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The GNAS1 gene in myelodysplastic syndromes (MDS).

Abstract：

:GNAS1 gene is located at the long arm of chromosome 20 (q13.32). GNAS1 gene deletion has never been investigated in MDS. A GNAS1 activating mutation (R201) was recently found in MDS. We applied FISH and DHPLC plus sequencing to investigate GNAS1 gene in MDS cases with and without del(20q) at karyotype.

journal_name

Leuk Res

journal_title

Leukemia research

authors

Di Giacomo D,Lema Fernandez AG,Pierini T,Crescenzi B,Brandimarte L,Matteucci C,Testoni N,Mecucci C

doi

10.1016/j.leukres.2014.03.017

subject

Has Abstract

pub_date

2014-07-01 00:00:00

pages

804-7

issue

7

eissn

0145-2126

issn

1873-5835

pii

S0145-2126(14)00092-7

journal_volume

38

pub_type

杂志文章

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