Key-role of thyrotropin deficiency in disclosing craniopharyngioma diagnosis in a short girl with Hashimoto's thyroiditis.

Abstract:

:In a short girl with celiac disease and Hashimoto's thyroiditis (HT), suspicion of an associated pituitary lesion was suggested by the finding of a thyroid function pattern that was not compatible with HT-related hypothyroidism (low FT4 with normal TSH). This case report reinforces the view that the finding of a normal TSH in presence of a low FT4 should always alert pediatricians and raise suspicion of central hypothyroidism, even when a primary thyroid disease has been already identified. In this case TSH deficiency played a critical role in disclosing diagnosis of craniopharyngioma (CP). Therefore, the subsequent work-up was directed towards investigating pituitary function and morphology. Endocrinological investigations evidenced a picture of TSH and other pituitary hormone deficiency, whereas magnetic resonance imaging revealed an intrasellar CP. Therefore, in this case TSH deficiency played a key-role in disclosing CP diagnosis.

journal_name

Minerva Pediatr

journal_title

Minerva pediatrica

authors

Aversa T,Valenzise M,Zirilli G,Lombardo F,De Luca F,Wasniewska M

subject

Has Abstract

pub_date

2016-04-01 00:00:00

pages

152-4

issue

2

eissn

0026-4946

issn

1827-1715

pii

R15Y9999N00A140003

journal_volume

68

pub_type

杂志文章
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    authors: Campobasso P,Schieven E,Sica F

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    doi:

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    更新日期:2015-06-01 00:00:00

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    pub_type: 杂志文章,评审

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    doi:

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    更新日期:2010-06-01 00:00:00

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    authors: Bergonzi F,Mangili G

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    doi:

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    更新日期:1992-09-01 00:00:00

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  • [Rheumatic chorea: a still actual pathology?].

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    更新日期:1996-06-01 00:00:00

  • [Future perspectives in the therapy of asthma in children].

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    pub_type: 杂志文章,评审

    doi:

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    更新日期:2008-04-01 00:00:00

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    pub_type: 杂志文章,评审

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