Overt gastrointestinal bleeding because of hookworm infection.

abstract：OBJECTIVE:To investigate the preventive and therapeutic effect and mechanism of simvastatin on secondary inflammatory damage of rats with cerebral hemorrhage. METHODS:Sixty SD rat aged 9-12 weeks were chosen and divided into the control group, model group and simvastatin-treated group randomly with 20 rats in each gro...

journal_title：Asian Pacific journal of tropical medicine

authors： Zhou HX,Gao LH,Meng LL,Zhang YX,Wei ZF,Si DW

更新日期：2017-02-01 00:00:00

abstract：OBJECTIVE:To describe the epidemiology of snake bite in the region and attempt to compare proven Russell's viper with hump-nosed viper bites. METHODS:All snake bite admissions to the Toxicology Unit of Teaching Hospital Peradeniya over three year from 2006 were included. RESULTS:Of the 776 snakebites, 665(86%) were u...

journal_title：Asian Pacific journal of tropical medicine

authors： Kularatne K,Budagoda S,Maduwage K,Naser K,Kumarasiri R,Kularatne S

更新日期：2011-07-01 00:00:00

abstract：OBJECTIVE:To invest the differences among mesenchymal stem cells (MSCs) derived from different tissues and their impacts on clinical applications. METHODS:In this study, MSCs were isolated from adipose tissue (AD), umbilical cord tissue (UC), and menstrual blood (Men) and compared their biological characteristics in t...

journal_title：Asian Pacific journal of tropical medicine

authors： Chen JY,Mou XZ,Du XC,Xiang C

更新日期：2015-09-01 00:00:00

abstract：OBJECTIVE:To determine the range and incidence of complications associated with Plasmodium vivax (P. vivax) malaria. METHODS:A retrospective analysis was performed of all patients of P. vivax malaria admitted in Kasturba Medical College, Manipal between January and December, 2010. Patients with mixed malarial infectio...

journal_title：Asian Pacific journal of tropical medicine

authors： Naha K,Dasari S,Prabhu M

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:To observe preventive and therapeutic effects and the mechanism of actions on Zishen Yutai pill combined with progesterone on threatened abortion in rats. METHODS:After pregnancy, 50 SPF female SD rats were selected and divided into control group, model group, progesterone group, Zishen Yutai pill group, and...

journal_title：Asian Pacific journal of tropical medicine

authors： Zhang Y,Yan W,Ge PF,Li Y,Ye Q

更新日期：2016-06-01 00:00:00

abstract：OBJECTIVE:To investigate the effects of exogenous recombinant human brain natriuretic peptide (rhBNP) after primary percutaneous coronary intervention (PCI) on non-invasive hemodynamic in acute myocardial infarction patients with left ventricular failure. METHODS:A number of 96 acute myocardial infarction patients acc...

journal_title：Asian Pacific journal of tropical medicine

authors： He XM,Chen L,Luo JB,Feng XX,Zhang YB,Chen QJ,Ji XL,Wang TS

更新日期：2016-08-01 00:00:00

abstract：:The 2014 Ebola outbreak in West Africa, primarily affecting Guinea, Sierra Leone, and Liberia, has exceeded all previous Ebola outbreaks in the number of cases and in international response. Although infections only occur frequently in Western Africa, the virus has the potential to spread globally and is classified as...

journal_title：Asian Pacific journal of tropical medicine

authors： Andreas A,Binoun A Egom C,Kruzliak P,Egom EE

更新日期：2015-10-01 00:00:00

abstract：OBJECTIVE:To explore the regulatory role of thioredoxin-interacting protein (TXNIP) in Wnt/β-catenin signaling pathway and therefore to elucidate its function in diabetic myocardial infarction. METHODS:Diabetic myocardial infarction models were generated in mice. The expression levels of TXNIP and β-catenin and level ...

journal_title：Asian Pacific journal of tropical medicine

authors： Yu H,Zhao XX,Shan XH,Li P,Chen T

更新日期：2015-11-01 00:00:00

abstract：OBJECTIVE:To investigate the differential expression of microRNA (miRNA) in colon between ulcerative colitis (UC) and ulcerative colitis related colorectal cancer (UCRCC). METHODS:An UC mouse model was built by dextran sodium sulfate, and an UCRCC mouse model by dextran sodium sulfate and 1,2-diformylhydrazine. RNAs w...

journal_title：Asian Pacific journal of tropical medicine

authors： Tan YG,Zhang YF,Guo CJ,Yang M,Chen MY

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVE:To elucidates the immunoprophylactic potential of glutathion-s-transferase (GST) from cattle filarial parasite Setaria digitata (S. digitata) against lymphatic filariasis. METHODS:GST was purified through affinity chromatography (SdGST) and chacterized by SDS-PAGE and Nano-LC MS/MS analysis. Antibody isotype...

journal_title：Asian Pacific journal of tropical medicine

authors： Bal M,Mandal N,Achary KG,Das MK,Kar SK

更新日期：2011-03-01 00:00:00

abstract：OBJECTIVE:To discuss the liver function damage mechanism of patients with clonorchiasis by analyzing the ultrasound characteristics, liver function, change of the serum inflammatory factors and cell apoptosis factors. METHODS:Color Doppler ultrasound technique was adopted to detect the portal vein and blood flow chang...

journal_title：Asian Pacific journal of tropical medicine

authors： Fan M,Lu L,Su C,Xue M,Dou JM,Li P,Feng HQ,Fan YB

更新日期：2016-07-01 00:00:00

abstract：OBJECTIVE:To evaluate antioxidant and radical scavenging activities of organic extracts from fruit, roots and aerial parts of Fagonia cretica. METHODS:Shed dried and powdered plant parts were initially extracted in methanol and subsequently partitioned in n-hexane, chloroform, ethyl acetate and 1-butanol successively....

journal_title：Asian Pacific journal of tropical medicine

authors： Iqbal P,Ahmed D,Asghar MN

更新日期：2014-09-01 00:00:00

abstract：OBJECTIVE:To investigate antiviral activity of maca to reduce viral load in Madin-Darby canine kidney (MDCK) cells infected with influenza type A and B viruses (Flu-A and Flu-B, respectively). METHODS:Maca were extracted with methanol (1:2, v/v). The cell viability and toxicity of the extracts were evaluated on MDCK c...

journal_title：Asian Pacific journal of tropical medicine

authors： Del Valle Mendoza J,Pumarola T,Gonzales LA,Del Valle LJ

更新日期：2014-09-01 00:00:00

abstract：OBJECTIVE:To investigate the role of human host heme-oxygenase-1 (HO-1) in pathogenesis of cerebral malaria in the in vitro model. METHODS:The effect of human host HO-1 [human brain microvascular endothelial cell (HBMEC)] on hemoglobin degradation in the co-culture model of HBMEC and ITG Plasmodium falciparum-infected...

journal_title：Asian Pacific journal of tropical medicine

authors： Thongdee P,Na-Bangchang K

更新日期：2017-01-01 00:00:00

abstract：:Harmony is defined as the pleasing combination of elements of a system to form an all-inclusive, all involving and more productive team. The aim of this present review was to investigate the factors militating against harmony among healthcare professional in the Nigerian healthcare delivery system. This review was car...

journal_title：Asian Pacific journal of tropical medicine

authors： Osaro E,Charles AT

更新日期：2014-09-01 00:00:00

abstract：OBJECTIVES:To test the hypothesis that concentration of amniotic fluid alpha-fetal protein (AFAFP) is increased in thalassemia fetus. METHODS:A total of 135 cases of amniocentesis admitted from July 2013 to December 2014 were included in this study. Among them 98 cases of normal fetuses were assigned into control grou...

journal_title：Asian Pacific journal of tropical medicine

authors： Ling Y,Yu YH,Jin S,Hu CX,Peng W,Zhang HY,Fu H,Zhang N,Wei YX

更新日期：2017-02-01 00:00:00

abstract：OBJECTIVE:To determine the phytochemical composition, antioxidant and anticancer activities of ethanolic and water leaves extracts of Annona muricata (A. muricata) from the Eastern Uganda. METHODS:Phytochemical screening was conducted using standard qualitative methods and a Chi-square goodness of fit test was used to...

journal_title：Asian Pacific journal of tropical medicine

authors： Gavamukulya Y,Abou-Elella F,Wamunyokoli F,AEl-Shemy H

更新日期：2014-09-01 00:00:00

abstract：:A natural prodrug is a chemical compound or substance obtained from plants, microorganism, animal and marine sources. Natural products are small molecule source for Food and Drug Administration approved drugs and major sources for drug discovery. Most of the drugs for different ailment diseases undergo first pass meta...

journal_title：Asian Pacific journal of tropical medicine

authors： Kumar SV,Saravanan D,Kumar B,Jayakumar A

更新日期：2014-09-01 00:00:00

abstract：OBJECTIVE:To report presence of Leishmania major in Khyber Pakhtunkhwa of Pakistan, where cutaneous leishmaniasis (CL) is endemic and was thought to be caused by Leishmania tropica only. METHODS:Biopsy samples from 432 CL suspected patients were collected from 3 southern districts of Khyber Pakhtunkhwa during years 20...

journal_title：Asian Pacific journal of tropical medicine

authors： Hussain M,Munir S,Ayaz S,Khattak BU,Khan TA,Muhammad N,Anees M,Rahman H,Qasim M,Jamal MA,Ahmed I,Rahim K,Mazhar H,Watanay N,Kasbari M

更新日期：2017-07-01 00:00:00

abstract：OBJECTIVE:To build the rat model of gastric precancerous lesions and discuss the effect of transplantation of mesenchymal stem cells (BMMSCs) on the pathological change. METHODS:The rat model of gastric precancerous lesions was built using N-methyl-N'-nitro-N'-nitrosoguanidine. After the intravenous transplantation of...

journal_title：Asian Pacific journal of tropical medicine

authors： Lin ZL,Zheng GW,Zhang L,Zheng JT,Chen H

更新日期：2015-12-01 00:00:00

abstract：OBJECTIVE:To investigate capacity of Hyptis suaveolens (H. suaveolens) methanol extract as an antioxidant to protect against carbon tetrachloride (CCl(4))-induced oxidative stress, hepatotoxicity in Albino Wistar rats and cytoprotective effect of hydrogen peroxide (H(2)O(2)) induced cell death in HepG(2) cell line. ME...

journal_title：Asian Pacific journal of tropical medicine

authors： Ghaffari H,Ghassam BJ,Prakash HS

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVE:To investigate the hepatoprotective and antioxidant activities of Alchornea cordifolia (A. cordifolia) leaf extract. METHODS:Various solvent fractions of the methanol extract of the leaf of the plant A. cordifolia Mull. Arg (Fam: Euphorbiaceae) were evaluated for hepatoprotective activity by carbon tetrachlo...

journal_title：Asian Pacific journal of tropical medicine

authors： Osadebe PO,Okoye FB,Uzor PF,Nnamani NR,Adiele IE,Obiano NC

更新日期：2012-04-01 00:00:00

abstract：OBJECTIVE:To explore the value of B-ultrasound on the evaluation of the effects of traditional Chinese medicine compound of Radix astragali, Salvia miltiorrhiza and Angelica sinensis, and TCM + praziquantel on liver fibrosis in rabbits with schistosomiasis. METHODS:The hepatic fibrosis model in rabbits with schistosom...

journal_title：Asian Pacific journal of tropical medicine

authors： Liang XL,Yuan JY

更新日期：2013-08-01 00:00:00

abstract：:We report two cases of pulmonary sequestration infected with nontuberculous mycobacteria (NTM): Mycobacterium avium and Mycobacterium abscessus. Chest computed tomography showed pneumonic consolidation in the right lower lobe, which received a systemic blood supply from the descending aorta in both patients. Video-ass...

journal_title：Asian Pacific journal of tropical medicine

authors： Koh WJ,Hong G,Kim K,Ahn S,Han J

更新日期：2012-11-01 00:00:00

abstract：:Tuberculosis (TB) is a symbolic menace to mankind, infecting almost one third of the world's populace and causing over a million mortalities annually. Mycobacterium tuberculosis (Mtb) is the key pathogen of TB that invades and replicates inside the host's macrophage. With the emerging dilemma of multi-drug resistant t...

journal_title：Asian Pacific journal of tropical medicine

authors： Khusro A,Aarti C,Agastian P

更新日期：2016-11-01 00:00:00

abstract：:Brucellosis is a zoonotic disease characterized by reproductive failure in animals and undulent fever in humans. In cattle, it is caused by Brucella abortus while in goats by Brucella melitensis, the main cause of brucellosis in humans. Brucellosis in livestock has been associated with importation of animals from bree...

journal_title：Asian Pacific journal of tropical medicine

authors： Zamri-Saad M,Kamarudin MI

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVE:To estimate the genetic diversity of Kokobera virus, the date of origin and the spread among different viruses in the endemic regions of Australia. METHODS:Two datasets were built. The first consisting of 29 sequences of the NS5/3' UTR region of Kokobera group downloaded from GenBank, the second including on...

journal_title：Asian Pacific journal of tropical medicine

authors： Blasi A,Lo Presti A,Cella E,Angeletti S,Ciccozzi M

更新日期：2016-10-01 00:00:00

abstract：:This paper reviews the existing depth of anaesthesia (DoA) monitors and their algorithms and also proposes to improve their performance from four aspects. An ideal DoA monitor should be able to suggest a personalised drug dosage, to predict and provide early warnings when dosages are inappropriate, to be portable and ...

journal_title：Asian Pacific journal of tropical medicine

authors： Li TN,Li Y

更新日期：2014-06-01 00:00:00

abstract：OBJECTIVE:To investigate the efficiency of β-galactosidase gene transfer into rat kidney with ultrasound-mediated microbubble destruction via different injection routes. METHODS:A total of 25 Wistar rats were randomly divided into 5 groups. Four groups received a mixture of optison microbubbles (0.2 mL) and lacz plasm...

journal_title：Asian Pacific journal of tropical medicine

authors： Chen JX,Ma Q,Wu H,Zhou A,Chen X,Peng YM,Liu FY,Cheng MC

更新日期：2012-07-01 00:00:00

abstract：OBJECTIVE:To explore the regulation effect of Rheum palmatum (R. palmatum) L. on NF-κB signaling pathway of ALF mice. METHODS:The intraperitoneal injection of d-GalN/LPS was employed for the model building. Mice in the treatment group and positive control group were given the R. palmatum L. and bifendate before the mo...

journal_title：Asian Pacific journal of tropical medicine

authors： Zhang RZ,Qiu H,Wang N,Long FL,Mao DW

更新日期：2015-10-01 00:00:00