Abstract：
:Idiopathic pulmonary fibrosis is characterized by radiographically evident interstitial infiltrates and progressive dyspnea with rapid decline of overall lung functions. The clinical course of this disease is highly variable; however, its prognosis remains poor without adequate and prompt therapeutical support. Due to the fact that barely a quarter of patients responds to steroids alone, cytostatics are often prescribed simultaneously with low dose corticosteroids in the pediatric age too. Cytokine or anti-cytokine therapy and the role of new antifibrotic drugs are still at the experimental stage of definition and will be discussed in the following review.
journal_name
Minerva Pediatrjournal_title
Minerva pediatricaauthors
Rigante D,Stabile Akeywords:
subject
Has Abstractpub_date
2004-04-01 00:00:00pages
161-5issue
2eissn
0026-4946issn
1827-1715journal_volume
56pub_type
杂志文章,评审abstract：AIM:Macrophage activation syndrome (MAS) is a rare complication of childhood with rheumatic disease. This syndrome has been reported as a complication of many rheumatic diseases, most commonly in systemic onset of juvenile idiopathic arthritis (SoJIA). The aim of this study was evaluation the rate, symptoms and outcome...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2011-12-01 00:00:00
abstract：:QT prolongation is rarely seen after acute stress reactions such as burn injury and severe head trauma. Although pathophysiologic mechanism is not entirely clear, acute stress is thought to contribute to the inhomogeneity of ventricular repolarization and it is hypothesized that QTc dispersion increases with severity ...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2006-12-01 00:00:00
abstract：:Acute disseminated staphylococcal disease (ADSD) constitutes a potentially fatal and alarmingly increasing disorder. We describe an unusual case of a two-and-a-half-year-old female with community-acquired methicillin-resistant Staphylococcus aureus induced septic shock complicated by osteomyelitis and deep vein thromb...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2013-04-01 00:00:00
abstract：:Insulin-dependent diabetes mellitus is associated to important micro and macro vascular complications. A good metabolic control can reduce the risk of complications. Aim of the study was to evaluate the metabolic control in adolescent diabetic patients using an educational system with graphic visualisation of capillar...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：1996-06-01 00:00:00
abstract：:The study of children with focal brain injury has important implications from a clinical and theoretical perspective. Clinical data on children with congenital or early acquired lesions indicates that the cognitive sequelae are different from those resulting from similar damage sustained in adulthood. These difference...
journal_title：Minerva pediatrica
pub_type： 杂志文章,评审
doi：
更新日期：1993-06-01 00:00:00
abstract：:The association of congenital anal stenosis, or other anal and rectal malformation, sacral defect and a presacral mass is known as the Currarino syndrome described for the first time in 1981. Currarino et al. proposed that abnormal endoectodermal adhesions and notochordal defects in early fetal life may result in a fi...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2005-06-01 00:00:00
abstract：AIM:Myelomeningocele (MMC), among others functions, affects colorectal motility and bowel emptying, and often leads to constipation, faecal incontinence, or a combination of both. We investigated the benefits of transanal irrigation (TI) in children with MMC through the radiological study of intestinal transit time. M...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2013-06-01 00:00:00
abstract：:Severe atopic dermatitis causes major impairment in the life of both children and their parents. Generally, symptoms can be controlled with emollients, topical steroids, antibiotics, antihistaminic but some patients remain intensely ill and may require treatment with systemic steroids and so on. Cyclosporin has been f...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2004-04-01 00:00:00
abstract：:The authors report the case of a 13-year-old girl affected with urethritis, conjunctivitis, and oligoarticular arthritis. These symptoms represent the classical triad of Fiessinger-Leroy-Reiter's syndrome. The research for HIV was negative and the antigen HLA B27 was absent. The young patients has been treated by FANS...
journal_title：Minerva pediatrica
pub_type： 杂志文章,评审
doi：
更新日期：1993-07-01 00:00:00
abstract：:This is the first scientific study on Mary Sandrucci, who has been director of the Pediatric Clinic of the University of Turin from 1965-1966 up to 31 December 1989. Prof. Sandrucci led major studies on congenital heart disease, was the first Italian and among the first in Europe to describe phocomelia cases, to repor...
journal_title：Minerva pediatrica
pub_type： 传,历史文章,杂志文章
doi：
更新日期：2011-04-01 00:00:00
abstract：:Contiguous gene deletion syndromes: the importance of an accurate genetic definition for a careful clinical monitoring. Contiguous gene deletion syndromes are so named because the deletion manifests as a distinctive cluster of otherwise unrelated single-gene disorders in the same subject. An accurate genetic definitio...
journal_title：Minerva pediatrica
pub_type： 杂志文章,评审
doi：
更新日期：2010-06-01 00:00:00
abstract：:Celiac disease (CD) is one of the most common immune-mediated diseases with a worldwide prevalence of around 1%, although a couple of decades ago the disease was thought to be very rare. CD is characterized by an inadequate inflammatory response to gluten in genetically susceptible individuals. In this inflammatory re...
journal_title：Minerva pediatrica
pub_type： 杂志文章,评审
doi：
更新日期：2012-06-01 00:00:00
abstract：AIM:Childhood leukaemia treatment contains multiple chemotherapeutic agents in high doses that can cause severe toxic effects on heart and other vital organs. In this respect patients taking cancer chemotherapy are followed for these adverse effects. Echocardiographic myocardial performance index (MPI) was reported as ...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2007-04-01 00:00:00
abstract：BACKGROUND:The aim of this study was to investigate the potential of dexfenfluramine (dF) for reducing cardiovascular risk factors and improving compliance towards diet in a group of young patients hospitalized for essential obesity of high degree (BMI > or = 35). METHODS:103 adolescents (mean age 15.4 +/- 0.2) partic...
journal_title：Minerva pediatrica
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1997-03-01 00:00:00
abstract：:Non-alcoholic fatty liver disease (NAFLD) encompasses a range of liver histology severity and outcomes in the absence of chronic alcohol use. The mildest form is simple steatosis in which triglycerides accumulate within hepatocytes. A more advanced form of NAFLD, non-alcoholic steatohepatitis (NASH), includes inflamma...
journal_title：Minerva pediatrica
pub_type： 杂志文章,评审
doi：
更新日期：2010-12-01 00:00:00
abstract：:Joint hypermobility refers to the ability that a joint has to move beyond its normal range of motion. It is common in the general population, particularly in children. While many individuals manifesting joint hypermobility are healthy, this feature can accompany a wide range of symptoms and systemic disorders, whose m...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：10.23736/S0026-4946.20.05766-7
更新日期：2020-04-01 00:00:00
abstract：BACKGROUND:COVID-19 has quickly become a worldwide threat to health, travel, and commerce. Studies adressing the clinical-functional presentation of viral infection and physiotherapy management in children are scarce. The purpose statement was to provide current perspectives on the physiotherapy interventions for manag...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：10.23736/S0026-4946.20.06100-9
更新日期：2020-10-27 00:00:00
abstract：:Congenital diaphragmatic hernia (CDH) remains one of the major challenges in neonatal surgery. Survival rate has increased in the last decades mainly due to perinatal care and surgical technique improvements. Classically, a laparotomy has been performed after cardiovascular and respiratory stabilization. Introduction ...
journal_title：Minerva pediatrica
pub_type： 杂志文章,评审
doi：10.23736/S0026-4946.17.05110-6
更新日期：2018-06-01 00:00:00
abstract：:In this study the authors evaluated the correlation between plasma somatomedin C (SmC) levels and auxological features in 129 short children, who have been subdivided into four groups: classical growth hormone (GH) deficiency (14 prepubertal subjects), normal responses to provocative stimuli tests, but diminished spon...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：1991-09-01 00:00:00
abstract：BACKGROUND:The aim of our study was multifaceted neurodevelopmental examination of children born prematurely with very low birth weight (VLBW) in order to evaluate the usefulness of popularly used tests. The second aim of the study was exploration of risk and protective factors of neurodevelopmental impairment. METHOD...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：10.23736/S0026-4946.16.04513-8
更新日期：2019-08-01 00:00:00
abstract：:This article provides current guidelines on the treatment and prevention of childhood obesity. Since factors involved in obesity change with age, the therapeutic approach in pre-school children will be different from pupils and adolescents. The treatment will also be modulated on the basis of weight excess, weight gai...
journal_title：Minerva pediatrica
pub_type： 指南,杂志文章,实务指引
doi：
更新日期：2003-10-01 00:00:00
abstract：:To establish the effectiveness of flunisolide + salbutamol vs salbutamol alone administered by metered aerosol in the phlogistic obstructive diseases, 18 children were evaluated. The treatments were evaluated on the basis of ventilatory function parameters and of tolerance. The results proved positive for all drugs, t...
journal_title：Minerva pediatrica
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1990-06-01 00:00:00
abstract：:Early recognition of shock is the key to successful resuscitation in critically ill children. Often, shock results in or co-exists with myo-cardial dysfunction or acute lung injury. Recognition and appropriate management of these insults is crucial for successful outcomes. Resuscitation should be directed to restorati...
journal_title：Minerva pediatrica
pub_type： 杂志文章,评审
doi：
更新日期：2009-02-01 00:00:00
abstract：:The remarkable effectiveness of surfactant in neonatology suggested its use also in adults as well as in children on the basis of the pulmonary pathophysiology. We describe a case of an 18 month-old child affected by acute respiratory distress syndrome (ARDS) due to asphyxy by gastric juice inhalation, successfully tr...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2007-12-01 00:00:00
abstract：:More than one million neonatal deaths every year in the world are attributable to infection. In nurseries, infections occur with a reported incidence of 0.3-3%; in Neonatal Intensive Care Units (NICUs) the reported incidence is 7-24.5%, and up to 40% in newborns with birth weight less than 1000 g or gestational age at...
journal_title：Minerva pediatrica
pub_type： 杂志文章,评审
doi：
更新日期：2013-02-01 00:00:00
abstract：BACKGROUND:The aim of this paper was to examine the present situation of adolescents admission for respiratory emergency, management of these patients, identify strategies for the best therapeutic options and better collaboration. METHODS:We have gathered data of adolescent patients who were referred to the Emergency ...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2002-12-01 00:00:00
abstract：:This study describes the blood pressure (BP), heart rate and weight distribution of 1214 school-age children (6-11 years old) in Messina. The systolic BP is significantly correlated with weight in every age and in both sexes. The incidence of BP values equal or above the 95 degrees percentile are significantly higher ...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：1990-04-01 00:00:00
abstract：:Follow-up studies of low-birth-weight (LBW) neonates have shown a high incidence of growth failure in the first years of life. We evaluated the growth attainment (weight, length and head circumference) in 182 LBW neonates discharged from our Intensive Care Unit between 1982-84 and included in a 3 years follow-up progr...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：1993-03-01 00:00:00
abstract：BACKGROUND:In epileptic patients with motor disability, it's difficult to disentangle the effects of antiepileptic drugs (AEDs) on bone health from those provoked by impaired mobility. The aim of this study was to evaluate the effects of AEDs on bone mineral status by phalangeal quantitative ultrasound (QUS), a no-radi...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：10.23736/S0026-4946.18.05235-0
更新日期：2019-05-23 00:00:00
abstract：:One may have only minutes to change the trajectory of a child who is deteriorating from either congenital or acquired cardiac disease. However, these children may present with rather cryptic patterns of symptoms (e.g. failure to thrive, lethargy, colic, neonatal shock, respiratory distress, wheezing and syncope with e...
journal_title：Minerva pediatrica
pub_type： 杂志文章,评审
doi：
更新日期：2009-04-01 00:00:00
