Value of MRI and MIBG-I123 scintigraphy in the diagnosis of spinal bone marrow involvement in neuroblastoma in children.

Abstract:

:The results of MRI and MIBG scintigraphy performed on the spine of 14 children with neuroblastoma are reported. In 6 cases of diffuse spinal bone marrow tumor infiltration, diagnosis is easier with MIBG scintigraphy than with MRI. In 5 cases, MRI detected hyposignal of the vertebral body without any spinal abnormality on MIBG scintigraphy. A discussion of the reasons for negative MIBG scintigraphy is presented and in these 5 cases, it is suggested that a lateral view of MIBG scintigraphy and HMDP-Tc99m scintigraphy may be performed, even vertebral body biopsy in order to assess bone marrow tumoral infiltration.

journal_name

Pediatr Radiol

journal_title

Pediatric radiology

authors

Bourliere Najean B,Siles S,Panuel M,Cammilleri S,Faure F,Devred P,Kaphan G

doi

10.1007/BF02013507

keywords:

subject

Has Abstract

pub_date

1992-01-01 00:00:00

pages

443-6

issue

6

eissn

0301-0449

issn

1432-1998

journal_volume

22

pub_type

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