Seroepidemiologic survey of captive Old-World primates for antibodies to human and simian retroviruses, and isolation of a lentivirus from sooty mangabeys (Cercocebus atys).

abstract：:The karyotypes of cells from 10 Burkitt lymphoma (BL) biopsies, eight cell lines established from BL and nine cell lines from non-BL sources were studied by chromosome banding techniques. With the exception of the BL-derived cell lines BJAB, GC-BJAB, Maku and U-8691 all biopsies and lines of Burkitt origin contained a...

journal_title：International journal of cancer

authors： Zech L,Haglund U,Nilsson K,Klein G

更新日期：1976-01-15 00:00:00

abstract：:Studies in human, animal and cellular systems suggest that phenols from virgin olive oil are capable of inhibiting several stages in carcinogenesis, including metastasis. The invasion cascade comprises cell attachment to extracellular matrix components or basement membrane, degradation of basement membrane by proteoly...

journal_title：International journal of cancer

authors： Hashim YZ,Rowland IR,McGlynn H,Servili M,Selvaggini R,Taticchi A,Esposto S,Montedoro G,Kaisalo L,Wähälä K,Gill CI

更新日期：2008-02-01 00:00:00

abstract：:Human lymphoblastoid interferon inhibited the growth in vitro of fibroblasts and epithelial cells from normal, hyperplastic and neoplastic human breast tissue. At an interferon concentration of 10(3) inter-national units (IU) per ml, the inhibitory effects on monolayer growth were completely reversible but the growth ...

journal_title：International journal of cancer

authors： Balkwill F,Watling D,Taylor-Papadimitriou J

更新日期：1978-09-15 00:00:00

abstract：:Extensive hypermethylation and consecutive transcriptional silencing of tumorsuppressor genes have been documented in multiple tumor entities including breast cancer. In a microarray based genome-wide methylation analysis of five sporadic breast carcinomas we identified a hypermethylated CpG island within the first in...

journal_title：International journal of cancer

authors： Versmold B,Felsberg J,Mikeska T,Ehrentraut D,Köhler J,Hampl JA,Röhn G,Niederacher D,Betz B,Hellmich M,Pietsch T,Schmutzler RK,Waha A

更新日期：2007-08-01 00:00:00

abstract：:We report a population based case-control study of exposure to pesticides as risk factor for non-Hodgkin lymphoma (NHL). Male and female subjects aged 18-74 years living in Sweden were included during December 1, 1999, to April 30, 2002. Controls were selected from the national population registry. Exposure to differe...

journal_title：International journal of cancer

authors： Eriksson M,Hardell L,Carlberg M,Akerman M

更新日期：2008-10-01 00:00:00

abstract：:We aimed to determine the prognostic values of 39 circulating cytokines in Chinese patients with metastatic colorectal cancer (CRC) and to develop a novel cytokine-based prognostic classifier (CBPC) for prognostic prediction. A total of 176 patients were divided into two cohorts based on the date of first-line chemoth...

journal_title：International journal of cancer

authors： Chen ZY,He WZ,Peng LX,Jia WH,Guo RP,Xia LP,Qian CN

更新日期：2015-02-01 00:00:00

abstract：:This study profiles testicular cancer incidence and mortality across Europe, and the effects of age, period and generational influences, using age-period-cohort modeling. Despite a 5-fold variation in incidence rates, there were consistent mean increases in incidence in each of the 12 European countries studied, rangi...

journal_title：International journal of cancer

authors： Bray F,Richiardi L,Ekbom A,Pukkala E,Cuninkova M,Møller H

更新日期：2006-06-15 00:00:00

abstract：:Therapeutic effectiveness against metastatic or even locally advanced pancreatic ductal adenocarcinoma (PDAC) is dismal, with 5-year survival less than 5%. Even in patients who undergo potentially curative resection, most patients' tumors recur in the liver. Improving therapies targeting or preventing liver metastases...

journal_title：International journal of cancer

authors： Kurahara H,Bohl C,Natsugoe S,Nishizono Y,Harihar S,Sharma R,Iwakuma T,Welch DR

更新日期：2016-08-01 00:00:00

abstract：:Recently, pegylated arginine deiminase (ADI; EC 3.5.3.6) has been used to treat the patients with hepatocellular carcinoma or melanoma, in which the level of argininosuccinate synthetase (ASS) activity is low or undetectable. The efficacy of its antitumor activity largely depends on the level of intracellular ASS, whi...

journal_title：International journal of cancer

authors： Yoon CY,Shim YJ,Kim EH,Lee JH,Won NH,Kim JH,Park IS,Yoon DK,Min BH

更新日期：2007-02-15 00:00:00

abstract：:Treatment of mouse Lewis lung carcinoma with razoxane or dacarbazine was protracted for 10 transplant generations. While the capacity of the treated tumors to grow locally in immuno-competent or in immuno-depressed hosts was retained and not significantly modified, the metastatic phenotype was eliminated when the trea...

journal_title：International journal of cancer

authors： Garbisa S,Onisto M,Peron A,Perissin L,Rapozzi V,Zorzet S,Giraldi T

更新日期：1997-09-17 00:00:00

abstract：:We reported that tumor endothelial cells (TECs) differ from normal endothelial cells (NECs) in many aspects, such as gene expression profiles. Although CXCR7 is reportedly highly expressed in blood vessels of several tumors, its function in TECs is still unknown. To investigate this role, we isolated TECs from mouse t...

journal_title：International journal of cancer

authors： Yamada K,Maishi N,Akiyama K,Towfik Alam M,Ohga N,Kawamoto T,Shindoh M,Takahashi N,Kamiyama T,Hida Y,Taketomi A,Hida K

更新日期：2015-12-15 00:00:00

abstract：:We have used immunoprecipitation to test tumor biopsies and normal adult and fetal human tissues for p97, a tumor-associated protein. Five of nine melanoma biopsies contained p97 in low to very high levels. Three of seven non-melanoma tumors contained p97, but in smaller amounts. No p97 was detected in any of the norm...

journal_title：International journal of cancer

authors： Woodbury RG,Brown JP,Loop SM,Hellström KE,Hellström I

更新日期：1981-02-15 00:00:00

abstract：:Posttransplant lymphoproliferative disorder (PTLD) is a common and life-threatening complication of immunosuppression used to prevent rejection of solid organ and bone marrow transplants. There is no standardized treatment algorithm, but numerous management strategies are available. We describe a patient who developed...

journal_title：International journal of cancer

authors： Koffman BH,Kennedy AS,Heyman M,Colonna J,Howell C

更新日期：2000-04-20 00:00:00

abstract：:Cancer awareness public campaigns aim to shorten the interval between symptom onset and presentation to a doctor (the 'patient interval'). Appreciating variation in promptness of presentation can help to better target awareness campaigns. We explored variation in patient intervals recorded in consultations with genera...

journal_title：International journal of cancer

authors： Keeble S,Abel GA,Saunders CL,McPhail S,Walter FM,Neal RD,Rubin GP,Lyratzopoulos G

更新日期：2014-09-01 00:00:00

abstract：:There is limited information present to explain temporal improvements in colon cancer survival. This nationwide study investigates the temporal changes in survival over a 35-year period (1970-2004) in Iceland and uses incidence, mortality, surgery rate, stage distribution, lymph node yield, tumor location and histolog...

journal_title：International journal of cancer

authors： Snaebjornsson P,Jonasson L,Olafsdottir EJ,van Grieken NCT,Moller PH,Theodors A,Jonsson T,Meijer GA,Jonasson JG

更新日期：2017-08-01 00:00:00

abstract：:The human HBL-100 cell line harbours SV40 DNA integrated in tandem at a unique site. The SV40 T-antigen expressed in these cells is defective in a function essential to the replication of the viral genome. The integrated SV40 sequences were molecularly cloned in a bacteriophage, and a subclone (plasmid pSVHBI) contain...

journal_title：International journal of cancer

authors： Saint-Ruf C,Nardeux P,Cebrian J,Lacasa M,Lavialle C,Cassingena R

更新日期：1989-08-15 00:00:00

abstract：:A hospital-based case-control study of renal-cell carcinoma was conducted in France from 1987 to 1991. A total of 196 histologically confirmed cases (138 males and 58 females) and 347 controls (235 males and 112 females), matched for sex, age at interview, hospital and interviewer, were included. The risk of renal-cel...

journal_title：International journal of cancer

authors： Benhamou S,Lenfant MH,Ory-Paoletti C,Flamant R

更新日期：1993-08-19 00:00:00

abstract：:In a cohort of 11,663 participants in a breast-cancer screening program, height, weight, waist circumference and hip circumference were measured, and information about menstrual and reproductive history was obtained by questionnaire. After exclusion of 83 women with unclear menopausal status, the subjects were divided...

journal_title：International journal of cancer

authors： Kaaks R,Van Noord PA,Den Tonkelaar I,Peeters PH,Riboli E,Grobbee DE

更新日期：1998-05-29 00:00:00

abstract：:We previously determined that human papillomavirus (HPV) virus-like particles (VLPs) and pseudovirions (PsV) did not, respectively, bind to or infect intact epithelium of the cervicovaginal tract. However, they strongly bound heparan sulfate proteoglycans (HSPG) on the basement membrane of disrupted epithelium and inf...

journal_title：International journal of cancer

authors： Kines RC,Cerio RJ,Roberts JN,Thompson CD,de Los Pinos E,Lowy DR,Schiller JT

更新日期：2016-02-15 00:00:00

abstract：:The CpG island methylator phenotype (CIMP) with widespread promoter CpG island methylation is a phenotype in colorectal cancer, associated with microsatellite instability (MSI) and BRAF mutation. Genome-wide hypomethylation may also play an important role in genomic instability. However, the relation between global DN...

journal_title：International journal of cancer

authors： Ogino S,Kawasaki T,Nosho K,Ohnishi M,Suemoto Y,Kirkner GJ,Fuchs CS

更新日期：2008-06-15 00:00:00

abstract：:Experimental and epidemiological evidence supports a role for sex steroid hormones in the pathogenesis of ovarian cancer. We investigated the association between ovarian cancer risk and pre-diagnostic blood concentrations of testosterone, androstenedione, DHEAS, estrone and SHBG. A case-control study nested within 3 c...

journal_title：International journal of cancer

authors： Lukanova A,Lundin E,Akhmedkhanov A,Micheli A,Rinaldi S,Zeleniuch-Jacquotte A,Lenner P,Muti P,Biessy C,Krogh V,Berrino F,Hallmans G,Riboli E,Kaaks R,Toniolo P

更新日期：2003-05-01 00:00:00

abstract：:The role of gastrin in the control of growth of renal G401 cells isolated from a human nephroblastoma (Wilms' tumour) was investigated. G401 cell growth was enhanced in the presence of exogenous gastrin. Addition of anti-gastrin antibodies to serum-free medium significantly inhibited the growth of G401 cells. G401 cel...

journal_title：International journal of cancer

authors： Blackmore M,Doherty E,Manning JE,Hirst BH

更新日期：1994-05-01 00:00:00

abstract：:Lysyl oxidase (LOX), a copper-dependent amine oxidase, has been implicated in tumor suppression and cell growth regulation. The chromosomal locus of LOX, 5q23, is affected by loss of heterozygosity (LOH) in colon cancer, suggesting that the LOX gene could be affected by LOH and consequently, loss or reduction of LOX f...

journal_title：International journal of cancer

authors： Csiszar K,Fong SF,Ujfalusi A,Krawetz SA,Salvati EP,Mackenzie JW,Boyd CD

更新日期：2002-02-10 00:00:00

abstract：:We compared and contrasted intracranial (i.c.) and subcutaneous (s.c.) heterotransplantation of small-cell carcinoma of the lung (SCCL) into athymic nude mice. Fresh human SCCL tumor specimens, tumor colonies grown in soft agarose and continuous cell lines were used. Tumors induced by the three types of specimens were...

journal_title：International journal of cancer

authors： Gazdar AF,Carney DN,Sims HL,Simmons A

更新日期：1981-12-01 00:00:00

abstract：:Ewing sarcoma (EWS) is the second most common and aggressive type of metastatic bone tumor in adolescents and young adults. There is unmet medical need to develop and test novel pharmacological targets and novel therapies to treat EWS. Here, we found that EWS expresses high levels of a p53 isoform, delta133p53. We fur...

journal_title：International journal of cancer

authors： Charan M,Dravid P,Cam M,Audino A,Gross AC,Arnold MA,Roberts RD,Cripe TP,Pertsemlidis A,Houghton PJ,Cam H

更新日期：2020-06-01 00:00:00

abstract：:General cell-mediated immune (CMI) functions in NPC patients were investigated by the in vivo Mantoux and in vitro lymphocyte response to PHA assays. Thirty-eight (50%) of 76 untreated NPC patients were hyporesponsive in the Mantoux assay compared to 27 (25%) of 110 control patients. Forty-three (65.2%) of 66 untreate...

journal_title：International journal of cancer

authors： Chan SH,Chew TS,Goh EH,Simons MJ,Shanmugaratnam K

更新日期：1976-08-15 00:00:00

abstract：:We transduced a human gastric carcinoma cell line, HR, with the interleukin 2 (IL-2) gene. Stable HR transfectants secreted nanogram quantities of biologically active IL-2 and had significantly increased expression of IL-2 mRNA relative to that in parental cells. Expression of intracellular IL-2 protein was not quanti...

journal_title：International journal of cancer

authors： Nagashima S,Kashii Y,Reichert TE,Suminami Y,Suzuki T,Whiteside TL

更新日期：1997-07-03 00:00:00

abstract：:Human papillomavirus-induced cervical carcinomas often show impaired expression of MHC class I molecules resulting in the inability of tumor cells to directly present viral peptides to cytotoxic T lymphocytes. Loss of MHC class I expression combined with the expression of activating NK cell receptor ligands renders tu...

journal_title：International journal of cancer

authors： Textor S,Dürst M,Jansen L,Accardi R,Tommasino M,Trunk MJ,Porgador A,Watzl C,Gissmann L,Cerwenka A

更新日期：2008-11-15 00:00:00

abstract：:Human papilloma virus is a causative factor in the etiology of cervical cancer with HPV16 being the most prevalent genotype associated with it. Intratype variations in oncogenic E6/E7 and capsid L1 proteins of HPV 16 besides being of phylogenetic importance, are associated with risk of viral persistence and progressio...

journal_title：International journal of cancer

authors： Pillai MR,Hariharan R,Babu JM,Lakshmi S,Chiplunkar SV,Patkar M,Tongaonkar H,Dinshaw K,Jayshree RS,Reddy BK,Siddiqui M,Roychoudury S,Saha B,Abraham P,Gnanamony M,Peedicayil A,Subhashini J,Ram TS,Dey B,Sharma C,Jain

更新日期：2009-07-01 00:00:00

abstract：:It has been proposed that the timing of breast-cancer surgery in relation to menstrual phase has a prognostic impact on outcome. We carefully evaluated a combined 2-center series of 385 pre-menopausal women operated on for stage-I and stage-II breast cancer with a median follow-up of 5 years for a possible impact on o...

journal_title：International journal of cancer

authors： Gnant MF,Seifert M,Jakesz R,Adler A,Mittlboeck M,Sevelda P

更新日期：1992-11-11 00:00:00