Abstract：
BACKGROUND:A drug-related problem (DRP) may be defined as "an event or circumstance involving drug therapy that actually or potentially interferes with the desired health outcome". Our aim was to determine the frequency and characteristics of DRPs in pediatric patients admitted to a tertiary cardiac care center in the Egyptian capital, Cairo. METHODS:A prospective observational cohort study involving review of case notes for children aged 0-18 years, admitted to the medical ward and intensive care unit (ICU), was conducted at a tertiary cardiac care center in Egypt. Data collection took place over a three-month period. Daily reviews of patients' records, medication charts and laboratory data were undertaken by the clinical pharmacists to identify DRPs. RESULTS:A total of 60 patients were included in the study (mean age 4.8 years; 53.33% males). Over a three-month period, a total of 313 DRPs were recorded corresponding to an average of 5.22 problems per patient. The most commonly recorded problems related to drug-drug interaction (45.69%), prescribing unnecessary medication (31.95%), under-dosing (21.09%), inappropriate medication (0.96%) and adverse drug reaction (0.32%). Prophylactic antibiotics represented the only unnecessarily prescribed medications. Of the pharmacist suggested interventions, 65% were accepted by the responsible physician. CONCLUSIONS:DRPs occurred frequently during the study period. Drug-drug interactions, drug choice and drug dosing problems represented the majority of the identified DRPs, necessitating targeted prescriber education interventions in these areas. There is a clear need for clinical pharmacists' involvement on the ward level to identify and rectify these frequently occurring and very costly problems.
journal_name
Minerva Pediatrjournal_title
Minerva pediatricaauthors
Sabry N,Farid S,Dawoud Dsubject
Has Abstractpub_date
2016-04-01 00:00:00pages
89-95issue
2eissn
0026-4946issn
1827-1715pii
R15Y9999N00A140016journal_volume
68pub_type
杂志文章abstract：:The Authors describe a case report of a girl of 7 years affected by visceral leishmaniasis (VL) complicated by herpes zoster (Hz). Hz infection is unusual in paediatric age, but it may complicate immunodeficiency states. VL causes, as well known, T cell immunity depression: Hz infection could be facilitated by this si...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
abstract：BACKGROUND:To document the evolution of cranial asymmetries in infants with signs of nonsynostotic occipital plagiocephaly (NSOP) who were undergo to many functional manual therapy treatments (in addition to the standard positioning recommendations) as well as to determine the feasibility of this methodology to conduct...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：10.23736/S0026-4946.17.04838-1
更新日期：2017-10-25 00:00:00
abstract：AIM:The objective of this paper is an empirical analysis of mother-infant feeding interactions through an observational instrument (Feeding Scale), which is applied to the videotape of a feeding session. METHODS:Three samples of mothers and their children have been examined (104 couples with children ranging in age fr...
journal_title：Minerva pediatrica
pub_type： 杂志文章,评审
doi：
更新日期：2003-06-01 00:00:00
abstract：BACKGROUND:To investigate if high dose inhaled beclomethasone dipropionate started early after upper respiratory tract infection (URTI) could reduce recurrent wheezing in infants. METHODS:Twenty-six ambulatory infants, 7-12 months of age, with recurrent wheezing during upper respiratory tract infection participated. A...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2002-06-01 00:00:00
abstract：AIM:Promoting physical activity is one of the main goals of health-promotion policies. The period of adolescence is characterised by a high rate of abandonment of any physical activity. In this age range, moreover, the risk of assuming substances in order to improve muscular-mass or athletic results is concrete. This s...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2004-06-01 00:00:00
abstract：BACKGROUND:Although the main treatments of inflammatory bowel disease (IBD) aim at the induction and maintenance of clinical remission, several studies have demonstrated inflammation still present in clinical remission. The goal of this study was to analyze the gene expression profiles between the pediatric IBD and con...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：10.23736/S0026-4946.18.04997-6
更新日期：2018-01-29 00:00:00
abstract：AIM:The increase in life expectancy of cystic fibrosis (CF) patients has brought about a rise in new clinical problems in these patients, such as a decrease in bone mineral density (BMD). The cause of diminished BMD in CF is multi-factorial. METHODS:The aim of this cross-sectional study, conducted on 39 CF patients un...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2008-04-01 00:00:00
abstract：:This study evaluates the importance of magnetic resonance imaging (MR) in the exploration of the abdomen in a case of non-Hodgkin lymphoma diagnosed in a 14-year-old boy. Results are compared with those obtained using two widely used diagnostic methods: CT and ultrasonography (US). US revealed a prevalent involvement ...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：1991-04-01 00:00:00
abstract：BACKGROUND:Recently it is often very frequent a request of specialist consultation for children with psychic discomfort expressed through somatic complaints and/or behavior disorders. The real meaning of these symptoms in terms of prognosis, is not clear; indeed they can be the first signs of a poor prognosis of develo...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：1998-09-01 00:00:00
abstract：:Congenital dermal sinus represents a dysraphic state of the central nervous system. It can show up throughout a defect of the midline, of both the skull and the spine. Usually, the malformation presents a fistulous tract, connecting the skin with the underlying tissues (hypoderm, paraspinal muscles, vertebrae and, in ...
journal_title：Minerva pediatrica
pub_type： 杂志文章,评审
doi：
更新日期：1990-12-01 00:00:00
abstract：:A study was carried out to characterize in the growing skeleton the absorptiometric measurement of the ultradistal radial epiphysis where the trabecular bone is higher than at proximal scanning planes. The study showed that a radius scan, 1 to 1.4 cm proximal to the ulnar tip, and consequently 4 to 6 mm proximal to th...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：1991-07-01 00:00:00
abstract：:Providing optimal mechanical ventilation to critically-ill children remains a challenge. Patient-ventilator dyssynchrony results frequently with numerous deleterious consequences on patient outcome including increased requirement for sedation, prolonged duration of ventilation, and greater imposed work of breathing. M...
journal_title：Minerva pediatrica
pub_type： 杂志文章,评审
doi：
更新日期：2016-12-01 00:00:00
abstract：:Chronic viral hepatitis B and C infections are highly prevalent and create a substantial burden to healthcare systems globally. These two chronic infections are the cause of significant global morbidity and mortality with approximately 1 million annual deaths attributable to them and their sequelae. Children are vulne...
journal_title：Minerva pediatrica
pub_type： 杂志文章,评审
doi：
更新日期：2014-10-01 00:00:00
abstract：:More than one million neonatal deaths every year in the world are attributable to infection. In nurseries, infections occur with a reported incidence of 0.3-3%; in Neonatal Intensive Care Units (NICUs) the reported incidence is 7-24.5%, and up to 40% in newborns with birth weight less than 1000 g or gestational age at...
journal_title：Minerva pediatrica
pub_type： 杂志文章,评审
doi：
更新日期：2013-02-01 00:00:00
abstract：BACKGROUND:COVID-19 has quickly become a worldwide threat to health, travel, and commerce. Studies adressing the clinical-functional presentation of viral infection and physiotherapy management in children are scarce. The purpose statement was to provide current perspectives on the physiotherapy interventions for manag...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：10.23736/S0026-4946.20.06100-9
更新日期：2020-10-27 00:00:00
abstract：AIM:To evaluate the trend of infantile obesity in the school-aged population of Cremona over time. METHODS:The weight and height of all children aged 6, 9 and 11 attending schools within the health district of Cremona were measured for 9 consecutive years (January 1990-March 1998), giving a total of 17,730 measurement...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2000-01-01 00:00:00
abstract：:The authors report the case of a 13-year-old girl affected with urethritis, conjunctivitis, and oligoarticular arthritis. These symptoms represent the classical triad of Fiessinger-Leroy-Reiter's syndrome. The research for HIV was negative and the antigen HLA B27 was absent. The young patients has been treated by FANS...
journal_title：Minerva pediatrica
pub_type： 杂志文章,评审
doi：
更新日期：1993-07-01 00:00:00
abstract：AIM:Considering how eating habits affect the health of children and taking into account the influence of advertising messages, we wanted to investigate the quantity and the typology of advertising on air during children's television programmes. METHODS:The research was conducted beginning in January 2008 up to March 2...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2012-02-01 00:00:00
abstract：:Insulin-dependent diabetes mellitus is associated to important micro and macro vascular complications. A good metabolic control can reduce the risk of complications. Aim of the study was to evaluate the metabolic control in adolescent diabetic patients using an educational system with graphic visualisation of capillar...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：1996-06-01 00:00:00
abstract：:The diagnosis of gastroesophageal reflux disease (GERD) has evolved from reliance on history and fluoroscopy to continuous esophageal pH monitoring with catheter-based pH probes and wireless pH probes to continuous impedance/pH monitoring. This review describes the currently employed diagnostic tests and the actual ma...
journal_title：Minerva pediatrica
pub_type： 杂志文章,评审
doi：
更新日期：2012-12-01 00:00:00
abstract：INTRODUCTION:Chronic rhinosinusitis (CRS) is defined as an inflammatory disorder of the paranasal sinuses and of the nasal mucosa that lasts 12 weeks or longer. In CRS microbes contribute to the disease pathogenesis. Clinical microbiology is focused on finding single pathogens that causes the disease and the main goal ...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：10.23736/S0026-4946.20.05850-8
更新日期：2020-07-29 00:00:00
abstract：AIM:Recently, it was reported that the development of breast tissue and secondary sex characteristics in girls occurred at much younger age and the incidences of premature thelarce (PT) and central idiopathic precocious puberty (ICPP) are increasing. In this context, we wanted to evaluate the mycoestrogen exposure as t...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2014-12-01 00:00:00
abstract：BACKGROUND:The aim of this study was to analyze multidrug resistance-associated protein 1 (MRP1) expression of peripheral blood of children intractable epilepsy. METHODS:Sixty children with epilepsy admitted to outpatient and inpatient services of Xuzhou Children's Hospital between November 2010 and October 2011 were ...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：10.23736/S0026-4946.16.04358-9
更新日期：2018-04-01 00:00:00
abstract：BACKGROUND:Glioma is the most common extracranial solid tumor of children. The malignant (cancer) cells form in neural crest cell of the adrenal gland. In this study we investigate the expressions of Myogenin and OCT4 in Glioma which might be used as prognostic makers for this deteriorated disease. METHODS:We used Qua...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：10.23736/S0026-4946.18.05396-3
更新日期：2018-12-03 00:00:00
abstract：AIM:Glioneuronal tumors (especially gangliogliomas and dysembryoplastic neuroepithelial tumors) are an increasingly recognised cause of drug-resistant epilepsy in children. The optimal surgical strategy (lesionectomy vs. extended resection of epileptogenic peritumoral areas) to obtain seizure control has not been fully...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2013-12-01 00:00:00
abstract：:Noonan syndrome (NS) is a rare genetic disorder, revealing autosomal dominant trait. It is a multiface condition that is characterized by a series congenital malformations including facial anomalies, postnatal growth retardation, webbing of the neck, pectus excavatum/carinatum, pulmonic stenosis and undescended testic...
journal_title：Minerva pediatrica
pub_type： 杂志文章,评审
doi：
更新日期：2008-06-01 00:00:00
abstract：:GER is the passage of gastric contents into the esophagus and is referred to as GER disease (GERD) when GER causes troublesome symptoms and/or complications. GERD in infants and children is sometimes difficult to diagnose and even more difficult to treat. The diagnosis of GERD is hampered by the fact that GER symptoms...
journal_title：Minerva pediatrica
pub_type： 杂志文章,评审
doi：
更新日期：2012-02-01 00:00:00
abstract：:Salmonella infections can manifest themselves as acute abdominal problems and lead to emergency surgery. Some examples are: salmonella-related intestinal perforations, gallbladder involments, salpingitis, and peritonitis. Mesenteric lymphadenitis associated with salmonella mimics acute appendicitis and it is often dif...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2006-04-01 00:00:00
abstract：:Non-alcoholic fatty liver disease (NAFLD) encompasses a range of liver histology severity and outcomes in the absence of chronic alcohol use. The mildest form is simple steatosis in which triglycerides accumulate within hepatocytes. A more advanced form of NAFLD, non-alcoholic steatohepatitis (NASH), includes inflamma...
journal_title：Minerva pediatrica
pub_type： 杂志文章,评审
doi：
更新日期：2010-12-01 00:00:00
abstract：INTRODUCTION:Online grooming is an active communicative entrapment network involving a wide range of techniques. The interactions that groomers have with minors online are complex. The purpose of the present literature review is to contribute to the existing knowledge base regarding online sex offender typologies, pred...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：10.23736/S0026-4946.20.05621-2
更新日期：2020-05-15 00:00:00
