Anorexia nervosa in children and adolescents: diagnosis, treatment and the role of the pediatrician.

Abstract:

:The diagnosis and treatment of anorexia nervosa (AN) in children and adolescents has some commonality but also differs from that of this condition in adults. A new understanding of AN is emerging: research data from the fields of epidemiology, genetics, and brain biology, suggest that there may be an underlying brain diathesis predisposing towards AN. It is now proposed that that what starts as a harmless diet, once it turns into a more prolonged food restriction may trigger an eating disorder in a genetically neurobiologically predisposed population. The condition may be then perpetuated by the biochemical changes induced by weight loss, ketosis, and the impact of the ensuing malnutrition on the brain (starvation illness). This change of paradigm from a psychological understanding to a neurobiological conceptualization calls for an early intervention to assure nutritional rehabilitation as soon as an eating disorder is suspected in children, without needing to wait for all the classical features of the diagnosis as seen in adults. This new model is agnostic about the origins of the disease and questions the classic assumption of "an underlying family pathology". It gives strong support to treatments such as Family Based Treatment, also referred to as the "Maudsley method". Essentially this consists of empowering parents to monitor and supervise the nutritional rehabilitation of their children. Hence pediatricians no longer need to be bystanders when treating these children and adolescents. They now have a clearly defined role: early diagnosticians, clinical monitors (of potential medical complications), nutrition advisors, and as members of a multidisciplinary team, patient and family advocates and educators.

journal_name

Minerva Pediatr

journal_title

Minerva pediatrica

authors

Silber TJ

subject

Has Abstract

pub_date

2013-02-01 00:00:00

pages

1-17

issue

1

eissn

0026-4946

issn

1827-1715

pii

R15133880

journal_volume

65

pub_type

杂志文章
  • [Treatment of bronchial asthma in chidren].

    abstract::Asthma is a condition characterised by airways inflammation and bronchial hyperresponsiveness to specific and aspecific spasmogens associated with reversible airways obstruction. The bronchomotor tone is the result of an interaction between neurotransmitter release and local mediators. The efferent neurohumoral pathwa...

    journal_title:Minerva pediatrica

    pub_type: 杂志文章,评审

    doi:

    authors: Rossi F,Gallelli L,Marrocco G,Capristo C,Miraglia Del Giudice M,Maisto A,Brunese FP,D'Agostino B,Capristo AF

    更新日期:2000-11-01 00:00:00

  • [Tuberculoma complicating tuberculous meningitis: description of one paediatric case].

    abstract::Intracranial tuberculoma is a possible complication of meningeal, miliary or pulmonary tuberculosis. In developing countries it represents 30% of space-occupying intracranial lesions, in industrialised countries only 0.1-0.2%. One recently recognised phenomenon is the development ex novo or the enlargement of the tube...

    journal_title:Minerva pediatrica

    pub_type: 杂志文章

    doi:

    authors: Ruggeri C,Valenzise M,Alosi MM,Scibilia G,Wasniewska M

    更新日期:2005-10-01 00:00:00

  • [Neuropsychological development in children with focal brain injury].

    abstract::The study of children with focal brain injury has important implications from a clinical and theoretical perspective. Clinical data on children with congenital or early acquired lesions indicates that the cognitive sequelae are different from those resulting from similar damage sustained in adulthood. These difference...

    journal_title:Minerva pediatrica

    pub_type: 杂志文章,评审

    doi:

    authors: Masi G,Marcheschi M,Brovedani P,Pfanner P

    更新日期:1993-06-01 00:00:00

  • The concept of post-traumatic mood disorder and its implications for adolescent suicidal behavior.

    abstract::Post-traumatic stress disorder (PTSD) is a common psychiatric disorder which is frequently comorbid with major depressive disorder (MDD). It has been suggested that some or all individuals diagnosed with comorbid PTSD and MDD have a separate psychobiological condition that can be termed ''post-traumatic mood disorder'...

    journal_title:Minerva pediatrica

    pub_type: 杂志文章,评审

    doi:

    authors: Sher L

    更新日期:2008-12-01 00:00:00

  • [Determination of the cut-off for marker TPA in healthy children].

    abstract::In the present study the authors investigated the normal range of the marker TPA in the sera of 100 children (apparently healthy) aged from 0 to 6 years. Well-defined criteria as guide-lines to the interpretation of laboratory results are a very urgent necessity for the expanding utilization of clinical laboratory dat...

    journal_title:Minerva pediatrica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Magrì G,Giargia L

    更新日期:1994-11-01 00:00:00

  • Sixteen years of experience with persistent chylothorax in children.

    abstract:BACKGROUND:Persistent chylothorax in children is rare. Conservative management represents the gold standard but, in case of failure (persistent effusion or relapse), surgery must be considered. This paper aimed at presenting our series of patients who underwent surgical treatment of persistent idiopathic chylothorax an...

    journal_title:Minerva pediatrica

    pub_type: 杂志文章

    doi:10.23736/S0026-4946.16.04324-3

    authors: Pini Prato A,Bava GL,Dalmonte P,Vercellino N,Michelazzi A,Pio L,Avanzini S,Mattioli G

    更新日期:2017-12-01 00:00:00

  • Transanal irrigation and intestinal transit time in children with myelomeningocele.

    abstract:AIM:Myelomeningocele (MMC), among others functions, affects colorectal motility and bowel emptying, and often leads to constipation, faecal incontinence, or a combination of both. We investigated the benefits of transanal irrigation (TI) in children with MMC through the radiological study of intestinal transit time. M...

    journal_title:Minerva pediatrica

    pub_type: 杂志文章

    doi:

    authors: Marte A,Borrelli M

    更新日期:2013-06-01 00:00:00

  • Timely diagnosis of comorbid pervasive developmental disorder and bipolar disorder.

    abstract::Little is known about the overlapping symptoms and comorbidity of pediatric bipolar disorder (BD) and pervasive developmental disorders (PDD) in youth. The aim of this study was to clearly differentiate the symptoms, understand the prevalence and patterns of comorbid presentations, as well as to provide a summary of e...

    journal_title:Minerva pediatrica

    pub_type: 杂志文章

    doi:

    authors: McDonnell MA,Hamrin V,Moffett J,Durso S

    更新日期:2008-02-01 00:00:00

  • The online sexual offender: what we know to date.

    abstract:INTRODUCTION:Online grooming is an active communicative entrapment network involving a wide range of techniques. The interactions that groomers have with minors online are complex. The purpose of the present literature review is to contribute to the existing knowledge base regarding online sex offender typologies, pred...

    journal_title:Minerva pediatrica

    pub_type: 杂志文章

    doi:10.23736/S0026-4946.20.05621-2

    authors: Del Castillo G,Gandolfi CE,Mosillo M,Forni G,Pietronigro A,Tiwana N,Pellai A

    更新日期:2020-05-15 00:00:00

  • Qualitative and quantitative revaluation of specific learning disabilities: a multicentric study.

    abstract:BACKGROUND:Specific learning disabilities are disorders that affect the instrumental skills of academic learning, leaving intact the general intellectual functioning. It is possible to distinguish: dyslexia, dysorthography, dysgraphia, and dyscalculia. The diagnosis is made according to DSMV. The aim of this study is t...

    journal_title:Minerva pediatrica

    pub_type: 杂志文章

    doi:10.23736/S0026-4946.18.05036-3

    authors: Operto FF,Mazza R,Buttiglione M,Craig F,Frolli A,Pisano S,Margari L,Coppola G

    更新日期:2018-04-12 00:00:00

  • Effects of antiepileptic therapy on bone mineral status evaluated by phalangeal quantitative ultrasound in pediatric patients with epilepsy and motor impairment.

    abstract:BACKGROUND:In epileptic patients with motor disability, it's difficult to disentangle the effects of antiepileptic drugs (AEDs) on bone health from those provoked by impaired mobility. The aim of this study was to evaluate the effects of AEDs on bone mineral status by phalangeal quantitative ultrasound (QUS), a no-radi...

    journal_title:Minerva pediatrica

    pub_type: 杂志文章

    doi:10.23736/S0026-4946.18.05235-0

    authors: Terrone G,Gragnaniello V,Esposito A,Del Puente A,Del Giudice E

    更新日期:2019-05-23 00:00:00

  • [Organisational aspects of a donated breast milk bank: experience of the Treviso hospital].

    abstract:AIM:This study analyses the organisational aspects and the volume of milk managed by the donated breast milk bank (banca del latte umano donato, BLUD) in Treviso. METHODS:The data gathered refer to the years 2003, 2004 and 2005. In particular the hygiene methodology is described in order to obtain a high-quality produ...

    journal_title:Minerva pediatrica

    pub_type: 杂志文章

    doi:

    authors: Paccagnella A,Michieletto S,Pitassi I,Baruffi C,Pizzolato D,Marcon ML,Saia OS,Toscani P,Moretti G,Foscolo G

    更新日期:2007-08-01 00:00:00

  • [Height percentiles of children at 6 to 11 years of age in the area of Lazio].

    abstract:BACKGROUND:In this paper we present growth height standards obtained by an auxological study on a primary school population of central Italy (Lazio), in the 1991-1992 and 1992-1993 school-years. METHODS:4,175 children were included in the study: 2,024 females and 2,151 males, aged from 6 to 11 years. The sampling rate...

    journal_title:Minerva pediatrica

    pub_type: 杂志文章

    doi:

    authors: Schwarzenberg TL,Loreti P,Sgricia S,Acconcia P,Tiberi R,Buffone MR,Coltellacci M

    更新日期:1997-04-01 00:00:00

  • A tertiary care center's experience with febrile seizures: evaluation of 632 cases.

    abstract:BACKGROUND:The aim of this paper was to evaluate demographic and prognostic features of febrile seizures (FSs) in a tertiary center in Turkey. METHODS:A retrospective study of 632 children with FS was conducted from January 1995 to January 2002 in the pediatric neurology and general pediatrics departments of Istanbul ...

    journal_title:Minerva pediatrica

    pub_type: 杂志文章

    doi:10.23736/S0026-4946.16.04081-0

    authors: Elshana H,Özmen M,Uzunhan TA,Uzunhan O,Ünüvar E,Kiliç A,Tatli B,Aydinli N,Çalişkan M

    更新日期:2017-06-01 00:00:00

  • [Congenital abnormalities of the temporal bone. Clinical picture and therapeutic indications].

    abstract::The embryology of the ear and the different congenital anomalies depending on the arrest in development at a particular embryologic date are reviewed. The historical and the actual attitude towards surgical correction is discussed. The classification system, the evaluation and patients selection, the timing of auricul...

    journal_title:Minerva pediatrica

    pub_type: 杂志文章,评审

    doi:

    authors: Salvinelli F,Trivelli M,Greco F

    更新日期:2000-12-01 00:00:00

  • Ventilator associated pneumonia due to carbapenem resistant microorganisms in children.

    abstract:BACKGROUND:Infections due to carbapenem resistant pathogens have become a major health threat especially for hospitalized patients. Acinetobacter baumanii (AB) and Pseudomonas aeruginosa (PA) are important pathogens causing ventilator-associated pneumonia (VAP) with a trend of high resistance to carbapenems. The aim of...

    journal_title:Minerva pediatrica

    pub_type: 杂志文章

    doi:10.23736/S0026-4946.17.04284-0

    authors: Kara SS,Polat M,Tapisiz A,Kalkan G,Simsek H,Tezer H

    更新日期:2019-08-01 00:00:00

  • [Treatment of childhood obesity].

    abstract::This article provides current guidelines on the treatment and prevention of childhood obesity. Since factors involved in obesity change with age, the therapeutic approach in pre-school children will be different from pupils and adolescents. The treatment will also be modulated on the basis of weight excess, weight gai...

    journal_title:Minerva pediatrica

    pub_type: 指南,杂志文章,实务指引

    doi:

    authors: Trifirò G,Salvatoni A,Tanas R,Brambilla P,Maffeis C,Gruppo di Studio sull'Obesità della SIEDP.

    更新日期:2003-10-01 00:00:00

  • RSV prophylaxis in premature infants.

    abstract::Infants born prematurely before 37 weeks of gestational age (GA) have particular anatomical, immunological and metabolic characteristics that predispose them, even in the absence of diseases at birth, to severe morbidity. Respiratory syncytial virus (RSV) is the leading cause of hospitalization for lower respiratory t...

    journal_title:Minerva pediatrica

    pub_type: 杂志文章,评审

    doi:10.23736/S0026-4946.18.05300-8

    authors: Del Vecchio A,Franco C,Del Vecchio K,Umbaldo A,Capasso L,Raimondi F

    更新日期:2018-12-01 00:00:00

  • Bone cell biology and pediatric renal osteodystrophy.

    abstract::Patients with chronic kidney disease (CKD) show a broad spectrum of clinical symptoms intimately related to the disturbed mineral and bone metabolism and summarized as CKD-mineral-bone disorder (CKD-MBD). Whereas in adults an impaired bone metabolism translates mainly into an increased risk of fractures, in pediatric ...

    journal_title:Minerva pediatrica

    pub_type: 杂志文章,评审

    doi:

    authors: Haffner D,Fischer DC

    更新日期:2010-06-01 00:00:00

  • [Intracranial tumors in the 1st year of life].

    abstract::The introduction of the new diagnostic tools for neuroimaging has resulted in the early recognition of congenital brain tumors. In the present report we describe 39 children, in whom the diagnosis of an intracranial tumor has been obtained during the first 12 months of life. These patients represent 14.4% of a pediatr...

    journal_title:Minerva pediatrica

    pub_type: 杂志文章

    doi:

    authors: Caldarelli M,Ceddia A,Di Rocco C,Iannelli A,Velardi F

    更新日期:1990-11-01 00:00:00

  • [Psychopathological risk in children with early onset of partial epilepsy].

    abstract::In this study we compare the peculiarities of psychopathological risk in children with partial epilepsy versus children with chronic illness. Sixteen children affected by epilepsy with partial seizures, symptomatic or cryptogenetic (group A), are compared with 16 children affected by diabetes mellitus type 1 (group B)...

    journal_title:Minerva pediatrica

    pub_type: 杂志文章

    doi:

    authors: Bargagna S,Guerrini R,Millepiedi S

    更新日期:1995-05-01 00:00:00

  • Treatment of hepatitis B and C in children.

    abstract::Chronic viral hepatitis B and C infections are highly prevalent and create a substantial burden to healthcare systems globally. These two chronic infections are the cause of significant global morbidity and mortality with approximately 1 million annual deaths attributable to them and their sequelae. Children are vulne...

    journal_title:Minerva pediatrica

    pub_type: 杂志文章,评审

    doi:

    authors: El-Shabrawi M,Hassanin F

    更新日期:2014-10-01 00:00:00

  • Pharmacological strategies in the idiopatic pulmonary fibrosis of children.

    abstract::Idiopathic pulmonary fibrosis is characterized by radiographically evident interstitial infiltrates and progressive dyspnea with rapid decline of overall lung functions. The clinical course of this disease is highly variable; however, its prognosis remains poor without adequate and prompt therapeutical support. Due to...

    journal_title:Minerva pediatrica

    pub_type: 杂志文章,评审

    doi:

    authors: Rigante D,Stabile A

    更新日期:2004-04-01 00:00:00

  • Recognition and initial management of cardiac emergencies in children.

    abstract::One may have only minutes to change the trajectory of a child who is deteriorating from either congenital or acquired cardiac disease. However, these children may present with rather cryptic patterns of symptoms (e.g. failure to thrive, lethargy, colic, neonatal shock, respiratory distress, wheezing and syncope with e...

    journal_title:Minerva pediatrica

    pub_type: 杂志文章,评审

    doi:

    authors: Hunt EA,Brunetti M,Nelson KL,Shilkofski NA,Peddy SB

    更新日期:2009-04-01 00:00:00

  • [Measuring the mineral content of the distal radius in the age of growth].

    abstract::A study was carried out to characterize in the growing skeleton the absorptiometric measurement of the ultradistal radial epiphysis where the trabecular bone is higher than at proximal scanning planes. The study showed that a radius scan, 1 to 1.4 cm proximal to the ulnar tip, and consequently 4 to 6 mm proximal to th...

    journal_title:Minerva pediatrica

    pub_type: 杂志文章

    doi:

    authors: Pasolini D,Weber G,Rubinacci A,Rinaldi GP,Chiumello G

    更新日期:1991-07-01 00:00:00

  • Identification of obesity in children and teenagers.

    abstract:BACKGROUND:Obesity is a condition that increases the risk of developing several health problems, resulting in high health care costs worldwide. Therefore, it is important to investigate several avenues for the control of this condition. This study aimed to identify a dermatoglyphical condition that distinguishes obesit...

    journal_title:Minerva pediatrica

    pub_type: 杂志文章

    doi:10.23736/S0026-4946.20.05731-X

    authors: Alberti A,Ruiz Reyes MA,De Jesus JA,Rossoni C,Grigollo L,Da Silva BB,Fin G,Baretta E,Comim CM,Nodari RJ Jr

    更新日期:2021-01-13 00:00:00

  • [Antiendomysium antibodies and antigliadin antibodies in diagnosis and follow-up of celiac disease].

    abstract::Anti-endomysium antibodies (AEA) and Antigliadin antibodies (AGA) have been compared in a group of coeliac patients (17 with untreated coeliac disease, 56 after gluten free diet and 14 after gluten challenge), in 69 patients with various intestinal pathological conditions, and in 40 healthy children, in order to appre...

    journal_title:Minerva pediatrica

    pub_type: 杂志文章

    doi:

    authors: Cataldo F,Trippiedi MA,Marino V,Maltese I,Traverso G,Paternostro D,Albeggiani A

    更新日期:1993-01-01 00:00:00

  • Diagnostic workup of urinary tract infections within the first 24 months of life, in the era of prenatal diagnosis. The contribution of different imaging techniques to clinical management.

    abstract:AIM:The aim of this study was to evaluate the role of different techniques in the diagnostic workup of children with negative prenatal ultrasonogram, referred for urinary tract infection (UTI) within the first 24 months. METHODS:One-hundred and forty-seven patients, 71 males/76 females were studied. All patients were ...

    journal_title:Minerva pediatrica

    pub_type: 杂志文章

    doi:

    authors: Calisti A,Perrotta ML,Oriolo L,Ingianna D,Sciortino R

    更新日期:2005-10-01 00:00:00

  • Nasal microbiome in chronic rhinosinusitis.

    abstract:INTRODUCTION:Chronic rhinosinusitis (CRS) is defined as an inflammatory disorder of the paranasal sinuses and of the nasal mucosa that lasts 12 weeks or longer. In CRS microbes contribute to the disease pathogenesis. Clinical microbiology is focused on finding single pathogens that causes the disease and the main goal ...

    journal_title:Minerva pediatrica

    pub_type: 杂志文章

    doi:10.23736/S0026-4946.20.05850-8

    authors: Miraglia Del Giudice M,Parisi GF,Indolfi C,Manti S,Leonardi S,Decimo F,Ciprandi G

    更新日期:2020-07-29 00:00:00

  • Specific learning disorders and anxiety: a matter of school experience?

    abstract:BACKGROUND:Specific learning disorders (SLDs) are a group of neuropsychological disorders which reduce a child's ability to read and/or write and/or use numbers. Internalizing disorders, and in particular anxiety, has been reported as a relatively common comorbidity in children with reading difficulties. We conducted t...

    journal_title:Minerva pediatrica

    pub_type: 杂志文章

    doi:

    authors: Chiappedi M,Baschenis IM

    更新日期:2016-02-01 00:00:00