Abstract：
BACKGROUND:The aim of this study was to determine serum pancreatic stone protein (PSP) levels in the neonates with highly probable or probable sepsis and assess their possible value in predicting infected neonates. METHODS:This was a prospective study involving 119 neonates who were admitted with suspected sepsis. The study population was divided into two groups, a infected group (N.=40, with highly probable sepsis or probable sepsis) and control group (N.=79, with possible or no sepsis). The blood samples were obtained at 24, 72 and 168 hours after birth. The amount of serum PSP were detected by enzyme linked immunosorbent (ELISA). RESULTS:PSP serum concentrations were higher in the infected group comparison to the control group at all time points (all P=0.000). In addition the sequential comparison between the infected group and control group at all of time points was significantly different (F=48.558, P=0.000). ROC area under the curve (AUC) was 0.791 [95% CI: 0.71-0.87; P=0.000] for PSP at 24 hours after birth and 0.790 (95% CI: 0.79-0.88; P=0.000) 72 hours after birth and combination of the two time points (24 and 72 hours), the AUC was 0.819 (95% CI: 0.74-0.90; P=0.000). CONCLUSIONS:PSP is a valuable biomarker in predicting infected neonates. Combination of PSP at each time point within 72 hours after birth might be better.
journal_name
Minerva Pediatrjournal_title
Minerva pediatricaauthors
Wu R,Zha L,Hu JH,Wu JM,Tian ZFdoi
10.23736/S0026-4946.16.04317-Xsubject
Has Abstractpub_date
2017-12-01 00:00:00pages
489-494issue
6eissn
0026-4946issn
1827-1715pii
R15Y9999N00A16031702journal_volume
69pub_type
杂志文章abstract：:Idiopathic pulmonary fibrosis is characterized by radiographically evident interstitial infiltrates and progressive dyspnea with rapid decline of overall lung functions. The clinical course of this disease is highly variable; however, its prognosis remains poor without adequate and prompt therapeutical support. Due to...
journal_title：Minerva pediatrica
pub_type： 杂志文章,评审
doi：
更新日期：2004-04-01 00:00:00
abstract：:Pharmacological profile of broxaterol, a new beta adrenergic compound, was investigated in 12 asthmatic children (6 male and 6 female with age 8-13 years). This study was performed from November to May, and venous blood was collected after 30, 45, 120, 180, 240 minutes from administration of 0.5 mg broxaterol; the uri...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：1992-09-01 00:00:00
abstract：AIM:To test the impact of a public health model to implement HIV pediatric care in Limited Resource Settings. METHODS:A retrospective study on the clinical files of 679 Mozambican children (mean age 4.4 years; SD 3.2), has been carried out. The pediatric patients received HAART (Highly Active Anti-Retroviral Therapy) ...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2006-10-01 00:00:00
abstract：:Avascular necrosis (AN) of bone is a complication of systemic lupus erythematosus (SLE). In the present paper we describe two patients with SLE who presented an AN of femoral condyles 18 months and 2 years respectively after the diagnosis of the disease. In the second case, together with the destructive change of the ...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：BACKGROUND:Specific learning disorders (SLDs) are a group of neuropsychological disorders which reduce a child's ability to read and/or write and/or use numbers. Internalizing disorders, and in particular anxiety, has been reported as a relatively common comorbidity in children with reading difficulties. We conducted t...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2016-02-01 00:00:00
abstract：AIM:The aim of this study was to evaluate the role of different techniques in the diagnostic workup of children with negative prenatal ultrasonogram, referred for urinary tract infection (UTI) within the first 24 months. METHODS:One-hundred and forty-seven patients, 71 males/76 females were studied. All patients were ...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2005-10-01 00:00:00
abstract：:The Femoral hypoplasia - unusual facies syndrome (FHUF) or Femoral - facial syndrome (FFS) was at first described in 1975. Up to now about 60 cases have been reported. According to our knowledge only 4 cases have had congenital central nervous system's malformations, furthermore the main stages of psychomotor developm...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2011-08-01 00:00:00
abstract：:Biliary atresia is a severe neonatal malformation in which the entire extrahepatic biliary tract or part of it is absent and replaced by fibrosclerotic tissue. Having been described for the first time by Thomson in 1891, biliary atresia has an incidence of 1:10,000-15,000 live neonates with a slight predominance in th...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2001-08-01 00:00:00
abstract：AIM:To verify the efficacy of botulinus toxin A (TB-A) in treating children with neuropathic bladder secondary to myelomeningocele (MMC) with detrusor hyperactivity/low compliance, resistance to pharmacological therapy, and candidates for enterocystoplasty. METHODS:From January 2002 to June 2003, a group of 7 patients...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2005-02-01 00:00:00
abstract：AIM:Macrophage activation syndrome (MAS) is a rare complication of childhood with rheumatic disease. This syndrome has been reported as a complication of many rheumatic diseases, most commonly in systemic onset of juvenile idiopathic arthritis (SoJIA). The aim of this study was evaluation the rate, symptoms and outcome...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2011-12-01 00:00:00
abstract：:Subjects suffering from bronchial asthma being treated with theophylline often have to be treated with an antibiotic during acute stages. The purpose of the present study is to assess to clearance variation in theophylline when a macrolide antibiotic is associated after theophyllinemia steady-state has been attained. ...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：1989-06-01 00:00:00
abstract：BACKGROUND:Obesity is a condition that increases the risk of developing several health problems, resulting in high health care costs worldwide. Therefore, it is important to investigate several avenues for the control of this condition. This study aimed to identify a dermatoglyphical condition that distinguishes obesit...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：10.23736/S0026-4946.20.05731-X
更新日期：2021-01-13 00:00:00
abstract：AIM:The objective of this paper is an empirical analysis of mother-infant feeding interactions through an observational instrument (Feeding Scale), which is applied to the videotape of a feeding session. METHODS:Three samples of mothers and their children have been examined (104 couples with children ranging in age fr...
journal_title：Minerva pediatrica
pub_type： 杂志文章,评审
doi：
更新日期：2003-06-01 00:00:00
abstract：:We report on a young patient who suffered from diabetes mellitus and neurosensorial deafness from the age of two. One year later she was noted to have deteriorated vision and the diagnosis of optic atrophy was made, her visual acuity decreased progressively. At the age of six she was admitted to our hospital because o...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：1995-04-01 00:00:00
abstract：:Noonan syndrome (NS) is a rare genetic disorder, revealing autosomal dominant trait. It is a multiface condition that is characterized by a series congenital malformations including facial anomalies, postnatal growth retardation, webbing of the neck, pectus excavatum/carinatum, pulmonic stenosis and undescended testic...
journal_title：Minerva pediatrica
pub_type： 杂志文章,评审
doi：
更新日期：2008-06-01 00:00:00
abstract：:With the cooperation of 12 Maternity Hospitals we have started a prospective study to evaluate the effect of dietary and environmental measures in the development of atopic disease in "at risk" newborns. The preventive measures included: exclusive breast feeding for the first 6 months of life, soy milk supplement when...
journal_title：Minerva pediatrica
pub_type： 杂志文章,多中心研究,评审
doi：
更新日期：1996-10-01 00:00:00
abstract：:In a short girl with celiac disease and Hashimoto's thyroiditis (HT), suspicion of an associated pituitary lesion was suggested by the finding of a thyroid function pattern that was not compatible with HT-related hypothyroidism (low FT4 with normal TSH). This case report reinforces the view that the finding of a norma...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2016-04-01 00:00:00
abstract：: ...
journal_title：Minerva pediatrica
pub_type： 社论
doi：10.23736/S0026-4946.18.05437-3
更新日期：2018-12-01 00:00:00
abstract：:Anti-endomysium antibodies (AEA) and Antigliadin antibodies (AGA) have been compared in a group of coeliac patients (17 with untreated coeliac disease, 56 after gluten free diet and 14 after gluten challenge), in 69 patients with various intestinal pathological conditions, and in 40 healthy children, in order to appre...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：:The lipidaemic profile has been evaluated in a series of 603 healthy children aged 13-14, within a programme for the prevention of atherosclerotic disease commenced in November 1980 at Health Unit 66 of the Region of Piedmont. Hyperlipaemia is among the environmental risk factors for ATS and more than any of the other...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：1991-07-01 00:00:00
abstract：BACKGROUND:The aim of the present trial is to determine the efficacy and safety profile of oxatomide, a potent antiallergic drug, in children aged under 2 years, suffering from atopic dermatitis. A comparison between 2 different dosage schemes was scheduled. METHODS:An oral suspension of oxatomide, in a neonatological...
journal_title：Minerva pediatrica
pub_type： 临床试验,杂志文章
doi：
更新日期：1997-12-01 00:00:00
abstract：BACKGROUND:This study aims to explore the correlation between nutrient level and pneumonia via the analysis and intervention of nutrient levels in pediatric patients with pneumonia. METHODS:Nutrient deficient children with pneumonia were randomized into intervention and non-intervention groups, and healthy children wi...
journal_title：Minerva pediatrica
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2016-02-01 00:00:00
abstract：BACKGROUND:Neonatal morbidity and mortality differ between very preterm infants that result from single and those that result from a multiple order pregnancy. The aim of our study was to assess and compare the neonatal morbidity and mortality of multiple versus single very preterm infants. METHODS:Obstetrical and neon...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：10.23736/S0026-4946.19.05592-0
更新日期：2019-11-05 00:00:00
abstract：BACKGROUND:The aim of this study was to analyze multidrug resistance-associated protein 1 (MRP1) expression of peripheral blood of children intractable epilepsy. METHODS:Sixty children with epilepsy admitted to outpatient and inpatient services of Xuzhou Children's Hospital between November 2010 and October 2011 were ...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：10.23736/S0026-4946.16.04358-9
更新日期：2018-04-01 00:00:00
abstract：:QT prolongation is rarely seen after acute stress reactions such as burn injury and severe head trauma. Although pathophysiologic mechanism is not entirely clear, acute stress is thought to contribute to the inhomogeneity of ventricular repolarization and it is hypothesized that QTc dispersion increases with severity ...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2006-12-01 00:00:00
abstract：BACKGROUND:Infections due to carbapenem resistant pathogens have become a major health threat especially for hospitalized patients. Acinetobacter baumanii (AB) and Pseudomonas aeruginosa (PA) are important pathogens causing ventilator-associated pneumonia (VAP) with a trend of high resistance to carbapenems. The aim of...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：10.23736/S0026-4946.17.04284-0
更新日期：2019-08-01 00:00:00
abstract：BACKGROUND:The aim of the present study is to investigate the suicide and attempted suicide phenomenon among young people (<25 years old) in the Verbano-Cusio-Ossola province from January 1988 to December 2000. METHODS:This epidemiological-descriptive survey is based on the acquisition of data through the examination ...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2003-04-01 00:00:00
abstract：:The management of neonatal fungal infections poses several challenges, including the fact that the choices of available agents are limited, given the paucity of data relating to the use of newer antifungal agents in the group of infants. The information summarized herein represents in part the consensus of a group of ...
journal_title：Minerva pediatrica
pub_type： 共识发展会议,杂志文章,评审
doi：
更新日期：2010-02-01 00:00:00
abstract：:The gynaecological approach with the adolescent is always complex, arduous and also stimulating. It is necessary to acquire specific knowledge, to understand that the adolescent is always searching for his identity and that the most important request is that the normality. The first impact is fundamental, understandin...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2002-12-01 00:00:00
abstract：:Cerebral palsy (CP) is a description of a spectrum of central nervous system (CNS) impairments that affect mobility, communication, intellectual ability, and neurobehavior as a result of developmental brain dysfunction. CP is the most common contributor to motor disability in children with prevalence of about 2-3/1000...
journal_title：Minerva pediatrica
pub_type： 杂志文章,评审
doi：
更新日期：2009-08-01 00:00:00
