Abstract:
BACKGROUND:There has been a paucity of data about the therapeutic efficacy of bronchoalveolar lavage (BAL) for pediatric refractory Mycoplasma pneumonia pneumonia (RMPP) complicated with atelectasis. This study aims to evaluate the clinical effectiveness and safety of BAL in pediatric RMPP inpatients complicated with atelectasis. METHODS:Totally 225 children diagnosed as having RMPP with radiological proven irreversible atelectasis completed this study. According to whether they received BAL treatment, they were divided into BAL-intervention group (n=125) and the control group (n=100). Clinical, laboratory and radiological effects were compared between these two groups. Bronchoscopic imaging features were also comprehensively investigated. RESULTS:Compared with control group, the febrile days after enrollment was significantly shorter in BAL-intervention group (3.0±1.6 d) compared with that in control group (4.1±1.7 d) (P<0.01). The duration of coughing was 3.1±1.7 d in BAL-intervention group and 4.6±1.8 days in the control group (P<0.01). The duration of abnormal lung auscultation was 3.8±1.8 d in intervention group and 5.8±1.6 d in the control group (P<0.01). The length of hospital stays was 5.8±1.6 days and 7.8±1.9 days (P<0.01), respectively. We also found that WBC count (P<0.01) and CRP value (P<0.01) recovered more quickly in BAL-intervention group compared with that in the control group. Seven days after admission, 85.6% of patients in BAL-intervention group showed atelectasis resolution versus 39.0% in control group (P<0.01), and for pleural effusion disappearance 78.4% versus 43.0% (P<0.01). CONCLUSIONS:Our data suggested that BAL intervention combined with regular drug usage and prednisolone is a better treatment for RMPP children complicated with atelectasis than conventional drug therapy alone.
journal_name
Minerva Pediatrjournal_title
Minerva pediatricaauthors
Li F,Zhu B,Xie G,Wang Y,Geng Jdoi
10.23736/S0026-4946.20.05538-3subject
Has Abstractpub_date
2020-04-02 00:00:00eissn
0026-4946issn
1827-1715pii
S0026-4946.20.05538-3pub_type
杂志文章abstract::Aspecific chronic diarrhea is one of the most common causes of protracted diarrhea in infancy. The pathology is characterised by an increased frequency of daily bowel movement with half-formed feces; it is not associated to malabsorption syndrome or enteric infections and appears to be correlated to an unbalanced diet...
journal_title:Minerva pediatrica
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1990-04-01 00:00:00
abstract:BACKGROUND:The aim of this study was to analyze multidrug resistance-associated protein 1 (MRP1) expression of peripheral blood of children intractable epilepsy. METHODS:Sixty children with epilepsy admitted to outpatient and inpatient services of Xuzhou Children's Hospital between November 2010 and October 2011 were ...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:10.23736/S0026-4946.16.04358-9
更新日期:2018-04-01 00:00:00
abstract:BACKGROUND:Glioma is the most common extracranial solid tumor of children. The malignant (cancer) cells form in neural crest cell of the adrenal gland. In this study we investigate the expressions of Myogenin and OCT4 in Glioma which might be used as prognostic makers for this deteriorated disease. METHODS:We used Qua...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:10.23736/S0026-4946.18.05396-3
更新日期:2018-12-03 00:00:00
abstract:AIM:The median urinary iodine concentration (UIC) for schoolchildren was 90 microg/L in Biella and 136 microg/L in Novara in survey carried out in 1995-1996. Biella resulted as iodine deficiency area and Novara as iodine sufficient area. Aim of our study was to assess goiter prevalence by ultrasonography in Biella and ...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2006-06-01 00:00:00
abstract::Infants born prematurely before 37 weeks of gestational age (GA) have particular anatomical, immunological and metabolic characteristics that predispose them, even in the absence of diseases at birth, to severe morbidity. Respiratory syncytial virus (RSV) is the leading cause of hospitalization for lower respiratory t...
journal_title:Minerva pediatrica
pub_type: 杂志文章,评审
doi:10.23736/S0026-4946.18.05300-8
更新日期:2018-12-01 00:00:00
abstract:BACKGROUND AND AIMS:The hypothesis of an emotional component in asthma has been put forward since antiquity. It is currently explored using a psychodynamic, cognitive-behavioural and systemic-relational approach. This study, carried out using a psychodynamic approach, aimed to identify the psychological aspects of recu...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:1998-03-01 00:00:00
abstract::We studied 13 children and adolescents during diabetic ketoacidosis; the duration of diabetes ranged from 1.4 to 6.0 years. A group of 13 diabetic sex, age and duration of disease-matched children served as control. Patients in ketoacidosis showed important abnormalities of T subset percentages (OKT3: 63.4 +/- 1.87% v...
journal_title:Minerva pediatrica
pub_type: 临床试验,杂志文章
doi:
更新日期:1992-05-01 00:00:00
abstract:BACKGROUND:This study aims to evaluate the association of consuming healthy foods with anthropometric measures and blood pressure (BP) in a national sample of Iranian children and adolescents. METHODS:This nationwide study was conducted in 2011-2012 among 13,486 students, aged 6-18 years, selected by multistage cluste...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:10.23736/S0026-4946.16.04337-1
更新日期:2019-10-01 00:00:00
abstract::In the present study the authors investigated the normal range of the marker TPA in the sera of 100 children (apparently healthy) aged from 0 to 6 years. Well-defined criteria as guide-lines to the interpretation of laboratory results are a very urgent necessity for the expanding utilization of clinical laboratory dat...
journal_title:Minerva pediatrica
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1994-11-01 00:00:00
abstract::The sudden infant death syndrome (SIDS) is the sudden dead of every infant or small child (usually within the first year of life). It is an unexpected event, according to the anamnesis of the subject, and the necroscopic examination of the event does not allow to demonstrate with success the proper cause of death. The...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2010-04-01 00:00:00
abstract:BACKGROUND:Persistent chylothorax in children is rare. Conservative management represents the gold standard but, in case of failure (persistent effusion or relapse), surgery must be considered. This paper aimed at presenting our series of patients who underwent surgical treatment of persistent idiopathic chylothorax an...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:10.23736/S0026-4946.16.04324-3
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND:COVID-19 has quickly become a worldwide threat to health, travel, and commerce. Studies adressing the clinical-functional presentation of viral infection and physiotherapy management in children are scarce. The purpose statement was to provide current perspectives on the physiotherapy interventions for manag...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:10.23736/S0026-4946.20.06100-9
更新日期:2020-10-27 00:00:00
abstract:BACKGROUND:The aim of this paper was to evaluate demographic and prognostic features of febrile seizures (FSs) in a tertiary center in Turkey. METHODS:A retrospective study of 632 children with FS was conducted from January 1995 to January 2002 in the pediatric neurology and general pediatrics departments of Istanbul ...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:10.23736/S0026-4946.16.04081-0
更新日期:2017-06-01 00:00:00
abstract:BACKGROUND:Recent developments regarding the conservative management of multicystic dysplastic kidney disease (MDKD) have shown a reduction in the well-established practice of elective surgical treatment. It has been seen that in the majority of cases the evolution of MDKD is either partial or complete atrophy. The inc...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:1997-05-01 00:00:00
abstract:AIM:The prevalence of systemic reactions (SR) to Hymenoptera stings in children was estimated in values lower than 1% in early studies but much higher in recent surveys. We evaluated the current prevalence and the incidence of SR and large local reactions (LLR) to Hymenoptera stings in children in Italy. METHODS:The d...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2014-08-01 00:00:00
abstract::The authors report the case of a 13-year-old girl affected with urethritis, conjunctivitis, and oligoarticular arthritis. These symptoms represent the classical triad of Fiessinger-Leroy-Reiter's syndrome. The research for HIV was negative and the antigen HLA B27 was absent. The young patients has been treated by FANS...
journal_title:Minerva pediatrica
pub_type: 杂志文章,评审
doi:
更新日期:1993-07-01 00:00:00
abstract::Antibiotics are a cornerstone to treat bacterial infections and children received more frequently these drugs than any other class of medication. However, the improper and excessive use of antibiotics in the past decades has increased the emergence of resistant bacterial strains. Moreover, the lack of specific pediatr...
journal_title:Minerva pediatrica
pub_type: 杂志文章,评审
doi:
更新日期:2014-02-01 00:00:00
abstract::We report on a young patient who suffered from diabetes mellitus and neurosensorial deafness from the age of two. One year later she was noted to have deteriorated vision and the diagnosis of optic atrophy was made, her visual acuity decreased progressively. At the age of six she was admitted to our hospital because o...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:1995-04-01 00:00:00
abstract:AIM:To test the impact of a public health model to implement HIV pediatric care in Limited Resource Settings. METHODS:A retrospective study on the clinical files of 679 Mozambican children (mean age 4.4 years; SD 3.2), has been carried out. The pediatric patients received HAART (Highly Active Anti-Retroviral Therapy) ...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2006-10-01 00:00:00
abstract::Age of diagnosis and clinical pattern were studied in 97 celiac patients, diagnosed with jejunal biopsy, between 1976-1991. They were selected on the basis of clinical and laboratory patterns. The laboratory tests utilized were steatorrhea and xylose in the first years, while in recent years AGA, ARA and AEA were also...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:1996-09-01 00:00:00
abstract::Parenteral nutrition associated liver disease is the most common complication of pediatric short bowel syndrome (SBS). There is emerging evidence that the disease may be reversed with the use of parenteral lipid emulsions derived from fish-oils, which contain significant concentrations of omega-3 fatty acids (w3FA). T...
journal_title:Minerva pediatrica
pub_type: 杂志文章,评审
doi:
更新日期:2009-06-01 00:00:00
abstract::Gilbert's syndrome is a genetically controlled non-hemolytic unconjugated hyperbilirubinemia, caused by reduced activity of UDP-glucoroniltransferase 1, an enzyme critical in bilirubin metabolism. Several molecular configurations may be implicated in a Gilbert's phenotype. Familial mediterranean fever (FMF) is an inhe...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2008-08-01 00:00:00
abstract::Non-alcoholic fatty liver disease (NAFLD) encompasses a range of liver histology severity and outcomes in the absence of chronic alcohol use. The mildest form is simple steatosis in which triglycerides accumulate within hepatocytes. A more advanced form of NAFLD, non-alcoholic steatohepatitis (NASH), includes inflamma...
journal_title:Minerva pediatrica
pub_type: 杂志文章,评审
doi:
更新日期:2010-12-01 00:00:00
abstract::Heart failure can be defined as the inability of the heart to sufficiently support the circulation. In the fetus, heart failure can be caused by a myriad of factors that include fetal shunting abnormalities, genetic cardiomyopathies, extracardiac malformations, arrhythmias and structural congenital heart disease. With...
journal_title:Minerva pediatrica
pub_type: 杂志文章,评审
doi:
更新日期:2012-10-01 00:00:00
abstract::Early recognition of shock is the key to successful resuscitation in critically ill children. Often, shock results in or co-exists with myo-cardial dysfunction or acute lung injury. Recognition and appropriate management of these insults is crucial for successful outcomes. Resuscitation should be directed to restorati...
journal_title:Minerva pediatrica
pub_type: 杂志文章,评审
doi:
更新日期:2009-02-01 00:00:00
abstract:AIM:The present clinical study was carried out in order to evaluate in a perspective way the incidence of the infections caused by CVC, the micro-organisms mostly involved in the infectious process, the condition of aplasia in patients when blood cultures show positiveness and the incidence of removals expressed as num...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2012-08-01 00:00:00
abstract::Acute disseminated staphylococcal disease (ADSD) constitutes a potentially fatal and alarmingly increasing disorder. We describe an unusual case of a two-and-a-half-year-old female with community-acquired methicillin-resistant Staphylococcus aureus induced septic shock complicated by osteomyelitis and deep vein thromb...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2013-04-01 00:00:00
abstract::Low grade gliomas (LGG) are the most common brain tumors of childhood and adolescence, consisting of a mixed group of grade I and grade II neoplasms. In general, their location and resectability are the most important predictors of outcome. Surgery is curative, usually for superficial tumors of the cerebral or cerebel...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2013-04-01 00:00:00
abstract::The usefulness of measuring xylosaemia, carotenaemia and the antigliadin antibodies in the diagnosis and monitoring of coeliac diseases has been examined, 89 children, 57 with aspecific chronic diarrhoea and 32 with coeliachia were examined. The xylose proved less sensitive (80%) and less specific (84.2%) than caroten...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:1989-09-01 00:00:00
abstract::Congenital dermal sinus represents a dysraphic state of the central nervous system. It can show up throughout a defect of the midline, of both the skull and the spine. Usually, the malformation presents a fistulous tract, connecting the skin with the underlying tissues (hypoderm, paraspinal muscles, vertebrae and, in ...
journal_title:Minerva pediatrica
pub_type: 杂志文章,评审
doi:
更新日期:1990-12-01 00:00:00