Abstract：
:Mass extinction events are short-lived and characterized by catastrophic biosphere collapse and subsequent reorganization. Their abrupt nature necessitates a similarly short-lived trigger, and large igneous province magmatism is often implicated. However, large igneous provinces are long-lived compared to mass extinctions. Therefore, if large igneous provinces are an effective trigger, a subinterval of magmatism must be responsible for driving deleterious environmental effects. The onset of Earth's most severe extinction, the end-Permian, coincided with an abrupt change in the emplacement style of the contemporaneous Siberian Traps large igneous province, from dominantly flood lavas to sill intrusions. Here we identify the initial emplacement pulse of laterally extensive sills as the critical deadly interval. Heat from these sills exposed untapped volatile-fertile sediments to contact metamorphism, likely liberating the massive greenhouse gas volumes needed to drive extinction. These observations suggest that large igneous provinces characterized by sill complexes are more likely to trigger catastrophic global environmental change than their flood basalt- and/or dike-dominated counterparts.Although the mass end-Permian extinction is linked to large igneous provinces, its trigger remains unclear. Here, the authors propose that the abrupt change from flood lavas to sills resulted in the heating of sediments and led to the release of large-scale greenhouse gases to drive the end-Permian extinction.
journal_name
Nat Communjournal_title
Nature communicationsauthors
Burgess SD,Muirhead JD,Bowring SAdoi
10.1038/s41467-017-00083-9subject
Has Abstractpub_date
2017-07-31 00:00:00pages
164issue
1issn
2041-1723pii
10.1038/s41467-017-00083-9journal_volume
8pub_type
历史文章,杂志文章abstract：:Perovskite quantum-dot-based light-emitting diodes (QLEDs) possess the features of wide gamut and real color expression, which have been considered as candidates for high-quality lightings and displays. However, massive defects are prone to be reproduced during the quantum dot (QD) film assembly, which would sorely af...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-020-17633-3
更新日期：2020-08-06 00:00:00
abstract：:The transcriptional regulatory network (TRN) of Bacillus subtilis coordinates cellular functions of fundamental interest, including metabolism, biofilm formation, and sporulation. Here, we use unsupervised machine learning to modularize the transcriptome and quantitatively describe regulatory activity under diverse co...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-020-20153-9
更新日期：2020-12-11 00:00:00
abstract：:In the original version of this Article, Supplementary Table 10 contained incorrect primer sequences for the mobility shift assay for SNP rs4776984. These errors have now been fixed and the corrected version of the Supplementary Information PDF is available to download from the HTML version of the Article. ...
journal_title：Nature communications
pub_type： 杂志文章,已发布勘误
doi：10.1038/s41467-018-05849-3
更新日期：2018-08-22 00:00:00
abstract：:The maintenance of sensory hair cell stereocilia is critical for lifelong hearing; however, mechanisms of structural homeostasis remain poorly understood. Conflicting models propose that stereocilia F-actin cores are either continually renewed every 24-48 h via a treadmill or are stable, exceptionally long-lived struc...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/ncomms7873
更新日期：2015-04-21 00:00:00
abstract：:The original version of this Article contained errors in Figures 1 and 3. In Fig. 1b, the label 'IP-PBP3' above the second of the three blots incorrectly read 'IP-PBP1B'. In Fig. 3b, the label 'PBP1B' under the first bar of each chart incorrectly read 'PBP1A'. These errors have been corrected in both the PDF and HTML ...
journal_title：Nature communications
pub_type： 杂志文章,已发布勘误
doi：10.1038/s41467-019-08410-y
更新日期：2019-01-30 00:00:00
abstract：:Niobium diselenide has long served as a prototype of two-dimensional charge ordering, believed to arise from an instability of the electronic structure analogous to the one-dimensional Peierls mechanism. Despite this, various anomalous properties have recently been identified experimentally, which cannot be explained ...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/ncomms8034
更新日期：2015-05-07 00:00:00
abstract：:Pair production can be triggered by high-intensity lasers via the Breit-Wheeler process. However, the straightforward laser-laser colliding for copious numbers of pair creation requires light intensities several orders of magnitude higher than possible with the ongoing laser facilities. Despite the numerous proposed a...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/ncomms13686
更新日期：2016-12-14 00:00:00
abstract：:When our experience violates our predictions, it is adaptive to upregulate encoding of novel information, while down-weighting retrieval of erroneous memory predictions to promote an updated representation of the world. We asked whether mnemonic prediction errors promote hippocampal encoding versus retrieval states, a...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-020-17287-1
更新日期：2020-07-10 00:00:00
abstract：:Accurate pathogenicity prediction of missense variants is critically important in genetic studies and clinical diagnosis. Previously published prediction methods have facilitated the interpretation of missense variants but have limited performance. Here, we describe MVP (Missense Variant Pathogenicity prediction), a n...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-020-20847-0
更新日期：2021-01-21 00:00:00
abstract：:Untethered small actuators have various applications in multiple fields. However, existing small-scale actuators are very limited in their intractability with their surroundings, respond to only a single type of stimulus and are unable to achieve programmable structural changes under different stimuli. Here, we presen...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-019-12044-5
更新日期：2019-09-09 00:00:00
abstract：:Melanoma cells use different migratory strategies to exit the primary tumor mass and invade surrounding and subsequently distant tissues. We reported previously that ADAR1 expression is downregulated in metastatic melanoma, thereby facilitating proliferation. Here we show that ADAR1 silencing enhances melanoma cell in...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-018-04600-2
更新日期：2018-05-31 00:00:00
abstract：:Cell competition is an emerging principle that eliminates suboptimal or potentially dangerous cells. For 'unfit' cells to be detected, their competitive status needs to be compared to the collective fitness of cells within a tissue. Here we report that the NMDA receptor controls cell competition of epithelial cells an...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-020-16070-6
更新日期：2020-05-06 00:00:00
abstract：:The Nuclear Pore Complex (NPC) has emerged as an important hub for processing various types of DNA damage. Here, we uncover that fusing a DNA binding domain to the NPC basket protein Nup1 reduces telomere relocalization to nuclear pores early after telomerase inactivation. This Nup1 modification also impairs the reloc...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-019-13979-5
更新日期：2020-01-09 00:00:00
abstract：:Reliable quantum information processing in the face of errors is a major fundamental and technological challenge. Quantum error correction protects quantum states by encoding a logical quantum bit (qubit) in multiple physical qubits. To be compatible with universal fault-tolerant computations, it is essential that sta...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/ncomms11526
更新日期：2016-05-05 00:00:00
abstract：:Streptomycetes are notable for their complex life cycle and production of most clinically important antibiotics. A key factor that controls entry into development and the onset of antibiotic production is the 68-residue protein, BldC. BldC is a putative DNA-binding protein related to MerR regulators, but lacks coiled-...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-018-03576-3
更新日期：2018-03-19 00:00:00
abstract：:The originally published version of this Article contained an error in the spelling of the author Md. Saiful Islam, which was incorrectly given as Saiful Islam. This has now been corrected in both the PDF and HTML versions of the Article. ...
journal_title：Nature communications
pub_type： 杂志文章,已发布勘误
doi：10.1038/s41467-018-04196-7
更新日期：2018-04-23 00:00:00
abstract：:Recent advances in the understanding of spin orbital effects in ultrathin magnetic heterostructures have opened new paradigms to control magnetic moments electrically. The Dzyaloshinskii-Moriya interaction (DMI) is said to play a key role in forming a Néel-type domain wall that can be driven by the spin Hall torque. H...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/ncomms5655
更新日期：2014-08-18 00:00:00
abstract：:An industrial process for the selective activation of methane under mild conditions would be highly valuable for controlling emissions to the environment and for utilizing vast new sources of natural gas. The only selective catalysts for methane activation and conversion to methanol under mild conditions are methane m...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/ncomms11900
更新日期：2016-06-15 00:00:00
abstract：:Conformational dynamics plays an important role in enzyme catalysis, allosteric regulation of protein functions and assembly of macromolecular complexes. Despite these well-established roles, such information has yet to be exploited for drug design. Here we show by nuclear magnetic resonance spectroscopy that inhibito...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/ncomms10638
更新日期：2016-02-25 00:00:00
abstract：:Gene regulation and metabolism are two fundamental processes that coordinate the self-renewal and differentiation of neural precursor cells (NPCs) in the developing mammalian brain. However, little is known about how metabolic signals instruct gene expression to control NPC homeostasis. Here, we show that methylglyoxa...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-020-15941-2
更新日期：2020-04-24 00:00:00
abstract：:This corrects the article DOI: 10.1038/ncomms14454. ...
journal_title：Nature communications
pub_type： 杂志文章,已发布勘误
doi：10.1038/ncomms16007
更新日期：2017-06-23 00:00:00
abstract：:The importance of the tumor-associated stroma in cancer progression is clear. However, it remains uncertain whether early events in the stroma are capable of initiating breast tumorigenesis. Here, we show that in the mammary glands of non-tumor bearing mice, stromal-specific phosphatase and tensin homolog (Pten) delet...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-018-05266-6
更新日期：2018-07-17 00:00:00
abstract：:In vivo electronic monitoring systems are promising technology to obtain biosignals with high spatiotemporal resolution and sensitivity. Here we demonstrate the fabrication of a biocompatible highly conductive gel composite comprising multi-walled carbon nanotube-dispersed sheet with an aqueous hydrogel. This gel comp...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/ncomms11425
更新日期：2016-04-29 00:00:00
abstract：:The mammalian pseudokinase SgK223, and its structurally related homologue SgK269, are oncogenic scaffolds that nucleate the assembly of specific signalling complexes and regulate tyrosine kinase signalling. Both SgK223 and SgK269 form homo- and hetero-oligomers, a mechanism that underpins a diversity of signalling out...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-017-01279-9
更新日期：2017-10-27 00:00:00
abstract：:Macrophages regulate host responses to implants through their dynamic adhesion, release, and activation. Herein, we employ bisphosphonate (BP)-coated gold nanoparticle template (BNP) to direct the swift and convertible formation of Mg2+-functional Mg2+-BP nanoparticle (NP) on the BP-AuNP surface via reversible Mg2+-BP...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-019-09733-6
更新日期：2019-04-12 00:00:00
abstract：:Centrosomes are required for faithful chromosome segregation during mitosis. They are composed of a centriole pair that recruits and organizes the microtubule-nucleating pericentriolar material. Centriole duplication is tightly controlled in vivo and aberrations in this process are associated with several human diseas...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-018-04122-x
更新日期：2018-04-30 00:00:00
abstract：:Controlled macrophage differentiation and activation in the initiation and resolution of inflammation is crucial for averting progression to chronic inflammatory and autoimmune diseases. Here we show a negative feedback mechanism for proinflammatory IFN-γ activation of macrophages driven by macrophage-associated matri...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-018-04717-4
更新日期：2018-06-20 00:00:00
abstract：:Loss of gut mucosal integrity and an aberrant gut microbiota are proposed mechanisms contributing to chronic inflammation and increased morbidity and mortality during antiretroviral-treated HIV disease. Sexual practice has recently been uncovered as a major source of microbiota variation, potentially confounding prior...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-020-16222-8
更新日期：2020-05-15 00:00:00
abstract：:Multi-layer structure of functional materials often involves the integration of different crystalline phases. The film growth orientation thus frequently exhibits a transformation, owing to multiple possibilities caused by incompatible in-plane structural symmetry. Nevertheless, the detailed mechanism of the transform...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-017-01655-5
更新日期：2017-11-14 00:00:00
abstract：:Human endogenous retroviruses (HERV) form a substantial part of the human genome, but mostly remain transcriptionally silent under strict epigenetic regulation, yet can potentially be reactivated by malignant transformation or epigenetic therapies. Here, we evaluate the potential for T cell recognition of HERV element...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-020-19464-8
更新日期：2020-11-09 00:00:00
