[Pharmacokinetics of broxaterol in asthmatic children].

Abstract:

:Pharmacological profile of broxaterol, a new beta adrenergic compound, was investigated in 12 asthmatic children (6 male and 6 female with age 8-13 years). This study was performed from November to May, and venous blood was collected after 30, 45, 120, 180, 240 minutes from administration of 0.5 mg broxaterol; the urine was collected every 4 hours drug intake (0-4, 4-8, 8-12 hours). Drug absorption proved very fast: T max was 0.9 hours and Cmax was 2.05 micrograms/ml. T 1/2 was 2.3 hours. The urine concentration of broxaterol in the urine 0-4 and 4-8 hours after administration, was 6.11 and 2.3% (as drug percentage), after 8 hours no broxaterol was evaluated in the urine. Pharmacological profile of broxaterol in asthmatic children and adults is comparable.

journal_name

Minerva Pediatr

journal_title

Minerva pediatrica

authors

Flores D'Arcais A,Crippa L,De Biase D,Romagnoni G

keywords:

subject

Has Abstract

pub_date

1992-09-01 00:00:00

pages

421-5

issue

9

eissn

0026-4946

issn

1827-1715

journal_volume

44

pub_type

杂志文章
  • [Achalasic megaesophagus with onset in the 1st year of life. A case report].

    abstract::We report a case of esophageal achalasia in a nine months old baby. Recurrent cough and cyanosis were the most important clinical findings. Esophagomyotomy remarkably improved the clinical symptoms. Disorders of esophageal motility may be an important cause of respiratory emergencies in the first year of life. ...

    journal_title:Minerva pediatrica

    pub_type: 杂志文章

    doi:

    authors: Pellegrino M,D'Altilia MR,Lotti F,Andriani MG,Lelli-Chiesa PL,Jasonni V

    更新日期:1991-06-01 00:00:00

  • Risk factors for intubation in severe bronchiolitis: a useful tool to decide on an early intensive respiratory support.

    abstract:BACKGROUND:Bronchiolitis is the most frequent lower airway infection leading hospitalization in children younger than 2 years. RSV is the typical common cause, followed by rhinovirus. Criteria for Pediatric Intensive Care Unit (PICU) admission are not defined by guidelines. METHODS:A retrospective analysis of children...

    journal_title:Minerva pediatrica

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    doi:10.23736/S0026-4946.20.05574-7

    authors: Colombo J,Gattoni C,Carobbio A,Nacoti M,Pellicioli I,Vedovati S,Bonanomi E

    更新日期:2020-06-02 00:00:00

  • [Organisational aspects of a donated breast milk bank: experience of the Treviso hospital].

    abstract:AIM:This study analyses the organisational aspects and the volume of milk managed by the donated breast milk bank (banca del latte umano donato, BLUD) in Treviso. METHODS:The data gathered refer to the years 2003, 2004 and 2005. In particular the hygiene methodology is described in order to obtain a high-quality produ...

    journal_title:Minerva pediatrica

    pub_type: 杂志文章

    doi:

    authors: Paccagnella A,Michieletto S,Pitassi I,Baruffi C,Pizzolato D,Marcon ML,Saia OS,Toscani P,Moretti G,Foscolo G

    更新日期:2007-08-01 00:00:00

  • Complete clinical recovery of a central pontine and extrapontine myelinolysis delayed onset in a child with acute myeloblastic leukemia.

    abstract::Central pontine myelinolysis (CPM) is a demyelinating disease of the pons often associated with the demyelination of extrapontine areas of the central nervous system. It typically occurs 0.5-7 days after a rapid increment in serum Na level in hyponatremic patients and may lead to death. A 2.5-year-old child with a dia...

    journal_title:Minerva pediatrica

    pub_type: 杂志文章

    doi:

    authors: Yilmaz D,Karapinar B,Balkan C,Ay Y,Kavakli K

    更新日期:2011-02-01 00:00:00

  • [Late clinical manifestations of hydrocephalus associated with aqueductal stenosis].

    abstract::Hydrocephalus associated with aqueductal stenosis is not uncommon after the 2nd year of life. In some patients, stenosis is due to slow-growing periaqueductal tumors that can only be revealed by magnetic resonance examination. We reviewed 31 cases of children with aqueductal stenosis and hydrocephalus diagnosed after ...

    journal_title:Minerva pediatrica

    pub_type: 杂志文章

    doi:

    authors: Di Rocco C,Iannelli A,Tamburrini G

    更新日期:1995-12-01 00:00:00

  • Pharmacological strategies in the idiopatic pulmonary fibrosis of children.

    abstract::Idiopathic pulmonary fibrosis is characterized by radiographically evident interstitial infiltrates and progressive dyspnea with rapid decline of overall lung functions. The clinical course of this disease is highly variable; however, its prognosis remains poor without adequate and prompt therapeutical support. Due to...

    journal_title:Minerva pediatrica

    pub_type: 杂志文章,评审

    doi:

    authors: Rigante D,Stabile A

    更新日期:2004-04-01 00:00:00

  • Ventilator associated pneumonia due to carbapenem resistant microorganisms in children.

    abstract:BACKGROUND:Infections due to carbapenem resistant pathogens have become a major health threat especially for hospitalized patients. Acinetobacter baumanii (AB) and Pseudomonas aeruginosa (PA) are important pathogens causing ventilator-associated pneumonia (VAP) with a trend of high resistance to carbapenems. The aim of...

    journal_title:Minerva pediatrica

    pub_type: 杂志文章

    doi:10.23736/S0026-4946.17.04284-0

    authors: Kara SS,Polat M,Tapisiz A,Kalkan G,Simsek H,Tezer H

    更新日期:2019-08-01 00:00:00

  • Chronic hemodialysis in pediatric patients: technical and practical aspects of use.

    abstract::Chronic kidney disease (CKD) is a continuum of progressive reduction in kidney function lasting for more than three months, due to either structural and/or functional renal abnormalities that may lead to irreversible kidney damage. The term "renal supportive therapy" (RST) generally characterizes the spectrum of dialy...

    journal_title:Minerva pediatrica

    pub_type: 杂志文章,评审

    doi:

    authors: Harshman LA,Neuberger ML,Brophy PD

    更新日期:2012-04-01 00:00:00

  • [Critical comparison of some questionnaires for the evaluation of the quality of life in children affected by asthma].

    abstract:AIM:The aim of this study was to critically compare 9 different questionnaires for the evaluation of the Quality of Life in children affected by asthma. METHODS:The questionnaires were analyzed by considering their psychometric characteristics (reliability, validity, responsiveness, least clinically relevant differenc...

    journal_title:Minerva pediatrica

    pub_type: 杂志文章

    doi:

    authors: Rocchi MB,Bellagamba S

    更新日期:2003-08-01 00:00:00

  • Urinary zearalenone levels in girls with premature thelarche and idiopathic central precocious puberty.

    abstract:AIM:Recently, it was reported that the development of breast tissue and secondary sex characteristics in girls occurred at much younger age and the incidences of premature thelarce (PT) and central idiopathic precocious puberty (ICPP) are increasing. In this context, we wanted to evaluate the mycoestrogen exposure as t...

    journal_title:Minerva pediatrica

    pub_type: 杂志文章

    doi:

    authors: Asci A,Durmaz E,Erkekoglu P,Pasli D,Bircan I,Kocer-Gumusel B

    更新日期:2014-12-01 00:00:00

  • Effect of liposomes, vitamins A and E nasal spray in reducing the healing time after septoplasty with concurrent turbinate surgery in adolescents.

    abstract:BACKGROUND:This study evaluates endoscopic and quality of life (QoL) outcomes in two groups, composed by both allergic (A) and non-allergic (N-A) adolescents undergoing septoplasty with concurrent turbinate surgery by radiofrequency treated after surgery with nasal spray containing liposomes and vitamins A and E. METH...

    journal_title:Minerva pediatrica

    pub_type: 杂志文章,随机对照试验

    doi:10.23736/S0026-4946.16.04600-4

    authors: Ricciardiello F,Cantone E,Abate T,DI Lullo AM,Oliva F,Iengo M,DE Bernardo G

    更新日期:2017-02-01 00:00:00

  • [Crystalline lactulose and oral preparations of micro-organisms for the treatment of chronic aspecific diarrhea in children. A controlled clinical study].

    abstract::Aspecific chronic diarrhea is one of the most common causes of protracted diarrhea in infancy. The pathology is characterised by an increased frequency of daily bowel movement with half-formed feces; it is not associated to malabsorption syndrome or enteric infections and appears to be correlated to an unbalanced diet...

    journal_title:Minerva pediatrica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Roggero P,Volpe C,Ceccatelli MP,Lambri A,Giuliani MG,Donattini T,Garavaglia MC,De Vincentiis A

    更新日期:1990-04-01 00:00:00

  • [Symptomatological patterns of infancy diseases. Presentation of a new Symptom Checklist].

    abstract:BACKGROUND:Recently it is often very frequent a request of specialist consultation for children with psychic discomfort expressed through somatic complaints and/or behavior disorders. The real meaning of these symptoms in terms of prognosis, is not clear; indeed they can be the first signs of a poor prognosis of develo...

    journal_title:Minerva pediatrica

    pub_type: 杂志文章

    doi:

    authors: Milone A,Viglione VA,Maestro S,Muratori F,Chilosi A,Mengheri L,Romano R

    更新日期:1998-09-01 00:00:00

  • [The growth of the low-birth-weight neonate: assessment at 3 years].

    abstract::Follow-up studies of low-birth-weight (LBW) neonates have shown a high incidence of growth failure in the first years of life. We evaluated the growth attainment (weight, length and head circumference) in 182 LBW neonates discharged from our Intensive Care Unit between 1982-84 and included in a 3 years follow-up progr...

    journal_title:Minerva pediatrica

    pub_type: 杂志文章

    doi:

    authors: Romagnoli C,Luciano R,Rizzo C,Alecci MC,Cafforio C,Pasquini R,Tortorolo G

    更新日期:1993-03-01 00:00:00

  • [Congenital hypothyroidism and development].

    abstract::The authors present the developmental outcome of 16 children with congenital hypothyroidism diagnosed by screening in the neonatal period, using the Brazelton and the Dubowitz scales in the newborn and the Griffiths scale subsequently. Results are compared with those of a control group assessed at 6 and 18 months usin...

    journal_title:Minerva pediatrica

    pub_type: 杂志文章

    doi:

    authors: Gouveia R,De Almeida V,Lobo Fernandes MJ,Lacerda N,Gomes Pedro J

    更新日期:1989-04-01 00:00:00

  • [Sport activity in children and adolescents: temperament and emotional traits].

    abstract:AIM:Aim of this study is to evaluate anxiety and temperament characteristics in developmental age subjects who practised agonistic sport (individual or team sports) in comparison with a sample group of subjects who practice no agonistic sports. METHODS:Sixty subjects aged from 10 to 16 years were enrolled in the study...

    journal_title:Minerva pediatrica

    pub_type: 杂志文章

    doi:

    authors: Mazzone L,Mugno D,Morales G,Genitori D'Arrigo V,Ruta L,Bianchini R

    更新日期:2004-02-01 00:00:00

  • [Pulmonary hypertension caused by a severe scoliosis. Description of a case].

    abstract:BACKGROUND:Pulmonary hypertension in childhood is uncommon. It can be idiopathic or secondary to other pathologies (cardiovascular, skeletric,...). CASE DESCRIPTION:We report on a 9 year old girl suffering from pulmonary hypertension due to severe dorso-lumbar scoliosis. CONCLUSIONS:We discuss the etiopathogenetic re...

    journal_title:Minerva pediatrica

    pub_type: 杂志文章

    doi:

    authors: Carta M,Giuffrè M,Meli F,Liotta A

    更新日期:1996-11-01 00:00:00

  • [Height percentiles of children at 6 to 11 years of age in the area of Lazio].

    abstract:BACKGROUND:In this paper we present growth height standards obtained by an auxological study on a primary school population of central Italy (Lazio), in the 1991-1992 and 1992-1993 school-years. METHODS:4,175 children were included in the study: 2,024 females and 2,151 males, aged from 6 to 11 years. The sampling rate...

    journal_title:Minerva pediatrica

    pub_type: 杂志文章

    doi:

    authors: Schwarzenberg TL,Loreti P,Sgricia S,Acconcia P,Tiberi R,Buffone MR,Coltellacci M

    更新日期:1997-04-01 00:00:00

  • Developmental and behavioral profile in a domestic adoptees sample: a new challenge for the pediatrician.

    abstract:BACKGROUND:The aim of this study is to investigate the changes of developmental and behavioral profile in a domestic adoptees sample. METHODS:Thirty-six domestic adoptive families were recruited, resulting in a sample of 39 children. Families were sent a general questionnaire for collecting data related to the childre...

    journal_title:Minerva pediatrica

    pub_type: 杂志文章

    doi:

    authors: Ferrara P,Cutrona C,Guadagno C,Amato M,Sbordone A,Sacco R,Bona G

    更新日期:2020-10-01 00:00:00

  • [Impact of cerebral palsy in patients discharged from neonatal intensive care units].

    abstract:AIM:The aim of this study was to assess the impact and the peculiarities of cerebral palsy (CP) in children discharged from our neonatal intensive care unit (NICU) from January 1998 to April 2004. METHODS:A total of 2 303 children were discharged from our NICU during this period and 1 912 were followed up for 1 year t...

    journal_title:Minerva pediatrica

    pub_type: 杂志文章

    doi:

    authors: Romeo DM,Scoto M,Conversano M,Romeo MG

    更新日期:2006-04-01 00:00:00

  • A starch, glycyrretinic, zinc oxide and bisabolol based cream in the treatment of chronic mild-to-moderate atopic dermatitis in children: a three-center, assessor blinded trial.

    abstract:BACKGROUND:Atopic dermatitis (AD) is a very common chronic inflammatory and eczematous skin condition characterized by flares and remissions. Skin barrier alteration or dysfunction is the most relevant patogenetic factor. Topical corticosteroids are the mainstay treatment of AD, especially during flare periods. The dai...

    journal_title:Minerva pediatrica

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.23736/S0026-4946.17.05015-0

    authors: Licari A,Ruffinazzi G,DE Filippo M,Castagnoli R,Marseglia A,Agostinis F,Puviani M,Milani M,Marseglia GL

    更新日期:2017-12-01 00:00:00

  • Early preventive interventions for adolescents exposed to a potentially traumatic event.

    abstract::The development and evaluation of early preventative interventions for individuals exposed to a potentially traumatic event (PTE) have been increasing in number and sophistication over the last decade. Evaluation of early interventions for individuals who are symptomatic several weeks after exposure to a PTE have been...

    journal_title:Minerva pediatrica

    pub_type: 杂志文章,评审

    doi:

    authors: Berkowitz SJ,Watson PJ,Brymer MJ

    更新日期:2011-06-01 00:00:00

  • Feeding disorders in infancy: an empirical study on mother-infant interactions.

    abstract:AIM:The objective of this paper is an empirical analysis of mother-infant feeding interactions through an observational instrument (Feeding Scale), which is applied to the videotape of a feeding session. METHODS:Three samples of mothers and their children have been examined (104 couples with children ranging in age fr...

    journal_title:Minerva pediatrica

    pub_type: 杂志文章,评审

    doi:

    authors: Lucarelli L,Ambruzzi AM,Cimino S,D'Olimpio F,Finistrella V

    更新日期:2003-06-01 00:00:00

  • A case of femoral-facial syndrome in a patient with autism spectrum disorders.

    abstract::The Femoral hypoplasia - unusual facies syndrome (FHUF) or Femoral - facial syndrome (FFS) was at first described in 1975. Up to now about 60 cases have been reported. According to our knowledge only 4 cases have had congenital central nervous system's malformations, furthermore the main stages of psychomotor developm...

    journal_title:Minerva pediatrica

    pub_type: 杂志文章

    doi:

    authors: Vecchio D,Salzano E,Vecchio A,Di Filippo T,Roccella M

    更新日期:2011-08-01 00:00:00

  • Qualitative and quantitative revaluation of specific learning disabilities: a multicentric study.

    abstract:BACKGROUND:Specific learning disabilities are disorders that affect the instrumental skills of academic learning, leaving intact the general intellectual functioning. It is possible to distinguish: dyslexia, dysorthography, dysgraphia, and dyscalculia. The diagnosis is made according to DSMV. The aim of this study is t...

    journal_title:Minerva pediatrica

    pub_type: 杂志文章

    doi:10.23736/S0026-4946.18.05036-3

    authors: Operto FF,Mazza R,Buttiglione M,Craig F,Frolli A,Pisano S,Margari L,Coppola G

    更新日期:2018-04-12 00:00:00

  • Prevalence and incidence of reactions to insect stings in children: a reappraisal.

    abstract:AIM:The prevalence of systemic reactions (SR) to Hymenoptera stings in children was estimated in values lower than 1% in early studies but much higher in recent surveys. We evaluated the current prevalence and the incidence of SR and large local reactions (LLR) to Hymenoptera stings in children in Italy. METHODS:The d...

    journal_title:Minerva pediatrica

    pub_type: 杂志文章

    doi:

    authors: Quercia O,Incorvaia C,Marseglia GL,Puccinelli P,Dell'albani I,Emiliani F,Frati F,Stefanini GF

    更新日期:2014-08-01 00:00:00

  • Neonatal outcomes of multiple versus single very preterm infants.

    abstract:BACKGROUND:Neonatal morbidity and mortality differ between very preterm infants that result from single and those that result from a multiple order pregnancy. The aim of our study was to assess and compare the neonatal morbidity and mortality of multiple versus single very preterm infants. METHODS:Obstetrical and neon...

    journal_title:Minerva pediatrica

    pub_type: 杂志文章

    doi:10.23736/S0026-4946.19.05592-0

    authors: Rocha G,Flor-De-Lima F,Machado AP,Guimaraes H,Hypertensive Disorders of Pregnancy Study Group.

    更新日期:2019-11-05 00:00:00

  • Efficacy and safety of a medical device in reducing nasal obstruction in allergic children.

    abstract:AIM:Despite the availability of a number of pharmacological options, relief of allergic rhinitis (AR) symptoms, especially nasal obstruction, is often limited and local and systemic adverse reactions are not infrequent. The main aim of the present pilot study was to provide subjective and objective evidence of the clin...

    journal_title:Minerva pediatrica

    pub_type: 杂志文章

    doi:

    authors: Passali D,Passali FM,Loglisci M,Cambi J,Bellussi LM

    更新日期:2015-06-01 00:00:00

  • Monitoring the trend of overweight children in Cremona (anni 1990-1998).

    abstract:AIM:To evaluate the trend of infantile obesity in the school-aged population of Cremona over time. METHODS:The weight and height of all children aged 6, 9 and 11 attending schools within the health district of Cremona were measured for 9 consecutive years (January 1990-March 1998), giving a total of 17,730 measurement...

    journal_title:Minerva pediatrica

    pub_type: 杂志文章

    doi:

    authors: Boldori L,Marelli A

    更新日期:2000-01-01 00:00:00

  • Low grade gliomas of childhood: the actual management.

    abstract::Low grade gliomas (LGG) are the most common brain tumors of childhood and adolescence, consisting of a mixed group of grade I and grade II neoplasms. In general, their location and resectability are the most important predictors of outcome. Surgery is curative, usually for superficial tumors of the cerebral or cerebel...

    journal_title:Minerva pediatrica

    pub_type: 杂志文章

    doi:

    authors: Lober RM

    更新日期:2013-04-01 00:00:00