Abstract：
OBJECTIVE:To optimize the process parameters involved in the green synthesis of silver nanoparticles (G-SNPs) by aqueous extract of Rosa damascena petals and to evaluate the biocompatibility and anti cancer activity of the synthesized silver nanoparticles against human lung adenocarcinoma (A549). METHODS:The process variables that include concentration of extract, mixing ratio of reactants, silver salt concentration and interaction time were analyzed. The compatibility of the G-SNPs was verified by incubating with erythrocytes and the anticancer property of the G-SNPs against A549 cells was performed by MTT assay. RESULTS:Formation of G-SNPs was confirmed by the visual change in the colour of the reaction mixture from pale yellow to brown yellow. Surface plasmon resonance of synthesized G-SNPs was observed at 420 nm; the size of G-SNPs were analyzed by DLS and found to be in the range of (84.00±10.08) nm. Field emission scanning electron microscope and high resolution transmission electron microscopy analysis confirmed that the G-SNPs were fairly spherical. Fourier transform infrared spectroscopy spectroscopy and X-ray diffraction revealed the characteristic peaks of G-SNPs. Energy dispersive X-ray analysis showed a signal of silver around 3 keV. The synthesized G-SNPs exhibited anticancer activity as evidenced by the MTT assay. IC50 value of G-SNPs was found to be 80 μg/mL. CONCLUSION:The results of the present study suggest that G-SNPs can be synthesized rapidly within first minute of the reaction; they are biocompatible and possess anticancer activity against human lung adenocarcinoma.
journal_name
Asian Pac J Trop Medjournal_title
Asian Pacific journal of tropical medicineauthors
Venkatesan B,Subramanian V,Tumala A,Vellaichamy Edoi
10.1016/S1995-7645(14)60249-2subject
Has Abstractpub_date
2014-09-01 00:00:00pages
S294-300eissn
1995-7645issn
2352-4146pii
S1995-7645(14)60249-2journal_volume
7S1pub_type
杂志文章abstract：OBJECTIVE:To evaluate a new pharmacological activity/effect of linolenic acid (α- and γ-form) and conjugated-linoleic acid (CLA) causing antibacterial activity against Mycobacterium tuberculosis (Mtb). METHODS:The anti-Mtb activity/effect of linolenic acid and CLA were determined using different anti-Mtb indicator met...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/j.apjtm.2016.01.021
更新日期：2016-02-01 00:00:00
abstract：OBJECTIVE:To investigate the diuretic, hypotensive and renal effect of Opuntia ficus-indica in two different species in oral and intravenous administration. METHODS:Diuretic activity was evaluated in rats with the plant cladode gel and aqueous extract administrated orally, and was evaluated in rabbits with plant extra...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/j.apjtm.2017.08.016
更新日期：2017-09-01 00:00:00
abstract：:Captive reptiles, always more often present in domestic environment as pets, may harbor and excrete a large variety of zoonotic pathogens. Among them, Salmonella is the most well-known agent, whereas there are very scant data about infections by mycobacteria, chlamydiae and leptospirae in cold-blooded animals. However...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章,评审
doi：10.1016/j.apjtm.2017.07.020
更新日期：2017-08-01 00:00:00
abstract：OBJECTIVE:To investigate the antidiarrheal activity of the methanol leaf extract of Pterocarpus erinaceus in vivo. METHODS:The methanol leaf extract of Pterocarpus erinaceus was evaluated using different doses (100, 200 and 400 mg/kg body weight) orally for antidiarrheal activity using castor oil-induced diarrhea, cha...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/S1995-7645(12)60014-5
更新日期：2012-02-01 00:00:00
abstract：OBJECTIVE:To validate traditional claims of usefulness of the Indian plants in management of poisonous snakebite and evaluate the antivenom properties displayed by the alcoholic extracts of Andrographis paniculata (A. paniculata), Crateva magna (C. magna), Gloriosa superba (G. superba) and Hydrocotyle javanica (H. java...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/S1995-7645(11)60185-5
更新日期：2011-09-01 00:00:00
abstract：OBJECTIVE:To investigate the effect of ischemic precondition to protect ischemia-reperfusion injury and reduce IL-6 expression in the rats liver transplantation. METHODS:The rat portal vein infusion of autologous liver transplantation model were used. The rats were divided into ischemic preconditioning rats liver tran...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/S1995-7645(13)60045-0
更新日期：2013-05-13 00:00:00
abstract：OBJECTIVE:To compare the anti-atherosclerotic effects of two different extracts from the leaves of Mallotus furetianus by using rat model of atherosclerosis. METHODS:The air-dried powdered Mallotus furetianus leaves were extracted with ethanol and then evaporated. The ethanol extract was experienced Diaion HP-20 CC wi...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/S1995-7645(11)60212-5
更新日期：2011-11-01 00:00:00
abstract：OBJECTIVES:To test the hypothesis that concentration of amniotic fluid alpha-fetal protein (AFAFP) is increased in thalassemia fetus. METHODS:A total of 135 cases of amniocentesis admitted from July 2013 to December 2014 were included in this study. Among them 98 cases of normal fetuses were assigned into control grou...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/j.apjtm.2017.01.001
更新日期：2017-02-01 00:00:00
abstract：OBJECTIVE:To describe the epidemiology of snake bite in the region and attempt to compare proven Russell's viper with hump-nosed viper bites. METHODS:All snake bite admissions to the Toxicology Unit of Teaching Hospital Peradeniya over three year from 2006 were included. RESULTS:Of the 776 snakebites, 665(86%) were u...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/S1995-7645(11)60147-8
更新日期：2011-07-01 00:00:00
abstract：OBJECTIVE:To build the rat model of gastric precancerous lesions and discuss the effect of transplantation of mesenchymal stem cells (BMMSCs) on the pathological change. METHODS:The rat model of gastric precancerous lesions was built using N-methyl-N'-nitro-N'-nitrosoguanidine. After the intravenous transplantation of...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章,撤回出版物
doi：10.1016/j.apjtm.2015.11.006
更新日期：2015-12-01 00:00:00
abstract：OBJECTIVE:To determine the relationship between asymptomatic malaria parasitemia and some oxidative stress parameters in pregnant Nigerian women. METHODS:This is a cross-sectional study involving 130 normal pregnant women at various trimesters, who were attending antenatal clinic at the University of Nigeria Teaching ...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/S1995-7645(11)60076-X
更新日期：2011-03-01 00:00:00
abstract：OBJECTIVE:To determine the prevalence and intensity of infection and the risk factors associated with urinary schistosomiasis in pre-school and school aged children in Guma Local Government Area of Benue State, Nigeria. METHODS:Urine filtration technique using polycarbonate membrane filters was employed to process uri...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/S1995-7645(13)60188-1
更新日期：2014-01-01 00:00:00
abstract：OBJECTIVE:To induce pluripotent stem (IPS) cells from fibrocytes that are separated from liver cancer patients. METHODS:The fibrocytes were reprogrammed to IPS cells by lentiviral vector, stained and identified by immunohistochemistry. RESULTS:The IPS cells were successfully established from fibrocytes after infectio...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/S1995-7645(14)60032-8
更新日期：2014-04-01 00:00:00
abstract：:We present an atypical case of disseminated cutaneous leishmaniasis in the Sihuas district, located in the Andean valleys of Ancash-Peru. A 62-year-old man with no particular medical history presented multiple lesions located on the inferior abdomen, lumbar region and the right anterior thigh. Histological analysis fo...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/j.apjtm.2017.10.001
更新日期：2017-11-01 00:00:00
abstract：OBJECTIVE:To clone the virB12 gene in pET28a expression vector for production of recombinant protein to be used as antigenic component for future serological test development. METHODS:Brucella melitensis (B. melitensis) 16M strain was cultured and bacterial DNA was extracted by Bioneer AccuPrep® Genomic DNA Extraction...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/S1995-7645(12)60089-3
更新日期：2012-07-01 00:00:00
abstract：OBJECTIVE:To investigate the effect of the anthocyanin-rich extract of Hibiscus sabdariffa (H. sabdariffa) calyx on the viability of cadmium-treated U937 cells and cadmium-mediated activation of U937-derived macrophages. METHODS:The macrophage cell line U937 was treated with cadmium (0.1 μ mol/L) and later incubated w...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/S1995-7645(11)60241-1
更新日期：2012-01-01 00:00:00
abstract：:Hookworm infection is a relatively common cause of anemia in endemic areas. The most common hookworm species are Ancylostoma duodenale and Necator americanus. In this report we present a case of overt gastrointestinal bleeding because of hookworm infection. Capsule endoscopy revealed many hookworms in the lumen of pro...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/S1995-7645(12)60051-0
更新日期：2012-04-01 00:00:00
abstract：OBJECTIVE:To study the expression of tumor necrosis factor receptor-associated protein 1 (TRAP1) in gastric cancer tissue and its correlation with malignant biology. METHODS:Gastric cancer tissue and adjacent normal tissue were collected, and mRNA content and protein content of TRAP1 were detected; gastric cancer cell...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/j.apjtm.2015.12.014
更新日期：2016-01-01 00:00:00
abstract：OBJECTIVE:To delineate the frequency of occurrence of bla(CTX-M), bla(TEM), and bla(SHV) in Enterobacteriaceae from North-Indian tertiary hospital. METHODS:A random collection of a subset of 45 Escherichia coli (E. coli) and 28 Klebsiella pneumoniae (K. pneumoniae) that was resistant to a third generation cephalospori...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/S1995-7645(11)60046-1
更新日期：2011-02-01 00:00:00
abstract：OBJECTIVE:To isolate and characterize antidiabetic component (bioactivity-guided fractionation) from hydro alcoholic extract of Ocimum sanctum (O. sanctum) aerial part. METHODS:Ten fractions (F1-F10) were isolated from hydro alcoholic extract of O. sanctum aerial part by column chromatography. All the fractions F1 to ...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/S1995-7645(11)60086-2
更新日期：2011-04-01 00:00:00
abstract：OBJECTIVE:To screen for Escherichia coli (E. coli) resistant to tetracycline, followed by identification of tet efflux genes by polymerase chain reaction (PCR). In addition, detection of tetracycline residues in chicken livers and kidneys were conducted using high performance liquid chromatography-tandem quadrupole mas...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/S1995-7645(13)60125-X
更新日期：2013-09-01 00:00:00
abstract：OBJECTIVE:To determine the range and incidence of complications associated with Plasmodium vivax (P. vivax) malaria. METHODS:A retrospective analysis was performed of all patients of P. vivax malaria admitted in Kasturba Medical College, Manipal between January and December, 2010. Patients with mixed malarial infectio...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/S1995-7645(11)60251-4
更新日期：2012-01-01 00:00:00
abstract：OBJECTIVE:To evaluate antioxidant and radical scavenging activities of organic extracts from fruit, roots and aerial parts of Fagonia cretica. METHODS:Shed dried and powdered plant parts were initially extracted in methanol and subsequently partitioned in n-hexane, chloroform, ethyl acetate and 1-butanol successively....
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/S1995-7645(14)60277-7
更新日期：2014-09-01 00:00:00
abstract：OBJECTIVE:To confirm dengue infection among Russian tourists returned from Southeast and Mexico in 2010-2013 with clinical signs of infection. METHODS:Blood and serum samples from patients were collected. NS1 antigen and human IgM/IgG antibodies to dengue virus were identified using commercial tests manufactured by "S...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/S1995-7645(14)60194-2
更新日期：2015-02-01 00:00:00
abstract：OBJECTIVE:To assess the effect potency, and the immunomodulatory response of garlic oil extract in enhancing the host's immune system against the disorders caused by Schistosoma mansoni (S. mansoni) in mice at different stages of worm maturation. METHODS:A total of 70 male CD-1 Swiss albino mice were divided into 7 gr...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/j.apjtm.2015.11.016
更新日期：2015-12-01 00:00:00
abstract：OBJECTIVE:To investigate the protective role of Cardiospermum halicacabum (C. halicacabum) leaf extract on glycoprotein metabolism in streptozotocin (STZ)-induced diabetic rats. METHODS:Diabetes was induced in male albino Wistar rats by intraperitonial administration of STZ. The C. halicacabum leaf extract (CHE) was a...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/S1995-7645(12)60178-3
更新日期：2012-12-01 00:00:00
abstract：OBJECTIVE:To investigate the effects of pectic polysaccharides extracted from Rauwolfia verticillata (Lour.) Baill.var.hainanensis Tsiang on an experimental murine colitis model. METHODS:Experimental colitis was induced by dextran sulfate sodium (DSS), and mice were divided into 4 groups: control, DSS alone, DSS plus ...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/S1995-7645(14)60306-0
更新日期：2015-02-01 00:00:00
abstract：OBJECTIVE:To determine the effects of environmental parameters of larval habitats on distribution and abundance of anopheline mosquitoes in Rudan county of Iran. METHODS:This cross-sectional study was conducted during the mosquito breeding season from February 2010 to October 2011. The anopheline larvae were collected...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/S1995-7645(13)60087-5
更新日期：2013-07-01 00:00:00
abstract：OBJECTIVE:To determine resistance status of Culex species to different class of insecticides and assess the major anti-mosquito strategies employed by urban households and their possible effects on malaria acquisition. METHODS:Structured questionnaires were randomly administered to obtain information on demographic ch...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/S1995-7645(13)60153-4
更新日期：2013-11-01 00:00:00
abstract：OBJECTIVE:To investigate the composition of volatile compounds in the different accessions of Perilla frutescens (P. frutescens) collected from various habitats of China and Japan. METHODS:In the present study, the essential oil from the leaves of P. frutescens cultivars from China and Japan was extracted by hydro-dis...
journal_title：Asian Pacific journal of tropical medicine
pub_type： 杂志文章
doi：10.1016/j.apjtm.2017.07.004
更新日期：2017-07-01 00:00:00
