Abstract:
:Patients with chronic kidney disease (CKD) show a broad spectrum of clinical symptoms intimately related to the disturbed mineral and bone metabolism and summarized as CKD-mineral-bone disorder (CKD-MBD). Whereas in adults an impaired bone metabolism translates mainly into an increased risk of fractures, in pediatric CKD patients rickets, skeletal deformations, and severe growth failure are additional and severe clinical findings. Further-more, an elevated Ca x P ion product, secondary hyperparathyroidism (sHPT) as well as concomitant calcitriol medication have been linked to ectopic (vascular) calcification, in which is strongly associated with the dramatically high cardiovascular morbidity and mortality even in pediatric CKD patients. Thus, in these patients the impaired mineral metabolism is the link between skeletal and cardiovascular disease. In other words, the complex interplay between kidney, skeleton, parathyroid gland, the intestine and the cardiovasculature is severely disturbed in CKD. This review summarizes the recent findings in our understanding of bone cell biology and alterations of mineral metabolism in children with CKD.
journal_name
Minerva Pediatrjournal_title
Minerva pediatricaauthors
Haffner D,Fischer DCsubject
Has Abstractpub_date
2010-06-01 00:00:00pages
273-84issue
3eissn
0026-4946issn
1827-1715pii
R15103555journal_volume
62pub_type
杂志文章,评审abstract::More than one million neonatal deaths every year in the world are attributable to infection. In nurseries, infections occur with a reported incidence of 0.3-3%; in Neonatal Intensive Care Units (NICUs) the reported incidence is 7-24.5%, and up to 40% in newborns with birth weight less than 1000 g or gestational age at...
journal_title:Minerva pediatrica
pub_type: 杂志文章,评审
doi:
更新日期:2013-02-01 00:00:00
abstract:BACKGROUND:In this paper we present growth height standards obtained by an auxological study on a primary school population of central Italy (Lazio), in the 1991-1992 and 1992-1993 school-years. METHODS:4,175 children were included in the study: 2,024 females and 2,151 males, aged from 6 to 11 years. The sampling rate...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:1997-04-01 00:00:00
abstract::Dermatophytosis in newborns and infants has been regarded as very unusual; a case recently observed of a 2-month-old child affected by tinea faciei is described. Twenty days before, localized erythematous infiltrated patches at the upper left eyelid and eyebrows with papules and pustules, were observed. Rarefaction of...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2001-02-01 00:00:00
abstract:BACKGROUND:The aim of this paper was to examine the present situation of adolescents admission for respiratory emergency, management of these patients, identify strategies for the best therapeutic options and better collaboration. METHODS:We have gathered data of adolescent patients who were referred to the Emergency ...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2002-12-01 00:00:00
abstract:AIM:To evaluate the prevalence of ultrasound diagnosis of adenomyosis and endometriosis in young women complaining of pelvic pain and to find the symptoms and clinical characteristics associated with these diseases in young women. METHODS:Cross-sectional study, including 100 young women (14-24 years) with a history of...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:10.23736/S0026-4946.20.05842-9
更新日期:2020-06-16 00:00:00
abstract:BACKGROUND:The aim of this study is to investigate the use of methylene blue in perioperative identification of the patent processus vaginalis in a group of boys presenting with congenital or recurrent hydrocele where surgery was performed by junior surgeons in training. METHODS:We retrospectively reviewed the notes o...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:10.23736/S0026-4946.17.04661-8
更新日期:2020-04-01 00:00:00
abstract::Sixty patients (31 male and 29 female) with thalassemia major, aged between 6 and 26 years, 18 of which were splenectomized, were observed in this study evaluating the oro-maxillo-facial alterations and correlating them to transfusion indexes, serum ferritin levels, splenectomy and age. For each patient a haematologic...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract::Neonatal analgesia is a recent issue: newborns were supposed to feel no pain until the late "80s; but from that date, many studies were performed to verify the extent of neonates" pain perception, ways to measure and overcome it. Pain can have harmful consequences in babies, due to several causes, and we investigated ...
journal_title:Minerva pediatrica
pub_type: 杂志文章,评审
doi:
更新日期:2010-06-01 00:00:00
abstract::To establish the effectiveness of flunisolide + salbutamol vs salbutamol alone administered by metered aerosol in the phlogistic obstructive diseases, 18 children were evaluated. The treatments were evaluated on the basis of ventilatory function parameters and of tolerance. The results proved positive for all drugs, t...
journal_title:Minerva pediatrica
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1990-06-01 00:00:00
abstract::In a short girl with celiac disease and Hashimoto's thyroiditis (HT), suspicion of an associated pituitary lesion was suggested by the finding of a thyroid function pattern that was not compatible with HT-related hypothyroidism (low FT4 with normal TSH). This case report reinforces the view that the finding of a norma...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2016-04-01 00:00:00
abstract::Biliary atresia is a severe neonatal malformation in which the entire extrahepatic biliary tract or part of it is absent and replaced by fibrosclerotic tissue. Having been described for the first time by Thomson in 1891, biliary atresia has an incidence of 1:10,000-15,000 live neonates with a slight predominance in th...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2001-08-01 00:00:00
abstract::The diagnosis of fetal tachyarrhythmia during a routine ultrasound scan imposes a continuous monitoring of fetal heart function through ECG and M-mode echocardiography. Since fetal dysrhythmia can lead to non-immune hydrops or to fetal death a correct diagnosis and an adequate intrauterine therapy are fundamentally im...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:1993-05-01 00:00:00
abstract::One of the principal duties of a staff nurse working in a NICU is the assistance of the ventilated infants. The management of the endotracheal tube is a key moment in the neonatal care and it is fundamental to prevent the ventilator induced lung injury and the change in the perfusion (especially in the brain) that may...
journal_title:Minerva pediatrica
pub_type: 杂志文章,评审
doi:
更新日期:2010-06-01 00:00:00
abstract:AIM:Myelomeningocele (MMC), among others functions, affects colorectal motility and bowel emptying, and often leads to constipation, faecal incontinence, or a combination of both. We investigated the benefits of transanal irrigation (TI) in children with MMC through the radiological study of intestinal transit time. M...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2013-06-01 00:00:00
abstract::Anti-endomysium antibodies (AEA) and Antigliadin antibodies (AGA) have been compared in a group of coeliac patients (17 with untreated coeliac disease, 56 after gluten free diet and 14 after gluten challenge), in 69 patients with various intestinal pathological conditions, and in 40 healthy children, in order to appre...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract:BACKGROUND:YouTube is overloaded with various medical videos and has become a common source for surgeons and the general public alike to update on surgical procedures. This study determined the quality and benefits of information with regards to laparoscopic pyloromyotomy on YouTube. METHODS:A search was performed on ...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:10.23736/S0026-4946.18.05178-2
更新日期:2018-07-18 00:00:00
abstract:BACKGROUND:Developmental Dyslexia is a disorder, highly frequent in the school population, for which the recommended rehabilitation procedures are not well defined. This study aimed to automatize reading decoding skills by using an innovative system for rehabilitation, based on a telerehabilitation method. It requires ...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:10.23736/S0026-4946.16.04426-1
更新日期:2018-12-01 00:00:00
abstract::In 1967 a baby was observed who presented post-natal progressive growth deficit, mental retardation, craniofacial dysmorphias and other malformations which didn't form part of the syndromes till then known. However the first description of patients with this combination of anomalies dates back to 1981, when Niikawa an...
journal_title:Minerva pediatrica
pub_type: 杂志文章,评审
doi:
更新日期:1999-07-01 00:00:00
abstract::The Femoral hypoplasia - unusual facies syndrome (FHUF) or Femoral - facial syndrome (FFS) was at first described in 1975. Up to now about 60 cases have been reported. According to our knowledge only 4 cases have had congenital central nervous system's malformations, furthermore the main stages of psychomotor developm...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2011-08-01 00:00:00
abstract::The introduction of the new diagnostic tools for neuroimaging has resulted in the early recognition of congenital brain tumors. In the present report we describe 39 children, in whom the diagnosis of an intracranial tumor has been obtained during the first 12 months of life. These patients represent 14.4% of a pediatr...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:1990-11-01 00:00:00
abstract:BACKGROUND:Plasma-exchange (PEX) has been well described in pediatrics, but most of the current indications are derived from adult experience. Aim of the study was to review the PEX treatments in our Unit over a six-year period. METHODS:Three hundred and seventy-seven PEX sessions were performed in 38 patients (median...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:10.23736/S0026-4946.16.04152-9
更新日期:2017-04-01 00:00:00
abstract::This study describes the blood pressure (BP), heart rate and weight distribution of 1214 school-age children (6-11 years old) in Messina. The systolic BP is significantly correlated with weight in every age and in both sexes. The incidence of BP values equal or above the 95 degrees percentile are significantly higher ...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:1990-04-01 00:00:00
abstract:BACKGROUND:The aim of our study was multifaceted neurodevelopmental examination of children born prematurely with very low birth weight (VLBW) in order to evaluate the usefulness of popularly used tests. The second aim of the study was exploration of risk and protective factors of neurodevelopmental impairment. METHOD...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:10.23736/S0026-4946.16.04513-8
更新日期:2019-08-01 00:00:00
abstract:AIM:Recently, it was reported that the development of breast tissue and secondary sex characteristics in girls occurred at much younger age and the incidences of premature thelarce (PT) and central idiopathic precocious puberty (ICPP) are increasing. In this context, we wanted to evaluate the mycoestrogen exposure as t...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2014-12-01 00:00:00
abstract:BACKGROUND:Obesity is a condition that increases the risk of developing several health problems, resulting in high health care costs worldwide. Therefore, it is important to investigate several avenues for the control of this condition. This study aimed to identify a dermatoglyphical condition that distinguishes obesit...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:10.23736/S0026-4946.20.05731-X
更新日期:2021-01-13 00:00:00
abstract:BACKGROUND:Intrauterine growth restriction (IUGR) is caused by fetal growth below what is normal for its genetic potential. Recent studies have shown a distinct association between changes in umbilical artery flow in IUGR subjects and an increased risk of respiratory morbidity and was to find the impact of IUGR on the ...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:10.23736/S0026-4946.17.04965-9
更新日期:2017-05-31 00:00:00
abstract::This article provides current guidelines on the treatment and prevention of childhood obesity. Since factors involved in obesity change with age, the therapeutic approach in pre-school children will be different from pupils and adolescents. The treatment will also be modulated on the basis of weight excess, weight gai...
journal_title:Minerva pediatrica
pub_type: 指南,杂志文章,实务指引
doi:
更新日期:2003-10-01 00:00:00
abstract::Congenital dermal sinus represents a dysraphic state of the central nervous system. It can show up throughout a defect of the midline, of both the skull and the spine. Usually, the malformation presents a fistulous tract, connecting the skin with the underlying tissues (hypoderm, paraspinal muscles, vertebrae and, in ...
journal_title:Minerva pediatrica
pub_type: 杂志文章,评审
doi:
更新日期:1990-12-01 00:00:00
abstract::Severe atopic dermatitis causes major impairment in the life of both children and their parents. Generally, symptoms can be controlled with emollients, topical steroids, antibiotics, antihistaminic but some patients remain intensely ill and may require treatment with systemic steroids and so on. Cyclosporin has been f...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2004-04-01 00:00:00
abstract:AIM:The aim of this study was to evaluate the reaction to the procedural pain of preterm newborn and to demonstrate the different effectiveness of the two analgesic and not pharmacological techniques of recent clinical acquisition, the use of glucose solution and the sensorial saturation, in order to identify an optima...
journal_title:Minerva pediatrica
pub_type: 杂志文章,随机对照试验
doi:
更新日期:2011-08-01 00:00:00