新日期:2002-09-01 00:00:00
abstract:BACKGROUND:Aortic dilatation and dissection are rare but important complications of Turner syndrome that increase the risk of sudden death in young patients. OBJECTIVE:To assess the value of aortic MRI in patients with Turner syndrome; in particular to demonstrate early aortic dilatation. MATERIALS AND METHODS:A tota...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-004-1359-5
更新日期:2005-03-01 00:00:00
abstract::Most pediatric malignancies require some form of cross-sectional imaging, either for staging or response assessment. The majority of these are solid tumors and this review addresses the role of MRI, as well as other cross-sectional and functional imaging techniques, for evaluating the most common pediatric solid tumor...
journal_title:Pediatric radiology
pub_type: 杂志文章,评审
doi:10.1007/s00247-018-4162-4
更新日期:2018-08-01 00:00:00
abstract::Primary idiopathic chylopericardium is rare and represents a fraction of all pericardial effusions in the pediatric population. Most cases of chylopericardium occur as a complication of cardiac surgery or after trauma. They may also be caused by tuberculosis, neoplasm, or congenital lymphangiomatosis. Primary idiopath...
journal_title:Pediatric radiology
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更新日期:2003-05-01 00:00:00
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journal_title:Pediatric radiology
pub_type: 杂志文章
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更新日期:2008-05-01 00:00:00
abstract:BACKGROUND:White matter maturation is characterised by increasing fractional anisotropy (FA) and decreasing mean diffusivity (MD). Contradictory results have been published on the effect of premature birth on white matter maturation at term-equivalent age. OBJECTIVE:To assess the association of gestational age and low...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-012-2352-z
更新日期:2012-06-01 00:00:00