Abstract:
BACKGROUND:Lymphatic malformations (LMs) are congenital lesions of the lymphatic system and consist of lymphatic channels and cystic spaces of varying sizes. Recent evidence has shown that LMs respond well to intralesional sclerotherapy. OBJECTIVE:The purpose of this retrospective study is to evaluate the outcome and efficacy of using doxycycline in treating macrocystic, microcystic and combined macro- and microcystic LMs in a tertiary-care pediatric center. MATERIALS AND METHODS:Fifty children (32 boys, 18 girls) underwent doxycycline sclerotherapy for treatment of LMs between January 2005 and October 2010. Demographics, imaging, doxycycline treatment details, complications and follow-up details were documented. RESULTS:The mean age at first treatment was 5.9 years (3 days-17.8 years), median 4.2 years. Cervicofacial (19/50 children) and truncal (16/50 children) locations were the most frequently affected. One hundred forty-six sclerotherapy sessions were performed in 50 children (mean 2.9/child). The mean doxycycline dose/kg body weight for 146 sessions was 15.3 mg/kg (0.6-85.7 mg/kg). Complications occurred in 4/146 procedures. Clinical follow-up showed excellent response in 14/16 children with macrocystic LMs, 21/27 children with combined LMs and 4/7 children with microcystic LMs. CONCLUSION:Doxycycline is a safe and effective sclerosant agent for treating LMs in children, with a low complication rate.
journal_name
Pediatr Radioljournal_title
Pediatric radiologyauthors
Shergill A,John P,Amaral JGdoi
10.1007/s00247-012-2406-2subject
Has Abstractpub_date
2012-09-01 00:00:00pages
1080-8issue
9eissn
0301-0449issn
1432-1998journal_volume
42pub_type
临床试验,杂志文章abstract::A retrospective study was performed of the radiographic patterns of the lungs in children being followed in the Children's Hospital Aids Program (CHAP). The most consistent finding was a diffuse reticulonodular pattern in the lungs. In addition, lung consolidation, either isolated or in combination with nodules, was n...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02010931
更新日期:1993-01-01 00:00:00
abstract::Hemangiomas are common vascular tumors occurring in children. Though most of the lesions present in infants and young children with a typical appearance, it is important to understand that they all do not behave in the same way. Rather, they are a group of vascular lesions with different clinico-pathological subtypes,...
journal_title:Pediatric radiology
pub_type: 杂志文章,评审
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journal_title:Pediatric radiology
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doi:10.1007/BF01006901
更新日期:1975-06-13 00:00:00
abstract:BACKGROUND:CT optimization has a special importance in children. Smaller body size accentuates the importance of patient positioning affecting both radiation dose and image quality. OBJECTIVE:To determine the effect of vertical positioning on organ dose, image noise and contrast in pediatric chest CT examination. MAT...
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doi:10.1007/s00247-012-2611-z
更新日期:2013-06-01 00:00:00
abstract::Pericardial involvement in chronic granulomatous disease (CGD) is very rare. We present two children with known CGD and pericardial effusions in whom no microbial cause for the effusions was found. ...
journal_title:Pediatric radiology
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doi:10.1007/s002470050704
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abstract::The congenital subglottic hemangioma typically appears as an asymmetric subglottic narrowing or mass on frontal neck radiographs. Therefore, soft tissue neck radiography has been advocated as a definitive non-operative approach for diagnosing these lesions. However, we have noted similar asymmetric subglottic narrowin...
journal_title:Pediatric radiology
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doi:10.1007/BF02388997
更新日期:1988-01-01 00:00:00
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journal_title:Pediatric radiology
pub_type: 杂志文章,评审
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更新日期:2011-09-01 00:00:00
abstract:BACKGROUND:High-signal T2-weighted bone marrow changes can be found in both bone marrow edema and hematopoietic marrow and are often seen on pediatric MR images of the feet and ankle. OBJECTIVE:To evaluate whether high-signal T2 changes of the bone marrow seen on pediatric MRI of feet and ankles represent residual hem...
journal_title:Pediatric radiology
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更新日期:2006-07-01 00:00:00
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journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s002470050064
更新日期:1997-01-01 00:00:00
abstract::Systemic hypertension after renal transplantation in children is frequent, occurring in 85% of the cases and may be the cause of severe neurologic complications. This can be due to multiple factors such as: rejection, recurrence of initial disease, steroid, etc. ... Among those factors, renal transplant artery stenosi...
journal_title:Pediatric radiology
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更新日期:1989-01-01 00:00:00
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更新日期:2004-07-01 00:00:00
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更新日期:2020-06-01 00:00:00
abstract:BACKGROUND:Aortic dilatation and dissection are rare but important complications of Turner syndrome that increase the risk of sudden death in young patients. OBJECTIVE:To assess the value of aortic MRI in patients with Turner syndrome; in particular to demonstrate early aortic dilatation. MATERIALS AND METHODS:A tota...
journal_title:Pediatric radiology
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更新日期:2005-03-01 00:00:00
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journal_title:Pediatric radiology
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更新日期:2011-05-01 00:00:00
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journal_title:Pediatric radiology
pub_type: 杂志文章
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更新日期:1985-01-01 00:00:00
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abstract:BACKGROUND:Crohn disease is a chronic inflammatory condition that can lead to intestinal strictures. The presence of fibrosis within strictures alters optimal management but is not reliably detected by current imaging methods. OBJECTIVE:To correlate the MRI features of surgically resected small-bowel strictures in ped...
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更新日期:2016-04-01 00:00:00
abstract:BACKGROUND:Fluoroscopy is an important tool for diagnosis in the pediatric population, but it carries the risk of radiation exposure. Because radiology resident education and experience in the use of fluoroscopy equipment in children vary, we implemented an intervention to standardize fluoroscopy training. OBJECTIVE:T...
journal_title:Pediatric radiology
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更新日期:2015-02-01 00:00:00
abstract:BACKGROUND:Primary placement of percutaneous radiologic button gastrostomy has been successfully performed in adults but research is lacking as to its success in children during cancer treatment. OBJECTIVE:To assess the safety and effectiveness of such treatment at a single center. MATERIALS AND METHODS:We conducted ...
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journal_title:Pediatric radiology
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abstract:BACKGROUND:Endoscopic ultrasound is seldom available at paediatric centres; therefore drainage of pancreatic pseudocysts in children has traditionally been achieved by surgery. OBJECTIVE:This study assessed the feasibility and safety of performing image-guided internal drainage of pancreatic pseudocysts with a flanged...
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pub_type: 杂志文章,多中心研究
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abstract::Periventricular leukomalacia (PVL) is a common finding during neurosonography of preterm infants. Secondary thinning of the corpus callosum is seen following PVL, typically from loss of hemispheric white matter tracts. We report a case of direct involvement of the corpus callosum with PVL, its pathogenesis, and its po...
journal_title:Pediatric radiology
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更新日期:1997-07-01 00:00:00
abstract::Ectopic thyroid gland is a well-known developmental anomaly. We present a child with a unique anatomical variant of this anomaly, namely double ectopic thyroid. The purpose of this report is to demonstrate the scintigraphic findings and to emphasize the importance of performing a thyroid scan in every case of thyroid ...
journal_title:Pediatric radiology
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journal_title:Pediatric radiology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
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更新日期:2011-11-01 00:00:00
abstract::A case of pyelocalyceal diverticula in a patient with the Beckwith-Wiedemann syndrome is presented. The abnormalities were first identified on screening ultrasound and confirmed at excretory urography. The diverticula in this syndrome are likely secondary to hereditary embryopathy of the kidneys. ...
journal_title:Pediatric radiology
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doi:10.1007/BF02386605
更新日期:1987-01-01 00:00:00
abstract::Inflammatory bowel diseases (IBDs), including Crohn disease (CD) and ulcerative colitis (UC), often affect children and adolescents. Their diagnosis is based on the integration of clinical, biological, endoscopic, histological and radiological data. The paediatric radiologist may help the clinician in many ways. In ch...
journal_title:Pediatric radiology
pub_type: 杂志文章,评审
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更新日期:2007-11-01 00:00:00
abstract:BACKGROUND:Optic pathway gliomas (OPGs) are common pediatric brain tumors that pose significant clinical challenges with regard to predicting which tumors are likely to become symptomatic and require treatment. These tumors can arise sporadically or in the context of the inherited cancer predisposition syndrome neurofi...
journal_title:Pediatric radiology
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更新日期:2008-12-01 00:00:00
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journal_title:Pediatric radiology
pub_type: 杂志文章
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