Neuronal adaptation involves rapid expansion of the action potential initiation site.

abstract：:Acanthamoeba are infected by a remarkable diversity of large dsDNA viruses, the infectious cycles of which have been characterized using genomics, transcriptomics and electron microscopy. Given their gene content and the persistence of the host nucleus throughout their infectious cycle, the Marseilleviridae were initi...

journal_title：Nature communications

authors： Fabre E,Jeudy S,Santini S,Legendre M,Trauchessec M,Couté Y,Claverie JM,Abergel C

更新日期：2017-04-21 00:00:00

abstract：:Noble metal nanoparticles stabilized by organic ligands are important for applications in assembly, site-specific bioconjugate labelling and sensing, drug delivery and medical therapy, molecular recognition and molecular electronics, and catalysis. Here we report crystal structures and theoretical analysis of three Ag...

journal_title：Nature communications

authors： Yang H,Wang Y,Huang H,Gell L,Lehtovaara L,Malola S,Häkkinen H,Zheng N

更新日期：2013-01-01 00:00:00

abstract：:Selector devices are indispensable components of large-scale nonvolatile memory and neuromorphic array systems. Besides the conventional silicon transistor, two-terminal ovonic threshold switching device with much higher scalability is currently the most industrially favored selector technology. However, current ovoni...

journal_title：Nature communications

authors： Jia S,Li H,Gotoh T,Longeaud C,Zhang B,Lyu J,Lv S,Zhu M,Song Z,Liu Q,Robertson J,Liu M

更新日期：2020-09-15 00:00:00

abstract：:Transition-metal dissolution from cathode materials, manganese in particular, has been held responsible for severe capacity fading in lithium-ion batteries, with the deposition of the transition-metal cations on anode surface, in elemental form or as chelated-complexes, as the main contributor for such degradations. I...

journal_title：Nature communications

authors： Wang C,Xing L,Vatamanu J,Chen Z,Lan G,Li W,Xu K

更新日期：2019-07-31 00:00:00

abstract：:Th9 cells protect hosts against helminthic infection but also mediate allergic disease. Here we show that nitric oxide (NO) promotes Th9 cell polarization of murine and human CD4(+) T cells. NO de-represses the tumour suppressor gene p53 via nitrosylation of Mdm2. NO also increases p53-mediated IL-2 production, STAT5 ...

journal_title：Nature communications

authors： Niedbala W,Besnard AG,Nascimento DC,Donate PB,Sonego F,Yip E,Guabiraba R,Chang HD,Fukada SY,Salmond RJ,Schmitt E,Bopp T,Ryffel B,Liew FY

更新日期：2014-08-07 00:00:00

abstract：:Scleroderma is an autoimmune rheumatic disorder accompanied by severe fibrosis in skin and other internal organs. During scleroderma progression, resident fibroblasts undergo activation and convert to α-smooth muscle actin (α-SMA) expressing myofibroblasts (MFBs) with increased capacity to synthesize collagens and fib...

journal_title：Nature communications

authors： Park JS,Oh Y,Park YJ,Park O,Yang H,Slania S,Hummers LK,Shah AA,An HT,Jang J,Horton MR,Shin J,Dietz HC,Song E,Na DH,Park EJ,Kim K,Lee KC,Roschke VV,Hanes J,Pomper MG,Lee S

更新日期：2019-03-08 00:00:00

abstract：:Diffusion is the result of repeated random scattering. It governs a wide range of phenomena from Brownian motion, to heat flow through window panes, neutron flux in fuel rods, dispersion of light in human tissue, and electronic conduction. It is universally acknowledged that the diffusion approach to describing wave t...

journal_title：Nature communications

authors： Shi Z,Genack AZ

更新日期：2018-05-10 00:00:00

abstract：:Generation of coherent light with desirable amplitude and phase profiles throughout the optical spectrum is a key issue in optical technologies. Nonlinear wavefront shaping offers an exceptional way to achieve this goal by converting an incident light beam into the beam (or beams) of different frequency with spatially...

journal_title：Nature communications

authors： Liu S,Switkowski K,Xu C,Tian J,Wang B,Lu P,Krolikowski W,Sheng Y

更新日期：2019-07-19 00:00:00

abstract：:HIV-1-infected people who take drugs that suppress viremia to undetectable levels are protected from developing AIDS. Nonetheless, HIV-1 establishes proviruses in long-lived CD4+ memory T cells, and perhaps other cell types, that preclude elimination of the virus even after years of continuous antiviral therapy. Here ...

journal_title：Nature communications

authors： McCauley SM,Kim K,Nowosielska A,Dauphin A,Yurkovetskiy L,Diehl WE,Luban J

更新日期：2018-12-13 00:00:00

abstract：:Imaging the optical properties of individual nanosystems beyond fluorescence can provide a wealth of information. However, the minute signals for absorption and dispersion are challenging to observe, and only specialized techniques requiring sophisticated noise rejection are available. Here we use signal enhancement i...

journal_title：Nature communications

authors： Mader M,Reichel J,Hänsch TW,Hunger D

更新日期：2015-06-24 00:00:00

abstract：:When assembling individual quantum components into a mesoscopic circuit, the interplay between Coulomb interaction and charge granularity breaks down the classical laws of electrical impedance composition. Here we explore experimentally the thermal consequences, and observe an additional quantum mechanism of electroni...

journal_title：Nature communications

authors： Sivre E,Duprez H,Anthore A,Aassime A,Parmentier FD,Cavanna A,Ouerghi A,Gennser U,Pierre F

更新日期：2019-12-10 00:00:00

abstract：:Upon muscle injury, the high mobility group box 1 (HMGB1) protein is upregulated and secreted to initiate reparative responses. Here we show that HMGB1 controls myogenesis both in vitro and in vivo during development and after adult muscle injury. HMGB1 expression in muscle cells is regulated at the translational leve...

journal_title：Nature communications

authors： Dormoy-Raclet V,Cammas A,Celona B,Lian XJ,van der Giessen K,Zivojnovic M,Brunelli S,Riuzzi F,Sorci G,Wilhelm BT,Di Marco S,Donato R,Bianchi ME,Gallouzi IE

更新日期：2013-01-01 00:00:00

abstract：:Tradeoffs affect resource allocation during development and result in fitness consequences that drive the evolution of life history strategies. Yet despite their importance, we know little about the mechanisms underlying life history tradeoffs. Many species of Colias butterflies exhibit an alternative life history str...

journal_title：Nature communications

authors： Woronik A,Tunström K,Perry MW,Neethiraj R,Stefanescu C,Celorio-Mancera MP,Brattström O,Hill J,Lehmann P,Käkelä R,Wheat CW

更新日期：2019-12-17 00:00:00

abstract：:Networks of natural protein nanofibrils, such as cytoskeletal filaments, control the shape and the division of cells, yet mimicking this functionality in a synthetic setting has proved challenging. Here, we demonstrate that artificial networks of protein nanofibrils can induce controlled deformation and division of al...

journal_title：Nature communications

authors： Song Y,Michaels TCT,Ma Q,Liu Z,Yuan H,Takayama S,Knowles TPJ,Shum HC

更新日期：2018-05-29 00:00:00

abstract：:Ellagitannins are a family of polyphenols containing more than 1,000 natural products. Nearly 40% of these compounds contain a highly oxygenated diaryl ether that is one of the most critical elements to their structural diversity. Here, we report a unified strategy for the synthesis of highly oxygenated diaryl ethers ...

journal_title：Nature communications

authors： Hirokane T,Hirata Y,Ishimoto T,Nishii K,Yamada H

更新日期：2014-03-24 00:00:00

abstract：:Hundreds of clinical studies have demonstrated associations between the human microbiome and disease, yet fundamental questions remain on how we can generalize this knowledge. Results from individual studies can be inconsistent, and comparing published data is further complicated by a lack of standard processing and a...

journal_title：Nature communications

authors： Duvallet C,Gibbons SM,Gurry T,Irizarry RA,Alm EJ

更新日期：2017-12-05 00:00:00

abstract：:Detecting the metallic Dirac electronic states on the surface of Topological Insulators (TIs) is critical for the study of important surface quantum properties (SQPs), such as Majorana zero modes, where simultaneous probing of the bulk and edge electron states is required. However, there is a particular shortage of ex...

journal_title：Nature communications

authors： Papawassiliou W,Jaworski A,Pell AJ,Jang JH,Kim Y,Lee SC,Kim HJ,Alwahedi Y,Alhassan S,Subrati A,Fardis M,Karagianni M,Panopoulos N,Dolinšek J,Papavassiliou G

更新日期：2020-03-09 00:00:00

abstract：:In bacteria, transcription complexes stalled on DNA represent a major source of roadblocks for the DNA replication machinery that must be removed in order to prevent damaging collisions. Gram-positive bacteria contain a transcription factor HelD that is able to remove and recycle stalled complexes, but it was not know...

journal_title：Nature communications

authors： Newing TP,Oakley AJ,Miller M,Dawson CJ,Brown SHJ,Bouwer JC,Tolun G,Lewis PJ

更新日期：2020-12-18 00:00:00

abstract：:The ionic conductance through a nanometer-sized pore in a membrane changes when a biopolymer slides through it, making nanopores sensitive to single molecules in solution. Their possible use for sequencing has motivated numerous studies on how DNA, a semi-flexible polymer, translocates nanopores. Here we study voltage...

journal_title：Nature communications

authors： McMullen A,de Haan HW,Tang JX,Stein D

更新日期：2014-06-16 00:00:00

abstract：:Blends of electron-donating and -accepting organic semiconductors are widely used as photoactive materials in next-generation solar cells and photodetectors. The yield of free charges in these systems is often determined by the separation of interfacial electron-hole pairs, which is expected to depend on the ability o...

journal_title：Nature communications

authors： Stolterfoht M,Armin A,Shoaee S,Kassal I,Burn P,Meredith P

更新日期：2016-06-21 00:00:00

abstract：:Gap junction channels mediate intercellular signalling that is crucial in tissue development, homeostasis and pathologic states such as cardiac arrhythmias, cancer and trauma. To explore the mechanism by which Ca(2+) blocks intercellular communication during tissue injury, we determined the X-ray crystal structures of...

journal_title：Nature communications

authors： Bennett BC,Purdy MD,Baker KA,Acharya C,McIntire WE,Stevens RC,Zhang Q,Harris AL,Abagyan R,Yeager M

更新日期：2016-01-12 00:00:00

abstract：:The cation channel TRPM8 plays a central role in the somatosensory system, as a key sensor of innocuously cold temperatures and cooling agents. Although increased functional expression of TRPM8 has been implicated in various forms of pathological cold hypersensitivity, little is known about the cellular and molecular ...

journal_title：Nature communications

authors： Ghosh D,Pinto S,Danglot L,Vandewauw I,Segal A,Van Ranst N,Benoit M,Janssens A,Vennekens R,Vanden Berghe P,Galli T,Vriens J,Voets T

更新日期：2016-02-04 00:00:00

abstract：:Two-dimensional atomic crystals, such as two-dimensional oxides, have attracted much attention in energy storage because nearly all of the atoms can be exposed to the electrolyte and involved in redox reactions. However, current strategies are largely limited to intrinsically layered compounds. Here we report a genera...

journal_title：Nature communications

authors： Xiao X,Song H,Lin S,Zhou Y,Zhan X,Hu Z,Zhang Q,Sun J,Yang B,Li T,Jiao L,Zhou J,Tang J,Gogotsi Y

更新日期：2016-04-22 00:00:00

abstract：:It is well known that a topologically protected gapless state appears at an interface between a topological insulator and an ordinary insulator; however, the physics of the interface between a topological insulator and a metal has largely been left unexplored. Here we report a novel phenomenon termed topological proxi...

journal_title：Nature communications

authors： Shoman T,Takayama A,Sato T,Souma S,Takahashi T,Oguchi T,Segawa K,Ando Y

更新日期：2015-03-12 00:00:00

abstract：:The sensitivity of quantum magnetometer is challenged by control errors and, especially in the solid state, by their short coherence times. Refocusing techniques can overcome these limitations and improve the sensitivity to periodic fields, but they come at the cost of reduced bandwidth and cannot be applied to sense ...

journal_title：Nature communications

authors： Aiello CD,Hirose M,Cappellaro P

更新日期：2013-01-01 00:00:00

abstract：:Health risk factors such as body mass index (BMI) and serum cholesterol are associated with many common diseases. It often remains unclear whether the risk factors are cause or consequence of disease, or whether the associations are the result of confounding. We develop and apply a method (called GSMR) that performs a...

journal_title：Nature communications

authors： Zhu Z,Zheng Z,Zhang F,Wu Y,Trzaskowski M,Maier R,Robinson MR,McGrath JJ,Visscher PM,Wray NR,Yang J

更新日期：2018-01-15 00:00:00

abstract：:While molecular water-oxidation catalysts are remarkably rapid, oxidative and hydrolytic processes in water can convert their active transition metals to colloidal metal oxides or hydroxides that, while quite reactive, are insoluble or susceptible to precipitation. In response, we propose using oxidatively-inert ligan...

journal_title：Nature communications

authors： Chakraborty B,Gan-Or G,Raula M,Gadot E,Weinstock IA

更新日期：2018-11-20 00:00:00

abstract：:SCRaMbLE (Synthetic Chromosome Rearrangement and Modification by LoxP-mediated Evolution) is a genome restructuring technique that can be used in synthetic genomes such as that of Sc2.0, the synthetic yeast genome, which contains hundreds to thousands of strategically positioned loxPsym sites. SCRaMbLE has been used t...

journal_title：Nature communications

authors： Shen MJ,Wu Y,Yang K,Li Y,Xu H,Zhang H,Li BZ,Li X,Xiao WH,Zhou X,Mitchell LA,Bader JS,Yuan Y,Boeke JD

更新日期：2018-05-22 00:00:00

abstract：:Van der Waals materials and heterostructures that manifest strongly bound exciton states at room temperature also exhibit emergent physical phenomena and are of great promise for optoelectronic applications. Here, we demonstrate that nanostructured, multilayer transition metal dichalcogenides (TMDCs) by themselves pro...

journal_title：Nature communications

authors： Zhang H,Abhiraman B,Zhang Q,Miao J,Jo K,Roccasecca S,Knight MW,Davoyan AR,Jariwala D

更新日期：2020-07-15 00:00:00

abstract：:Metal halide perovskites feature crystalline-like electronic band structures and liquid-like physical properties. The crystal-liquid duality enables optoelectronic devices with unprecedented performance and a unique opportunity to chemically manipulate the structure with low energy input. In this work, we leverage the...

journal_title：Nature communications

authors： Rosales BA,Mundt LE,Allen TG,Moore DT,Prince KJ,Wolden CA,Rumbles G,Schelhas LT,Wheeler LM

更新日期：2020-10-16 00:00:00