Abstract:
:Although the future often seems intangible, we can make it more concrete by imagining prospective events. Here, using functional MRI, we demonstrate a mechanism by which the ventromedial prefrontal cortex supports such episodic simulations, and thereby contributes to affective foresight: This region supports processes that (i) integrate knowledge related to the elements that constitute an episode and (ii) represent the episode's emergent affective quality. The ventromedial prefrontal cortex achieves such integration via interactions with distributed cortical regions that process the individual elements. Its activation then signals the affective quality of the ensuing episode, which goes beyond the combined affective quality of its constituting elements. The integrative process further augments long-term retention of the episode, making it available at later time points. This mechanism thus renders the future tangible, providing a basis for farsighted behavior.
journal_name
Proc Natl Acad Sci U S Aauthors
Benoit RG,Szpunar KK,Schacter DLdoi
10.1073/pnas.1419274111subject
Has Abstractpub_date
2014-11-18 00:00:00pages
16550-5issue
46eissn
0027-8424issn
1091-6490pii
1419274111journal_volume
111pub_type
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