A variant of DC-SIGN gene promoter associated with resistance to HIV-1 in serodiscordant couples in Burkina Faso.

Abstract:

OBJECTIVE:To study the involvement of variations in 4 genes associated with susceptibility and/or protection against HIV-1 in serodiscordant couples in Burkina Faso, namely, genes encoding HLA-B57, interferon regulatory factor 1 (IRF1), dendritic cell-specific ICAM3-grabbing nonintegrin (DC-SIGN) and CCR5 delta 32 (CCR5Δ32). METHODS:Two DC-SIGN and two IRF1 single nucleotide polymorphisms (SNPs) as well as HLA-B57*01 and CCR5Δ32 alleles were genotyped in 51 serodiscordant couples in Burkina Faso. DC-SIGN, IRF1 and HLA-B57*01 genotyping was carried out by real time PCR using TaqMan assays (Applied Biosystems, USA and Sacace Biotechnologies, Italy). CCR5Δ32 deletion was investigated by PCR. RESULTS:The two SNPs of DC-SIGN promoter showed a significant genotypic difference in serodiscordant couples. After multivariate analysis, only the association between DC-SIGN rs2287886 and HIV-1 remained significant (P<0.01). No association was found between IRF1 SNPs and HIV-1 infection. CCR5Δ32 wild type allele was found in 100% of serodiscordant couples. A high frequency of HLA-B57*01 allele was found in the HIV-positive (78%) compared with HIV-negative group (51%), however this difference was no longer significant after the correction of the sex confounding effect in the logistic regression model. CONCLUSIONS:Our study suggests a protective role of a variation of DC-SIGN promoter and genetic resistance to HIV-1 in serodiscordant couples in Burkina Faso.

journal_name

Asian Pac J Trop Med

authors

Kagoné TS,Bisseye C,Méda N,Testa J,Pietra V,Kania D,Yonli AT,Compaoré TR,Nikiéma JB,de Souza C,Simpore J

doi

10.1016/S1995-7645(14)60211-X

subject

Has Abstract

pub_date

2014-09-01 00:00:00

pages

S93-6

eissn

1995-7645

issn

2352-4146

pii

S1995-7645(14)60211-X

journal_volume

7S1

pub_type

杂志文章
  • Therapeutic effect of Captopril on rheumatoid arthritis in rats.

    abstract:OBJECTIVE:To investigate the therapeutic effect of the intervention treatment with different doses of Captopril on TNF-αcontents in serum of rheumatoid arthritis (RA) rats, and to provide the theoretical proofs for clinical application of Captopril in treatments of rheumatoid diseases. METHODS:Fifty Wistar rats were r...

    journal_title:Asian Pacific journal of tropical medicine

    pub_type: 杂志文章

    doi:10.1016/S1995-7645(14)60175-9

    authors: Liu HM,Wang KJ

    更新日期:2014-12-01 00:00:00

  • Antihaemolytic and snake venom neutralizing effect of some Indian medicinal plants.

    abstract:OBJECTIVE:To validate traditional claims of usefulness of the Indian plants in management of poisonous snakebite and evaluate the antivenom properties displayed by the alcoholic extracts of Andrographis paniculata (A. paniculata), Crateva magna (C. magna), Gloriosa superba (G. superba) and Hydrocotyle javanica (H. java...

    journal_title:Asian Pacific journal of tropical medicine

    pub_type: 杂志文章

    doi:10.1016/S1995-7645(11)60185-5

    authors: Kumarapppan C,Jaswanth A,Kumarasunderi K

    更新日期:2011-09-01 00:00:00

  • Expression of TRAP1 in gastric cancer tissue and its correlation with malignant biology.

    abstract:OBJECTIVE:To study the expression of tumor necrosis factor receptor-associated protein 1 (TRAP1) in gastric cancer tissue and its correlation with malignant biology. METHODS:Gastric cancer tissue and adjacent normal tissue were collected, and mRNA content and protein content of TRAP1 were detected; gastric cancer cell...

    journal_title:Asian Pacific journal of tropical medicine

    pub_type: 杂志文章

    doi:10.1016/j.apjtm.2015.12.014

    authors: Han P,Wang QL,Zhang X

    更新日期:2016-01-01 00:00:00

  • Preventive and therapeutic effect of simvastatin on secondary inflammatory damage of rats with cerebral hemorrhage.

    abstract:OBJECTIVE:To investigate the preventive and therapeutic effect and mechanism of simvastatin on secondary inflammatory damage of rats with cerebral hemorrhage. METHODS:Sixty SD rat aged 9-12 weeks were chosen and divided into the control group, model group and simvastatin-treated group randomly with 20 rats in each gro...

    journal_title:Asian Pacific journal of tropical medicine

    pub_type: 杂志文章

    doi:10.1016/j.apjtm.2017.01.003

    authors: Zhou HX,Gao LH,Meng LL,Zhang YX,Wei ZF,Si DW

    更新日期:2017-02-01 00:00:00

  • Malaria helminth co-infections and their contribution for aneamia in febrile patients attending Azzezo health center, Gondar, Northwest Ethiopia: a cross sectional study.

    abstract:OBJECTIVE:To assess the prevalence of malaria helminth co-infections and their contribution for aneamia in febrile patients attending Azzezo health center, Gondar, Northwest Ethiopia. METHODS:A cross section study was conducted among febrile patients attending Azezo health center from February-March 30, 2011. Convenie...

    journal_title:Asian Pacific journal of tropical medicine

    pub_type: 杂志文章

    doi:10.1016/S1995-7645(12)60147-3

    authors: Alemu A,Shiferaw Y,Ambachew A,Hamid H

    更新日期:2012-10-01 00:00:00

  • Depth of anaesthesia monitors and the latest algorithms.

    abstract::This paper reviews the existing depth of anaesthesia (DoA) monitors and their algorithms and also proposes to improve their performance from four aspects. An ideal DoA monitor should be able to suggest a personalised drug dosage, to predict and provide early warnings when dosages are inappropriate, to be portable and ...

    journal_title:Asian Pacific journal of tropical medicine

    pub_type: 杂志文章,评审

    doi:10.1016/S1995-7645(14)60070-5

    authors: Li TN,Li Y

    更新日期:2014-06-01 00:00:00

  • Mosquito larvicidal and ovicidal properties of Eclipta alba (L.) Hassk (Asteraceae) against chikungunya vector, Aedes aegypti (Linn.) (Diptera: Culicidae).

    abstract:OBJECTIVE:The present study deals with the investigation of larvicidal and ovicidal activities of benzene, hexane, ethyl acetate, methanol and chloroform leaf extract of Eclipta alba (E. alba) against dengue vector, Aedes aegypti (Ae. Aegypti). METHODS:Twenty five early III instar larvae of Ae. aegypti was exposed to ...

    journal_title:Asian Pacific journal of tropical medicine

    pub_type: 杂志文章

    doi:10.1016/S1995-7645(11)60026-6

    authors: Govindarajan M,Karuppannan P

    更新日期:2011-01-01 00:00:00

  • Enhancing effect of ultrasound-mediated microbubble destruction on gene delivery into rat kidney via different administration routes.

    abstract:OBJECTIVE:To investigate the efficiency of β-galactosidase gene transfer into rat kidney with ultrasound-mediated microbubble destruction via different injection routes. METHODS:A total of 25 Wistar rats were randomly divided into 5 groups. Four groups received a mixture of optison microbubbles (0.2 mL) and lacz plasm...

    journal_title:Asian Pacific journal of tropical medicine

    pub_type: 杂志文章

    doi:10.1016/S1995-7645(12)60099-6

    authors: Chen JX,Ma Q,Wu H,Zhou A,Chen X,Peng YM,Liu FY,Cheng MC

    更新日期:2012-07-01 00:00:00

  • Escherichia coli tetracycline efflux determinants in relation to tetracycline residues in chicken.

    abstract:OBJECTIVE:To screen for Escherichia coli (E. coli) resistant to tetracycline, followed by identification of tet efflux genes by polymerase chain reaction (PCR). In addition, detection of tetracycline residues in chicken livers and kidneys were conducted using high performance liquid chromatography-tandem quadrupole mas...

    journal_title:Asian Pacific journal of tropical medicine

    pub_type: 杂志文章

    doi:10.1016/S1995-7645(13)60125-X

    authors: S N AB,B M AM,A S AA,A E E,I Y M

    更新日期:2013-09-01 00:00:00

  • Helianthus tuberosus (Jerusalem artichoke) tubers improve glucose tolerance and hepatic lipid profile in rats fed a high-fat diet.

    abstract:OBJECTIVES:To analyze the effects of feeding Helianthus tuberosus (HT) tubers on glucose tolerance and lipid profile in rats fed a high-fat diet (HFD). METHODS:A normal HFD or HFD including 10 w/w% HT tubers (HFD + HT) was fed to F334/Jcl rats. After 10 weeks, organ weights, glucose tolerance, and lipid profile were a...

    journal_title:Asian Pacific journal of tropical medicine

    pub_type: 杂志文章

    doi:10.1016/j.apjtm.2017.03.028

    authors: Okada N,Kobayashi S,Moriyama K,Miyataka K,Abe S,Sato C,Kawazoe K

    更新日期:2017-05-01 00:00:00

  • Spectrum of complications associated with Plasmodium vivax infection in a tertiary hospital in South-Western India.

    abstract:OBJECTIVE:To determine the range and incidence of complications associated with Plasmodium vivax (P. vivax) malaria. METHODS:A retrospective analysis was performed of all patients of P. vivax malaria admitted in Kasturba Medical College, Manipal between January and December, 2010. Patients with mixed malarial infectio...

    journal_title:Asian Pacific journal of tropical medicine

    pub_type: 杂志文章

    doi:10.1016/S1995-7645(11)60251-4

    authors: Naha K,Dasari S,Prabhu M

    更新日期:2012-01-01 00:00:00

  • Efficacy evaluation and kinetic study of biosorption of nickel and zinc by bacteria isolated from stressed conditions in a bubble column.

    abstract:OBJECTIVE:To investigate the biosorption potential of isolated bacteria as an alternative biosorbent material for the removal of zinc and nickel from aqueous solution in a bubble column bioreactor. METHORDS:In this study from four points of waste water treatment plant, some Gram-positive and Gram-negative bacteria und...

    journal_title:Asian Pacific journal of tropical medicine

    pub_type: 杂志文章

    doi:10.1016/S1995-7645(14)60231-5

    authors: Arjomandzadegan M,Rafiee P,Moraveji MK,Tayeboon M

    更新日期:2014-09-01 00:00:00

  • Acetylcholinesterase, butyrylcholinesterase and paraoxonase 1 activities in rats treated with cannabis, tramadol or both.

    abstract:OBJECTIVE:To investigate the effect of Cannabis sativa resin and/or tramadol, two commonly drugs of abuse on acetylcholinesterase and butyrylcholinesterase activities as a possible cholinergic biomarkers of neurotoxicity induced by these agents. METHODS:Rats were treated with cannabis resin (5, 10 or 20 mg/kg) (equiva...

    journal_title:Asian Pacific journal of tropical medicine

    pub_type: 杂志文章

    doi:10.1016/j.apjtm.2016.09.009

    authors: Abdel-Salam OM,Youness ER,Khadrawy YA,Sleem AA

    更新日期:2016-11-01 00:00:00

  • RETRACTED: Effect of thioredoxin-interacting protein on Wnt/β-catenin signaling pathway and diabetic myocardial infarction.

    abstract:OBJECTIVE:To explore the regulatory role of thioredoxin-interacting protein (TXNIP) in Wnt/β-catenin signaling pathway and therefore to elucidate its function in diabetic myocardial infarction. METHODS:Diabetic myocardial infarction models were generated in mice. The expression levels of TXNIP and β-catenin and level ...

    journal_title:Asian Pacific journal of tropical medicine

    pub_type: 杂志文章,撤回出版物

    doi:10.1016/j.apjtm.2015.10.010

    authors: Yu H,Zhao XX,Shan XH,Li P,Chen T

    更新日期:2015-11-01 00:00:00

  • RETRACTED: Effect of transplantation of BMMSCs on pathological change of gastric precancerous lesions of rats.

    abstract:OBJECTIVE:To build the rat model of gastric precancerous lesions and discuss the effect of transplantation of mesenchymal stem cells (BMMSCs) on the pathological change. METHODS:The rat model of gastric precancerous lesions was built using N-methyl-N'-nitro-N'-nitrosoguanidine. After the intravenous transplantation of...

    journal_title:Asian Pacific journal of tropical medicine

    pub_type: 杂志文章,撤回出版物

    doi:10.1016/j.apjtm.2015.11.006

    authors: Lin ZL,Zheng GW,Zhang L,Zheng JT,Chen H

    更新日期:2015-12-01 00:00:00

  • Relationship between gene polymorphisms and prostate cancer risk.

    abstract:OBJECTIVE:To investigate the relationship between genetic factor and prostate cancer (Pca) risk and the possible cause in it. METHODS:The polymorphisms of cytochrome P450 family 17 (CYPl7) rs743572, p27 V109G and androgen receptor (AR) gene CAG repeat length in peripheral blood from 70 cases and 70 controls were detec...

    journal_title:Asian Pacific journal of tropical medicine

    pub_type: 杂志文章

    doi:10.1016/j.apjtm.2015.06.005

    authors: Han QH,Shan ZJ,Hu JT,Zhang N,Zhang XP

    更新日期:2015-07-01 00:00:00

  • Induction of deletion mutation on ompR gene of Salmonella enterica serovar Typhi isolates from asymptomatic typhoid carriers to evolve attenuated strains for vaccine development.

    abstract:OBJECTIVE:To develop attenuated strains of Salmonella enterica serovar Typhi (S. typhi) for the candidate vaccine by osmolar stress. METHODS:S. typhi SS3 and SS5 strains were isolated from asymptomatic typhoid carriers in Namakkal, Tamil Nadu, India. Both strains were grown in LB (Luria Bertani) medium supplemented wi...

    journal_title:Asian Pacific journal of tropical medicine

    pub_type: 杂志文章

    doi:10.1016/S1995-7645(14)60165-6

    authors: Senthilkumar B,Anbarasu K,Senbagam D,Rajasekarapandian M

    更新日期:2014-12-01 00:00:00

  • Free radical scavenging property and antiproliferative activity of Rhodiola imbricata Edgew extracts in HT-29 human colon cancer cells.

    abstract:OBJECTIVE:To investigate the in vitro antioxidant and antiproliferative activity of rhizome extracts of Rhodiola imbricata (R. imbricata) in HT-29 human colon cancer cell line. METHODS:The successively extracted rhizome of R. imbricata using various solvents was analyzed for their total phenolics, tannins and flavonoi...

    journal_title:Asian Pacific journal of tropical medicine

    pub_type: 杂志文章

    doi:10.1016/S1995-7645(12)60194-1

    authors: Senthilkumar R,Parimelazhagan T,Chaurasia OP,Srivastava RB

    更新日期:2013-01-01 00:00:00

  • Clostridium difficile infection: a review of the literature.

    abstract::Clostridium difficile is a Gram-positive, strictly anaerobic, spore-forming bacterium. It is the most common cause of antibiotic-associated diarrhea in hospitals and other healthcare facilities and is of significant concern because of the increasing morbidity and mortality rates as well as increased health care costs....

    journal_title:Asian Pacific journal of tropical medicine

    pub_type: 杂志文章

    doi:10.1016/S1995-7645(14)60197-8

    authors: Khan FY,Elzouki AN

    更新日期:2014-09-01 00:00:00

  • Identifications of drug resistance mutations among antiretroviral treatment naive HIV-1 patients in Peninsular Malaysia.

    abstract:OBJECTIVE:To determine drug resistance mutations and the HIV-1 subtypes among antiretroviral treatment naive HIV-1 patients in Peninsular Malaysia. METHODS:A total of 45 samples from four hospitals that provide HIV viral load services were subjected to the amplification of the protease and two third of reverse transcr...

    journal_title:Asian Pacific journal of tropical medicine

    pub_type: 杂志文章

    doi:10.1016/j.apjtm.2016.12.005

    authors: Zain RM,Ibrahim N,Ismail S,Suppiah J,Mat Rahim NA,Thayan R

    更新日期:2017-01-01 00:00:00

  • Association of glycosylated hemoglobin level with lipid ratio and individual lipids in type 2 diabetic patients.

    abstract:OBJECTIVE:To study the correlation of lipid ratios and individual lipid indexes of patients with type 2 diabetes with glycosylated hemoglobin (HbA(1c)). METHODS:Samples were collected from 128 type 2 diabetic patients (aged 19-90 years; male 72, female 56). The sera were analyzed for HbA(1c), total cholesterol (TC), t...

    journal_title:Asian Pacific journal of tropical medicine

    pub_type: 杂志文章

    doi:10.1016/S1995-7645(12)60080-7

    authors: Yan Z,Liu Y,Huang H

    更新日期:2012-06-01 00:00:00

  • The phylogenetic and evolutionary history of Kokobera virus.

    abstract:OBJECTIVE:To estimate the genetic diversity of Kokobera virus, the date of origin and the spread among different viruses in the endemic regions of Australia. METHODS:Two datasets were built. The first consisting of 29 sequences of the NS5/3' UTR region of Kokobera group downloaded from GenBank, the second including on...

    journal_title:Asian Pacific journal of tropical medicine

    pub_type: 杂志文章

    doi:10.1016/j.apjtm.2016.07.028

    authors: Blasi A,Lo Presti A,Cella E,Angeletti S,Ciccozzi M

    更新日期:2016-10-01 00:00:00

  • Mechanism of Japanese encephalitis virus genotypes replacement based on human, porcine and mosquito-originated cell lines model.

    abstract:OBJECTIVE:To examine the multiplication efficiency Japanese encephalitis virus (JEV) genotype I (GI) and genotype III (GIII) of different cell lines which originated from human, porcine, mosquitoes in order to prove mechanism of JEV GI replacement JEV GIII since it emerging in nature recent decades. METHODS:The mixtur...

    journal_title:Asian Pacific journal of tropical medicine

    pub_type: 杂志文章

    doi:10.1016/j.apjtm.2016.03.007

    authors: Do LP,Bui TM,Phan NT

    更新日期:2016-04-01 00:00:00

  • Expression and significance of MMP3 in synovium of knee joint at different stage in osteoarthritis patients.

    abstract:OBJECTIVE:To investigate the expression and significance of MMP-3 in synovium of knee joint at different stage in osteoarthritis (OA) patients. METHODS:Knee synovial tissue were collected in 90 OA patients (the OA group). Patients in the OA group was divided into 3 subgroups: grade I subgroup (n=30), grade II subgroup...

    journal_title:Asian Pacific journal of tropical medicine

    pub_type: 杂志文章

    doi:10.1016/S1995-7645(14)60042-0

    authors: Chen JJ,Huang JF,Du WX,Tong PJ

    更新日期:2014-04-01 00:00:00

  • Evaluation of rabbit antibody response against 8 and 16 kDa recombinant subunits of antigen B from Echinococcus granulosus.

    abstract:OBJECTIVE:To immunize rabbits with 12 and 16 kDa recombinant subunits of antigen B from Echinococcus granulosus (E. granulosus) and measuring polyclonal antibody and humoral immune response using ELISA and gel diffusion. METHODS:Two mentioned antigens were cloned and expressed in expression vector and purified by affi...

    journal_title:Asian Pacific journal of tropical medicine

    pub_type: 杂志文章

    doi:10.1016/S1995-7645(12)60058-3

    authors: Abdi J,Kazemi B,Karimfar MH,Rokni MB

    更新日期:2012-05-01 00:00:00

  • bla(CTX-M), bla(TEM), and bla(SHV) in Enterobacteriaceae from North-Indian tertiary hospital: high occurrence of combination genes.

    abstract:OBJECTIVE:To delineate the frequency of occurrence of bla(CTX-M), bla(TEM), and bla(SHV) in Enterobacteriaceae from North-Indian tertiary hospital. METHODS:A random collection of a subset of 45 Escherichia coli (E. coli) and 28 Klebsiella pneumoniae (K. pneumoniae) that was resistant to a third generation cephalospori...

    journal_title:Asian Pacific journal of tropical medicine

    pub_type: 杂志文章

    doi:10.1016/S1995-7645(11)60046-1

    authors: Shahid M,Singh A,Sobia F,Rashid M,Malik A,Shukla I,Khan HM

    更新日期:2011-02-01 00:00:00

  • Hepatoprotective and cytoprotective properties of Hyptis suaveolens against oxidative stress-induced damage by CCl(4) and H(2)O(2).

    abstract:OBJECTIVE:To investigate capacity of Hyptis suaveolens (H. suaveolens) methanol extract as an antioxidant to protect against carbon tetrachloride (CCl(4))-induced oxidative stress, hepatotoxicity in Albino Wistar rats and cytoprotective effect of hydrogen peroxide (H(2)O(2)) induced cell death in HepG(2) cell line. ME...

    journal_title:Asian Pacific journal of tropical medicine

    pub_type: 杂志文章

    doi:10.1016/S1995-7645(12)60162-X

    authors: Ghaffari H,Ghassam BJ,Prakash HS

    更新日期:2012-11-01 00:00:00

  • Development of quality control parameters for the standardization of Limonia acidissima L. leaf and stem.

    abstract:OBJECTIVE:To evaluate the pharmacognostic characters of Limonia acidissima L. (L. acidissima) leaf and stem, an important traditional medicinal plant. METHODS:The present study provides pharmacognostic, physicochemical and phytochemical details of leaf and stem of L. acidissima. Micro and macroscopic characters were a...

    journal_title:Asian Pacific journal of tropical medicine

    pub_type: 杂志文章

    doi:10.1016/S1995-7645(14)60240-6

    authors: Pandavadra M,Chanda S

    更新日期:2014-09-01 00:00:00

  • Comparative analysis of biological characteristics of adult mesenchymal stem cells with different tissue origins.

    abstract:OBJECTIVE:To invest the differences among mesenchymal stem cells (MSCs) derived from different tissues and their impacts on clinical applications. METHODS:In this study, MSCs were isolated from adipose tissue (AD), umbilical cord tissue (UC), and menstrual blood (Men) and compared their biological characteristics in t...

    journal_title:Asian Pacific journal of tropical medicine

    pub_type: 杂志文章

    doi:10.1016/j.apjtm.2015.07.022

    authors: Chen JY,Mou XZ,Du XC,Xiang C

    更新日期:2015-09-01 00:00:00

  • Phytochemical analysis, hepatoprotective and antioxidant activity of Alchornea cordifolia methanol leaf extract on carbon tetrachloride-induced hepatic damage in rats.

    abstract:OBJECTIVE:To investigate the hepatoprotective and antioxidant activities of Alchornea cordifolia (A. cordifolia) leaf extract. METHODS:Various solvent fractions of the methanol extract of the leaf of the plant A. cordifolia Mull. Arg (Fam: Euphorbiaceae) were evaluated for hepatoprotective activity by carbon tetrachlo...

    journal_title:Asian Pacific journal of tropical medicine

    pub_type: 杂志文章

    doi:10.1016/S1995-7645(12)60041-8

    authors: Osadebe PO,Okoye FB,Uzor PF,Nnamani NR,Adiele IE,Obiano NC

    更新日期:2012-04-01 00:00:00