Abstract:
:Infants born prematurely before 37 weeks of gestational age (GA) have particular anatomical, immunological and metabolic characteristics that predispose them, even in the absence of diseases at birth, to severe morbidity. Respiratory syncytial virus (RSV) is the leading cause of hospitalization for lower respiratory tract infections (LRTI) in the first year of life, as well as an important cause of respiratory outcomes as recurrent wheezing in industrialized countries or mortality in developing countries. Prematurity is an important risk factor for hospitalization for severe RSV disease, but epidemiological, environmental and demographic risk factors also play a role in RSV infection. Currently, there is no effective antiviral therapy for the treatment of RSV infection, nor the possibility of using maternal immunization or vaccination of children to prevent infection, although numerous preclinical and clinical studies are still ongoing. Passive immunization with palivizumab has been shown to be safe and effective in preventing RSV hospitalization in children at greater risk of contracting a serious infection. Costs associated with palivizumab prophylaxis and its monthly intramuscularly administration has prompted many health institutions of different countries to implement specific recommendations, with the aim of protecting at risk infants for whom RSV infection is likely to cause serious illness or death. The cost-effectiveness ratio of prophylaxis, related to reduce hospitalization costs and the impact of the burden of RSV disease worldwide, greatly affects the drafting and the adoption of specific recommendations and the adherence to them, concerning the passive immunization with palivizumab.
journal_name
Minerva Pediatrjournal_title
Minerva pediatricaauthors
Del Vecchio A,Franco C,Del Vecchio K,Umbaldo A,Capasso L,Raimondi Fdoi
10.23736/S0026-4946.18.05300-8subject
Has Abstractpub_date
2018-12-01 00:00:00pages
579-588issue
6eissn
0026-4946issn
1827-1715pii
S0026-4946.18.05300-8journal_volume
70pub_type
杂志文章,评审abstract::Cystic fibrosis (CF) is an inherited, prematurely lethal rare disease affecting more than 85,000 people worldwide. CF is caused by more than 2000 loss-of-function mutations in the gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR). This review summarizes recent advances in the etiological t...
journal_title:Minerva pediatrica
pub_type: 杂志文章,评审
doi:10.23736/S0026-4946.19.05506-3
更新日期:2019-06-01 00:00:00
abstract:BACKGROUND:The aim of this study is to investigate the use of methylene blue in perioperative identification of the patent processus vaginalis in a group of boys presenting with congenital or recurrent hydrocele where surgery was performed by junior surgeons in training. METHODS:We retrospectively reviewed the notes o...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:10.23736/S0026-4946.17.04661-8
更新日期:2020-04-01 00:00:00
abstract::Personal experience of a series of mycoplasma-induced pneumoniae is reported. The importance of early diagnosis for the purpose of speedy target antibiotic therapy is reiterated. Stress is laid on the absence of complications in all patients studied. ...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:1989-06-01 00:00:00
abstract:AIM:To verify the efficacy of botulinus toxin A (TB-A) in treating children with neuropathic bladder secondary to myelomeningocele (MMC) with detrusor hyperactivity/low compliance, resistance to pharmacological therapy, and candidates for enterocystoplasty. METHODS:From January 2002 to June 2003, a group of 7 patients...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2005-02-01 00:00:00
abstract::The Authors describe an uncommon case of growth retardation; the clinical and radiological elements that the Authors to a diagnosis of spondyloepiphyseal dysplasia (SED) are noted; they compare this to other diagnosis of different types of growth retardation, they underline the necessity of taking these rare types int...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:1992-07-01 00:00:00
abstract:AIM:The estimation of peak expiratory flow (PEF) in children is a very easy and practical way to check lung function and helps in the diagnosis, treatment follow-up and evaluation of the development of chronic obstructive pulmonary disease. METHODS:Using a Mini-Wright flowmeter (Clement Clarke International Ltd, Engla...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2005-04-01 00:00:00
abstract::Bacterial meningitis is an infection of the central nervous system involving quite a number of neurological sequelae the most common of which is hearing impairment. To assess the incidence of audiological deficit the authors evaluated retrospectively 20 patients, between 4 months and 11 years of age, observed at the P...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:1995-10-01 00:00:00
abstract:BACKGROUND:Aim of study was to ascertain the possible presence of congenital dysplasia of the hip in infants (CDH) in the population immigrated from countries where the problem is surely neglected from the local health service and estimate its incidence. Moreover to observe the impact of the CDH problem on the parents ...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:1997-10-01 00:00:00
abstract::The onset of puberty may be late - in the latter part of the predicted normal range or truly delayed - beyond this range. The latest age to start is usually regarded as 13 years in girls and 14 years in boys. There may also be a delayed completion of puberty, 16 years in girls and 17 years in boys. The initial approac...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:10.23736/S0026-4946.20.05968-X
更新日期:2020-12-01 00:00:00
abstract::The paper illustrates the characteristics of external fixators (EF) (Wagner, FEA, Ilizarov) regularly used in pediatric surgery. Attention is focused on the indications for their use in orthopedics and traumatology during the developmental age. In conclusion, their use, even though in traumatology this is more restric...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract::Early recognition of shock is the key to successful resuscitation in critically ill children. Often, shock results in or co-exists with myo-cardial dysfunction or acute lung injury. Recognition and appropriate management of these insults is crucial for successful outcomes. Resuscitation should be directed to restorati...
journal_title:Minerva pediatrica
pub_type: 杂志文章,评审
doi:
更新日期:2009-02-01 00:00:00
abstract::Noonan syndrome was first described over 20 years ago by Noonan and Ehmke. They defined a specific group of nine patients with valvular pulmonary stenosis who, in addition, had short stature, mild mental retardation, hypertelorism and unusual facies. The incidence of Noonan syndrome has been estimated to be between 1 ...
journal_title:Minerva pediatrica
pub_type: 杂志文章,评审
doi:
更新日期:1993-09-01 00:00:00
abstract:BACKGROUND:In epileptic patients with motor disability, it's difficult to disentangle the effects of antiepileptic drugs (AEDs) on bone health from those provoked by impaired mobility. The aim of this study was to evaluate the effects of AEDs on bone mineral status by phalangeal quantitative ultrasound (QUS), a no-radi...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:10.23736/S0026-4946.18.05235-0
更新日期:2019-05-23 00:00:00
abstract::Thoracic tumours of childhood arise either in the mediastinum, or from the chest wall and rarely from the lung parenchyma. Mediastinal teratoma occur in the anterior mediastinum and are usually very large at presentation; initial treatment is under discussion, but it appears that surgical excision and histological exa...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2012-06-01 00:00:00
abstract:BACKGROUND:This study aims to evaluate the association of consuming healthy foods with anthropometric measures and blood pressure (BP) in a national sample of Iranian children and adolescents. METHODS:This nationwide study was conducted in 2011-2012 among 13,486 students, aged 6-18 years, selected by multistage cluste...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:10.23736/S0026-4946.16.04337-1
更新日期:2019-10-01 00:00:00
abstract:BACKGROUND:Kuwait is one of the Arab countries with the highest prevalence of overweight or obesity. However, few studies have described the prevalence of obesity in this country. The aim of this study is to describe the prevalence of overweight and obesity among Kuwaiti adolescents; and to examine the association of o...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:10.23736/S0026-4946.18.04911-3
更新日期:2019-08-01 00:00:00
abstract:: ...
journal_title:Minerva pediatrica
pub_type: 社论
doi:10.23736/S0026-4946.18.05437-3
更新日期:2018-12-01 00:00:00
abstract:AIM:Considering how eating habits affect the health of children and taking into account the influence of advertising messages, we wanted to investigate the quantity and the typology of advertising on air during children's television programmes. METHODS:The research was conducted beginning in January 2008 up to March 2...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2012-02-01 00:00:00
abstract::Sixty patients (31 male and 29 female) with thalassemia major, aged between 6 and 26 years, 18 of which were splenectomized, were observed in this study evaluating the oro-maxillo-facial alterations and correlating them to transfusion indexes, serum ferritin levels, splenectomy and age. For each patient a haematologic...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract::The association of congenital anal stenosis, or other anal and rectal malformation, sacral defect and a presacral mass is known as the Currarino syndrome described for the first time in 1981. Currarino et al. proposed that abnormal endoectodermal adhesions and notochordal defects in early fetal life may result in a fi...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2005-06-01 00:00:00
abstract::Low grade gliomas (LGG) are the most common brain tumors of childhood and adolescence, consisting of a mixed group of grade I and grade II neoplasms. In general, their location and resectability are the most important predictors of outcome. Surgery is curative, usually for superficial tumors of the cerebral or cerebel...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2013-04-01 00:00:00
abstract::In 113 children with atopic dermatitis RAST results for 9 food mixtures were analyzed. Sixty-eight children (60%) were RAST positive (greater than or equal to ++) for one or more mixture and 87% of those RAST positive had specific IgE for egg and/or cereals and/or legumes. Sensitization to egg, cow milk and meat was m...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:1989-03-01 00:00:00
abstract:INTRODUCTION:Online grooming is an active communicative entrapment network involving a wide range of techniques. The interactions that groomers have with minors online are complex. The purpose of the present literature review is to contribute to the existing knowledge base regarding online sex offender typologies, pred...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:10.23736/S0026-4946.20.05621-2
更新日期:2020-05-15 00:00:00
abstract::Eosinophilic esophagitis (EoE) is a chronic disease characterized by symptoms related to esophageal dysfunction and eosinophil-predominant inflammation (≥15 eosinophils/high power field). In the last ten years, several epidemiological studies showed a significant increase in the incidence and prevalence of EoE, especi...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:10.23736/S0026-4946.20.05913-7
更新日期:2020-10-01 00:00:00
abstract::Chronic kidney disease (CKD) is a continuum of progressive reduction in kidney function lasting for more than three months, due to either structural and/or functional renal abnormalities that may lead to irreversible kidney damage. The term "renal supportive therapy" (RST) generally characterizes the spectrum of dialy...
journal_title:Minerva pediatrica
pub_type: 杂志文章,评审
doi:
更新日期:2012-04-01 00:00:00
abstract:BACKGROUND:To investigate if high dose inhaled beclomethasone dipropionate started early after upper respiratory tract infection (URTI) could reduce recurrent wheezing in infants. METHODS:Twenty-six ambulatory infants, 7-12 months of age, with recurrent wheezing during upper respiratory tract infection participated. A...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2002-06-01 00:00:00
abstract:: ...
journal_title:Minerva pediatrica
pub_type: 信件
doi:10.23736/S0026-4946.19.05297-6
更新日期:2019-10-01 00:00:00
abstract::The remarkable effectiveness of surfactant in neonatology suggested its use also in adults as well as in children on the basis of the pulmonary pathophysiology. We describe a case of an 18 month-old child affected by acute respiratory distress syndrome (ARDS) due to asphyxy by gastric juice inhalation, successfully tr...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2007-12-01 00:00:00
abstract:AIM:The median urinary iodine concentration (UIC) for schoolchildren was 90 microg/L in Biella and 136 microg/L in Novara in survey carried out in 1995-1996. Biella resulted as iodine deficiency area and Novara as iodine sufficient area. Aim of our study was to assess goiter prevalence by ultrasonography in Biella and ...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2006-06-01 00:00:00
abstract::Recently, the prevalence of post-traumatic stress disorder (PTSD) in adolescence is higher than the prevalence of PTSD in adult populations. PTSD and suicidality are often found in populations of adolescents presenting with other emotional disorders (particularly mood disorders), traumatic grief, childhood abuse, and/...
journal_title:Minerva pediatrica
pub_type: 杂志文章,评审
doi:
更新日期:2010-08-01 00:00:00