Abstract:
OBJECTIVE:To investigate the levels of serum cortisol in patients with uncomplicated Plasmodium falciparum (P. falciparum) malaria in an area of unstable malaria transmission in eastern Sudan. METHODS:The concentrations of cortisol were measured in sera of 25 patients with uncomplicated P. falciparum malaria (at presentation, 24 h and 7 d later) and 25 healthy volunteers using radioimmunoassay gamma counter. RESULTS:There was no significant difference in mean (SD) of total cortisol levels in patients with malaria in comparison with the control group; 602.2 (369.6) vs. 449.2(311.7) ng/mL, P=0.12. In patients with uncomplicated P. falciparum malaria, the mean (SD) presenting cortisol levels were significantly higher in comparison to the levels on day 7; 602.2 (369.6) vs. 373.6(139.1) ng/mL, P=0.009. In the patients with uncomplicated P. falciparum malaria (on presentation) cortisol levels were not correlated with initial temperature or the presenting parasitaemia. CONCLUSIONS:Thus, cortisol levels were not significantly different between the patients and the controls.
journal_name
Asian Pac J Trop Medjournal_title
Asian Pacific journal of tropical medicineauthors
Ibrahim EA,Kheir MM,Elhardello OA,Almahi WA,Ali NI,Elbashir MI,Ishag Adoi
10.1016/S1995-7645(11)60056-4subject
Has Abstractpub_date
2011-02-01 00:00:00pages
146-7issue
2eissn
1995-7645issn
2352-4146pii
S1995-7645(11)60056-4journal_volume
4pub_type
杂志文章abstract:OBJECTIVE:To analyze the effects of Ageratum conyzoides L. on the monosodium iodoacetate induced osteoarthritis rats. METHODS:Thin layer chromatography was performed to analyze the constituents of the babandotan extract leaves. White male Sprague-Dawley rats used in this study were divided into 6 groups: normal contro...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/j.apjtm.2017.03.006
更新日期:2017-03-01 00:00:00
abstract:OBJECTIVE:To investigate antidiabetic, antihyperlipidemic and antioxidant activity of methanol extract of Tectona grandis (T. grandis) flowers (METGF) in streptozotocin (STZ) induced diabetic rats to supports its traditional use. METHODS:Acute toxicity study of METGF was carried out in rat to determine its dose for th...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/S1995-7645(11)60160-0
更新日期:2011-08-01 00:00:00
abstract:OBJECTIVE:To survey the prevalence severe diarrhea arising from these bacteria in children under 5 years old in Marvdasht. METHODS:In this study faecal sample from 615 children aged <5 years old who were hospitalized for gastroenteritis in Fars hospitals in Iran were collected and then enriched in Escherichia coli (E....
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/S1995-7645(14)60182-6
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVE:To determine the content of benzyl glucosinolate (BG) in the pulp and the seed and investigate the anti-cancer activity of its hydrolysis product in Carica papaya L. METHODS:Determination of BG was performed on an Hypersil BDS C(18) column at the wavelength of 214 nm with 0.1% trifluoroacetic acid (TFA) aque...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/S1995-7645(12)60030-3
更新日期:2012-03-01 00:00:00
abstract:OBJECTIVE:To study the expression of caveolin-1 in colorectal adenocarcinoma tissues and its correlation with microlymphatic vessel density (LMVD), and to investigate the clinical pathological prognostic significance of caveolin-1 and LMVD in patients with colorectal cancer. METHODS:The expression of caveolin-1 and LM...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/j.apjtm.2015.07.004
更新日期:2015-08-01 00:00:00
abstract:OBJECTIVE:To estimate the genetic diversity of Kokobera virus, the date of origin and the spread among different viruses in the endemic regions of Australia. METHODS:Two datasets were built. The first consisting of 29 sequences of the NS5/3' UTR region of Kokobera group downloaded from GenBank, the second including on...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/j.apjtm.2016.07.028
更新日期:2016-10-01 00:00:00
abstract:OBJECTIVE:To investigate the hepatoprotective and antioxidant activities of Alchornea cordifolia (A. cordifolia) leaf extract. METHODS:Various solvent fractions of the methanol extract of the leaf of the plant A. cordifolia Mull. Arg (Fam: Euphorbiaceae) were evaluated for hepatoprotective activity by carbon tetrachlo...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/S1995-7645(12)60041-8
更新日期:2012-04-01 00:00:00
abstract:OBJECTIVE:To explore the application of cervical cancer screening system, TruScreen in detecting atypical squamous cell of undetermined significance (ASCUS) patients. METHODS:A total of 42 cases were selected, who were diagnosed as ASCUS by thinprep cytologic test (TCT). Area from site 15 to 20, site 21 to 32 were det...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/S1995-7645(11)60170-3
更新日期:2011-08-01 00:00:00
abstract:OBJECTIVE:To test the anticancer potential activity of the combination of thymoquinone (TQ) and resveratrol (RES) against breast cancer in mice. METHODS:The antiproliferative activity of TQ, RES and their combination was assessed against three breast cancer cell lines and one normal cells using MTT assay. The combinat...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/j.apjtm.2017.03.026
更新日期:2017-04-01 00:00:00
abstract:OBJECTIVE:To compare the anti-atherosclerotic effects of two different extracts from the leaves of Mallotus furetianus by using rat model of atherosclerosis. METHODS:The air-dried powdered Mallotus furetianus leaves were extracted with ethanol and then evaporated. The ethanol extract was experienced Diaion HP-20 CC wi...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/S1995-7645(11)60212-5
更新日期:2011-11-01 00:00:00
abstract:OBJECTIVE:To explore the regulatory role of thioredoxin-interacting protein (TXNIP) in Wnt/β-catenin signaling pathway and therefore to elucidate its function in diabetic myocardial infarction. METHODS:Diabetic myocardial infarction models were generated in mice. The expression levels of TXNIP and β-catenin and level ...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章,撤回出版物
doi:10.1016/j.apjtm.2015.10.010
更新日期:2015-11-01 00:00:00
abstract:OBJECTIVE:To provide further evidence for the ethnomedicinal use of the Eastern Nigeria mistletoe, Loranthus micranthus (L. micranthus), as an immunostimulant. METHODS:Solvent fractions from the crude extract of the mistletoe plant was obtained and screened by the cell mediated delayed type hypersensitivity reaction (...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/S1995-7645(11)60137-5
更新日期:2011-07-01 00:00:00
abstract:OBJECTIVE:To clone the virB12 gene in pET28a expression vector for production of recombinant protein to be used as antigenic component for future serological test development. METHODS:Brucella melitensis (B. melitensis) 16M strain was cultured and bacterial DNA was extracted by Bioneer AccuPrep® Genomic DNA Extraction...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/S1995-7645(12)60089-3
更新日期:2012-07-01 00:00:00
abstract:OBJECTIVE:To determine the phytochemical composition, antioxidant and anticancer activities of ethanolic and water leaves extracts of Annona muricata (A. muricata) from the Eastern Uganda. METHODS:Phytochemical screening was conducted using standard qualitative methods and a Chi-square goodness of fit test was used to...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/S1995-7645(14)60258-3
更新日期:2014-09-01 00:00:00
abstract:OBJECTIVE:To explore the regulation effect of Rheum palmatum (R. palmatum) L. on NF-κB signaling pathway of ALF mice. METHODS:The intraperitoneal injection of d-GalN/LPS was employed for the model building. Mice in the treatment group and positive control group were given the R. palmatum L. and bifendate before the mo...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/j.apjtm.2015.09.011
更新日期:2015-10-01 00:00:00
abstract:OBJECTIVE:To assess the prevalence of malaria helminth co-infections and their contribution for aneamia in febrile patients attending Azzezo health center, Gondar, Northwest Ethiopia. METHODS:A cross section study was conducted among febrile patients attending Azezo health center from February-March 30, 2011. Convenie...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/S1995-7645(12)60147-3
更新日期:2012-10-01 00:00:00
abstract:OBJECTIVE:To confirm dengue infection among Russian tourists returned from Southeast and Mexico in 2010-2013 with clinical signs of infection. METHODS:Blood and serum samples from patients were collected. NS1 antigen and human IgM/IgG antibodies to dengue virus were identified using commercial tests manufactured by "S...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/S1995-7645(14)60194-2
更新日期:2015-02-01 00:00:00
abstract::Toxoplasmosis is a globally distributed parasitic protozoan disease, caused by Toxoplasma gondii. The infection can result in more severe symptoms with potentially life-threatening in case of immunocompromised individuals. Sulfadiazine and pyrimethamine are the two drugs used as a part of standard therapy for toxoplas...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章,评审
doi:10.1016/j.apjtm.2016.06.012
更新日期:2016-08-01 00:00:00
abstract:OBJECTIVE:To investigate the differential expression of microRNA (miRNA) in colon between ulcerative colitis (UC) and ulcerative colitis related colorectal cancer (UCRCC). METHODS:An UC mouse model was built by dextran sodium sulfate, and an UCRCC mouse model by dextran sodium sulfate and 1,2-diformylhydrazine. RNAs w...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/S1995-7645(13)60174-1
更新日期:2013-12-01 00:00:00
abstract:OBJECTIVE:To explore the larvicidal and pupicidal activity of Euphorbia hirta (E. hirta) leaf extract and Bacillus sphaericus (B. sphaericus) against the malarial vector, Anopheles stephensi (An. stephensi). METHODS:The larvicidal and pupicidal activity was assayed against An. stephensi at various concentrations rangi...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/S1995-7645(13)60003-6
更新日期:2013-02-01 00:00:00
abstract:OBJECTIVE:To identify the chemical constituents and biological activities of essential oil and crude methanol extract of Artemisia vulgaris (A. vulgaris) and Gaultheria fragrantissima (G. fragrantissima). METHODS:Phytochemical screening, total phenolic and flavonoid content, antibacterial activities, anti-oxidant assa...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/j.apjtm.2017.09.005
更新日期:2017-10-01 00:00:00
abstract::Hookworm infection is a relatively common cause of anemia in endemic areas. The most common hookworm species are Ancylostoma duodenale and Necator americanus. In this report we present a case of overt gastrointestinal bleeding because of hookworm infection. Capsule endoscopy revealed many hookworms in the lumen of pro...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/S1995-7645(12)60051-0
更新日期:2012-04-01 00:00:00
abstract:OBJECTIVE:To investigate the therapeutic effect of the intervention treatment with different doses of Captopril on TNF-αcontents in serum of rheumatoid arthritis (RA) rats, and to provide the theoretical proofs for clinical application of Captopril in treatments of rheumatoid diseases. METHODS:Fifty Wistar rats were r...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/S1995-7645(14)60175-9
更新日期:2014-12-01 00:00:00
abstract:OBJECTIVE:To observe preventive and therapeutic effects and the mechanism of actions on Zishen Yutai pill combined with progesterone on threatened abortion in rats. METHODS:After pregnancy, 50 SPF female SD rats were selected and divided into control group, model group, progesterone group, Zishen Yutai pill group, and...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/j.apjtm.2016.04.002
更新日期:2016-06-01 00:00:00
abstract:OBJECTIVE:To explore the effect and mechanism of angiotensin II receptor blockers - Irbesartan on occurrence of ventricular arrhythmias in rats with myocardial ischemia. METHODS:Rats with embryonic cardiomyocytes-H9c2 were randomly divided into control group, ischemia group, Irbesartan group and Irbesartan + ischemia ...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/j.apjtm.2016.07.022
更新日期:2016-10-01 00:00:00
abstract:OBJECTIVE:To investigate capacity of Hyptis suaveolens (H. suaveolens) methanol extract as an antioxidant to protect against carbon tetrachloride (CCl(4))-induced oxidative stress, hepatotoxicity in Albino Wistar rats and cytoprotective effect of hydrogen peroxide (H(2)O(2)) induced cell death in HepG(2) cell line. ME...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/S1995-7645(12)60162-X
更新日期:2012-11-01 00:00:00
abstract::A 19-year-old Asian Indian female presented with productive cough since the past one month and low grade fever since the past two weeks. She was diagnosed with pulmonary tuberculosis and treated with antitubercular drugs. Subsequently, delayed cultures of bronchoalveolar lavage fluid grew Burkholderia pseudomallei (B....
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/S1995-7645(14)60031-6
更新日期:2014-03-01 00:00:00
abstract:OBJECTIVE:To screen the antimicrobial potential of three ethnomedicinal plants Chassalia curviflora Thw. (C. curviflora), Cyclea peltata Hook. F. & Thomson (C. peltata) and Euphorbia hirta L (E. hirta) used in folk medicines in Aarukani hills Kani tribe, Tamil Nadu, India against human bacterial pathogens. METHODS:Ant...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/S1995-7645(11)60107-7
更新日期:2011-05-01 00:00:00
abstract:OBJECTIVE:To determine the effects of environmental parameters of larval habitats on distribution and abundance of anopheline mosquitoes in Rudan county of Iran. METHODS:This cross-sectional study was conducted during the mosquito breeding season from February 2010 to October 2011. The anopheline larvae were collected...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/S1995-7645(13)60087-5
更新日期:2013-07-01 00:00:00
abstract:OBJECTIVE:To determine resistance status of Culex species to different class of insecticides and assess the major anti-mosquito strategies employed by urban households and their possible effects on malaria acquisition. METHODS:Structured questionnaires were randomly administered to obtain information on demographic ch...
journal_title:Asian Pacific journal of tropical medicine
pub_type: 杂志文章
doi:10.1016/S1995-7645(13)60153-4
更新日期:2013-11-01 00:00:00