Polycystic ovary syndrome: a common hormonal condition with major metabolic sequelae that physicians should know about.

abstract：BACKGROUND:Immunohistochemistry for loss of expression of one or more of the mismatch repair proteins is performed on colorectal cancer tissue as a screening test for Lynch syndrome; however, its role in pre-malignant polyps remains controversial. AIM:To determine the effectiveness of mismatch repair immunohistochemis...

journal_title：Internal medicine journal

authors： Dow E,Buchanan DD,Winship IM

更新日期：2018-11-01 00:00:00

abstract：:Interaction between doctors and the pharmaceutical industry is long-standing and ingrained in modern practice. Doctors-in-training are at a vulnerable stage of their careers, both in requiring knowledge and forming lasting relationships. There is evidence that limiting contact between industry and junior doctors has a...

journal_title：Internal medicine journal

authors： Pokorny AM,Gittins CB

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:An adequately powered, double-blind, multisite, randomised controlled trial has shown no net clinical benefit for subcutaneous ketamine over placebo in the management of cancer pain refractory to combination opioid and co-analgesic therapy. The results of the trial were disseminated widely both nationally an...

journal_title：Internal medicine journal

authors： Hardy JR,Spruyt O,Quinn SJ,Devilee LR,Currow DC

更新日期：2014-06-01 00:00:00

abstract：:To improve organ donation processes and outcomes, many Australian hospitals have introduced donation after cardiac death (DCD) following the 2010 publication of the National Protocol for DCD. As emergency clinicians play a significant role in identifying potential DCD donors, it is critical to assess their support and...

journal_title：Internal medicine journal

authors： Marck CH,Neate SL,Weiland TJ,Hickey BB,Jelinek GA

更新日期：2013-07-01 00:00:00

abstract：:Transient ischaemic attack (TIA) if untreated carries a high risk of early stroke and is associated with poorer long-term survival. There have been recent advances in the understanding of TIA, its investigations, management and organisation of services for patient care. Clinically, patients are diagnosed TIA if they h...

journal_title：Internal medicine journal

authors： Phan TG,Sanders L,Srikanth V

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND/AIM:This study aimed to report the clinical characteristics and outcomes of Australian patients treated with eculizumab for atypical haemolytic uraemic syndrome (aHUS). METHODS:A retrospective cohort study was undertaken of all patients in Australia treated with eculizumab provided in a compassionate access...

journal_title：Internal medicine journal

authors： Mallett A,Hughes P,Szer J,Tuckfield A,Van Eps C,Cambell SB,Hawley C,Burke J,Kausman J,Hewitt I,Parnham A,Ford S,Isbel N

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Patients who suffer from acute IgE-mediated allergy to a cephalosporin antibiotic are frequently assumed to be at high risk of allergy to other cephalosporins and penicillins. AIM:To define cross-reactivity patterns in patients with confirmed allergy to a cephalosporin. METHODS:Subjects presenting with a h...

journal_title：Internal medicine journal

authors： Yuson C,Kumar K,Le A,Ahmadie A,Banovic T,Heddle R,Kette F,Smith W,Hissaria P

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:Advance care planning (ACP) provides patients with the ability to make their decisions known about how they would like to be treated if they lose capacity. Medical practitioners have a key role to play in providing information on ACP to their patients. This research explores their knowledge and attitudes to ...

journal_title：Internal medicine journal

authors： Cartwright C,Montgomery J,Rhee J,Zwar N,Banbury A

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Infective endocarditis (IE) is a severe infection conferring significant morbidity and mortality. It is associated with geographical variation, complicating diagnosis and treatment of patients in a standardised manner. AIM:To evaluate the presentation, treatment and outcomes of patients with IE in the Hunte...

journal_title：Internal medicine journal

authors： Doig F,Loewenthal M,Lai K,Mejia R,Iyengar A

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:The aim of this study was to describe the activity of a lung cancer multidisciplinary clinic (MDC) and examine whether this model of clinical practice results in adherence to best-practice guidelines. METHODS:Prospective analysis of demographic and clinical data in 431 patients referred to a lung cancer MDC...

journal_title：Internal medicine journal

authors： Conron M,Phuah S,Steinfort D,Dabscheck E,Wright G,Hart D

更新日期：2007-01-01 00:00:00

abstract：:Significant developments have occurred in the discipline of palliative care in the modern era. This paper shall explore those developments, challenge some widely held misconceptions about the role and daily practice of the discipline, highlight the growing recognition of the role of palliative care in non-malignant di...

journal_title：Internal medicine journal

authors： Brennan F

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:A number of haematological malignancies can be cured by allogeneic stem cell transplantation but only approximately 30% of Australians have a suitable histocompatible related donor. Matched donors can be found on international registries of unrelated volunteers for a proportion of the remaining patients. For...

journal_title：Internal medicine journal

authors： Bradstock KF,Hertzberg MS,Kerridge IH,Svennilson J,McGurgan M,Huang G,Antonenas V,Gottlieb DJ

更新日期：2006-06-01 00:00:00

abstract：:Healthcare encompasses multiple discourses to which health professionals, researchers, patients, carers and lay individuals contribute. Networks of patients and non-professionals often act collectively to build capacity, enhance access to resources, develop understanding and improve provision of care. This article exp...

journal_title：Internal medicine journal

authors： Grant MP,Philip JAM,Deliens L,Komesaroff PA

更新日期：2019-09-01 00:00:00

abstract：:Common peroneal neuropathy (CPN) may develop unexpectedly in patients with underlying cancer. To clarify the underlying pathophysiology, clinical and neurophysiological data were prospectively collected from 10 oncology clinic patients referred for neurological assessment after the onset of foot weakness. In all patie...

journal_title：Internal medicine journal

authors： Simon NG,Kiernan MC

更新日期：2012-07-01 00:00:00

abstract：:A patient with pulmonary arterial hypertension secondary to systemic sclerosis was successfully treated with sitaxentan prior to its worldwide withdrawal (because of hepatotoxicity concerns), but then ironically experienced acute hepatic dysfunction during substitute bosentan therapy, and was eventually stabilised on ...

journal_title：Internal medicine journal

authors： Don GW,Joseph F,Celermajer DS,Corte TJ

更新日期：2012-12-01 00:00:00

abstract：AIM:To explore and detail clinical experiences of dabigatran, a novel anticoagulant, after it became available in New Zealand in July 2011. METHODS:A cohort of patients was recruited from Hutt Hospital and the two largest primary care practices in the Hutt Valley region. They were included if they took at least one do...

journal_title：Internal medicine journal

authors： Thorne K,Jayathissa S,Dee S,Briggs N,Taylor J,Reid S,De Silva K,Dean J

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Trends in the incidence of acute myocardial infarction (AMI) provide important information for healthcare providers and can allow for accurate planning of future health needs and targeted interventions in areas with an excess burden of cardiovascular disease. AIM:To investigate the regional variations in AM...

journal_title：Internal medicine journal

authors： Davies AJ,Naudin C,Al-Omary M,Khan A,Oldmeadow C,Jones M,Bastian B,Bhagwandeen R,Fletcher P,Leitch J,Boyle A

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Informed consent is a mainstay of clinical practice, with both moral and legal forces. Material disclosure about extreme treatments, however, is unlikely to convey the full impact of the experience of treatment. Informed consent may be flawed under such circumstances. The aims of this study were to compare e...

journal_title：Internal medicine journal

authors： Little M,Jordens CF,McGrath C,Montgomery K,Lipworth W,Kerridge I

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:While medications may prolong life and prevent morbidity in older people, adverse effects of polypharmacy are increasingly recognised. As patients age and become frail, prescribing may be expected to focus more on symptom control and minimise potentially harmful preventive medication use that confer little b...

journal_title：Internal medicine journal

authors： Ilango S,Pillans P,Peel NM,Scott I,Gray LC,Hubbard RE

更新日期：2017-09-01 00:00:00

abstract：:Echocardiography is the mainstay of cardiovascular diagnostics, and is the most performed test for the evaluation of cardiac function. Critical and costly management decisions are based on quantification of left ventricular volumes and ejection fraction. Recent advances in echocardiography, such as microsphere contras...

journal_title：Internal medicine journal

authors： Hudaverdi M,Hamilton-Craig C,Platts D,Chan J,Burstow DJ

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:Surveillance for colorectal neoplasia in inflammatory bowel disease (IBD) is widely practised despite a lack of convincing mortality reduction. The psychological impact of this approach is largely unexplored. AIM:To examine psychological well-being among IBD subjects undergoing colonoscopic surveillance for...

journal_title：Internal medicine journal

authors： Mountifield R,Bampton P,Prosser R,Mikocka-Walus A,Andrews JM

更新日期：2014-02-01 00:00:00

abstract：:The Australian Clinical Guidelines for Stroke Management 2010 represents an update of the Clinical Guidelines for Stroke Rehabilitation and Recovery (2005) and the Clinical Guidelines for Acute Stroke Management (2007). For the first time, they cover the whole spectrum of stroke, from public awareness and prehospital ...

journal_title：Internal medicine journal

authors： Wright L,Hill KM,Bernhardt J,Lindley R,Ada L,Bajorek BV,Barber PA,Beer C,Golledge J,Gustafsson L,Hersh D,Kenardy J,Perry L,Middleton S,Brauer SG,Nelson MR,National Stroke Foundation Stroke Guidelines Expert Working Group.

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:The relationship between serum triglycerides (TG) level and the risk of coronary heart disease (CHD) mortality remains controversial. AIMS:To evaluate whether TG level is a risk factor for CHD in elderly people from general population, and to look for interactions between TG and other risk factors. METHODS...

journal_title：Internal medicine journal

authors： Mazza A,Tikhonoff V,Schiavon L,Casiglia E

更新日期：2005-10-01 00:00:00

abstract：:Despite the inclusion of investigator-industry pecuniary and non-pecuniary associations in published clinical trials, the benefit of such disclosures may be limited. Two recent pivotal phase III drug studies that raised conflict of interest issues are discussed. It is recommended that in the future, a firewall should ...

journal_title：Internal medicine journal

authors： Carney SL

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Low dose computed tomography (LDCT) screening can reduce lung cancer deaths in high risk individuals yet current Australian guidelines do not recommend screening. Little is known about current screening practices in Australia. METHODS:A survey was distributed to a nationally-representative sample of 4000 Au...

journal_title：Internal medicine journal

authors： Abeyweera PD,Brims FJH,Piccolo F,Lei C,Manners D

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Advanced training in gastroenterology currently consists of 2 years of core training and 1 elective (non-core) year. We surveyed gastroenterologists 2-7 years following completion of training to determine the strengths and weaknesses of their training. METHODS:All gastroenterologists were invited to partici...

journal_title：Internal medicine journal

authors： Leung C,De Cruz P,Jones A,Sliwka G,Bell SJ,Hebbard GS

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:  According to the International Prognostic Scoring System (IPSS), sole +8 is categorized as intermediate cytogenetic subgroup. But as some myelodysplastic syndrome (MDS) patients with +8 perhaps progress quickly to acute leukaemia and have shorter survival, some reports have suggested that +8 should be cate...

journal_title：Internal medicine journal

authors： Ma Y,Wang X,Xu X,Lin G

更新日期：2010-10-01 00:00:00

abstract：:Myocardial perfusion imaging is a relatively new technique in the emergency department management of acute chest pain. With improved sensitivity and specificity compared to traditional methods of risk stratification, an abnormal scan rapidly identifies individuals with acute perfusion abnormalities and allows the appr...

journal_title：Internal medicine journal

authors： Knott JC,Better N

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND:As direct-to-consumer personal genome testing (DTC-PGT) is increasingly available in Australia, knowledge of Australians' perceptions and attitudes towards this technology is needed in order to assess the (potential) impact it might have on the Australian public and healthcare system. AIMS:To explore the kn...

journal_title：Internal medicine journal

authors： Savard J,Mooney-Somers J,Newson AJ,Kerridge I

更新日期：2014-01-01 00:00:00

abstract：:Carbimazole is a drug that is widely used for hyperthyroid disorders, such as Graves' disease. Agranulocytosis is a rare idiosyncratic adverse reaction to the drug which is potentially fatal. This report describes a patient with a history of successfully treated pyoderma gangrenosum, who developed agranulocytosis 3 we...

journal_title：Internal medicine journal

authors： Yip G,Ekinci E,Lee ST,Jerums G,Grossmann M

更新日期：2010-04-01 00:00:00