Nonlinear wavefront shaping with optically induced three-dimensional nonlinear photonic crystals.

abstract：:Trimethylation of histone H3 on lysine-4 (H3K4me3) is associated with gene-regulatory elements, but its transcription-independent function in cell division is unclear. CxxC-finger protein-1 (CFP1) is a major mediator of H3K4 trimethylation in mouse oocytes. Here we report that oocyte-specific knockout of Cxxc1, inhibi...

journal_title：Nature communications

authors： Sha QQ,Dai XX,Jiang JC,Yu C,Jiang Y,Liu J,Ou XH,Zhang SY,Fan HY

更新日期：2018-08-28 00:00:00

abstract：:Graphene nanoribbons (GNRs)-narrow stripes of graphene-have emerged as promising building blocks for nanoelectronic devices. Recent advances in bottom-up synthesis have allowed production of atomically well-defined armchair GNRs with different widths and doping. While all experimentally studied GNRs have exhibited wid...

journal_title：Nature communications

authors： Kimouche A,Ervasti MM,Drost R,Halonen S,Harju A,Joensuu PM,Sainio J,Liljeroth P

更新日期：2015-12-14 00:00:00

abstract：:The original version of this article contained an error in the spelling of the author Christian A.M. Wilson, which was incorrectly given as Christian M.A. Wilson. This has now been corrected in both the PDF and HTML versions of the article. ...

journal_title：Nature communications

authors： Bustamante A,Sotelo-Campos J,Guerra DG,Floor M,Wilson CAM,Bustamante C,Báez M

更新日期：2017-12-14 00:00:00

abstract：:Controlled macrophage differentiation and activation in the initiation and resolution of inflammation is crucial for averting progression to chronic inflammatory and autoimmune diseases. Here we show a negative feedback mechanism for proinflammatory IFN-γ activation of macrophages driven by macrophage-associated matri...

journal_title：Nature communications

authors： Dufour A,Bellac CL,Eckhard U,Solis N,Klein T,Kappelhoff R,Fortelny N,Jobin P,Rozmus J,Mark J,Pavlidis P,Dive V,Barbour SJ,Overall CM

更新日期：2018-06-20 00:00:00

abstract：:Non-line-of-sight (NLOS) imaging recovers objects using diffusely reflected indirect light using transient illumination devices in combination with a computational inverse method. While capture systems capable of collecting light from the entire NLOS relay surface can be much more light efficient than single pixel poi...

journal_title：Nature communications

authors： Liu X,Bauer S,Velten A

更新日期：2020-04-02 00:00:00

abstract：:Lysocin E, a 37-membered natural depsipeptide, induces rapid bacteriolysis in methicillin-resistant Staphylococcus aureus via a unique menaquinone-dependent mechanism, presenting a promising therapeutic lead. Despite the great medical importance, exploring the potential utility of its derivatives as new platform struc...

journal_title：Nature communications

authors： Itoh H,Tokumoto K,Kaji T,Paudel A,Panthee S,Hamamoto H,Sekimizu K,Inoue M

更新日期：2019-07-05 00:00:00

abstract：:Tumour cells secrete exosomes that are involved in the remodelling of the tumour-stromal environment and promoting malignancy. The mechanisms governing tumour exosome release, however, remain incompletely understood. Here we show that tumour cell exosomes secretion is controlled by pyruvate kinase type M2 (PKM2), whic...

journal_title：Nature communications

authors： Wei Y,Wang D,Jin F,Bian Z,Li L,Liang H,Li M,Shi L,Pan C,Zhu D,Chen X,Hu G,Liu Y,Zhang CY,Zen K

更新日期：2017-01-09 00:00:00

abstract：:Trade-offs play an important role in evolution. Without trade-offs, evolution would maximize fitness of all traits leading to a "master of all traits". The shape of trade-offs has been shown to determine evolutionary trajectories and is often assumed to be static and independent of the actual evolutionary process. Her...

journal_title：Nature communications

authors： Huang W,Traulsen A,Werner B,Hiltunen T,Becks L

更新日期：2017-12-12 00:00:00

abstract：:Homologous recombination (HR) mediates the error-free repair of DNA double-strand breaks to maintain genomic stability. Here we characterize C17orf53/MCM8IP, an OB-fold containing protein that binds ssDNA, as a DNA repair factor involved in HR. MCM8IP-deficient cells exhibit HR defects, especially in long-tract gene c...

journal_title：Nature communications

authors： Huang JW,Acharya A,Taglialatela A,Nambiar TS,Cuella-Martin R,Leuzzi G,Hayward SB,Joseph SA,Brunette GJ,Anand R,Soni RK,Clark NL,Bernstein KA,Cejka P,Ciccia A

更新日期：2020-06-11 00:00:00

abstract：:Mass extinction events are short-lived and characterized by catastrophic biosphere collapse and subsequent reorganization. Their abrupt nature necessitates a similarly short-lived trigger, and large igneous province magmatism is often implicated. However, large igneous provinces are long-lived compared to mass extinct...

journal_title：Nature communications

authors： Burgess SD,Muirhead JD,Bowring SA

更新日期：2017-07-31 00:00:00

abstract：:The application of electron microscopy to hydrated biological samples has been limited by high-vacuum operating conditions. Traditional methods utilize harsh and laborious sample dehydration procedures, often leading to structural artefacts and creating difficulties for correlating results with high-resolution fluores...

journal_title：Nature communications

authors： Wojcik M,Hauser M,Li W,Moon S,Xu K

更新日期：2015-06-11 00:00:00

abstract：:Metal ions at the active site of an enzyme act as cofactors, and their dynamic fluctuations can potentially influence enzyme activity. Here, we use λ-exonuclease as a model enzyme with two Mg2+ binding sites and probe activity at various concentrations of magnesium by single-molecule-FRET. We find that while MgA2+ and...

journal_title：Nature communications

authors： Hwang W,Yoo J,Lee Y,Park S,Hoang PL,Cho H,Yu J,Hoa Vo TM,Shin M,Jin MS,Park D,Hyeon C,Lee G

更新日期：2018-10-23 00:00:00

abstract：:Chronic kidney disease (CKD) is defined by reduced estimated glomerular filtration rate (eGFR). Previous genetic studies have implicated regulatory mechanisms contributing to CKD. Here we present epigenome-wide association studies of eGFR and CKD using whole-blood DNA methylation of 2264 ARIC Study and 2595 Framingham...

journal_title：Nature communications

authors： Chu AY,Tin A,Schlosser P,Ko YA,Qiu C,Yao C,Joehanes R,Grams ME,Liang L,Gluck CA,Liu C,Coresh J,Hwang SJ,Levy D,Boerwinkle E,Pankow JS,Yang Q,Fornage M,Fox CS,Susztak K,Köttgen A

更新日期：2017-11-03 00:00:00

abstract：:Previous studies have demonstrated that aneuploidy in human embryos is surprisingly frequent with 50-80% of cleavage-stage human embryos carrying an abnormal chromosome number. Here we combine non-invasive time-lapse imaging with karyotypic reconstruction of all blastomeres in four-cell human embryos to address the hy...

journal_title：Nature communications

authors： Chavez SL,Loewke KE,Han J,Moussavi F,Colls P,Munne S,Behr B,Reijo Pera RA

更新日期：2012-01-01 00:00:00

abstract：:PET hydrolase (PETase), which hydrolyzes polyethylene terephthalate (PET) into soluble building blocks, provides an attractive avenue for the bioconversion of plastics. Here we present the structures of a novel PETase from the PET-consuming microbe Ideonella sakaiensis in complex with substrate and product analogs. Th...

journal_title：Nature communications

authors： Han X,Liu W,Huang JW,Ma J,Zheng Y,Ko TP,Xu L,Cheng YS,Chen CC,Guo RT

更新日期：2017-12-13 00:00:00

abstract：:Split spawning in coral populations occurs when gamete maturation and mass spawning are split over two consecutive months. While split spawning has been observed at many reefs, little is known about the frequency and significance of these events. Here we show that split spawning occurred frequently and predictably ove...

journal_title：Nature communications

authors： Foster T,Heyward AJ,Gilmour JP

更新日期：2018-02-19 00:00:00

abstract：:Human social networks are overwhelmingly homophilous: individuals tend to befriend others who are similar to them in terms of a range of physical attributes (e.g., age, gender). Do similarities among friends reflect deeper similarities in how we perceive, interpret, and respond to the world? To test whether friendship...

journal_title：Nature communications

authors： Parkinson C,Kleinbaum AM,Wheatley T

更新日期：2018-01-30 00:00:00

abstract：:In order to model realistic quantum devices it is necessary to simulate quantum systems strongly coupled to their environment. To date, most understanding of open quantum systems is restricted either to weak system-bath couplings or to special cases where specific numerical techniques become effective. Here we present...

journal_title：Nature communications

authors： Strathearn A,Kirton P,Kilda D,Keeling J,Lovett BW

更新日期：2018-08-20 00:00:00

abstract：:Cambodia harbours a variety of aboriginal (and presumably ancient) populations that have largely been ignored in studies of genetic diversity. Here we investigate the matrilineal gene pool of 1,054 Cambodians from 14 geographic populations. Using mitochondrial whole-genome sequencing, we identify eight new mitochondri...

journal_title：Nature communications

authors： Zhang X,Qi X,Yang Z,Serey B,Sovannary T,Bunnath L,Seang Aun H,Samnom H,Zhang H,Lin Q,van Oven M,Shi H,Su B

更新日期：2013-01-01 00:00:00

abstract：:The efficiencies of perovskite solar cells (PSCs) are now reaching such consistently high levels that scalable manufacturing at low cost is becoming critical. However, this remains challenging due to the expensive hole-transporting materials usually employed, and difficulties associated with the scalable deposition of...

journal_title：Nature communications

authors： Wu WQ,Wang Q,Fang Y,Shao Y,Tang S,Deng Y,Lu H,Liu Y,Li T,Yang Z,Gruverman A,Huang J

更新日期：2018-04-24 00:00:00

abstract：:APOBEC3A is a cytidine deaminase driving mutagenesis, DNA replication stress and DNA damage in cancer cells. While the APOBEC3A-induced vulnerability of cancers offers an opportunity for therapy, APOBEC3A protein and mRNA are difficult to quantify in tumors due to their low abundance. Here, we describe a quantitative ...

journal_title：Nature communications

authors： Jalili P,Bowen D,Langenbucher A,Park S,Aguirre K,Corcoran RB,Fleischman AG,Lawrence MS,Zou L,Buisson R

更新日期：2020-06-12 00:00:00

abstract：:Astrocytic endfeet cover the entire cerebral vasculature and serve as exchange sites for ions, metabolites and energy substrates from the blood to the brain. They maintain endothelial tight junctions that form the blood-brain barrier (BBB) and release vasoactive molecules that regulate vascular tone. Malignant gliomas...

journal_title：Nature communications

authors： Watkins S,Robel S,Kimbrough IF,Robert SM,Ellis-Davies G,Sontheimer H

更新日期：2014-06-19 00:00:00

abstract：:When a thin film of active, nematic microtubules and kinesin motor clusters is confined on the surface of a vesicle, four +1/2 topological defects oscillate in a periodic manner between tetrahedral and planar arrangements. Here a theoretical description of nematics, coupled to the relevant hydrodynamic equations, is p...

journal_title：Nature communications

authors： Zhang R,Zhou Y,Rahimi M,de Pablo JJ

更新日期：2016-11-21 00:00:00

abstract：:The current study uses big data to study prosocial behavior by analyzing donations made on the GoFundMe platform. In a dataset of more than $44 million in online donations, we find that 21% were made while opting to be anonymous to the public, with survey results indicating that 11% of these anonymous donations (2.3% ...

journal_title：Nature communications

authors： Sisco MR,Weber EU

更新日期：2019-09-03 00:00:00

abstract：:Mutant Huntingtin (mtHtt) causes neurodegeneration in Huntington's disease (HD) by evoking defects in the mitochondria, but the underlying mechanisms remains elusive. Our proteomic analysis identifies valosin-containing protein (VCP) as an mtHtt-binding protein on the mitochondria. Here we show that VCP is selectively...

journal_title：Nature communications

authors： Guo X,Sun X,Hu D,Wang YJ,Fujioka H,Vyas R,Chakrapani S,Joshi AU,Luo Y,Mochly-Rosen D,Qi X

更新日期：2016-08-26 00:00:00

abstract：:CrAss-like phages are double-stranded DNA viruses that are prevalent in human gut microbiomes. Here, we analyze gut metagenomic data from mother-infant pairs and patients undergoing fecal microbiota transplantation to evaluate the patterns of acquisition, transmission and strain diversity of crAss-like phages. We find...

journal_title：Nature communications

authors： Siranosian BA,Tamburini FB,Sherlock G,Bhatt AS

更新日期：2020-01-15 00:00:00

abstract：:Long-range chromosomal interactions bring distal regulatory elements and promoters together to regulate gene expression in biological processes. By performing promoter capture Hi-C (PCHi-C) on human embryonic stem cell-derived cardiomyocytes (hESC-CMs), we show that such promoter interactions are a key mechanism by wh...

journal_title：Nature communications

authors： Choy MK,Javierre BM,Williams SG,Baross SL,Liu Y,Wingett SW,Akbarov A,Wallace C,Freire-Pritchett P,Rugg-Gunn PJ,Spivakov M,Fraser P,Keavney BD

更新日期：2018-06-28 00:00:00

abstract：:A disturbance of reactive oxygen species (ROS) homeostasis may cause the pathogenesis of many diseases. Inspired by natural photosynthesis, this work proposes a photo-driven H2-evolving liposomal nanoplatform (Lip NP) that comprises an upconversion nanoparticle (UCNP) that is conjugated with gold nanoparticles (AuNPs)...

journal_title：Nature communications

authors： Wan WL,Tian B,Lin YJ,Korupalli C,Lu MY,Cui Q,Wan D,Chang Y,Sung HW

更新日期：2020-01-27 00:00:00

abstract：:Meso/micro-porous solids, such as zeolites, are complex materials used in an impressive range of applications. Here we photo-polymerized ethylene using non-catalytic high-pressure techniques at 0.5-1.5 GPa under ultraviolet (351-364 nm) irradiation on a sub-nanometre scale in the channels of a pure SiO2 zeolite, silic...

journal_title：Nature communications

authors： Santoro M,Gorelli FA,Bini R,Haines J,van der Lee A

更新日期：2013-01-01 00:00:00

abstract：:The ionic conductance through a nanometer-sized pore in a membrane changes when a biopolymer slides through it, making nanopores sensitive to single molecules in solution. Their possible use for sequencing has motivated numerous studies on how DNA, a semi-flexible polymer, translocates nanopores. Here we study voltage...

journal_title：Nature communications

authors： McMullen A,de Haan HW,Tang JX,Stein D

更新日期：2014-06-16 00:00:00