Abstract：
:Low grade gliomas (LGG) are the most common brain tumors of childhood and adolescence, consisting of a mixed group of grade I and grade II neoplasms. In general, their location and resectability are the most important predictors of outcome. Surgery is curative, usually for superficial tumors of the cerebral or cerebellar hemispheres, but has a more controversial role for deep-seated midline tumors. Where gross total resection is not feasible, LGG becomes a chronic disease of childhood, and adjuvant therapies must be tailored for each individual based on age and tumor location. Radiotherapy (RT) is effective but associated with neurological, cognitive, and endocrinological morbidity, prompting the use of chemotherapy regimens aimed at delaying RT, especially in younger children. Long-term surveillance imaging for up to five years after treatment is warranted even after gross total resection, and lifelong surveillance is warranted after RT because of iatrogenic effects. Despite a favorable prognosis for survival, LGG are associated with disability, decreased quality of life, and late effects of treatment, all requiring long-term specialty care through a multidisciplinary approach.
journal_name
Minerva Pediatrjournal_title
Minerva pediatricaauthors
Lober RMsubject
Has Abstractpub_date
2013-04-01 00:00:00pages
149-65issue
2eissn
0026-4946issn
1827-1715pii
R15133914journal_volume
65pub_type
杂志文章abstract：INTRODUCTION:Chronic rhinosinusitis (CRS) is defined as an inflammatory disorder of the paranasal sinuses and of the nasal mucosa that lasts 12 weeks or longer. In CRS microbes contribute to the disease pathogenesis. Clinical microbiology is focused on finding single pathogens that causes the disease and the main goal ...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：10.23736/S0026-4946.20.05850-8
更新日期：2020-07-29 00:00:00
abstract：:The diagnosis and treatment of anorexia nervosa (AN) in children and adolescents has some commonality but also differs from that of this condition in adults. A new understanding of AN is emerging: research data from the fields of epidemiology, genetics, and brain biology, suggest that there may be an underlying brain ...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2013-02-01 00:00:00
abstract：AIM:The neurofibromatosis type 1 (NF1) is an autosomal dominant neurocutaneous disease. In 40-70% of cases are described signal hyperintensity on MRI, called unidentified bright objects (UBO). Their correlation with clinical disorders is still debated. The present study investigated the correlation between the UBOs and...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2013-08-01 00:00:00
abstract：:A case of phakomatosis pigmentovascularis type IIa in a, short stature, 6-year old girl with nevus flammeus of the face and palate, bilateral ocular melanosis, aberrant mongolian spots and minor dysmorphic traits is reported. The patient has been considered at risk for glaucoma and ocular melanoma and an ophthalmologi...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：1996-05-01 00:00:00
abstract：BACKGROUND:The aim of this study was to determine serum pancreatic stone protein (PSP) levels in the neonates with highly probable or probable sepsis and assess their possible value in predicting infected neonates. METHODS:This was a prospective study involving 119 neonates who were admitted with suspected sepsis. The...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：10.23736/S0026-4946.16.04317-X
更新日期：2017-12-01 00:00:00
abstract：BACKGROUND:Neonatal hypoxic-ischemic encephalopathy is still a significant cause of neonatal death and neurodevelopmental disabilities, such as cerebral palsy, mental delay, and epilepsy. After the introduction of therapeutic hypothermia, the prognosis of hypoxic-ischemic encephalopathy has improved, with reduction of ...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：10.23736/S0026-4946.18.05224-6
更新日期：2018-07-02 00:00:00
abstract：:Congenital diaphragmatic hernia (CDH) remains one of the major challenges in neonatal surgery. Survival rate has increased in the last decades mainly due to perinatal care and surgical technique improvements. Classically, a laparotomy has been performed after cardiovascular and respiratory stabilization. Introduction ...
journal_title：Minerva pediatrica
pub_type： 杂志文章,评审
doi：10.23736/S0026-4946.17.05110-6
更新日期：2018-06-01 00:00:00
abstract：:Certain humoral and cellular immunological parameters were assessed in patients with either pure atopic dermatitis or dermatitis combined with asthma in order to discover if there were any significant differences between the two clinical forms. The study was conducted on 15 children of both sexes who were investigated...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：1989-05-01 00:00:00
abstract：:With the cooperation of 12 Maternity Hospitals we have started a prospective study to evaluate the effect of dietary and environmental measures in the development of atopic disease in "at risk" newborns. The preventive measures included: exclusive breast feeding for the first 6 months of life, soy milk supplement when...
journal_title：Minerva pediatrica
pub_type： 杂志文章,多中心研究,评审
doi：
更新日期：1996-10-01 00:00:00
abstract：:The management of neonatal fungal infections poses several challenges, including the fact that the choices of available agents are limited, given the paucity of data relating to the use of newer antifungal agents in the group of infants. The information summarized herein represents in part the consensus of a group of ...
journal_title：Minerva pediatrica
pub_type： 共识发展会议,杂志文章,评审
doi：
更新日期：2010-02-01 00:00:00
abstract：:Splenic infarction has been associated with haematologic and tromboembolic disorders and, more rarely, with infectious diseases. A case of splenic infartion during an attack of brucellosis is reported. Symptoms included persistent left upper quadrant pain and fever. An abdomen scan confirmed the presence of a triangul...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2001-12-01 00:00:00
abstract：AIM:Recently, it was reported that the development of breast tissue and secondary sex characteristics in girls occurred at much younger age and the incidences of premature thelarce (PT) and central idiopathic precocious puberty (ICPP) are increasing. In this context, we wanted to evaluate the mycoestrogen exposure as t...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2014-12-01 00:00:00
abstract：:The care of adolescents suffering from high risk disease is a demanding challenge. At times, adolescents may well be too old for the pediatrician and Pediatric Units, and yet too young for the adult practitioner. A dedicated approach that builds on the insight deriving from special attention to, and reflection on the ...
journal_title：Minerva pediatrica
pub_type： 社论
doi：
更新日期：2011-04-01 00:00:00
abstract：:With increased survival of extremely low birth weigh (ELBW) and very ill infants, a lot of them are discharged with unresolved medical issues that complicate their subsequent care. Infants born preterm with low birth weight who require neonatal intensive care experience a much higher rate of hospital readmission and d...
journal_title：Minerva pediatrica
pub_type： 杂志文章,评审
doi：
更新日期：2010-06-01 00:00:00
abstract：:Joint hypermobility refers to the ability that a joint has to move beyond its normal range of motion. It is common in the general population, particularly in children. While many individuals manifesting joint hypermobility are healthy, this feature can accompany a wide range of symptoms and systemic disorders, whose m...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：10.23736/S0026-4946.20.05766-7
更新日期：2020-04-01 00:00:00
abstract：:The association of congenital anal stenosis, or other anal and rectal malformation, sacral defect and a presacral mass is known as the Currarino syndrome described for the first time in 1981. Currarino et al. proposed that abnormal endoectodermal adhesions and notochordal defects in early fetal life may result in a fi...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2005-06-01 00:00:00
abstract：:Between 1973 and 1993 7 perineal testis are observed and operated on in our surgical department. The perineal testis is a rare ectopic testis probably caused by some mechanical obstacles in the entrance of the testis in the scrotum. A diagnosis is easy if also the less frequent localizations of testicular ectopia are ...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：1993-11-01 00:00:00
abstract：AIM:Promoting physical activity is one of the main goals of health-promotion policies. The period of adolescence is characterised by a high rate of abandonment of any physical activity. In this age range, moreover, the risk of assuming substances in order to improve muscular-mass or athletic results is concrete. This s...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2004-06-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to asses the validity of the TCB nomogram for the European population for predicting significant hyperbilirubinemia in healthy term and late-preterm newborns. METHODS:This observational study was conducted from February 2009 to December 2009 in the well-baby nurseries of Gemelli hos...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2010-06-01 00:00:00
abstract：AIM:To evaluate the prevalence of ultrasound diagnosis of adenomyosis and endometriosis in young women complaining of pelvic pain and to find the symptoms and clinical characteristics associated with these diseases in young women. METHODS:Cross-sectional study, including 100 young women (14-24 years) with a history of...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：10.23736/S0026-4946.20.05842-9
更新日期：2020-06-16 00:00:00
abstract：:The present study concerns with anthropometric and nutritional data collected in the school population of a small rural town in Lazio. We studied 368 school-children of both sexes, belonging to the following age groups: from 7 to 8 years, 9 to 10 years, 11 to 12 years, 13 to 14 years. The technique of evaluation of ob...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：1992-06-01 00:00:00
abstract：:Heart failure can be defined as the inability of the heart to sufficiently support the circulation. In the fetus, heart failure can be caused by a myriad of factors that include fetal shunting abnormalities, genetic cardiomyopathies, extracardiac malformations, arrhythmias and structural congenital heart disease. With...
journal_title：Minerva pediatrica
pub_type： 杂志文章,评审
doi：
更新日期：2012-10-01 00:00:00
abstract：:A preliminary undiagnosed case of partial carbamyl-phosphate-synthetase deficiency in a 14 year old patient is described. This extremely rare metabolic disorder is unlikely to produce clinical symptoms at such an advanced age. Details are given of the clinical picture, the diagnosis (by liver biopsy and post mortem li...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：1989-02-01 00:00:00
abstract：BACKGROUND:To evaluate if vesicoureteral reflux (VUR) contralateral to the multicystic dysplastic kidney can interfere with the compensatory renal hypertrophy. METHODS:Twenty-seven patients (17 males, 10 females) with multicystic dysplastic kidney (MDK) (14 on the right, 13 on the left) have been treated at the Nephro...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2001-04-01 00:00:00
abstract：:The authors report 3 cases of cytochrome-c-oxidase deficiency (2 cases of Kearns-Sayre syndrome and 1 case of chronic progressive external ophthalmoplegia) with Central Nervous System alterations and facial anomalies. The facial anomalies are high forehead, wide nasal bridge, upturned nose, long and flat philtrum (alt...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2004-10-01 00:00:00
abstract：BACKGROUND:This study evaluates endoscopic and quality of life (QoL) outcomes in two groups, composed by both allergic (A) and non-allergic (N-A) adolescents undergoing septoplasty with concurrent turbinate surgery by radiofrequency treated after surgery with nasal spray containing liposomes and vitamins A and E. METH...
journal_title：Minerva pediatrica
pub_type： 杂志文章,随机对照试验
doi：10.23736/S0026-4946.16.04600-4
更新日期：2017-02-01 00:00:00
abstract：:West syndrome is a generalized epilepsy syndrome composed of infantile spasms and onset is usually within the first year of life. Although West syndrome is well known clinical epileptic syndrome, there is no agreement about the first- and second-line treatments. In the last years a great progress in the development of...
journal_title：Minerva pediatrica
pub_type： 杂志文章,评审
doi：
更新日期：2007-06-01 00:00:00
abstract：BACKGROUND:Atopic dermatitis (AD) is a very common chronic inflammatory and eczematous skin condition characterized by flares and remissions. Skin barrier alteration or dysfunction is the most relevant patogenetic factor. Topical corticosteroids are the mainstay treatment of AD, especially during flare periods. The dai...
journal_title：Minerva pediatrica
pub_type： 临床试验,杂志文章,多中心研究
doi：10.23736/S0026-4946.17.05015-0
更新日期：2017-12-01 00:00:00
abstract：AIM:Optic pathway gliomas (OPG) are the predominant intracranial tumours associated with neurofibromatosis type 1 (NF1). The aim of this study was to evaluate the prevalence and the outcome of OPG in 200 NF1 patients (122 males and 78 females, aged 1-25 years) followed up to 16 years (mean of 6 years). METHODS:All chi...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2007-02-01 00:00:00
abstract：:Central pontine myelinolysis (CPM) is a demyelinating disease of the pons often associated with the demyelination of extrapontine areas of the central nervous system. It typically occurs 0.5-7 days after a rapid increment in serum Na level in hyponatremic patients and may lead to death. A 2.5-year-old child with a dia...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2011-02-01 00:00:00
