Abstract:
BACKGROUND:Neonatal morbidity and mortality differ between very preterm infants that result from single and those that result from a multiple order pregnancy. The aim of our study was to assess and compare the neonatal morbidity and mortality of multiple versus single very preterm infants. METHODS:Obstetrical and neonatal data on mothers and preterm infants with gestational ages between 24 and 30 weeks, born during 2015 and 2016 at 11 level III perinatal centers after a surveilled pregnancy, were analyzed and compared. Statistical analysis was performed using IBM SPSS® statistics 25 and a p-value < 0.05 was considered statistically significant. RESULTS:A total of 494 infants delivered from 410 women were enrolled in the study; 320 (64.8%) infants resulted from single gestation and 174 (35.2%) resulted from multiple order gestation (double=153, triple=21). Multiples were associated with a higher maternal age, a greater use of medically assisted reproduction techniques, higher C- section rates, more frequent full cycle use of antenatal corticosteroids, higher gestational age with adequate birth weight, spent less days on oxygen therapy, presented less prevalence of BPD and cPVL, needed less surgical closure of PDA and had a lower length of stay in NICU. Abruptio placenta, hypertensive disorders of pregnancy and preeclampsia were more frequent in single pregnancies. The multivariate analysis by logistic regression adjusted to gestational age and confounding variables did not show any significant difference on the outcomes of multiples compared to singles. CONCLUSIONS:The results of our study support the scientific evidence that, with the current practices, the neonatal morbidity and mortality of very premature infants are not different between those resulting from single and multiple gestations.
journal_name
Minerva Pediatrjournal_title
Minerva pediatricaauthors
Rocha G,Flor-De-Lima F,Machado AP,Guimaraes H,Hypertensive Disorders of Pregnancy Study Group.doi
10.23736/S0026-4946.19.05592-0subject
Has Abstractpub_date
2019-11-05 00:00:00eissn
0026-4946issn
1827-1715pii
S0026-4946.19.05592-0pub_type
杂志文章abstract::Eosinophilic esophagitis (EoE) is a chronic disease characterized by symptoms related to esophageal dysfunction and eosinophil-predominant inflammation (≥15 eosinophils/high power field). In the last ten years, several epidemiological studies showed a significant increase in the incidence and prevalence of EoE, especi...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:10.23736/S0026-4946.20.05913-7
更新日期:2020-10-01 00:00:00
abstract::Cystic fibrosis (CF) is a genetic disease associated with recurrent lung infections, that represent a major cause of mortality and morbidity. Cystic fibrosis requires frequent antibiotic treatments, sometimes by mouth or via aerosol but often via the intravenous route. Totally implanted venous access devices (ports) a...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2009-10-01 00:00:00
abstract::Noonan syndrome (NS) is a rare genetic disorder, revealing autosomal dominant trait. It is a multiface condition that is characterized by a series congenital malformations including facial anomalies, postnatal growth retardation, webbing of the neck, pectus excavatum/carinatum, pulmonic stenosis and undescended testic...
journal_title:Minerva pediatrica
pub_type: 杂志文章,评审
doi:
更新日期:2008-06-01 00:00:00
abstract:BACKGROUND:Acute gastroenteritis is responsible for dehydration in many children. The viruses like rotavirus, norovirus, and adenovirus are considered the main causative agents of gastroenteritis. The goal of this study is the evaluation of the symptoms, clinical findings and hospitalization requirements in pediatric p...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:10.23736/S0026-4946.16.04259-X
更新日期:2018-04-01 00:00:00
abstract::Bacterial meningitis is an infection of the central nervous system involving quite a number of neurological sequelae the most common of which is hearing impairment. To assess the incidence of audiological deficit the authors evaluated retrospectively 20 patients, between 4 months and 11 years of age, observed at the P...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:1995-10-01 00:00:00
abstract:AIM:Pectus excavatum is the commonest thoracic congenital malformation, but its treatment remains not well known. The authors present the results of the mini-invasive repair at G. Gaslini Institute of Genoa, Italy. METHODS:Nuss mini-invasive repair avoids anterior scars. The correction is achieved by the introduction ...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2008-08-01 00:00:00
abstract:AIM:The aim of this study was to critically compare 9 different questionnaires for the evaluation of the Quality of Life in children affected by asthma. METHODS:The questionnaires were analyzed by considering their psychometric characteristics (reliability, validity, responsiveness, least clinically relevant differenc...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2003-08-01 00:00:00
abstract:BACKGROUND:The aim of this study was to investigate the potential of dexfenfluramine (dF) for reducing cardiovascular risk factors and improving compliance towards diet in a group of young patients hospitalized for essential obesity of high degree (BMI > or = 35). METHODS:103 adolescents (mean age 15.4 +/- 0.2) partic...
journal_title:Minerva pediatrica
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1997-03-01 00:00:00
abstract:: ...
journal_title:Minerva pediatrica
pub_type: 信件
doi:10.23736/S0026-4946.17.04790-9
更新日期:2019-10-01 00:00:00
abstract:BACKGROUND:The aim of this study was to evaluate the lifestyle based on the physical activity and eating habits of young athletes. METHODS:In order to measure physical activity and eating habits in young people, 922 young athletes between the ages of 8 to 18 have been analyzed in this study. The participants were all ...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:10.23736/S0026-4946.16.04340-1
更新日期:2017-12-01 00:00:00
abstract::The paper reports five cases of Kawasaki's syndrome diagnosed during the period 1985-89. The mean age of patients was 20 months (4/12; 4 years and 5/12). Symptomatology gradually regressed in four of these patients with a return to good health and normal cardiological controls. The fifth patient died suddenly followin...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:1991-11-01 00:00:00
abstract::Certain humoral and cellular immunological parameters were assessed in patients with either pure atopic dermatitis or dermatitis combined with asthma in order to discover if there were any significant differences between the two clinical forms. The study was conducted on 15 children of both sexes who were investigated...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:1989-05-01 00:00:00
abstract::The management of neonatal fungal infections poses several challenges, including the fact that the choices of available agents are limited, given the paucity of data relating to the use of newer antifungal agents in the group of infants. The information summarized herein represents in part the consensus of a group of ...
journal_title:Minerva pediatrica
pub_type: 共识发展会议,杂志文章,评审
doi:
更新日期:2010-02-01 00:00:00
abstract:AIM:Promoting physical activity is one of the main goals of health-promotion policies. The period of adolescence is characterised by a high rate of abandonment of any physical activity. In this age range, moreover, the risk of assuming substances in order to improve muscular-mass or athletic results is concrete. This s...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2004-06-01 00:00:00
abstract:AIM:The estimation of peak expiratory flow (PEF) in children is a very easy and practical way to check lung function and helps in the diagnosis, treatment follow-up and evaluation of the development of chronic obstructive pulmonary disease. METHODS:Using a Mini-Wright flowmeter (Clement Clarke International Ltd, Engla...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2005-04-01 00:00:00
abstract::The dominant cause of mortality, morbidity and hospitalization worldwide is cardiac complications, and are the major public health problem in adult populations. The worldwide research is being focused on the idea that cardiovascular disease is an early life pathological state. Early unfavorable exposures, acting in di...
journal_title:Minerva pediatrica
pub_type: 杂志文章,评审
doi:10.23736/S0026-4946.16.04713-7
更新日期:2017-06-01 00:00:00
abstract:BACKGROUND:Although the main treatments of inflammatory bowel disease (IBD) aim at the induction and maintenance of clinical remission, several studies have demonstrated inflammation still present in clinical remission. The goal of this study was to analyze the gene expression profiles between the pediatric IBD and con...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:10.23736/S0026-4946.18.04997-6
更新日期:2018-01-29 00:00:00
abstract:AIM:The objective of this paper is an empirical analysis of mother-infant feeding interactions through an observational instrument (Feeding Scale), which is applied to the videotape of a feeding session. METHODS:Three samples of mothers and their children have been examined (104 couples with children ranging in age fr...
journal_title:Minerva pediatrica
pub_type: 杂志文章,评审
doi:
更新日期:2003-06-01 00:00:00
abstract::One of the principal duties of a staff nurse working in a NICU is the assistance of the ventilated infants. The management of the endotracheal tube is a key moment in the neonatal care and it is fundamental to prevent the ventilator induced lung injury and the change in the perfusion (especially in the brain) that may...
journal_title:Minerva pediatrica
pub_type: 杂志文章,评审
doi:
更新日期:2010-06-01 00:00:00
abstract::Gilbert's syndrome is a genetically controlled non-hemolytic unconjugated hyperbilirubinemia, caused by reduced activity of UDP-glucoroniltransferase 1, an enzyme critical in bilirubin metabolism. Several molecular configurations may be implicated in a Gilbert's phenotype. Familial mediterranean fever (FMF) is an inhe...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2008-08-01 00:00:00
abstract::Asthma is a condition characterised by airways inflammation and bronchial hyperresponsiveness to specific and aspecific spasmogens associated with reversible airways obstruction. The bronchomotor tone is the result of an interaction between neurotransmitter release and local mediators. The efferent neurohumoral pathwa...
journal_title:Minerva pediatrica
pub_type: 杂志文章,评审
doi:
更新日期:2000-11-01 00:00:00
abstract::Some reports have been published concerning the positive effects of using intravenous immunoglobulins as immunotherapy and immunoprophylaxis of infection in newborns. The safety and efficacy of intravenously administered gamma globulins 7S versus 5S was evaluated in 64 high-risk neonates. The infants admitted to this ...
journal_title:Minerva pediatrica
pub_type: 临床试验,杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::Hydrocephalus associated with aqueductal stenosis is not uncommon after the 2nd year of life. In some patients, stenosis is due to slow-growing periaqueductal tumors that can only be revealed by magnetic resonance examination. We reviewed 31 cases of children with aqueductal stenosis and hydrocephalus diagnosed after ...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:1995-12-01 00:00:00
abstract::In the present study the authors investigated the normal range of the marker TPA in the sera of 100 children (apparently healthy) aged from 0 to 6 years. Well-defined criteria as guide-lines to the interpretation of laboratory results are a very urgent necessity for the expanding utilization of clinical laboratory dat...
journal_title:Minerva pediatrica
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1994-11-01 00:00:00
abstract:BACKGROUND:The objective of this study was to define the distribution of inhalant allergens in pediatric patients in whom sensitization was diagnosed with a skin prick test (SPT) who had presented with allergic complaints. In addition, the correlation between the inhalant allergens detected on the SPT and the patients'...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2016-08-01 00:00:00
abstract:BACKGROUND:The aim of the present study is to investigate the suicide and attempted suicide phenomenon among young people (<25 years old) in the Verbano-Cusio-Ossola province from January 1988 to December 2000. METHODS:This epidemiological-descriptive survey is based on the acquisition of data through the examination ...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2003-04-01 00:00:00
abstract:AIM:Considering how eating habits affect the health of children and taking into account the influence of advertising messages, we wanted to investigate the quantity and the typology of advertising on air during children's television programmes. METHODS:The research was conducted beginning in January 2008 up to March 2...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2012-02-01 00:00:00
abstract:BACKGROUND:COVID-19 has quickly become a worldwide threat to health, travel, and commerce. Studies adressing the clinical-functional presentation of viral infection and physiotherapy management in children are scarce. The purpose statement was to provide current perspectives on the physiotherapy interventions for manag...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:10.23736/S0026-4946.20.06100-9
更新日期:2020-10-27 00:00:00
abstract:BACKGROUND:A complex association has been observed between birth weight (BW) and depression/anxiety symptoms at various stages of life. The purpose of this study was to evaluate whether adolescents with low or insufficient BW were more likely to report depressive/anxiety symptoms. METHODS:A cross-sectional study was c...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:10.23736/S0026-4946.17.04452-8
更新日期:2018-10-01 00:00:00
abstract::In a short girl with celiac disease and Hashimoto's thyroiditis (HT), suspicion of an associated pituitary lesion was suggested by the finding of a thyroid function pattern that was not compatible with HT-related hypothyroidism (low FT4 with normal TSH). This case report reinforces the view that the finding of a norma...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2016-04-01 00:00:00