Abstract：
BACKGROUND:Inflammation may represent a common underlying mechanism in a wide range of diseases, including neuropsychiatric disorders. Cytokine involvement has been investigated in some studies on patients with childhood neuropsychiatric diseases. The aim of this study was to determine whether cytokines are involved in ADHD to provide a rationale for immune-based therapeutic strategies in this disorder. METHODS:Sixty children were studied: 34 consecutive drug-naïve children with ADHD (30 males and 4 females; mean age of 10.10 years, sd=2.43 age) and 26 healthy control children (22 males and 4 females; mean age of 10.70 years, sd=1.81). All cytokines but IL-2 (IL4-IL6-IL10- IL17-TNFA and IFNG) were studied by ELISAs; IL-2 was instead studied by means of paired anti-cytokine Abs and cytokine standards obtained from PharMingen. RESULTS:Data reveal higher IL-6 and IL-10 levels in ADHD patients than in the control group (p= .03). No differences emerged between the two groups for the other cytokines. CONCLUSIONS:Our study shows an imbalance between pro- and anti-inflammatory cytokines that may play a pivotal role in the pathogenesis of ADHD.
journal_name
Minerva Pediatrjournal_title
Minerva pediatricaauthors
Donfrancesco R,Nativio P,Borrelli E,Giua E,Andriola E,Villa MP,DI Trani Msubject
Has Abstractpub_date
2016-12-22 00:00:00eissn
0026-4946issn
1827-1715pii
S0026494616046429pub_type
杂志文章abstract：:Bacterial meningitis is an infection of the central nervous system involving quite a number of neurological sequelae the most common of which is hearing impairment. To assess the incidence of audiological deficit the authors evaluated retrospectively 20 patients, between 4 months and 11 years of age, observed at the P...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：1995-10-01 00:00:00
abstract：:The authors describe Poland's anomaly in a boy aged three years and four months, characterised by a depression in the right hemithorax caused by the absence of the medial extremity of the large pectoral muscle with hypoplasia of the remaining venter musculi. Moreover, the scan showed the absence of the small homolater...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：1997-01-01 00:00:00
abstract：BACKGROUND:We explored the clinical efficacy of vitamin A combined with vitamin B in the prevention and treatment of premature infants with anemia. METHODS:One hundred fifty cases of premature infants were divided into three groups. Vitamin A combined with recombinant human erythropoietin (group A), vitamin B combined...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：10.23736/S0026-4946.17.05049-6
更新日期：2019-02-01 00:00:00
abstract：:This paper reports a case of pyloric duplication, an extremely rare abnormality usually discovered during infancy. Clinical findings involved mainly symptoms of obstruction and radiological evaluation included abdominal US, plain radiography and CT imaging. Pyloric duplication was diagnosed by US and confirmed by CT s...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2006-08-01 00:00:00
abstract：BACKGROUND:This study evaluates endoscopic and quality of life (QoL) outcomes in two groups, composed by both allergic (A) and non-allergic (N-A) adolescents undergoing septoplasty with concurrent turbinate surgery by radiofrequency treated after surgery with nasal spray containing liposomes and vitamins A and E. METH...
journal_title：Minerva pediatrica
pub_type： 杂志文章,随机对照试验
doi：10.23736/S0026-4946.16.04600-4
更新日期：2017-02-01 00:00:00
abstract：:Asthma is a condition characterised by airways inflammation and bronchial hyperresponsiveness to specific and aspecific spasmogens associated with reversible airways obstruction. The bronchomotor tone is the result of an interaction between neurotransmitter release and local mediators. The efferent neurohumoral pathwa...
journal_title：Minerva pediatrica
pub_type： 杂志文章,评审
doi：
更新日期：2000-11-01 00:00:00
abstract：:We report a case of esophageal achalasia in a nine months old baby. Recurrent cough and cyanosis were the most important clinical findings. Esophagomyotomy remarkably improved the clinical symptoms. Disorders of esophageal motility may be an important cause of respiratory emergencies in the first year of life. ...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：1991-06-01 00:00:00
abstract：AIM:The aim of this study was to critically compare 9 different questionnaires for the evaluation of the Quality of Life in children affected by asthma. METHODS:The questionnaires were analyzed by considering their psychometric characteristics (reliability, validity, responsiveness, least clinically relevant differenc...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2003-08-01 00:00:00
abstract：:A comprehensive study on the rights of the adolescent to the protection of his health according to existing Italian legislation is carried out. After a full examination of international law, the author carefully evaluates all specific articles of the Italian Constitution and all the civil and penal code articles rega...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：1983-04-30 00:00:00
abstract：:Chronic viral hepatitis B and C infections are highly prevalent and create a substantial burden to healthcare systems globally. These two chronic infections are the cause of significant global morbidity and mortality with approximately 1 million annual deaths attributable to them and their sequelae. Children are vulne...
journal_title：Minerva pediatrica
pub_type： 杂志文章,评审
doi：
更新日期：2014-10-01 00:00:00
abstract：: ...
journal_title：Minerva pediatrica
pub_type： 信件
doi：10.23736/S0026-4946.17.04790-9
更新日期：2019-10-01 00:00:00
abstract：:The embryology of the ear and the different congenital anomalies depending on the arrest in development at a particular embryologic date are reviewed. The historical and the actual attitude towards surgical correction is discussed. The classification system, the evaluation and patients selection, the timing of auricul...
journal_title：Minerva pediatrica
pub_type： 杂志文章,评审
doi：
更新日期：2000-12-01 00:00:00
abstract：AIM:To evaluate the prevalence of ultrasound diagnosis of adenomyosis and endometriosis in young women complaining of pelvic pain and to find the symptoms and clinical characteristics associated with these diseases in young women. METHODS:Cross-sectional study, including 100 young women (14-24 years) with a history of...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：10.23736/S0026-4946.20.05842-9
更新日期：2020-06-16 00:00:00
abstract：BACKGROUND:Specific learning disabilities are disorders that affect the instrumental skills of academic learning, leaving intact the general intellectual functioning. It is possible to distinguish: dyslexia, dysorthography, dysgraphia, and dyscalculia. The diagnosis is made according to DSMV. The aim of this study is t...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：10.23736/S0026-4946.18.05036-3
更新日期：2018-04-12 00:00:00
abstract：AIM:The estimation of peak expiratory flow (PEF) in children is a very easy and practical way to check lung function and helps in the diagnosis, treatment follow-up and evaluation of the development of chronic obstructive pulmonary disease. METHODS:Using a Mini-Wright flowmeter (Clement Clarke International Ltd, Engla...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2005-04-01 00:00:00
abstract：:The study of children with focal brain injury has important implications from a clinical and theoretical perspective. Clinical data on children with congenital or early acquired lesions indicates that the cognitive sequelae are different from those resulting from similar damage sustained in adulthood. These difference...
journal_title：Minerva pediatrica
pub_type： 杂志文章,评审
doi：
更新日期：1993-06-01 00:00:00
abstract：BACKGROUND:The aim of this paper was to examine the present situation of adolescents admission for respiratory emergency, management of these patients, identify strategies for the best therapeutic options and better collaboration. METHODS:We have gathered data of adolescent patients who were referred to the Emergency ...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2002-12-01 00:00:00
abstract：AIM:Myelomeningocele (MMC), among others functions, affects colorectal motility and bowel emptying, and often leads to constipation, faecal incontinence, or a combination of both. We investigated the benefits of transanal irrigation (TI) in children with MMC through the radiological study of intestinal transit time. M...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2013-06-01 00:00:00
abstract：:Between 1998 and 2000, four newborns have been observed for laryngeal stridor occurred some hours after birth. Otorhinolaryngologic examinations, as well as cardiac, neuroradiologic and serologic investigations have been performed to formulate the diagnosis and verify the etiology. The fiberoptic laryngoscopy showed a...
journal_title：Minerva pediatrica
pub_type： 杂志文章,评审
doi：
更新日期：2002-04-01 00:00:00
abstract：:This study describes the blood pressure (BP), heart rate and weight distribution of 1214 school-age children (6-11 years old) in Messina. The systolic BP is significantly correlated with weight in every age and in both sexes. The incidence of BP values equal or above the 95 degrees percentile are significantly higher ...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：1990-04-01 00:00:00
abstract：BACKGROUND:This study aims to evaluate the association of consuming healthy foods with anthropometric measures and blood pressure (BP) in a national sample of Iranian children and adolescents. METHODS:This nationwide study was conducted in 2011-2012 among 13,486 students, aged 6-18 years, selected by multistage cluste...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：10.23736/S0026-4946.16.04337-1
更新日期：2019-10-01 00:00:00
abstract：:Acute disseminated staphylococcal disease (ADSD) constitutes a potentially fatal and alarmingly increasing disorder. We describe an unusual case of a two-and-a-half-year-old female with community-acquired methicillin-resistant Staphylococcus aureus induced septic shock complicated by osteomyelitis and deep vein thromb...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2013-04-01 00:00:00
abstract：:A preliminary undiagnosed case of partial carbamyl-phosphate-synthetase deficiency in a 14 year old patient is described. This extremely rare metabolic disorder is unlikely to produce clinical symptoms at such an advanced age. Details are given of the clinical picture, the diagnosis (by liver biopsy and post mortem li...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：1989-02-01 00:00:00
abstract：AIM:The objective of this paper is an empirical analysis of mother-infant feeding interactions through an observational instrument (Feeding Scale), which is applied to the videotape of a feeding session. METHODS:Three samples of mothers and their children have been examined (104 couples with children ranging in age fr...
journal_title：Minerva pediatrica
pub_type： 杂志文章,评审
doi：
更新日期：2003-06-01 00:00:00
abstract：:Both systolic and diastolic dysfunction in the pediatric population can be identified by bedside echocardiography and can guide therapy and evaluate response to therapy. Isolated diastolic dysfunction is rare in children; however many conditions can lead to systolic dysfunction. In this review various echocardiographi...
journal_title：Minerva pediatrica
pub_type： 杂志文章,评审
doi：
更新日期：2011-10-01 00:00:00
abstract：BACKGROUND:Obesity is a condition that increases the risk of developing several health problems, resulting in high health care costs worldwide. Therefore, it is important to investigate several avenues for the control of this condition. This study aimed to identify a dermatoglyphical condition that distinguishes obesit...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：10.23736/S0026-4946.20.05731-X
更新日期：2021-01-13 00:00:00
abstract：AIM:The increase in life expectancy of cystic fibrosis (CF) patients has brought about a rise in new clinical problems in these patients, such as a decrease in bone mineral density (BMD). The cause of diminished BMD in CF is multi-factorial. METHODS:The aim of this cross-sectional study, conducted on 39 CF patients un...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2008-04-01 00:00:00
abstract：BACKGROUND:Neonatal hypoxic-ischemic encephalopathy is still a significant cause of neonatal death and neurodevelopmental disabilities, such as cerebral palsy, mental delay, and epilepsy. After the introduction of therapeutic hypothermia, the prognosis of hypoxic-ischemic encephalopathy has improved, with reduction of ...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：10.23736/S0026-4946.18.05224-6
更新日期：2018-07-02 00:00:00
abstract：:Heart failure can be defined as the inability of the heart to sufficiently support the circulation. In the fetus, heart failure can be caused by a myriad of factors that include fetal shunting abnormalities, genetic cardiomyopathies, extracardiac malformations, arrhythmias and structural congenital heart disease. With...
journal_title：Minerva pediatrica
pub_type： 杂志文章,评审
doi：
更新日期：2012-10-01 00:00:00
abstract：BACKGROUND:The aim of this study was to analyze multidrug resistance-associated protein 1 (MRP1) expression of peripheral blood of children intractable epilepsy. METHODS:Sixty children with epilepsy admitted to outpatient and inpatient services of Xuzhou Children's Hospital between November 2010 and October 2011 were ...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：10.23736/S0026-4946.16.04358-9
更新日期：2018-04-01 00:00:00
