Abstract：
:GER is the passage of gastric contents into the esophagus and is referred to as GER disease (GERD) when GER causes troublesome symptoms and/or complications. GERD in infants and children is sometimes difficult to diagnose and even more difficult to treat. The diagnosis of GERD is hampered by the fact that GER symptoms such as irritability and crying, feed refusal and regurgitation are common problems in infants and these symptoms are not specific for GERD. Diagnostic criteria for the objective diagnosis of GERD with commonly used diagnostic tests such as pH-metry, pH-impedance monitoring and endoscopy are poorly or not defined. In this review the current understanding of (patho)physiology of GERD, clinical history in infants and children, new insights in diagnostic modalities and the role of non-pharmacological and pharmacological interventions are discussed.
journal_name
Minerva Pediatrjournal_title
Minerva pediatricaauthors
Loots CM,Benninga MA,Omari TIsubject
Has Abstractpub_date
2012-02-01 00:00:00pages
101-19issue
1eissn
0026-4946issn
1827-1715pii
R15123747journal_volume
64pub_type
杂志文章,评审abstract：:Age of diagnosis and clinical pattern were studied in 97 celiac patients, diagnosed with jejunal biopsy, between 1976-1991. They were selected on the basis of clinical and laboratory patterns. The laboratory tests utilized were steatorrhea and xylose in the first years, while in recent years AGA, ARA and AEA were also...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：1996-09-01 00:00:00
abstract：BACKGROUND AND AIMS:The hypothesis of an emotional component in asthma has been put forward since antiquity. It is currently explored using a psychodynamic, cognitive-behavioural and systemic-relational approach. This study, carried out using a psychodynamic approach, aimed to identify the psychological aspects of recu...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：1998-03-01 00:00:00
abstract：:Congenital diaphragmatic hernia (CDH) remains one of the major challenges in neonatal surgery. Survival rate has increased in the last decades mainly due to perinatal care and surgical technique improvements. Classically, a laparotomy has been performed after cardiovascular and respiratory stabilization. Introduction ...
journal_title：Minerva pediatrica
pub_type： 杂志文章,评审
doi：10.23736/S0026-4946.17.05110-6
更新日期：2018-06-01 00:00:00
abstract：:More than one million neonatal deaths every year in the world are attributable to infection. In nurseries, infections occur with a reported incidence of 0.3-3%; in Neonatal Intensive Care Units (NICUs) the reported incidence is 7-24.5%, and up to 40% in newborns with birth weight less than 1000 g or gestational age at...
journal_title：Minerva pediatrica
pub_type： 杂志文章,评审
doi：
更新日期：2013-02-01 00:00:00
abstract：:This is the first scientific study on Mary Sandrucci, who has been director of the Pediatric Clinic of the University of Turin from 1965-1966 up to 31 December 1989. Prof. Sandrucci led major studies on congenital heart disease, was the first Italian and among the first in Europe to describe phocomelia cases, to repor...
journal_title：Minerva pediatrica
pub_type： 传,历史文章,杂志文章
doi：
更新日期：2011-04-01 00:00:00
abstract：:Celiac disease (CD) is one of the most common immune-mediated diseases with a worldwide prevalence of around 1%, although a couple of decades ago the disease was thought to be very rare. CD is characterized by an inadequate inflammatory response to gluten in genetically susceptible individuals. In this inflammatory re...
journal_title：Minerva pediatrica
pub_type： 杂志文章,评审
doi：
更新日期：2012-06-01 00:00:00
abstract：:Megapolycalicosis is defined as a congenital dilatation of calices without evidence of obstruction. In absence of complications such as infection and stones, megapolycalicosis would not have a particular clinical relevance if not for the possible misinterpretation as hydronephrosis. A case of megapolycalicosis is pres...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：1994-05-01 00:00:00
abstract：:Biliary atresia is a severe neonatal malformation in which the entire extrahepatic biliary tract or part of it is absent and replaced by fibrosclerotic tissue. Having been described for the first time by Thomson in 1891, biliary atresia has an incidence of 1:10,000-15,000 live neonates with a slight predominance in th...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2001-08-01 00:00:00
abstract：BACKGROUND:In this paper we present growth height standards obtained by an auxological study on a primary school population of central Italy (Lazio), in the 1991-1992 and 1992-1993 school-years. METHODS:4,175 children were included in the study: 2,024 females and 2,151 males, aged from 6 to 11 years. The sampling rate...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：1997-04-01 00:00:00
abstract：:A survey was carried out within the framework of the Association of Hospital Pediatricians (APO) on the implementation of the pediatric structure in Pediatric hospitals wards in Piedmont during 1990. There was a 100% adhesion rate. It was found that only in 7 out of 36 hospitals were children always admitted to the Pe...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：1996-09-01 00:00:00
abstract：AIM:The estimation of peak expiratory flow (PEF) in children is a very easy and practical way to check lung function and helps in the diagnosis, treatment follow-up and evaluation of the development of chronic obstructive pulmonary disease. METHODS:Using a Mini-Wright flowmeter (Clement Clarke International Ltd, Engla...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2005-04-01 00:00:00
abstract：:During patient triggered ventilation, the infant's inspiratory efforts should occur synchronously with ventilator inflations. Such an optimal interaction, however, is dependent on the performance of the triggering device and the ventilator and the infant's lung function. Triggered ventilation (assist control, A/C), sy...
journal_title：Minerva pediatrica
pub_type： 杂志文章,评审
doi：
更新日期：2006-08-01 00:00:00
abstract：BACKGROUND:Aim of study was to ascertain the possible presence of congenital dysplasia of the hip in infants (CDH) in the population immigrated from countries where the problem is surely neglected from the local health service and estimate its incidence. Moreover to observe the impact of the CDH problem on the parents ...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：1997-10-01 00:00:00
abstract：:The majority of childhood cancer patients can expect nowadays to be cured and the percentage is now between 70% and 80%. The number of long-term survivors, off- threatment for at least 5 years, is rising rapidly and is becoming a new population, which needs a special care. It is becoming increasingly important to know...
journal_title：Minerva pediatrica
pub_type： 杂志文章,评审
doi：
更新日期：2005-12-01 00:00:00
abstract：:Non-alcoholic fatty liver disease (NAFLD) encompasses a range of liver histology severity and outcomes in the absence of chronic alcohol use. The mildest form is simple steatosis in which triglycerides accumulate within hepatocytes. A more advanced form of NAFLD, non-alcoholic steatohepatitis (NASH), includes inflamma...
journal_title：Minerva pediatrica
pub_type： 杂志文章,评审
doi：
更新日期：2010-12-01 00:00:00
abstract：:The Authors describe a case report of a girl of 7 years affected by visceral leishmaniasis (VL) complicated by herpes zoster (Hz). Hz infection is unusual in paediatric age, but it may complicate immunodeficiency states. VL causes, as well known, T cell immunity depression: Hz infection could be facilitated by this si...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
abstract：OBJECTIVES:During a survey regarding infant health in 7 regions, diffusion and length of time of breast-feeding nowadays in Italy were studied. MATERIALS AND METHODS:By OMS Epi methodology, 210 children sampled from each area of study and specialized health workers carried out the interviews at home using a specific q...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：1995-11-01 00:00:00
abstract：AIM:The aim of this study was to evaluate the influence of colostomy type on morbidity during the treatment of anorectal malformations. METHODS:Sixty-eight infants (male: female ratio 1.3:1) with anorectal malformations that required colostomy were treated in our clinics during the period 1991-2001. Of these patients,...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2004-08-01 00:00:00
abstract：:The Femoral hypoplasia - unusual facies syndrome (FHUF) or Femoral - facial syndrome (FFS) was at first described in 1975. Up to now about 60 cases have been reported. According to our knowledge only 4 cases have had congenital central nervous system's malformations, furthermore the main stages of psychomotor developm...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2011-08-01 00:00:00
abstract：AIM:The neurofibromatosis type 1 (NF1) is an autosomal dominant neurocutaneous disease. In 40-70% of cases are described signal hyperintensity on MRI, called unidentified bright objects (UBO). Their correlation with clinical disorders is still debated. The present study investigated the correlation between the UBOs and...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2013-08-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to asses the validity of the TCB nomogram for the European population for predicting significant hyperbilirubinemia in healthy term and late-preterm newborns. METHODS:This observational study was conducted from February 2009 to December 2009 in the well-baby nurseries of Gemelli hos...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2010-06-01 00:00:00
abstract：:This work aims at describing a particular case of Budd-Chiari syndrome in a ten-year-old girl. In our patient, the subjective and objective features of this disease, which is already rare during childhood, are associated with a well-assessed polyposis in the blind intestine (intestinum caecum). In our opinion, a possi...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：1995-06-01 00:00:00
abstract：:Infants born prematurely before 37 weeks of gestational age (GA) have particular anatomical, immunological and metabolic characteristics that predispose them, even in the absence of diseases at birth, to severe morbidity. Respiratory syncytial virus (RSV) is the leading cause of hospitalization for lower respiratory t...
journal_title：Minerva pediatrica
pub_type： 杂志文章,评审
doi：10.23736/S0026-4946.18.05300-8
更新日期：2018-12-01 00:00:00
abstract：:One of the principal duties of a staff nurse working in a NICU is the assistance of the ventilated infants. The management of the endotracheal tube is a key moment in the neonatal care and it is fundamental to prevent the ventilator induced lung injury and the change in the perfusion (especially in the brain) that may...
journal_title：Minerva pediatrica
pub_type： 杂志文章,评审
doi：
更新日期：2010-06-01 00:00:00
abstract：BACKGROUND:There has been a paucity of data about the therapeutic efficacy of bronchoalveolar lavage (BAL) for pediatric refractory Mycoplasma pneumonia pneumonia (RMPP) complicated with atelectasis. This study aims to evaluate the clinical effectiveness and safety of BAL in pediatric RMPP inpatients complicated with a...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：10.23736/S0026-4946.20.05538-3
更新日期：2020-04-02 00:00:00
abstract：:The dominant cause of mortality, morbidity and hospitalization worldwide is cardiac complications, and are the major public health problem in adult populations. The worldwide research is being focused on the idea that cardiovascular disease is an early life pathological state. Early unfavorable exposures, acting in di...
journal_title：Minerva pediatrica
pub_type： 杂志文章,评审
doi：10.23736/S0026-4946.16.04713-7
更新日期：2017-06-01 00:00:00
abstract：:Cystic fibrosis (CF) is a genetic disease associated with recurrent lung infections, that represent a major cause of mortality and morbidity. Cystic fibrosis requires frequent antibiotic treatments, sometimes by mouth or via aerosol but often via the intravenous route. Totally implanted venous access devices (ports) a...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2009-10-01 00:00:00
abstract：BACKGROUND:The aim of this study is to investigate the changes of developmental and behavioral profile in a domestic adoptees sample. METHODS:Thirty-six domestic adoptive families were recruited, resulting in a sample of 39 children. Families were sent a general questionnaire for collecting data related to the childre...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2020-10-01 00:00:00
abstract：:The diagnosis and treatment of anorexia nervosa (AN) in children and adolescents has some commonality but also differs from that of this condition in adults. A new understanding of AN is emerging: research data from the fields of epidemiology, genetics, and brain biology, suggest that there may be an underlying brain ...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2013-02-01 00:00:00
abstract：:Noonan syndrome was first described over 20 years ago by Noonan and Ehmke. They defined a specific group of nine patients with valvular pulmonary stenosis who, in addition, had short stature, mild mental retardation, hypertelorism and unusual facies. The incidence of Noonan syndrome has been estimated to be between 1 ...
journal_title：Minerva pediatrica
pub_type： 杂志文章,评审
doi：
更新日期：1993-09-01 00:00:00
