What is the current role for parenteral lipid emulsions containing omega-3 fatty acids in infants with short bowel syndrome?

Abstract:

:Parenteral nutrition associated liver disease is the most common complication of pediatric short bowel syndrome (SBS). There is emerging evidence that the disease may be reversed with the use of parenteral lipid emulsions derived from fish-oils, which contain significant concentrations of omega-3 fatty acids (w3FA). This paper will review the rationale for the use of parenteral lipid emulsions containing w3FA in SBS and the evidence for their efficacy. Given the promising results and apparent safety of these emulsions, we shall also consider what the current role for PN lipid emulsions containing w3FA in children with SBS should be.

journal_name

Minerva Pediatr

journal_title

Minerva pediatrica

authors

Diamond IR,Pencharz PB,Wales PW

subject

Has Abstract

pub_date

2009-06-01 00:00:00

pages

263-72

issue

3

eissn

0026-4946

issn

1827-1715

journal_volume

61

pub_type

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