[Treatment of bronchial asthma in chidren].

Abstract:

:Asthma is a condition characterised by airways inflammation and bronchial hyperresponsiveness to specific and aspecific spasmogens associated with reversible airways obstruction. The bronchomotor tone is the result of an interaction between neurotransmitter release and local mediators. The efferent neurohumoral pathways to the muscular, vascular and glandular element include parasympathetic nerves, sympathetic nerves, and non-adrenergic non-cholinergic (NANC) neurotransmission. It is currently recognised that the alteration of these mechanisms can induce bronchial hyperresponsiveness that represents a characteristic feature of asthma. Asthma is common in children and its prevalence in this age group is increasing. The current therapy of asthma involves the use of anti-inflammatory drugs to control the underlying process (causal therapy) and the use of bronchodilators that provide rapid relief of bronchoconstriction (symptomatic therapy). The bronchodilators are represented by beta 2 adrenergic agonists, methylxanthines and anti-cholinergic drugs; the anti-inflammatory drugs are represented by corticosteroids, antileukotrienes and chromones. Other new therapies being studied include anti-immunoglobulin E, anti IL-5 agents, endothelin receptor antagonists, and others.

journal_name

Minerva Pediatr

journal_title

Minerva pediatrica

authors

Rossi F,Gallelli L,Marrocco G,Capristo C,Miraglia Del Giudice M,Maisto A,Brunese FP,D'Agostino B,Capristo AF

keywords:

subject

Has Abstract

pub_date

2000-11-01 00:00:00

pages

641-57

issue

11

eissn

0026-4946

issn

1827-1715

journal_volume

52

pub_type

杂志文章,评审
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    authors: Dal Molin A,Gatta C,Festini F

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    authors: Aivazis V,Hatzimichail A,Stavridis J,Bourli E,Konstantinidis TH,Katsougiannopoulos V

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    authors: Palagiano A,Pace MC

    更新日期:1993-05-01 00:00:00

  • Multicystic dysplastic kidney and contralateral vesicoureteral reflux. Renal growth.

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    pub_type: 杂志文章

    doi:

    authors: Fanos V,Sinaguglia G,Vino L,Pizzini C,Portuese A

    更新日期:2001-04-01 00:00:00

  • [RAST positivity for food in atopic dermatitis].

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    authors: Ferrari G,De Amici M,Notarangelo LD,Monafo V,Burgio GR

    更新日期:1989-03-01 00:00:00

  • [Visceral leishmaniasis complicated by herpes zoster. An unusual case in the pediatric age].

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    doi:

    authors: Di Martino L,Nocerino A,Pettoello M,Toscano P,Franzese A,Di Maio S

    更新日期:1992-01-01 00:00:00

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    pub_type: 杂志文章

    doi:

    authors: Marazzi MC,Germano P,Liotta G,Buonomo E,Guidotti G,Palombi L

    更新日期:2006-10-01 00:00:00

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    authors: Caiulo VA,Lupetti L,Ughi C,Cortigiani L,Ceccarelli M

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  • [Perineal ectopic testis. Report of seven cases].

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    authors: Campobasso P,Schieven E,Sica F

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    abstract:BACKGROUND:Previous trials, performed in subjects affected by recurrent streptococcal pharyngo-tonsillar infection, have shown that the use for 90 days of Streptococcus salivarius K12 (K12), an oral colonizing probiotic producing lantibiotic bacteriocins, reduces the occurrence of streptococcal and viral pharyngitis an...

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    journal_title:Minerva pediatrica

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    authors: Di Comite A,De Vita L,Pierucci I,Pilone R,Cristiano L,D'Elia R,Gaudio R,Manente G

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    doi:

    authors: Roberi PL,Inglese V

    更新日期:1991-07-01 00:00:00

  • [Evaluation of the fluidifying effect on nasal mucus of physiologic solution combined with increasing concentrations of polysorbates].

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    doi:

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    更新日期:1992-09-01 00:00:00

  • [A case of growth retardation of rare occurrence].

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    doi:

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    doi:

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