Bone morphogenetic protein and orthopaedic surgery: can we legitimate its off-label use?

abstract：:Bony defects caused by trauma, tumors, infection or congenital anomalies can present a significant surgical challenge. Free vascularised fibular bone grafts (FVFGs) have proven to be extremely effective in managing larger defects (longer than 6 cm) where other conventional grafts have failed. FVFGs also have a role in...

journal_title：International orthopaedics

authors： Bumbasirevic M,Stevanovic M,Bumbasirevic V,Lesic A,Atkinson HD

更新日期：2014-06-01 00:00:00

abstract：PURPOSE:The aim of the study was to investigate risk factors for metastasis at diagnosis. METHODS:We collected patients diagnosed with conventional chondrosarcoma between 1983 and 2014 from the Surveillance, Epidemiology, and End Results (SEER) database. Each patient was classified as having metastatic or localized di...

journal_title：International orthopaedics

authors： Song K,Shi X,Liang X,Wang H,Zou F,Lu F,Ma X,Jiang J

更新日期：2018-12-01 00:00:00

abstract：:The authors report seven cases of desmoid tumors of the extremities. A tumour less than a few centimetres in size is best removed by wide local excision. Large growths should also be excised, but efforts should be made to preserve the vessels and nerves, since malignant transformation and metastases do not occur. Irra...

journal_title：International orthopaedics

authors： Vizkelety T,Szendröi M

更新日期：1988-01-01 00:00:00

abstract：PURPOSE:The anterior cruciate ligament (ACL) is known to have a poor healing ability, especially in comparison with the medial collateral ligament (MCL) which can heal relatively well. Interleukin-1beta (IL-1β) is considered to be an important chemical mediator in the acute inflammatory phase of ligament injury. The ro...

journal_title：International orthopaedics

authors： Xie J,Wang C,Yin L,Xu C,Zhang Y,Sung KL

更新日期：2013-03-01 00:00:00

abstract：:In achondroplasts limb lengthening can restore the normal proportion of the body. The Ilizarov method of limb lengthening has been used in 37 patients, 23 of whom have had an adequate follow-up after operation. In this technique the cortex of the bone is partially cut, leaving the medulla intact; the two bone segments...

journal_title：International orthopaedics

authors： Cattaneo R,Villa A,Catagni M,Tentori L

更新日期：1988-01-01 00:00:00

abstract：INTRODUCTION:Dual-mobility cups (DMC) are gaining popularity mainly for their reduced rate of dislocation following total hip arthroplasty (THA). Currently, indication for DMC use extends beyond patients with high risk of dislocation or revision THA cases. Many authors reported DMC outcomes in primary THA for all aetio...

journal_title：International orthopaedics

authors： Assi C,Mansour J,Prudhon JL,Caton J,Yammine K

更新日期：2020-09-19 00:00:00

abstract：:A description is given of the vertical and horizontal components of the forces applied to the floor by the foot in walking. Information about the characteristics of the normal force pattern was obtained from the analysis of the gait of 214 normal subjects (108 young adults, 63 elderly people and 43 children). It is su...

journal_title：International orthopaedics

authors： Claeys R

更新日期：1983-01-01 00:00:00

abstract：:Subluxation of the patella may produce pain and instability in young people. However its classification, diagnosis and treatment are controversial. We have used computerized tomography (CT) to measure the amount of lateral shift of the patella and the angle of tilt to the femur in patients with subluxation. The mean l...

journal_title：International orthopaedics

authors： Sasaki T,Yagi T

更新日期：1986-06-01 00:00:00

abstract：:An osteosarcoma developed in a boy, 16 years of age, 9 years after staples had been inserted in the region of the lower femoral epiphysis. The possible association between the implant and the tumour is discussed. ...

journal_title：International orthopaedics

authors： Kumar K

更新日期：1996-01-01 00:00:00

abstract：PURPOSE:The purpose of this study was to show that this two-stage procedure for ACL (anterior cruciate ligament) revision surgery could be straight-forward and provide satisfactory clinical and functional outcomes. MATERIALS:This is a five-year prospective analysis of clinical and functional data on 30 patients (19 me...

journal_title：International orthopaedics

authors： Franceschi F,Papalia R,Del Buono A,Zampogna B,Diaz Balzani L,Maffulli N,Denaro V

更新日期：2013-07-01 00:00:00

abstract：PURPOSE:The purpose of this study was to quantify limitations in sagittal ankle range of motion (ROM) at least two years after lateral column lengthening osteotomy of the calcaneus (LLC) and their implications regarding quality of life. METHODS:Fifteen patients with a mean follow-up of 80 ± 27 months after LLC and 15 ...

journal_title：International orthopaedics

authors： Nüesch C,Schmid AK,Byrnes SK,Krenn P,Horisberger M,Mündermann A,Leumann A

更新日期：2020-06-01 00:00:00

abstract：PURPOSE:Our aim was to explore the effect of varying in vitro culture conditions on general chondrogenesis of minced cartilage (MC) fragments. METHODS:Minced, fibrin-associated, bovine articular cartilage fragments were cultured in vitro within polyurethane scaffold rings. Constructs were maintained either free swelli...

journal_title：International orthopaedics

authors： Wang N,Grad S,Stoddart MJ,Niemeyer P,Reising K,Schmal H,Südkamp NP,Alini M,Salzmann GM

更新日期：2014-05-01 00:00:00

abstract：INTRODUCTION:The aim of this study was to determine whether an above-elbow cast (AEC) is better than a below-elbow cast (BEC) at maintaining the initial reduction in the orthopaedic management of a distal radius fracture (DRF). METHODS:It is a prospective randomized study carried out in a single emergency trauma depar...

journal_title：International orthopaedics

authors： Gamba C,Fernandez FAM,Llavall MC,Diez XL,Perez FS

更新日期：2017-09-01 00:00:00

abstract：:Acetabular retroversion may contribute to femoroacetabular impingement and lead to osteoarthritis of the hip. Retroversion has been measured on computed tomography scans. In recent years, assessment of acetabular version on anteroposterior pelvic views has gained increasing attention. We therefore aimed to determine t...

journal_title：International orthopaedics

authors： Kappe T,Kocak T,Neuerburg C,Lippacher S,Bieger R,Reichel H

更新日期：2011-06-01 00:00:00

abstract：:This study evaluates the role of arthroscopy in the diagnosis of acute injuries to the knee. One hundred and fifty four patients with a suspected ligament injury or effusion of the knee joint underwent arthroscopy. A haemarthrosis was present in 82% and a bloodless effusion in 10%. Meniscal tears were found in 19% of ...

journal_title：International orthopaedics

authors： Johannsen HV,Fruensgaard S

更新日期：1988-01-01 00:00:00

abstract：PURPOSE:Intramedullary screw fixation is currently considered the gold standard treatment for Jones fractures in the athlete. Besides biological factors (i.e., poor vascularization), mechanical instability induced by the pull of the peroneus brevis tendon (PBT) contributes to deficient Jones fracture healing. This biom...

journal_title：International orthopaedics

authors： Willegger M,Benca E,Hirtler L,Moser L,Zandieh S,Windhager R,Schuh R

更新日期：2020-07-01 00:00:00

abstract：PURPOSE:For complex proximal humeral fractures, severe displacement and comminuted fragments lead to poor clinical outcomes. Despite considerable management, the locking plate fixation is still a preference and the proper selection of its strategy for each individual seems to be essential. METHOD:The available classif...

journal_title：International orthopaedics

authors： Sun Q,Wu X,Wang L,Cai M

更新日期：2020-09-01 00:00:00

abstract：:A seven-year-old girl, whose right knee gave way, was found to have anterolateral instability of the joint associated with congenital aplasia of the anterior cruciate ligament. Instability was present in the final 30 degrees of extension, and has been controlled by a brace which prevented this movement. ...

journal_title：International orthopaedics

authors： Hejgaard N,Kjaerulff H

更新日期：1987-01-01 00:00:00

abstract：PURPOSE:We will test the hypothesis that ultrasound supported by polymerase chain reaction (PCR) could improve bacterial identification in non-infected prosthetic joint loosening. The aim was to detect bacterial species in non-infected prosthetic joint loosening using ultrasound and 16S rRNA gene sequencing. METHODS:A...

journal_title：International orthopaedics

authors： Bereza PL,Ekiel A,Auguściak-Duma A,Aptekorz M,Wilk I,Kusz DJ,Wojciechowski P,Martirosian G

更新日期：2013-10-01 00:00:00

abstract：:Fractures around a femoral prosthesis have been treated with plating and additional cement, but this leads to further reduction of bone stock in the proximal femur. Since February 1992, we have dealt with this problem in 12 patients by revision using a long uncemented stem and distal interlocking combined with homolog...

journal_title：International orthopaedics

authors： Eingartner C,Volkmann R,Pütz M,Weller S

更新日期：1997-01-01 00:00:00

abstract：:Postoperative infection is a regular complication in coccygectomy. The authors propose the use of a topical skin adhesive on the postoperative wound as a contribution to the prevention of this complication. It was used on the first 56 patients in this study. The rate of infection was 3.6% compared with the 14% rate of...

journal_title：International orthopaedics

authors： Doursounian L,Maigne JY,Cherrier B,Pacanowski J

更新日期：2011-06-01 00:00:00

abstract：:There is no evidence surrounding the benefits, effects or clinical outcomes treating asymptomatic urinary tract colonisation. A series of 558 patients undergoing elective admission for orthopaedic surgery were recruited prior to surgery and were screened for urinary tract infection (UTI). Patients had their urine dips...

journal_title：International orthopaedics

authors： Ollivere BJ,Ellahee N,Logan K,Miller-Jones JC,Allen PW

更新日期：2009-06-01 00:00:00

abstract：:We evaluated the results of polygonal triple (Kotz) osteotomy for the treatment of acetabular dysplasia over 10 years. This study included 31 hips of 27 patients who had the Kotz osteotomy for acetabular dysplasia. The mean age was 21.5 years. We performed the original Kotz osteotomy for the first 22 hips (group I), w...

journal_title：International orthopaedics

authors： Sen C,Gunes T,Erdem M,Ozger H,Tozun IR

更新日期：2007-06-01 00:00:00

abstract：PURPOSE:Hip-joint empyema is a severe local infection that can cause general illness and, in the worst-case scenario, death by septic complications. For severe hip-joint infections, the Girdlestone arthroplasty has been an established treatment option for many decades. We describe functional midterm results after treat...

journal_title：International orthopaedics

authors： Oheim R,Gille J,Schoop R,Mägerlein S,Grimme CH,Jürgens C,Gerlach UJ

更新日期：2012-05-01 00:00:00

abstract：PURPOSE:Dislocations of components, loosening of the stem, overstuffing and removal in up to 24 % of common radial head prostheses (RHP) after implantation in complex elbow injuries signal the need for improvement. The latest biomechanical evidence shows advantages for monopolar designs. Clinical results after primary ...

journal_title：International orthopaedics

authors： Katthagen JC,Jensen G,Lill H,Voigt C

更新日期：2013-04-01 00:00:00

abstract：PURPOSE:Patient-specific instrumentation (PSI) was usually applied in total knee arthroplasty (TKA) to acquire a favourable alignment. We hypothesized that using PSI had a potential risk of notching in the anterior femoral cortex, because the femoral component may be placed in an overextension position due to the dista...

journal_title：International orthopaedics

authors： Ke S,Ran T,He Y,Lv M,Song X,Zhou Y,Xu Y,Wang M

更新日期：2020-12-01 00:00:00

abstract：:Osteosarcoma, the most common type of primary malignant tumour that develops in bone, can be classified into several different sub-types. While the majority of osteosarcomas are highly malignant, there are some low-grade variants. Since the introduction of chemotherapy into the multi-modal treatment regimen of high-gr...

journal_title：International orthopaedics

authors： Carrle D,Bielack SS

更新日期：2006-12-01 00:00:00

abstract：:We have undertaken a meta-analysis of the English literature, to assess the component alignment outcomes after imageless computer assisted (CAOS) total knee arthroplasty (TKA) versus conventional TKA. We reviewed 23 publications that met the inclusion criteria. Results were summarised via a Bayesian hierarchical rando...

journal_title：International orthopaedics

authors： Brin YS,Nikolaou VS,Joseph L,Zukor DJ,Antoniou J

更新日期：2011-03-01 00:00:00

abstract：PURPOSE:Forty patients were enrolled in a prospective randomised study using conventional method or "Trabecular Metal Cone" (TM Cone) (Zimmer inc., Warsaw, USA) for reconstruction of bone loss of the proximal tibia during revision total knee arthroplasty (rTKA). The aim was to evaluate changes in bone mineral density (...

journal_title：International orthopaedics

authors： Jensen CL,Petersen MM,Schrøder HM,Lund B

更新日期：2012-09-01 00:00:00

abstract：INTRODUCTION:Lateral humeral condylar fractures are the second most common elbow fractures in children. We present the long-term clinical and radiographic results. MATERIAL AND METHODS:All children (<16 years) in the geographic catchment area with lateral condylar fracture were asked to participate and 32 (76.2%) pati...

journal_title：International orthopaedics

authors： Sinikumpu JJ,Pokka T,Victorzon S,Lindholm EL,Serlo W

更新日期：2017-07-01 00:00:00