Abstract:
BACKGROUND:Glioma is the most common extracranial solid tumor of children. The malignant (cancer) cells form in neural crest cell of the adrenal gland. In this study we investigate the expressions of Myogenin and OCT4 in Glioma which might be used as prognostic makers for this deteriorated disease. METHODS:We used Quantitative Fluorescence PCR (QF-PCR), Enzyme-linked immunosorbent assay (ELISA), and Western-blotting to measure the expression level of Myogenin and OCT4 in surgical removed Glioma from 41 patients in our hospital. RESULTS:Compared to the healthy children the expression of Myogenin and OCT4 was significantly increased in both mRNA and protein level in Glioma tumor cells. In addition, these expressions increased as glioma deterioration. CONCLUSIONS:These findings suggesting the expression of Myogenin and Oct4 may be useful indicators for predicting the prognosis of children with glioma.
journal_name
Minerva Pediatrjournal_title
Minerva pediatricaauthors
Zheng N,Zhang D,Liu Xdoi
10.23736/S0026-4946.18.05396-3subject
Has Abstractpub_date
2018-12-03 00:00:00eissn
0026-4946issn
1827-1715pii
S0026-4946.18.05396-3pub_type
杂志文章abstract::In a short girl with celiac disease and Hashimoto's thyroiditis (HT), suspicion of an associated pituitary lesion was suggested by the finding of a thyroid function pattern that was not compatible with HT-related hypothyroidism (low FT4 with normal TSH). This case report reinforces the view that the finding of a norma...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2016-04-01 00:00:00
abstract:BACKGROUND:Neonatal morbidity and mortality differ between very preterm infants that result from single and those that result from a multiple order pregnancy. The aim of our study was to assess and compare the neonatal morbidity and mortality of multiple versus single very preterm infants. METHODS:Obstetrical and neon...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:10.23736/S0026-4946.19.05592-0
更新日期:2019-11-05 00:00:00
abstract::Bacterial meningitis is an infection of the central nervous system involving quite a number of neurological sequelae the most common of which is hearing impairment. To assess the incidence of audiological deficit the authors evaluated retrospectively 20 patients, between 4 months and 11 years of age, observed at the P...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:1995-10-01 00:00:00
abstract::Avascular necrosis (AN) of bone is a complication of systemic lupus erythematosus (SLE). In the present paper we describe two patients with SLE who presented an AN of femoral condyles 18 months and 2 years respectively after the diagnosis of the disease. In the second case, together with the destructive change of the ...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:1989-01-01 00:00:00
abstract:BACKGROUND:In this paper we present growth height standards obtained by an auxological study on a primary school population of central Italy (Lazio), in the 1991-1992 and 1992-1993 school-years. METHODS:4,175 children were included in the study: 2,024 females and 2,151 males, aged from 6 to 11 years. The sampling rate...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:1997-04-01 00:00:00
abstract::The authors describe Poland's anomaly in a boy aged three years and four months, characterised by a depression in the right hemithorax caused by the absence of the medial extremity of the large pectoral muscle with hypoplasia of the remaining venter musculi. Moreover, the scan showed the absence of the small homolater...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:1997-01-01 00:00:00
abstract::Varicella or chickenpox is a common and highly contagious exanthematic disease caused by the varicella-zoster virus (VZV) that during primary infection has the ability to establish latency. VZV reactivation, even decades after primary infection, causes herpes zoster. In healthy immunocompetent subjects, children in pa...
journal_title:Minerva pediatrica
pub_type: 杂志文章,评审
doi:
更新日期:2016-06-01 00:00:00
abstract::Acute disseminated staphylococcal disease (ADSD) constitutes a potentially fatal and alarmingly increasing disorder. We describe an unusual case of a two-and-a-half-year-old female with community-acquired methicillin-resistant Staphylococcus aureus induced septic shock complicated by osteomyelitis and deep vein thromb...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2013-04-01 00:00:00
abstract::Recently, the prevalence of post-traumatic stress disorder (PTSD) in adolescence is higher than the prevalence of PTSD in adult populations. PTSD and suicidality are often found in populations of adolescents presenting with other emotional disorders (particularly mood disorders), traumatic grief, childhood abuse, and/...
journal_title:Minerva pediatrica
pub_type: 杂志文章,评审
doi:
更新日期:2010-08-01 00:00:00
abstract:BACKGROUND:The aim of this paper was to examine the present situation of adolescents admission for respiratory emergency, management of these patients, identify strategies for the best therapeutic options and better collaboration. METHODS:We have gathered data of adolescent patients who were referred to the Emergency ...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2002-12-01 00:00:00
abstract::Syringocele is a cystic dilation of the excretory bulbourethral Cowper gland duct, and is a rather uncommon finding in pediatric age. It is frequently asymptomatic but sometimes may cause voiding symptoms and urinary tract infection (UTI). This case report describes an unusual manifestation of syringocele presenting w...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2009-02-01 00:00:00
abstract::Contiguous gene deletion syndromes: the importance of an accurate genetic definition for a careful clinical monitoring. Contiguous gene deletion syndromes are so named because the deletion manifests as a distinctive cluster of otherwise unrelated single-gene disorders in the same subject. An accurate genetic definitio...
journal_title:Minerva pediatrica
pub_type: 杂志文章,评审
doi:
更新日期:2010-06-01 00:00:00
abstract::Eosinophilic esophagitis (EoE) is a chronic disease characterized by symptoms related to esophageal dysfunction and eosinophil-predominant inflammation (≥15 eosinophils/high power field). In the last ten years, several epidemiological studies showed a significant increase in the incidence and prevalence of EoE, especi...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:10.23736/S0026-4946.20.05913-7
更新日期:2020-10-01 00:00:00
abstract::Gilbert's syndrome is a genetically controlled non-hemolytic unconjugated hyperbilirubinemia, caused by reduced activity of UDP-glucoroniltransferase 1, an enzyme critical in bilirubin metabolism. Several molecular configurations may be implicated in a Gilbert's phenotype. Familial mediterranean fever (FMF) is an inhe...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2008-08-01 00:00:00
abstract::QT prolongation is rarely seen after acute stress reactions such as burn injury and severe head trauma. Although pathophysiologic mechanism is not entirely clear, acute stress is thought to contribute to the inhomogeneity of ventricular repolarization and it is hypothesized that QTc dispersion increases with severity ...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2006-12-01 00:00:00
abstract:AIM:To evaluate the trend of infantile obesity in the school-aged population of Cremona over time. METHODS:The weight and height of all children aged 6, 9 and 11 attending schools within the health district of Cremona were measured for 9 consecutive years (January 1990-March 1998), giving a total of 17,730 measurement...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:The aim of this study is to investigate the use of methylene blue in perioperative identification of the patent processus vaginalis in a group of boys presenting with congenital or recurrent hydrocele where surgery was performed by junior surgeons in training. METHODS:We retrospectively reviewed the notes o...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:10.23736/S0026-4946.17.04661-8
更新日期:2020-04-01 00:00:00
abstract:AIM:The increase in life expectancy of cystic fibrosis (CF) patients has brought about a rise in new clinical problems in these patients, such as a decrease in bone mineral density (BMD). The cause of diminished BMD in CF is multi-factorial. METHODS:The aim of this cross-sectional study, conducted on 39 CF patients un...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2008-04-01 00:00:00
abstract::Little is known about the overlapping symptoms and comorbidity of pediatric bipolar disorder (BD) and pervasive developmental disorders (PDD) in youth. The aim of this study was to clearly differentiate the symptoms, understand the prevalence and patterns of comorbid presentations, as well as to provide a summary of e...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2008-02-01 00:00:00
abstract:AIM:Despite the availability of a number of pharmacological options, relief of allergic rhinitis (AR) symptoms, especially nasal obstruction, is often limited and local and systemic adverse reactions are not infrequent. The main aim of the present pilot study was to provide subjective and objective evidence of the clin...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2015-06-01 00:00:00
abstract:AIM:The aim of this study was to evaluate the influence of colostomy type on morbidity during the treatment of anorectal malformations. METHODS:Sixty-eight infants (male: female ratio 1.3:1) with anorectal malformations that required colostomy were treated in our clinics during the period 1991-2001. Of these patients,...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2004-08-01 00:00:00
abstract::The Authors describe an uncommon case of growth retardation; the clinical and radiological elements that the Authors to a diagnosis of spondyloepiphyseal dysplasia (SED) are noted; they compare this to other diagnosis of different types of growth retardation, they underline the necessity of taking these rare types int...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:1992-07-01 00:00:00
abstract:AIM:The estimation of peak expiratory flow (PEF) in children is a very easy and practical way to check lung function and helps in the diagnosis, treatment follow-up and evaluation of the development of chronic obstructive pulmonary disease. METHODS:Using a Mini-Wright flowmeter (Clement Clarke International Ltd, Engla...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2005-04-01 00:00:00
abstract::Infants born prematurely before 37 weeks of gestational age (GA) have particular anatomical, immunological and metabolic characteristics that predispose them, even in the absence of diseases at birth, to severe morbidity. Respiratory syncytial virus (RSV) is the leading cause of hospitalization for lower respiratory t...
journal_title:Minerva pediatrica
pub_type: 杂志文章,评审
doi:10.23736/S0026-4946.18.05300-8
更新日期:2018-12-01 00:00:00
abstract::Neonatal analgesia is a recent issue: newborns were supposed to feel no pain until the late "80s; but from that date, many studies were performed to verify the extent of neonates" pain perception, ways to measure and overcome it. Pain can have harmful consequences in babies, due to several causes, and we investigated ...
journal_title:Minerva pediatrica
pub_type: 杂志文章,评审
doi:
更新日期:2010-06-01 00:00:00
abstract:BACKGROUND:In the last years thalassemic patients gained a good improvement in prognosis and life style. However, short stature and hypogonadism are still frequent endocrine problems in this population. METHODS:In a group of eleven thalassemic males (14-18 years old), the spontaneous nocturnal endocrine patterns of LH...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:1998-05-01 00:00:00
abstract::Early recognition of shock is the key to successful resuscitation in critically ill children. Often, shock results in or co-exists with myo-cardial dysfunction or acute lung injury. Recognition and appropriate management of these insults is crucial for successful outcomes. Resuscitation should be directed to restorati...
journal_title:Minerva pediatrica
pub_type: 杂志文章,评审
doi:
更新日期:2009-02-01 00:00:00
abstract::Insulin-dependent diabetes mellitus is associated to important micro and macro vascular complications. A good metabolic control can reduce the risk of complications. Aim of the study was to evaluate the metabolic control in adolescent diabetic patients using an educational system with graphic visualisation of capillar...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:1996-06-01 00:00:00
abstract::This paper reports a case of pyloric duplication, an extremely rare abnormality usually discovered during infancy. Clinical findings involved mainly symptoms of obstruction and radiological evaluation included abdominal US, plain radiography and CT imaging. Pyloric duplication was diagnosed by US and confirmed by CT s...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2006-08-01 00:00:00
abstract::Providing optimal mechanical ventilation to critically-ill children remains a challenge. Patient-ventilator dyssynchrony results frequently with numerous deleterious consequences on patient outcome including increased requirement for sedation, prolonged duration of ventilation, and greater imposed work of breathing. M...
journal_title:Minerva pediatrica
pub_type: 杂志文章,评审
doi:
更新日期:2016-12-01 00:00:00