当前位置： SCI文献检索 > NUCLEAR MEDICINE AND BIOLOGY期刊下所有文献 > Comparison of trans-1-amino-3-[18F]fluorocyclobutanecarboxylic acid (anti-[18F]FACBC) accumulation in lymph node prostate cancer metastasis and lymphadenitis in rats.

Comparison of trans-1-amino-3-[18F]fluorocyclobutanecarboxylic acid (anti-[18F]FACBC) accumulation in lymph node prostate cancer metastasis and lymphadenitis in rats.

Abstract：

INTRODUCTION:Trans-1-amino-3-[(18)F]fluorocyclobutanecarboxylic acid (anti-[(18)F]FACBC) is a positron emission tomography (PET) tracer used to visualize prostate cancer (PCa). In this study, we investigated the differences in anti-[(18)F]FACBC accumulation between metastatic and inflamed lymph node (LN) lesions. METHODS:A PCa LN metastasis (PLM) model was developed by inoculating a rat PCa cell line, MAT-Ly-Lu-B2, into popliteal LNs of Copenhagen rats. Acute lymphadenitis (AL) was induced by injecting concanavalin A (Con A) into the hind footpad, and chronic lymphadenitis (CL) was induced by daily injection of Con A into the tissues surrounding the popliteal LNs for 2weeks. Main lesions of all animal models were established in lumbar and/or inguinal LNs. Biodistribution and dynamic PET imaging data were acquired after tracer injection. T2-weighted magnetic resonance (MR) images were registered with PET images. RESULTS:In the biodistribution study, the uptake ratios of PLM-to-lymphadenitis in lesional lumbar and inguinal LNs were 0.97-1.57 and 1.47-2.08 at 15 and 60min post-anti-[(18)F]FACBC injection respectively. In PET imaging, the lesional lumbar LNs of CL and PLM, but not of AL, were visualized on anti-[(18)F]FACBC-PET/MR fusion images without disturbance from radioactivity from urine, and　the rank order of anti-[(18)F]FACBC accumulation at 50-60 post-injection in lesional lumbar LNs was PLM>CL>AL. CONCLUSIONS:Anti-[(18)F]FACBC accumulation in LNs with PLM was higher than that in inflamed LNs. ADVANCES IN KNOWLEDGE:The study showed that although low but significant levels of anti-[(18)F]FACBC uptake by chronic inflamed lesions might cause false-positives in anti-[(18)F]FACBC-PET in some PCa patients, uptake of the tracer at acutely inflamed sites was minimal. IMPLICATIONS FOR PATIENT CARE:The findings of this study suggest the potential of Anti-[(18)F]FACBC for distinguishing between tumors and acute inflammation in clinical practice.

journal_name

Nucl Med Biol

journal_title

Nuclear medicine and biology

authors

Kanagawa M,Doi Y,Oka S,Kobayashi R,Nakata N,Toyama M,Shirakami Y

doi

10.1016/j.nucmedbio.2014.04.004

subject

Has Abstract

pub_date

2014-08-01 00:00:00

pages

545-51

issue

7

eissn

0969-8051

issn

1872-9614

pii

S0969-8051(14)00110-3

journal_volume

41

pub_type

杂志文章

相关文献

NUCLEAR MEDICINE AND BIOLOGY文献大全
  • Pharmacokinetic computer simulations of the relationship between in vivo and in vitro neuroreceptor subtype selectivity of radioligands.

    abstract：:Pharmacokinetic computer simulations reveal a discrepancy between the in vivo and in vitro neuroreceptor subtype selectivity of radioligands. For radioligands with an in vitro neuroreceptor subtype selectivity between 0.1 and 10.0, the in vivo neuroreceptor subtype selectivity appears to be constrained to be between 0...

    journal_title：Nuclear medicine and biology

    pub_type： 杂志文章

    doi：10.1016/s0969-8051(99)00061-x

    authors： Zeeberg BR

    更新日期：1999-10-01 00:00:00

  • Evaluation of 99mTc-mercaptoacetyltriglycine-biocytin as a new hepatobiliary imaging agent in mice coinjected with bilirubin.

    abstract：:We evaluated 99mTc-labeled mercaptoacetyltriglycine (99mTc-MAG3)-biocytin as a hepatobiliary imaging agent in the absence and presence of bilirubin in mice. We then compared its pharmacokinetic parameters; peak liver/heart activity ratio (rmax) and half clearance time (HCT) with those of 99mTc-labeled diisopropyl-imin...

    journal_title：Nuclear medicine and biology

    pub_type： 杂志文章

    doi：10.1016/s0969-8051(98)00077-8

    authors： Kim M,Seidel J,Le N,Kim IS,Yoo TM,Barker C,Kobayashi H,Green MV,Carrasquillo JA,Paik CH

    更新日期：1999-01-01 00:00:00

  • [1-11C]octanoate as a potential PET tracer for studying glial functions: PET evaluation in rats and cats.

    abstract：:To evaluate the ability of [1-11C]octanoate as a PET tracer for imaging the brain, we examined its distribution in the brain and surrounding tissues in rats and cats with PET. In rats, owing to the accumulated radioactivity in the harderian glands, clear brain images were not obtained at rostral levels. In cats, the b...

    journal_title：Nuclear medicine and biology

    pub_type： 杂志文章

    doi：10.1016/s0969-8051(96)00148-5

    authors： Kuge Y,Kawashima H,Yamazaki S,Hashimoto N,Miyake Y

    更新日期：1996-11-01 00:00:00

  • Micromethod for quantification of SH groups generated after reduction of monoclonal antibodies.

    abstract：:A simple, rapid, and reproducible micromethod for quantification of sulfhydryl (SH) groups generated after reduction of monoclonal antibody (MAb) disulfide bonds with 2-mercaptoethanol (2-ME) is described. The number of SH groups per molecule of antibody in the 2-ME and in the other reducing agents was calculated from...

    journal_title：Nuclear medicine and biology

    pub_type： 杂志文章

    doi：10.1016/0969-8051(96)00028-5

    authors： Iznaga Escobar N,Morales A,Núñez G

    更新日期：1996-07-01 00:00:00

  • Measurement of glucose metabolism in rat spinal cord slices with dynamic positron autoradiography.

    abstract：:We attempted to measure the regional metabolic rate of glucose (MRglc) in sliced spinal cords in vitro. The thoracic spinal cord of a mature Wister rat was cut into 400-mum slices in oxygenated and cooled (1-4 degrees C) Krebs-Ringer solution. After at least 60 min of preincubation, the spinal cord slices were transfe...

    journal_title：Nuclear medicine and biology

    pub_type： 杂志文章

    doi：10.1016/j.nucmedbio.2008.11.011

    authors： Fan X,Asai T,Morioka K,Uchida K,Baba H,Tanaka K,Zhuang J,Okazawa H,Fujibayashi Y

    更新日期：2009-02-01 00:00:00

  • PET imaging detection of macrophages with a formyl peptide receptor antagonist.

    abstract：:Macrophages are a major inflammatory cell type involved in the development and progression of many important chronic inflammatory diseases. We previously found that apolipoprotein E-deficient (Apoe(-/-)) mice with the C57BL/6 (B6) background develop type 2 diabetes mellitus (T2DM) and accelerated atherosclerosis when ...

    journal_title：Nuclear medicine and biology

    pub_type： 杂志文章

    doi：10.1016/j.nucmedbio.2014.12.001

    authors： Zhang Y,Kundu B,Zhong M,Huang T,Li J,Chordia MD,Chen MH,Pan D,He J,Shi W

    更新日期：2015-04-01 00:00:00

  • Production of Zr-89 using sputtered yttrium coin targets 89Zr using sputtered yttrium coin targets.

    abstract：:An increasing interest in zirconium-89 (89Zr) can be attributed to the isotope's half-life which is compatible with antibody imaging using positron emission tomography (PET). The goal of this work was to develop an efficient means of production for 89Zr that provides this isotope with high radionuclidic purity and spe...

    journal_title：Nuclear medicine and biology

    pub_type： 杂志文章

    doi：10.1016/j.nucmedbio.2017.03.004

    authors： Queern SL,Aweda TA,Massicano AVF,Clanton NA,El Sayed R,Sader JA,Zyuzin A,Lapi SE

    更新日期：2017-07-01 00:00:00

  • Comparison of (18)F-FET and (18)F-FDG PET in brain tumors.

    abstract：UNLABELLED:The purpose of this study was to compare the diagnostic value of positron emission tomography (PET) using [(18)F]-fluorodeoxyglucose ((18)F-FDG) and O-(2-[(18)F]fluoroethyl)-l-tyrosine ((18)F-FET) in patients with brain lesions suspicious of cerebral gliomas. METHODS:Fifty-two patients with suspicion of cer...

    journal_title：Nuclear medicine and biology

    pub_type： 临床试验,杂志文章

    doi：10.1016/j.nucmedbio.2009.05.005

    authors： Pauleit D,Stoffels G,Bachofner A,Floeth FW,Sabel M,Herzog H,Tellmann L,Jansen P,Reifenberger G,Hamacher K,Coenen HH,Langen KJ

    更新日期：2009-10-01 00:00:00

  • Humanized versus murine anti-human epidermal growth factor receptor monoclonal antibodies for immunoscintigraphic studies.

    abstract：:The anti-human epidermal growth factor receptor (EGF-R) humanized antibody h-R3 (IgG(1)), which binds to an extracellular domain of EGF-R, was used to evaluate the biodistribution on nude mice xenografted with A431 epidermoid carcinoma cell line. Results are compared with its murine version ior egf/r3 monoclonal antib...

    journal_title：Nuclear medicine and biology

    pub_type： 杂志文章

    doi：10.1016/s0969-8051(99)00094-3

    authors： Morales AA,Ducongé J,Alvarez-Ruiz D,Becquer-Viart ML,Núñez-Gandolff G,Fernández E,Caballero-Torres I,Iznaga-Escobar N

    更新日期：2000-02-01 00:00:00

  • 2-[18F]Fluoro-A-85380, an in vivo tracer for the nicotinic acetylcholine receptors.

    abstract：:The in vivo brain regional distribution of 2-[18F]fluoro-A-85380, a novel tracer for positron emission tomographic (PET) studies, followed the regional densities of brain nAChRs reported in the literature. Evidence of binding to nAChRs and high specificity of the binding in vivo was demonstrated by inhibition with nAC...

    journal_title：Nuclear medicine and biology

    pub_type： 杂志文章

    doi：10.1016/s0969-8051(98)00031-6

    authors： Horti AG,Scheffel U,Koren AO,Ravert HT,Mathews WB,Musachio JL,Finley PA,London ED,Dannals RF

    更新日期：1998-10-01 00:00:00

  • PET imaging of dopamine transporters with [(18)F]FE-PE2I: Effects of anti-Parkinsonian drugs.

    abstract：PURPOSE:This study aimed to assess the striatal [(18)F]FE-PE2I binding and the immunohistochemical stain of tyrosine hydroxylase (TH) in the striatum, and to evaluate the effects of therapeutic drugs on [(18)F]FE-PE2I binding. METHODS:Dynamic PET/CT of [(18)F]FE-PE2I was performed in Parkinson's disease (PD) rat model...

    journal_title：Nuclear medicine and biology

    pub_type： 杂志文章

    doi：10.1016/j.nucmedbio.2015.11.002

    authors： Bang JI,Jung IS,Song YS,Park HS,Moon BS,Lee BC,Kim SE

    更新日期：2016-02-01 00:00:00

  • Use of PET and the radioligand [carbonyl-(11)C]WAY-100635 in psychotropic drug development.

    abstract：:Positron-emission tomography (PET) provides potential in neuropsychiatric drug development by expanding knowledge of drug action in the living human brain and reducing time consumption and costs. The 5-hydroxytryptamine(1A) (5-HT(1A)) receptor is of central interest as a target for the treatment of anxiety, depression...

    journal_title：Nuclear medicine and biology

    pub_type： 杂志文章

    doi：10.1016/s0969-8051(00)00121-9

    authors： Andrée B,Halldin C,Thorberg SO,Sandell J,Farde L

    更新日期：2000-07-01 00:00:00

  • Development of rapid multistep carbon-11 radiosynthesis of the myeloperoxidase inhibitor AZD3241 to assess brain exposure by PET microdosing.

    abstract：INTRODUCTION:The myeloperoxidase inhibitor AZD3241 has been selected as a candidate drug currently being developed to delay progression in patients with neurodegenerative brain disorders. Part of the decision tree for translation of AZD3241 into clinical studies included the need for assessment of brain exposure in non...

    journal_title：Nuclear medicine and biology

    pub_type： 杂志文章

    doi：10.1016/j.nucmedbio.2015.02.001

    authors： Johnström P,Bergman L,Varnäs K,Malmquist J,Halldin C,Farde L

    更新日期：2015-06-01 00:00:00

  • A new approach to labeling cells with technetium-99m, Part II. Evaluation of radiolabeled human-lymphocyte immune functions.

    abstract：:Technetium-99m-modified polylysine (MPL) is a mild and efficient method for cell labeling that is easily applicable to human lymphocytes. 99mTc-MPL uptake is maximal in 40 min at room temperature. Cell labeling efficiency (from 60 to 80%) increases with rising concentrations of cells and labeling agent. In vitro stabi...

    journal_title：Nuclear medicine and biology

    pub_type： 杂志文章

    doi：10.1016/0969-8051(95)02011-x

    authors： Delmon-Moingeon LI,Mahmood A,Davison A,Jones AG

    更新日期：1996-01-01 00:00:00

  • Investigation of four (99m)Tc-labeled bacteriophages for infection-specific imaging.

    abstract：INTRODUCTION:This study investigated radiolabeled bacteriophages for specific detection of infection through gamma imaging. Previously, a (99m)Tc-labeled M13 phage demonstrated specific binding for its host Escherichia coli in vitro and in mice through imaging. METHODS:This study was extended to phages P22, E79, VD-13...

    journal_title：Nuclear medicine and biology

    pub_type： 杂志文章

    doi：10.1016/j.nucmedbio.2008.02.011

    authors： Rusckowski M,Gupta S,Liu G,Dou S,Hnatowich DJ

    更新日期：2008-05-01 00:00:00

  • Toward realization of 'mix-and-use' approach in ⁶⁸Ga radiopharmacy: preparation, evaluation and preliminary clinical utilization of ⁶⁸Ga-labeled NODAGA-coupled RGD peptide derivative.

    abstract：INTRODUCTION:The present article demonstrates a 'mix-and-use' approach for radiolabeling RGD peptide derivative with (68)Ga, which is easily adaptable in hospital radiopharmacy practice. The radiotracer thus formulated was successfully used for positron emission tomography (PET) imaging of breast cancer in human patien...

    journal_title：Nuclear medicine and biology

    pub_type： 杂志文章

    doi：10.1016/j.nucmedbio.2015.09.010

    authors： Chakraborty S,Chakravarty R,Vatsa R,Bhusari P,Sarma HD,Shukla J,Mittal BR,Dash A

    更新日期：2016-01-01 00:00:00

  • Investigation into 64Cu-labeled Bis(selenosemicarbazone) and Bis(thiosemicarbazone) complexes as hypoxia imaging agents.

    abstract：BACKGROUND:Cu-diacetyl-bis(N4-methylthiosemicarbazone) [Cu-ATSM], although excellent for oncology applications, may not be suitable for delineating cardiovascular or neurological hypoxia. For this reason, new Cu hypoxia positron emission tomography (PET) imaging agents are being examined to search for a higher selectiv...

    journal_title：Nuclear medicine and biology

    pub_type： 杂志文章

    doi：10.1016/j.nucmedbio.2004.10.004

    authors： McQuade P,Martin KE,Castle TC,Went MJ,Blower PJ,Welch MJ,Lewis JS

    更新日期：2005-02-01 00:00:00

  • Fluorine-18-labeled fluorine gas for synthesis of tracer molecules.

    abstract：:The aim of this work was to develop a method to produce 18F-labeled fluorine gas ([18F]F2) with high specific radioactivity (SA, radioactivity/mass-ratio). 18F-Labeled methyl fluoride ([18F]CH3F) was synthesized from [18F]F-aq and mixed with carrier F2 in an inert neon matrix. The constituents were atomized in an elec...

    journal_title：Nuclear medicine and biology

    pub_type： 杂志文章

    doi：10.1016/s0969-8051(97)00078-4

    authors： Bergman J,Solin O

    更新日期：1997-10-01 00:00:00

  • Synthesis of fluorine-18-labeled ciprofloxacin for PET studies in humans.

    abstract：:Ciprofloxacin (1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-quinoline-3-carboxylic acid), a widely-prescribed antibiotic, was labeled with fluorine-18 with the aim to perform positron emission tomography studies in humans for pharmacokinetic measurements. Due to a lack of chemical activation of ciproflox...

    journal_title：Nuclear medicine and biology

    pub_type： 杂志文章

    doi：10.1016/s0969-8051(02)00444-4

    authors： Langer O,Mitterhauser M,Brunner M,Zeitlinger M,Wadsak W,Mayer BX,Kletter K,Müller M

    更新日期：2003-04-01 00:00:00

  • Radiosynthesis and biological evaluation of alpha-[F-18]fluoromethyl phenylalanine for brain tumor imaging.

    abstract：OBJECTIVES:Radiolabeled amino acids have proven utility for imaging brain tumors in humans, particularly those that target system L amino acid transport. We have prepared the novel phenylalanine analogue, (FMePhe, 9), as part of an effort to develop new system L tracers that can be prepared in high radiochemical yield ...

    journal_title：Nuclear medicine and biology

    pub_type： 杂志文章

    doi：10.1016/j.nucmedbio.2012.12.013

    authors： Huang C,Yuan L,Rich KM,McConathy J

    更新日期：2013-05-01 00:00:00

  • Evaluation of [11C]KB631 as a PET tracer for in vivo visualisation of HDAC6 in B16.F10 melanoma.

    abstract：INTRODUCTION:HDAC6, a structural and functional distinct member of the HDAC-family, shows great promise as a target to treat several cancers and neurodegenerative diseases. Several clinical trials are evaluating HDAC6 inhibitors in solid tumours and haematological malignancies, but so far no HDAC6 inhibitor has receive...

    journal_title：Nuclear medicine and biology

    pub_type： 杂志文章

    doi：10.1016/j.nucmedbio.2019.05.004

    authors： Vermeulen K,Ahamed M,Luyten K,Bormans G

    更新日期：2019-01-01 00:00:00

  • An electrochemical approach for removal of radionuclidic contaminants of Eu from 153Sm for effective use in metastatic bone pain palliation.

    abstract：INTRODUCTION:Thermal neutron activation of 152Sm [152Sm(n,γ)153Sm] using natural or isotopically enriched (by 152Sm) samarium target is the established route for production of 153Sm used for preparation of 153Sm-EDTMP for pain palliation in cancer patients with disseminated bone metastases. However, some long-lived rad...

    journal_title：Nuclear medicine and biology

    pub_type： 杂志文章

    doi：10.1016/j.nucmedbio.2017.11.010

    authors： Chakravarty R,Chakraborty S,Khan MS,Ram R,Sarma HD,Dash A

    更新日期：2018-03-01 00:00:00

  • Metabolism of receptor targeted 111In-DTPA-glycoproteins: identification of 111In-DTPA-epsilon-lysine as the primary metabolic and excretory product.

    abstract：:The hepatic and renal retention of indium-111 (111In) from 111In-labeled polypeptides has been the subject of many investigations. Because the lysosome is a common intracellular destination for the degradation of polypeptides, we studied the lysosomal metabolism of 111In-DTPA-labeled glycoproteins targeted to cell sur...

    journal_title：Nuclear medicine and biology

    pub_type： 杂志文章

    doi：10.1016/0969-8051(94)90174-0

    authors： Franano FN,Edwards WB,Welch MJ,Duncan JR

    更新日期：1994-11-01 00:00:00

  • Evaluation of nitrogen-rich macrocyclic ligands for the chelation of therapeutic bismuth radioisotopes.

    abstract：INTRODUCTION:The use of α-emitting isotopes for radionuclide therapy is a promising treatment strategy for small micro-metastatic disease. The radioisotope (213)Bi is a nuclide that has found substantial use for targeted α-therapy (TAT). The relatively unexplored aqueous chemistry of Bi(3+), however, hinders the develo...

    journal_title：Nuclear medicine and biology

    pub_type： 杂志文章

    doi：10.1016/j.nucmedbio.2014.12.007

    authors： Wilson JJ,Ferrier M,Radchenko V,Maassen JR,Engle JW,Batista ER,Martin RL,Nortier FM,Fassbender ME,John KD,Birnbaum ER

    更新日期：2015-05-01 00:00:00

  • Synthesis, characterization and theranostic evaluation of Indium-111 labeled multifunctional superparamagnetic iron oxide nanoparticles.

    abstract：:Indium-111 labeled, Trastuzumab-Doxorubicin Conjugated, and APTES-PEG coated magnetic nanoparticles were designed for tumor targeting, drug delivery, controlled drug release, and dual-modal tumor imaging. Superparamagnetic iron oxide nanoparticles (SPIONs) were synthesized by thermal decomposition method to obtain nar...

    journal_title：Nuclear medicine and biology

    pub_type： 杂志文章

    doi：10.1016/j.nucmedbio.2014.09.007

    authors： Zolata H,Abbasi Davani F,Afarideh H

    更新日期：2015-02-01 00:00:00

  • [125/123I] 5-Iodo-3-pyridyl ethers. syntheses and binding to neuronal nicotinic acetylcholine receptors.

    abstract：:Three 3-pyridyl ether nicotinic ligands-(S)-5-Iodo-3-[(2-pyrrolidinyl)-methoxy]pyridine (5-iodo-A-85865), (S)-5-Iodo-3-[1-(methyl)-2-pyrrolidinyl-methoxy]pyridine (5-Iodo-A-84543), and (S)-5-iodo-3-[1-methyl-(2-azetidinyl)-methoxy]pyridine (5-iodo-N-Me-A-85380) were labeled with I-125/I-123, and their ability to label...

    journal_title：Nuclear medicine and biology

    pub_type： 杂志文章

    doi：10.1016/s0969-8051(01)00258-x

    authors： Fan H,Scheffel UA,Rauseo P,Xiao Y,Dogan AS,Yokoi F,Hilton J,Kellar KJ,Wong DF,Musachio JL

    更新日期：2001-11-01 00:00:00

  • 11C-5-hydroxytryptophan positron emission tomography after radiofrequency ablation of neuroendocrine tumor liver metastases.

    abstract：AIM:The aim was to assess the feasibility of (11)C-5-hydroxy-tryptophan positron emission tomography ((11)C-5-HTP-PET) in the follow-up after radiofrequency ablation (RFA) of liver metastases from neuroendocrine tumors (NETs). BACKGROUND:Contrast-enhanced computed tomography (CECT) and contrast-enhanced ultrasound (CE...

    journal_title：Nuclear medicine and biology

    pub_type： 临床试验,杂志文章

    doi：10.1016/j.nucmedbio.2011.12.013

    authors： Norlén O,Nilsson A,Krause J,Stålberg P,Hellman P,Sundin A

    更新日期：2012-08-01 00:00:00

  • Rhodium-105 tetrathioether complexes: radiochemistry and initial biological evaluation.

    abstract：:105Rhodium(III) complexes with three different acyclic tetrathioether ligands containing pendant carboxylic acid groups have been synthesized and characterized. The complexes were evaluated for stability under physiological conditions and the most promising complexes were evaluated in vivo in normal mice. The primary ...

    journal_title：Nuclear medicine and biology

    pub_type： 杂志文章

    doi：10.1016/s0969-8051(99)00070-0

    authors： Goswami N,Higginbotham C,Volkert W,Alberto R,Nef W,Jurisson S

    更新日期：1999-11-01 00:00:00

  • Synthesis and in vivo evaluation of [O-methyl-11C](2R,4R)-4-hydroxy-2-[2-[2-[2-(3-methoxy)phenyl]ethyl]phenoxy]ethyl-1-methylpyrrolidine as a 5-HT2A receptor PET ligand.

    abstract：:The serotonin2A (5-HT2A) receptor is implicated in the pathophysiology of schizophrenia and mood disorders, and in vivo studies of this receptor would be of value in studying the pathophysiology of these disorders and in measuring the relationship of clinical response to receptor occupancy for 5-HT2A antagonists such ...

    journal_title：Nuclear medicine and biology

    pub_type： 杂志文章

    doi：10.1016/j.nucmedbio.2006.02.001

    authors： Kumar JS,Prabhakaran J,Erlandsson K,Majo VJ,Simpson NR,Pratap M,Van Heertum RL,Mann JJ,Parsey RV

    更新日期：2006-05-01 00:00:00

  • Functional comparison of annexin V analogues labeled indirectly and directly with iodine-124.

    abstract：:We are interested in imaging cell death in vivo using annexin V radiolabeled with (124)I. In this study, [(124)I]4IB-annexin V and [(124)I]4IB-ovalbumin were made using [(124)I]N-hydroxysuccinimidyl-4-iodobenzoate prepared by iododestannylation of N-hydroxysuccinimidyl-4-(tributylstannyl)benzoate. [(124)I]4IB-annexin ...

    journal_title：Nuclear medicine and biology

    pub_type： 杂志文章

    doi：10.1016/j.nucmedbio.2005.02.002

    authors： Dekker B,Keen H,Shaw D,Disley L,Hastings D,Hadfield J,Reader A,Allan D,Julyan P,Watson A,Zweit J

    更新日期：2005-05-01 00:00:00