Abstract:
:Clostridium difficile is a Gram-positive, strictly anaerobic, spore-forming bacterium. It is the most common cause of antibiotic-associated diarrhea in hospitals and other healthcare facilities and is of significant concern because of the increasing morbidity and mortality rates as well as increased health care costs. Spectrum of presentation of Clostridium difficile infection ranges from mild, self-limiting diarrhea, to serious diarrhea, pseudomembranous colitis and life-threatening fulminant colitis, which may result in death. Prompt identification of patients with symptomatic Clostridium difficile infection is essential as the majority of patients respond quickly to antimicrobial therapy. Prevention is best accomplished by implementation of infection-control measures and by judicious use of antimicrobial agents.
journal_name
Asian Pac J Trop Medjournal_title
Asian Pacific journal of tropical medicineauthors
Khan FY,Elzouki ANdoi
10.1016/S1995-7645(14)60197-8subject
Has Abstractpub_date
2014-09-01 00:00:00pages
S6-S13eissn
1995-7645issn
2352-4146pii
S1995-7645(14)60197-8journal_volume
7S1pub_type
杂志文章abstract:OBJECTIVE:To study the correlation of lipid ratios and individual lipid indexes of patients with type 2 diabetes with glycosylated hemoglobin (HbA(1c)). METHODS:Samples were collected from 128 type 2 diabetic patients (aged 19-90 years; male 72, female 56). The sera were analyzed for HbA(1c), total cholesterol (TC), t...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/S1995-7645(12)60080-7
更新日期:2012-06-01 00:00:00
abstract::The 2014 Ebola outbreak in West Africa, primarily affecting Guinea, Sierra Leone, and Liberia, has exceeded all previous Ebola outbreaks in the number of cases and in international response. Although infections only occur frequently in Western Africa, the virus has the potential to spread globally and is classified as...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章,评审
doi:10.1016/j.apjtm.2015.09.001
更新日期:2015-10-01 00:00:00
abstract:OBJECTIVE:To determine resistance status of Culex species to different class of insecticides and assess the major anti-mosquito strategies employed by urban households and their possible effects on malaria acquisition. METHODS:Structured questionnaires were randomly administered to obtain information on demographic ch...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/S1995-7645(13)60153-4
更新日期:2013-11-01 00:00:00
abstract:OBJECTIVE:To investigate the effects of exogenous recombinant human brain natriuretic peptide (rhBNP) after primary percutaneous coronary intervention (PCI) on non-invasive hemodynamic in acute myocardial infarction patients with left ventricular failure. METHODS:A number of 96 acute myocardial infarction patients acc...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/j.apjtm.2016.06.006
更新日期:2016-08-01 00:00:00
abstract:OBJECTIVE:To determine antibiotic resistance patterns and virulence potential of Campylobacter jejuni (C. jejuni) isolates from clinical human diarrheal infections, cattle and healthy broilers. METHODS:Antibiotic sensitivity patterns of C. jejuni isolates were determined by Kirby Bauer Disc Diffusion assay. These isol...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/S1995-7645(14)60314-X
更新日期:2015-03-01 00:00:00
abstract:OBJECTIVE:To investigate the effect of pomegranate peel aqueous extract (PGE) on the development of secondary experimental echinococcosis and on the viability of Echinococcus granulosus protoscoleces, and the immunomodulatory properties of PGE. METHODS:Swiss mice were inoculated intraperitoneally with viable protoscol...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/j.apjtm.2016.01.038
更新日期:2016-03-01 00:00:00
abstract:OBJECTIVE:To investigate the hepatoprotective and antioxidant activities of Alchornea cordifolia (A. cordifolia) leaf extract. METHODS:Various solvent fractions of the methanol extract of the leaf of the plant A. cordifolia Mull. Arg (Fam: Euphorbiaceae) were evaluated for hepatoprotective activity by carbon tetrachlo...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/S1995-7645(12)60041-8
更新日期:2012-04-01 00:00:00
abstract:OBJECTIVE:To isolate and characterize antidiabetic component (bioactivity-guided fractionation) from hydro alcoholic extract of Ocimum sanctum (O. sanctum) aerial part. METHODS:Ten fractions (F1-F10) were isolated from hydro alcoholic extract of O. sanctum aerial part by column chromatography. All the fractions F1 to ...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/S1995-7645(11)60086-2
更新日期:2011-04-01 00:00:00
abstract:OBJECTIVE:To optimize the process parameters involved in the green synthesis of silver nanoparticles (G-SNPs) by aqueous extract of Rosa damascena petals and to evaluate the biocompatibility and anti cancer activity of the synthesized silver nanoparticles against human lung adenocarcinoma (A549). METHODS:The process v...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/S1995-7645(14)60249-2
更新日期:2014-09-01 00:00:00
abstract::A 19-year-old Asian Indian female presented with productive cough since the past one month and low grade fever since the past two weeks. She was diagnosed with pulmonary tuberculosis and treated with antitubercular drugs. Subsequently, delayed cultures of bronchoalveolar lavage fluid grew Burkholderia pseudomallei (B....
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/S1995-7645(14)60031-6
更新日期:2014-03-01 00:00:00
abstract:OBJECTIVE:To investigation the chemopreventive potential of Fumaria indica (F. indica) extract (FIE) on N-nitrosodiethylamine and CCl(4)-induced hepatocarcinogenesis in Wistar rats. METHODS:The experimental animals were divided into six groups (n=6). Hepatocellular carcinoma was induced by single intraperitoneal injec...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/S1995-7645(12)60128-X
更新日期:2012-08-01 00:00:00
abstract:OBJECTIVE:To evaluate parasite distribution and tissue tropism of Toxoplasma gondii tachyzoites in experimentally infected mice using real time QPCR. METHODS:In this survey 16 Balb/c mice were inoculated with 1 × 10(4) alive tachyzoites of Toxoplasma gondii RH strain. After 1, 2, 3 days post infection and the last day...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/S1995-7645(14)60087-0
更新日期:2014-07-01 00:00:00
abstract:OBJECTIVE:To screen for Escherichia coli (E. coli) resistant to tetracycline, followed by identification of tet efflux genes by polymerase chain reaction (PCR). In addition, detection of tetracycline residues in chicken livers and kidneys were conducted using high performance liquid chromatography-tandem quadrupole mas...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/S1995-7645(13)60125-X
更新日期:2013-09-01 00:00:00
abstract::Hookworm infection is a relatively common cause of anemia in endemic areas. The most common hookworm species are Ancylostoma duodenale and Necator americanus. In this report we present a case of overt gastrointestinal bleeding because of hookworm infection. Capsule endoscopy revealed many hookworms in the lumen of pro...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/S1995-7645(12)60051-0
更新日期:2012-04-01 00:00:00
abstract::Prevalence of dengue transmission has been alarmed by an estimate of 390 million infections per annum. Urban encroachment, ecological disruption and poor sanitation are all contributory factors of increased epidemiology. Complication however arises from the fact that dengue virus inherently exists as four different se...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章,评审
doi:10.1016/j.apjtm.2016.03.004
更新日期:2016-04-01 00:00:00
abstract:OBJECTIVE:To explore the role of miR-214 in the progression of hepatocellular carcinoma (HCC) and its inhibitory mechanisms in depressing the signaling pathway of β-catenin, this study was conducted. METHODS:We ectopically expressed miR-214 in HepG2 cells to obtain cell lines Lv-miR-214-HepG2 and their control Lv-cont...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/S1995-7645(14)60350-3
更新日期:2015-05-01 00:00:00
abstract:OBJECTIVE:To discuss the association between single nucleotide polymorphism (SNP) of rs3811047 in IL-1 F7 gene and rheumatoid arthritis (RA) susceptibility among the Han population in central plains of China. METHODS:A total of 276 RA patients admitted to our hospital from December 2009 to December 2011 together with ...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/S1995-7645(12)60204-1
更新日期:2013-01-01 00:00:00
abstract:OBJECTIVE:To investigate the biosorption potential of isolated bacteria as an alternative biosorbent material for the removal of zinc and nickel from aqueous solution in a bubble column bioreactor. METHORDS:In this study from four points of waste water treatment plant, some Gram-positive and Gram-negative bacteria und...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/S1995-7645(14)60231-5
更新日期:2014-09-01 00:00:00
abstract:OBJECTIVE:To investigate the relationship between genetic factor and prostate cancer (Pca) risk and the possible cause in it. METHODS:The polymorphisms of cytochrome P450 family 17 (CYPl7) rs743572, p27 V109G and androgen receptor (AR) gene CAG repeat length in peripheral blood from 70 cases and 70 controls were detec...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/j.apjtm.2015.06.005
更新日期:2015-07-01 00:00:00
abstract:OBJECTIVES:To build GPC3 gene short hairpin interference RNA (shRNA) slow virus vector, observe expression of Huh-7 GPC3 gene in human liver cell line proliferation apoptosis and the effect of GPC3 gene influencing on liver cancer cell growth, and provide theoretical basis for gene therapy of liver cancer. METHODS:Hep...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/S1995-7645(14)60136-X
更新日期:2014-10-01 00:00:00
abstract:OBJECTIVE:To investigate ultrastructural changes in pulmonary tissue of a rat model of pulmonary fibrosis following treatment with compound Carapax trionycis (C. trionycis; Biejia in Chinese) formula. METHODS:Sixty male Sprague-Dawley rats were randomly divided into four groups (n=15): compound C. trionycis formula hi...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/S1995-7645(13)60013-9
更新日期:2013-02-01 00:00:00
abstract:OBJECTIVE:To investigate the effect of ischemic precondition to protect ischemia-reperfusion injury and reduce IL-6 expression in the rats liver transplantation. METHODS:The rat portal vein infusion of autologous liver transplantation model were used. The rats were divided into ischemic preconditioning rats liver tran...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/S1995-7645(13)60045-0
更新日期:2013-05-13 00:00:00
abstract:OBJECTIVE:To screen, identify, and compare the serum biomarkers between anovulatory dysfunctional uterine bleeding (ADUB) and ovulatory dysfunctional uterine bleeding (ODUB) in Lizu females. METHODS:The subjects included 128 ADUB patients, 63 ODUB patients, and 93 controls. The serum and supernate of the subjects' men...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/S1995-7645(14)60012-2
更新日期:2014-02-01 00:00:00
abstract:OBJECTIVE:To evaluate the antihyperglycemic activity of leaves of Hyptis suaveolens using streptozotocin model. METHODS:Hyptis suaveolens extract (HSE) 250 and 500 mg/kg body weight was administered orally to streptozotocin induced diabetes, once daily for 21 days. RESULTS:A significant reduction in blood glucose was...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/S1995-7645(11)60175-2
更新日期:2011-09-01 00:00:00
abstract:OBJECTIVE:To identify the Leishmania species in infected sand flies by Real-time PCR coupled with HRM analysis. METHODS:Real-time PCR coupled with HRM analysis targeting the first internal transcribed spacer (ITS1) of nuclear ribosomal DNA as the genetic marker was used to identify and distinguish Leishmania species i...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/S1995-7645(14)60002-X
更新日期:2014-02-01 00:00:00
abstract:OBJECTIVE:To investigate the levels of serum cortisol in patients with uncomplicated Plasmodium falciparum (P. falciparum) malaria in an area of unstable malaria transmission in eastern Sudan. METHODS:The concentrations of cortisol were measured in sera of 25 patients with uncomplicated P. falciparum malaria (at prese...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/S1995-7645(11)60056-4
更新日期:2011-02-01 00:00:00
abstract:OBJECTIVE:To detect nematode eggs in sandpits in urban area in Vladivostok. METHODS:Totally 60 samples were collected from five districts. Sand samples were analysed using combined flotation-sedimentation method. In result, 18 sand samples were positive for at one or two parasites species. RESULTS:Overall, only 3 gen...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/j.apjtm.2016.11.002
更新日期:2016-12-01 00:00:00
abstract:OBJECTIVE:To immunize rabbits with 12 and 16 kDa recombinant subunits of antigen B from Echinococcus granulosus (E. granulosus) and measuring polyclonal antibody and humoral immune response using ELISA and gel diffusion. METHODS:Two mentioned antigens were cloned and expressed in expression vector and purified by affi...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/S1995-7645(12)60058-3
更新日期:2012-05-01 00:00:00
abstract:OBJECTIVE:To invest the differences among mesenchymal stem cells (MSCs) derived from different tissues and their impacts on clinical applications. METHODS:In this study, MSCs were isolated from adipose tissue (AD), umbilical cord tissue (UC), and menstrual blood (Men) and compared their biological characteristics in t...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/j.apjtm.2015.07.022
更新日期:2015-09-01 00:00:00
abstract:OBJECTIVE:To study the biocompatibility and neovascularization of the PLGA nanospheres wrapped with vascular endothelial growth factor (VEGF), which can improve bladder acellular matrix graft (BAMG) with local continuous release of VEGF. METHODS:A total of 18 rabbit model (length of stenosis: 3 cm) with anterior ureth...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/S1995-7645(13)60078-4
更新日期:2013-06-01 00:00:00