Abstract:
AIM:To test the impact of a public health model to implement HIV pediatric care in Limited Resource Settings. METHODS:A retrospective study on the clinical files of 679 Mozambican children (mean age 4.4 years; SD 3.2), has been carried out. The pediatric patients received HAART (Highly Active Anti-Retroviral Therapy) in the framework of DREAM, a nationwide public health program offering an integrated model of care to HIV patients including free-of-charge HAART and monitoring, nutritional assessment and supplementation, peer-to-peer education, active tracing of the dropped out patients. RESULTS:HAART was started in 297 subjects out of 679. The median time of treatment was 286 (IQ 25-75:125-465). Mortality rate was lower in the sub-sample receiving HAART (8.4%; CI 95%: 5.2-11.6 vs 13.1%; CI 95%: 9.7-16.5). After 6 months of treatment the percentage of viral load lower than 400 copies/mL rose from 4.9% to 46.3%. The percentage of patients with less than 15% of CD4 cells out of the total lymphocyte count and the percentage of patients below the 2 z-score decreased from 56.4% and 58.1% to 8.8% and 38.1% respectively. CONCLUSIONS:Pediatric HAART in limited resource settings often face difficulties to handle complex treatment schemes, but the implemented model seems to be an effective tool to reduce mortality rate in HIV positive pediatric population.
journal_name
Minerva Pediatrjournal_title
Minerva pediatricaauthors
Marazzi MC,Germano P,Liotta G,Buonomo E,Guidotti G,Palombi Lsubject
Has Abstractpub_date
2006-10-01 00:00:00pages
483-90issue
5eissn
0026-4946issn
1827-1715journal_volume
58pub_type
杂志文章abstract::Parenteral nutrition associated liver disease is the most common complication of pediatric short bowel syndrome (SBS). There is emerging evidence that the disease may be reversed with the use of parenteral lipid emulsions derived from fish-oils, which contain significant concentrations of omega-3 fatty acids (w3FA). T...
journal_title:Minerva pediatrica
pub_type: 杂志文章,评审
doi:
更新日期:2009-06-01 00:00:00
abstract:AIM:To evaluate the prevalence of ultrasound diagnosis of adenomyosis and endometriosis in young women complaining of pelvic pain and to find the symptoms and clinical characteristics associated with these diseases in young women. METHODS:Cross-sectional study, including 100 young women (14-24 years) with a history of...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:10.23736/S0026-4946.20.05842-9
更新日期:2020-06-16 00:00:00
abstract:BACKGROUND:Inflammation may represent a common underlying mechanism in a wide range of diseases, including neuropsychiatric disorders. Cytokine involvement has been investigated in some studies on patients with childhood neuropsychiatric diseases. The aim of this study was to determine whether cytokines are involved in...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2016-12-22 00:00:00
abstract::The remarkable effectiveness of surfactant in neonatology suggested its use also in adults as well as in children on the basis of the pulmonary pathophysiology. We describe a case of an 18 month-old child affected by acute respiratory distress syndrome (ARDS) due to asphyxy by gastric juice inhalation, successfully tr...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2007-12-01 00:00:00
abstract::A case of phakomatosis pigmentovascularis type IIa in a, short stature, 6-year old girl with nevus flammeus of the face and palate, bilateral ocular melanosis, aberrant mongolian spots and minor dysmorphic traits is reported. The patient has been considered at risk for glaucoma and ocular melanoma and an ophthalmologi...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:1996-05-01 00:00:00
abstract::Asthma is a condition characterised by airways inflammation and bronchial hyperresponsiveness to specific and aspecific spasmogens associated with reversible airways obstruction. The bronchomotor tone is the result of an interaction between neurotransmitter release and local mediators. The efferent neurohumoral pathwa...
journal_title:Minerva pediatrica
pub_type: 杂志文章,评审
doi:
更新日期:2000-11-01 00:00:00
abstract::One may have only minutes to change the trajectory of a child who is deteriorating from either congenital or acquired cardiac disease. However, these children may present with rather cryptic patterns of symptoms (e.g. failure to thrive, lethargy, colic, neonatal shock, respiratory distress, wheezing and syncope with e...
journal_title:Minerva pediatrica
pub_type: 杂志文章,评审
doi:
更新日期:2009-04-01 00:00:00
abstract:BACKGROUND:Although the main treatments of inflammatory bowel disease (IBD) aim at the induction and maintenance of clinical remission, several studies have demonstrated inflammation still present in clinical remission. The goal of this study was to analyze the gene expression profiles between the pediatric IBD and con...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:10.23736/S0026-4946.18.04997-6
更新日期:2018-01-29 00:00:00
abstract:BACKGROUND:Recent developments regarding the conservative management of multicystic dysplastic kidney disease (MDKD) have shown a reduction in the well-established practice of elective surgical treatment. It has been seen that in the majority of cases the evolution of MDKD is either partial or complete atrophy. The inc...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:1997-05-01 00:00:00
abstract::Congenital diaphragmatic hernia (CDH) remains one of the major challenges in neonatal surgery. Survival rate has increased in the last decades mainly due to perinatal care and surgical technique improvements. Classically, a laparotomy has been performed after cardiovascular and respiratory stabilization. Introduction ...
journal_title:Minerva pediatrica
pub_type: 杂志文章,评审
doi:10.23736/S0026-4946.17.05110-6
更新日期:2018-06-01 00:00:00
abstract::This is the first scientific study on Mary Sandrucci, who has been director of the Pediatric Clinic of the University of Turin from 1965-1966 up to 31 December 1989. Prof. Sandrucci led major studies on congenital heart disease, was the first Italian and among the first in Europe to describe phocomelia cases, to repor...
journal_title:Minerva pediatrica
pub_type: 传,历史文章,杂志文章
doi:
更新日期:2011-04-01 00:00:00
abstract:AIM:Glioneuronal tumors (especially gangliogliomas and dysembryoplastic neuroepithelial tumors) are an increasingly recognised cause of drug-resistant epilepsy in children. The optimal surgical strategy (lesionectomy vs. extended resection of epileptogenic peritumoral areas) to obtain seizure control has not been fully...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2013-12-01 00:00:00
abstract::A study was carried out to characterize in the growing skeleton the absorptiometric measurement of the ultradistal radial epiphysis where the trabecular bone is higher than at proximal scanning planes. The study showed that a radius scan, 1 to 1.4 cm proximal to the ulnar tip, and consequently 4 to 6 mm proximal to th...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:1991-07-01 00:00:00
abstract:BACKGROUND:Bronchiolitis is the most frequent lower airway infection leading hospitalization in children younger than 2 years. RSV is the typical common cause, followed by rhinovirus. Criteria for Pediatric Intensive Care Unit (PICU) admission are not defined by guidelines. METHODS:A retrospective analysis of children...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:10.23736/S0026-4946.20.05574-7
更新日期:2020-06-02 00:00:00
abstract::Salmonella infections can manifest themselves as acute abdominal problems and lead to emergency surgery. Some examples are: salmonella-related intestinal perforations, gallbladder involments, salpingitis, and peritonitis. Mesenteric lymphadenitis associated with salmonella mimics acute appendicitis and it is often dif...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2006-04-01 00:00:00
abstract::This work aims at describing a particular case of Budd-Chiari syndrome in a ten-year-old girl. In our patient, the subjective and objective features of this disease, which is already rare during childhood, are associated with a well-assessed polyposis in the blind intestine (intestinum caecum). In our opinion, a possi...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:1995-06-01 00:00:00
abstract::Low grade gliomas (LGG) are the most common brain tumors of childhood and adolescence, consisting of a mixed group of grade I and grade II neoplasms. In general, their location and resectability are the most important predictors of outcome. Surgery is curative, usually for superficial tumors of the cerebral or cerebel...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2013-04-01 00:00:00
abstract::Post-traumatic stress disorder (PTSD) is a common psychiatric disorder which is frequently comorbid with major depressive disorder (MDD). It has been suggested that some or all individuals diagnosed with comorbid PTSD and MDD have a separate psychobiological condition that can be termed ''post-traumatic mood disorder'...
journal_title:Minerva pediatrica
pub_type: 杂志文章,评审
doi:
更新日期:2008-12-01 00:00:00
abstract::Intra-abdominal lymphangiomas are rare benign tumours that can cause various symptoms, mainly during childhood. They are diagnosed by ultrasonography, CT scanning or at laparotomy; ultrasonographic examination often shows a voluminous tumoral cystic formation with septa. The location of the cyst may be determined eith...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2006-02-01 00:00:00
abstract:BACKGROUND:This study aims to explore the correlation between nutrient level and pneumonia via the analysis and intervention of nutrient levels in pediatric patients with pneumonia. METHODS:Nutrient deficient children with pneumonia were randomized into intervention and non-intervention groups, and healthy children wi...
journal_title:Minerva pediatrica
pub_type: 杂志文章,随机对照试验
doi:
更新日期:2016-02-01 00:00:00
abstract::A survey was carried out within the framework of the Association of Hospital Pediatricians (APO) on the implementation of the pediatric structure in Pediatric hospitals wards in Piedmont during 1990. There was a 100% adhesion rate. It was found that only in 7 out of 36 hospitals were children always admitted to the Pe...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:1996-09-01 00:00:00
abstract::The usefulness of measuring xylosaemia, carotenaemia and the antigliadin antibodies in the diagnosis and monitoring of coeliac diseases has been examined, 89 children, 57 with aspecific chronic diarrhoea and 32 with coeliachia were examined. The xylose proved less sensitive (80%) and less specific (84.2%) than caroten...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:1989-09-01 00:00:00
abstract::Asthma therapy recognizes three fundamental key points: primary prevention, secondary prevention, including the control of inflammatory mechanisms and related symptoms, and tertiary prevention, consisting in the treatment of the early phases leading to airway remodelling. As for primary prevention in infants at ''high...
journal_title:Minerva pediatrica
pub_type: 杂志文章,评审
doi:
更新日期:2008-04-01 00:00:00
abstract::This study describes the blood pressure (BP), heart rate and weight distribution of 1214 school-age children (6-11 years old) in Messina. The systolic BP is significantly correlated with weight in every age and in both sexes. The incidence of BP values equal or above the 95 degrees percentile are significantly higher ...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:1990-04-01 00:00:00
abstract::Between 1973 and 1993 7 perineal testis are observed and operated on in our surgical department. The perineal testis is a rare ectopic testis probably caused by some mechanical obstacles in the entrance of the testis in the scrotum. A diagnosis is easy if also the less frequent localizations of testicular ectopia are ...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:1993-11-01 00:00:00
abstract:: ...
journal_title:Minerva pediatrica
pub_type: 信件
doi:10.23736/S0026-4946.19.05297-6
更新日期:2019-10-01 00:00:00
abstract::Testosterone, LH, FSH, blood levels at birth were determined in 40 Italian true cryptorchid , 12 pseudo-cryptorchid and 71 healthy newborns. Testosterone concentrations were interpreted according to the localisation of the retained testicles. A greater incidence of spontaneous remission of the cryptorchidism was found...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:1989-01-01 00:00:00
abstract::Biliary atresia is a severe neonatal malformation in which the entire extrahepatic biliary tract or part of it is absent and replaced by fibrosclerotic tissue. Having been described for the first time by Thomson in 1891, biliary atresia has an incidence of 1:10,000-15,000 live neonates with a slight predominance in th...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2001-08-01 00:00:00
abstract::Sixty patients (31 male and 29 female) with thalassemia major, aged between 6 and 26 years, 18 of which were splenectomized, were observed in this study evaluating the oro-maxillo-facial alterations and correlating them to transfusion indexes, serum ferritin levels, splenectomy and age. For each patient a haematologic...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract:AIM:The increase in life expectancy of cystic fibrosis (CF) patients has brought about a rise in new clinical problems in these patients, such as a decrease in bone mineral density (BMD). The cause of diminished BMD in CF is multi-factorial. METHODS:The aim of this cross-sectional study, conducted on 39 CF patients un...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2008-04-01 00:00:00