Abstract:
:GTPase immune-associated proteins (Gimap) genes encode evolutionarily conserved GTP-binding proteins that are preferentially expressed in immune cells. Specific members have been shown to be involved in lymphocyte development, or are associated with inflammatory and autoimmune diseases. However, the function of these proteins remains poorly understood, both at the cellular and molecular levels. A new study in this issue of the European Journal of Immunology [Eur. J. Immunol. 2014. 44: 561-572] points to the distinct but partly overlapping functions of two members of this family, Gimap3 and Gimap5, and offers new insight into their potential functions in T cells.
journal_name
Eur J Immunoljournal_title
European journal of immunologyauthors
Ciucci T,Bosselut Rdoi
10.1002/eji.201344375subject
Has Abstractpub_date
2014-02-01 00:00:00pages
348-51issue
2eissn
0014-2980issn
1521-4141journal_volume
44pub_type
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