Abstract：
OBJECTIVE:To investigate the effect of ischemic precondition to protect ischemia-reperfusion injury and reduce IL-6 expression in the rats liver transplantation. METHODS:The rat portal vein infusion of autologous liver transplantation model were used. The rats were divided into ischemic preconditioning rats liver transplantation group (A group), the rats liver transplantation group (B group) and the normal rat control group (C group). Then we analyzed the changes of liver function, liver microstructure and the expression of IL-6, SOD and MDA within 48 h. RESULTS:The pathology of liver in group A showed lobular architecture essentially normal, the liver cells was slightly swell and no significant changes in postoperative 12 h. In transmission electron microscope (46 000×), the mitochondria of liver cells in group A became swelling, elliptical can cristae partially broken. But there still has a small amount of arrangement. While that in group, the mitochondria were swollen, became round, serious visible crest reduce or ruptured. The result of over function test showed that the serum ALT and AST levels in group A and B were both higher than that in group C at each time period, but the serum ALT and AST levels in group A were lower than that in group B. The expression changes of IL-6 in group B were higher than that in group A and B (P<0.05). The expression of MDA in group A is more obvious than that in group B (P<0.05) CONCLUSIONS:Ischemic precondition could alleviate part of ischemia-reperfusion injury in the rat liver transplantation, and also could reduce IL-6 expression to protect the liver cells against liver damage and inflammatory cytokine production.
journal_name
Asian Pac J Trop Medjournal_title
Asian Pacific journal of tropical medicineauthors
Cui LZ,Wang B,Chen LY,Zhou Jdoi
10.1016/S1995-7645(13)60045-0subject
Has Abstractpub_date
2013-05-13 00:00:00pages
395-9issue
5eissn
1995-7645issn
2352-4146pii
S1995-7645(13)60045-0journal_volume
6pub_type
杂志文章abstract：:Clostridium difficile is a Gram-positive, strictly anaerobic, spore-forming bacterium. It is the most common cause of antibiotic-associated diarrhea in hospitals and other healthcare facilities and is of significant concern because of the increasing morbidity and mortality rates as well as increased health care costs....
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/S1995-7645(14)60197-8
更新日期：2014-09-01 00:00:00
abstract：OBJECTIVE:To elucidates the immunoprophylactic potential of glutathion-s-transferase (GST) from cattle filarial parasite Setaria digitata (S. digitata) against lymphatic filariasis. METHODS:GST was purified through affinity chromatography (SdGST) and chacterized by SDS-PAGE and Nano-LC MS/MS analysis. Antibody isotype...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/S1995-7645(11)60066-7
更新日期：2011-03-01 00:00:00
abstract：OBJECTIVE:To investigate the pharmacological basis of its uses of Phyla nodiflora (P. nodiflora) for the treatment of anomalies predominantly by smooth muscle containing tissues such as gastrointestinal/vascular/broncho spasm and cardiovascular modulation. METHODS:The crude hydroalcoholic extract of P. nodiflora (Pn.C...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/j.apjtm.2017.10.021
更新日期：2017-12-01 00:00:00
abstract：OBJECTIVE:To determine the distribution of Duffy blood group genotypes in Balouch population as a major ethnic group that living in a sub-tropical area in south East of Iran. METHODS:In this study, the Duffy blood group FY phenotypes were determined using indirect anti-globulin technique and also genotype by PCR-RFLP ...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/S1995-7645(14)60021-3
更新日期：2014-03-01 00:00:00
abstract：OBJECTIVE:To invest the differences among mesenchymal stem cells (MSCs) derived from different tissues and their impacts on clinical applications. METHODS:In this study, MSCs were isolated from adipose tissue (AD), umbilical cord tissue (UC), and menstrual blood (Men) and compared their biological characteristics in t...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/j.apjtm.2015.07.022
更新日期：2015-09-01 00:00:00
abstract：OBJECTIVE:To examine the multiplication efficiency Japanese encephalitis virus (JEV) genotype I (GI) and genotype III (GIII) of different cell lines which originated from human, porcine, mosquitoes in order to prove mechanism of JEV GI replacement JEV GIII since it emerging in nature recent decades. METHODS:The mixtur...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/j.apjtm.2016.03.007
更新日期：2016-04-01 00:00:00
abstract：OBJECTIVE:To study the biocompatibility and neovascularization of the PLGA nanospheres wrapped with vascular endothelial growth factor (VEGF), which can improve bladder acellular matrix graft (BAMG) with local continuous release of VEGF. METHODS:A total of 18 rabbit model (length of stenosis: 3 cm) with anterior ureth...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/S1995-7645(13)60078-4
更新日期：2013-06-01 00:00:00
abstract：:Mycosis fungoides is a common cutaneous T-cell lymphoma, which is usually characterized by chronic, indolence progression, with absence of typical symptoms in early stage, metastasis to lymph nodes, bone marrow and visceral organs in later stage and ultimately progression to systemic lymphoma. It can result in seconda...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/S1995-7645(12)60138-2
更新日期：2012-08-01 00:00:00
abstract：OBJECTIVE:To assess the effect potency, and the immunomodulatory response of garlic oil extract in enhancing the host's immune system against the disorders caused by Schistosoma mansoni (S. mansoni) in mice at different stages of worm maturation. METHODS:A total of 70 male CD-1 Swiss albino mice were divided into 7 gr...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/j.apjtm.2015.11.016
更新日期：2015-12-01 00:00:00
abstract：OBJECTIVE:To determine the prevalence and intensity of infection and the risk factors associated with urinary schistosomiasis in pre-school and school aged children in Guma Local Government Area of Benue State, Nigeria. METHODS:Urine filtration technique using polycarbonate membrane filters was employed to process uri...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/S1995-7645(13)60188-1
更新日期：2014-01-01 00:00:00
abstract：OBJECTIVE:To investigate the correlation between E670G polymorphism of proprotein convertase subtilisin/kexin type 9 (PCSK9) gene and coronary heart disease (CHD), and contrastively study the regional differences of E670G polymorphism of PCSK9 gene between patients with CHD among the Han population in Hainan and three ...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/j.apjtm.2016.01.008
更新日期：2016-02-01 00:00:00
abstract：OBJECTIVE:To immunize rabbits with 12 and 16 kDa recombinant subunits of antigen B from Echinococcus granulosus (E. granulosus) and measuring polyclonal antibody and humoral immune response using ELISA and gel diffusion. METHODS:Two mentioned antigens were cloned and expressed in expression vector and purified by affi...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/S1995-7645(12)60058-3
更新日期：2012-05-01 00:00:00
abstract：:Brucellosis is a zoonotic disease characterized by reproductive failure in animals and undulent fever in humans. In cattle, it is caused by Brucella abortus while in goats by Brucella melitensis, the main cause of brucellosis in humans. Brucellosis in livestock has been associated with importation of animals from bree...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章,评审
doi：10.1016/j.apjtm.2016.11.007
更新日期：2016-12-01 00:00:00
abstract：OBJECTIVE:To investigate the effects of pectic polysaccharides extracted from Rauwolfia verticillata (Lour.) Baill.var.hainanensis Tsiang on an experimental murine colitis model. METHODS:Experimental colitis was induced by dextran sulfate sodium (DSS), and mice were divided into 4 groups: control, DSS alone, DSS plus ...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/S1995-7645(14)60306-0
更新日期：2015-02-01 00:00:00
abstract：OBJECTIVE:To investigate the therapeutic effect of the intervention treatment with different doses of Captopril on TNF-αcontents in serum of rheumatoid arthritis (RA) rats, and to provide the theoretical proofs for clinical application of Captopril in treatments of rheumatoid diseases. METHODS:Fifty Wistar rats were r...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/S1995-7645(14)60175-9
更新日期：2014-12-01 00:00:00
abstract：:Salmonella are most commonly associated with gastroenteritis and enteric fever in humans. Occasionally, dissemination of bacilli throughout the body results in establishment of localized foci of persistent infection especially in patients with debilitating diseases and immunosuppressive states. Infection at various ab...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/S1995-7645(11)60117-X
更新日期：2011-05-01 00:00:00
abstract：OBJECTIVE:To analyze anticancer activity of an ethyl acetate extract of endophytic fungi isolated from soursop leaf (Annona muricata L.). METHODS:Anticancer activity of fungal extracts was determined by observing its toxicity against MCF-7 (Michigan Cancer Foundation-7) cells in vitro by using the 3-(4,5-dimethylthiaz...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/j.apjtm.2017.06.004
更新日期：2017-06-01 00:00:00
abstract：OBJECTIVE:To clone the virB12 gene in pET28a expression vector for production of recombinant protein to be used as antigenic component for future serological test development. METHODS:Brucella melitensis (B. melitensis) 16M strain was cultured and bacterial DNA was extracted by Bioneer AccuPrep® Genomic DNA Extraction...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/S1995-7645(12)60089-3
更新日期：2012-07-01 00:00:00
abstract：OBJECTIVE:To explore the effect and mechanism of angiotensin II receptor blockers - Irbesartan on occurrence of ventricular arrhythmias in rats with myocardial ischemia. METHODS:Rats with embryonic cardiomyocytes-H9c2 were randomly divided into control group, ischemia group, Irbesartan group and Irbesartan + ischemia ...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/j.apjtm.2016.07.022
更新日期：2016-10-01 00:00:00
abstract：OBJECTIVE:To study the effect of levocarnitine (L-CN) on tissue inhibitor of metalloproteinase-1 (TIMP-1) and intercellular adhesion molecule-1 (ICAM-1) expression of rats with coronary heart disease and evaluate the protective effect of L-CN on myocardial cells. METHODS:High-fat diet feeding and intraperitoneal injec...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/j.apjtm.2016.01.025
更新日期：2016-03-01 00:00:00
abstract：OBJECTIVE:To evaluate the effect of hydroethanolic extract of yacon on the hyperglycemia induced by streptozotocin (STZ) in neonatal rats. METHODS:Wistar rats aged two days old received an intraperitoneal injection of STZ (160 mg/kg); after seven weeks, glycosuria was determined and animals with glucose levels above 2...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/j.apjtm.2016.03.033
更新日期：2016-05-01 00:00:00
abstract：OBJECTIVE:To study the involvement of variations in 4 genes associated with susceptibility and/or protection against HIV-1 in serodiscordant couples in Burkina Faso, namely, genes encoding HLA-B57, interferon regulatory factor 1 (IRF1), dendritic cell-specific ICAM3-grabbing nonintegrin (DC-SIGN) and CCR5 delta 32 (CCR...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/S1995-7645(14)60211-X
更新日期：2014-09-01 00:00:00
abstract：OBJECTIVE:To screen the antimicrobial potential of three ethnomedicinal plants Chassalia curviflora Thw. (C. curviflora), Cyclea peltata Hook. F. & Thomson (C. peltata) and Euphorbia hirta L (E. hirta) used in folk medicines in Aarukani hills Kani tribe, Tamil Nadu, India against human bacterial pathogens. METHODS:Ant...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/S1995-7645(11)60107-7
更新日期：2011-05-01 00:00:00
abstract：OBJECTIVE:To explore the relationship between IL-1β, IL-1Ra gene polymorphism and the occurrence of polycystic ovary syndrome (PCOS) infertility. METHODS:A total of 59 PCOS infertility cases visiting the reproductive center of our hospital from Mar. 2010 to Mar. 2012 and 56 healthy women were selected. ELISA method wa...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/S1995-7645(13)60030-9
更新日期：2013-03-01 00:00:00
abstract：OBJECTIVE:The present study deals with the investigation of larvicidal and ovicidal activities of benzene, hexane, ethyl acetate, methanol and chloroform leaf extract of Eclipta alba (E. alba) against dengue vector, Aedes aegypti (Ae. Aegypti). METHODS:Twenty five early III instar larvae of Ae. aegypti was exposed to ...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/S1995-7645(11)60026-6
更新日期：2011-01-01 00:00:00
abstract：OBJECTIVE:To describe the epidemiology of snake bite in the region and attempt to compare proven Russell's viper with hump-nosed viper bites. METHODS:All snake bite admissions to the Toxicology Unit of Teaching Hospital Peradeniya over three year from 2006 were included. RESULTS:Of the 776 snakebites, 665(86%) were u...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/S1995-7645(11)60147-8
更新日期：2011-07-01 00:00:00
abstract：OBJECTIVE:To confirm dengue infection among Russian tourists returned from Southeast and Mexico in 2010-2013 with clinical signs of infection. METHODS:Blood and serum samples from patients were collected. NS1 antigen and human IgM/IgG antibodies to dengue virus were identified using commercial tests manufactured by "S...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/S1995-7645(14)60194-2
更新日期：2015-02-01 00:00:00
abstract：OBJECTIVE:To optimize the process parameters involved in the green synthesis of silver nanoparticles (G-SNPs) by aqueous extract of Rosa damascena petals and to evaluate the biocompatibility and anti cancer activity of the synthesized silver nanoparticles against human lung adenocarcinoma (A549). METHODS:The process v...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/S1995-7645(14)60249-2
更新日期：2014-09-01 00:00:00
abstract：OBJECTIVE:To determine the contribution of total phenolic content (TPC) in glycation inhibitory activity of common tropical medicinal food and spices with potential antioxidative properties. METHODS:In vitro glucose-bovine serum albumin (BSA) assay was used. Ethanolic extracts of ten common household condiments/herbs ...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/S1995-7645(13)60097-8
更新日期：2013-07-01 00:00:00
abstract：OBJECTIVE:To screen for Escherichia coli (E. coli) resistant to tetracycline, followed by identification of tet efflux genes by polymerase chain reaction (PCR). In addition, detection of tetracycline residues in chicken livers and kidneys were conducted using high performance liquid chromatography-tandem quadrupole mas...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/S1995-7645(13)60125-X
更新日期：2013-09-01 00:00:00
