Abstract:
:Carbimazole is a drug that is widely used for hyperthyroid disorders, such as Graves' disease. Agranulocytosis is a rare idiosyncratic adverse reaction to the drug which is potentially fatal. This report describes a patient with a history of successfully treated pyoderma gangrenosum, who developed agranulocytosis 3 weeks after commencement of carbimazole for Graves' disease. It may give credence to the theory that implicates antineutrophil cytoplasmic antibodies in the pathogenesis of agranulocytosis induced by antithyroid drugs.
journal_name
Intern Med Jjournal_title
Internal medicine journalauthors
Yip G,Ekinci E,Lee ST,Jerums G,Grossmann Mdoi
10.1111/j.1445-5994.2009.02143.xsubject
Has Abstractpub_date
2010-04-01 00:00:00pages
300-3issue
4eissn
1444-0903issn
1445-5994pii
IMJ2143journal_volume
40pub_type
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