[The Currarino syndrome: two case reports].

Abstract:

:The association of congenital anal stenosis, or other anal and rectal malformation, sacral defect and a presacral mass is known as the Currarino syndrome described for the first time in 1981. Currarino et al. proposed that abnormal endoectodermal adhesions and notochordal defects in early fetal life may result in a fistula between the gut and the spinal canal with enteric elements ventrally and neural elements dorsally. This abnormality appears to be a variant of the split notochord syndrome. The occurrence of Currarino's triad of anomalies is familial in more than 50% of cases. The most important suggested hypothesis of transmission is an X-linked dominant pattern, but most of the other reports are consistent with an autosomal dominant mode of inheritance. The medical therapy is poorly successful and, therefore, the surgical treatment is recommended for Currarino's syndrome.

journal_name

Minerva Pediatr

journal_title

Minerva pediatrica

authors

Di Meglio D,Capobianco A,Tramontano A,Gaglione G,Saggiomo G

keywords:

subject

Has Abstract

pub_date

2005-06-01 00:00:00

pages

147-52

issue

3

eissn

0026-4946

issn

1827-1715

journal_volume

57

pub_type

杂志文章
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    authors: Saggese G,Baroncelli GI,Bertelloni S

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    authors: Di Rocco C,Iannelli A,Tamburrini G

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    authors: Santhanam I,Ranjit S,Kissoon N

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  • [Antiendomysium antibodies and antigliadin antibodies in diagnosis and follow-up of celiac disease].

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    doi:

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  • [RAST positivity for food in atopic dermatitis].

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    doi:

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  • [Indications for the use of external fixator in orthopedics and traumatology during the developmental age].

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    doi:

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