Abstract：
:Analysis of volatile organic compounds (VOCs) is a promising approach for non-invasive, fast and potentially inexpensive diagnostics. Here, we present a new methodology for profiling the body chemistry by using the volatile fraction of molecules in various body fluids. Using mass spectrometry and cross-reactive nanomaterial-based sensors array, we demonstrate that simultaneous VOC detection from breath and skin would provide complementary, non-correlated information of the body's volatile metabolites profile. Eventually with further wide population validation studies, such a methodology could provide more accurate monitoring of pathological changes compared to the information provided by a single body fluid. The qualitative and quantitative methods presented here offers a variety of options for novel mapping of the metabolic properties of complex organisms, including humans.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Broza YY,Zuri L,Haick Hdoi
10.1038/srep04611subject
Has Abstractpub_date
2014-04-09 00:00:00pages
4611issn
2045-2322pii
srep04611journal_volume
4pub_type
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