Risk factors for renal-cell carcinoma in a French case-control study.

abstract：:Pesticide exposure has been associated with non-Hodgkin lymphoma (NHL) risk in a number of studies, and two recent studies suggest that the increased risk may be confined to those with a history of asthma. We examined the interaction between occupational pesticide exposure and atopy on risk of NHL in an Australian pop...

journal_title：International journal of cancer

authors： Vajdic CM,Fritschi L,Grulich AE,Kaldor JM,Benke G,Kricker A,Hughes AM,Turner JJ,Milliken S,Goumas C,Armstrong BK

更新日期：2007-05-15 00:00:00

abstract：:In addition to antiviral effects, Type I interferons (IFN) have potent antiproliferative and immunomodulatory activities. Because of these properties IFNs have been evaluated as therapeutics for the treatment of a number of human diseases, including cancer. Currently, IFNs have been shown to be efficacious for the tre...

journal_title：International journal of cancer

authors： Wagner TC,Velichko S,Chesney SK,Biroc S,Harde D,Vogel D,Croze E

更新日期：2004-08-10 00:00:00

abstract：:The relationship between renal-cell cancer (RCC) and occupation was investigated in an international multicenter population-based case-control study. Study centers in Australia, Denmark, Germany, Sweden and the United States interviewed 1732 incident RCC cases and 2309 controls. Significant associations were found wit...

journal_title：International journal of cancer

authors： Mandel JS,McLaughlin JK,Schlehofer B,Mellemgaard A,Helmert U,Lindblad P,McCredie M,Adami HO

更新日期：1995-05-29 00:00:00

abstract：:Human papillomavirus (HPV) infection is the pathogenesis of anogenital cancers and genital warts in both men and women, whereas there is a scarcity of large studies focused on HPV prevalence in different anogenital sites of both sexes in the same population. From May to July 2014, 2,309 men and 2,378 women aged 18-55 ...

journal_title：International journal of cancer

authors： Wei F,Li M,Wu X,Yin K,Lan J,Sheng W,Guo M,Huang S,Wang Y,Li Y,Li R,Su Y,Wu T,Zhang J,Xia N

更新日期：2018-03-15 00:00:00

abstract：:Use of dietary supplements is rising in countries where colorectal cancer is prevalent. We conducted a systematic literature review and meta-analyses of prospective cohort studies on dietary supplement use and colorectal cancer risk. We identified relevant studies in Medline, Embase and Cochrane up to January 2013. Or...

journal_title：International journal of cancer

authors： Heine-Bröring RC,Winkels RM,Renkema JM,Kragt L,van Orten-Luiten AC,Tigchelaar EF,Chan DS,Norat T,Kampman E

更新日期：2015-05-15 00:00:00

abstract：:A simple and rapid variant of in situ hybridization on tissue sections (histo-blotting) usable for detection of specific RNA distribution among tissues is proposed. Tissue sections prepared with a cryostatic microtome are placed on nitrocellulose and these "histo-blots" are hybridized with labelled DNA or RNA probes u...

journal_title：International journal of cancer

authors： Gudkov AV,Kashkin KN,Zaitsevskaya TE,Troyanovsky SM

更新日期：1989-12-15 00:00:00

abstract：:Oncogenic HPV types are the major cause of worldwide cervical cancer, but only a small proportion of infected women will develop high-grade cervical intraepithelial neoplasia or cancer (CIN2/3+). We performed a prospective study including 781 women with normal, atypical squamous cells of undetermined significance (ASC...

journal_title：International journal of cancer

authors： Dalstein V,Riethmuller D,Prétet JL,Le Bail Carval K,Sautière JL,Carbillet JP,Kantelip B,Schaal JP,Mougin C

更新日期：2003-09-01 00:00:00

abstract：:The correlation between tumorigenicity and cell-surface adhesiveness was investigated in eight mouse fibroblastoid cell lines. Four of the lines (Mc 11-Mc 15) were derived from mouse MC-induced fibrosarcomas, two were derivatives of L cells (A9, A9HT), and two (clone 3 and clone 7 H7F4) were obtained by fusion of A9HT...

journal_title：International journal of cancer

authors： Bubeník J,Perlmann P,Fenyö EM,Jandlová T,Suhajová E,Malkovský M

更新日期：1979-03-15 00:00:00

abstract：:T-cell responses have been reported to be impaired in cancer patients, and lymphocytes infiltrating human tumors (T-TIL) appear to be more affected than those in the peripheral blood. T-TIL display a poor proliferative response when compared to peripheral blood T (T-PBL) cells that show a strong response to all stimul...

journal_title：International journal of cancer

authors： Kudoh S,Stanley J,Edinger MG,Tubbs RR,Klein E,Bukowski RM,Finke JH

更新日期：1994-08-01 00:00:00

abstract：:Anticancer drugs docetaxel and vinorelbine suppress cell growth by altering microtubule assembly and activating the proapoptotic signal pathway. Vinorelbine and docetaxel have been approved for treating several advanced cancers. However, their efficacy in the management of advanced hormone-refractory prostate cancer r...

journal_title：International journal of cancer

authors： Zelivianski S,Spellman M,Kellerman M,Kakitelashvilli V,Zhou XW,Lugo E,Lee MS,Taylor R,Davis TL,Hauke R,Lin MF

更新日期：2003-11-10 00:00:00

abstract：:The epidermal growth factor receptor (EGFR) is frequently expressed in triple-negative breast cancer (TNBC) and is a marker of poor prognosis in this patient population. Because activating mutations in this kinase are very rare events in breast cancer, we screened breast tumor gene expression profiles to examine the d...

journal_title：International journal of cancer

authors： Giricz O,Calvo V,Peterson EA,Abouzeid CM,Kenny PA

更新日期：2013-12-01 00:00:00

abstract：:A series of 722 lung carcinomas, surgically resected and typed some years ago according to the 1967 WHO classification, was independently reviewed by 2 observers in order to test the reproducibility of histopathological typing when using the criteria of the 1981 WHO classification. Typing was fully agreed upon in 87% ...

journal_title：International journal of cancer

authors： Campobasso O,Andrion A,Ribotta M,Ronco G

更新日期：1993-01-21 00:00:00

abstract：:Azacytidine and decitabine are approved for treatment of acute myeloid leukemias and myelodysplastic syndromes. While clinical responses are attributed to epigenetic effects and induction of apoptosis in malignant cells, these azanucleosides also affect antitumor immune responses. NK cells as components of innate immu...

journal_title：International journal of cancer

authors： Schmiedel BJ,Arélin V,Gruenebach F,Krusch M,Schmidt SM,Salih HR

更新日期：2011-06-15 00:00:00

abstract：:Oxidative stress plays a role in the regulation of cancer cell metastasis which involves cell invasion and adhesion that could be supported by ADAM proteins through the activities of their metalloprotease and disintegrin domains. We hypothesized that oxidative stress could act through the induction of ADAM9 protein in...

journal_title：International journal of cancer

authors： Mongaret C,Alexandre J,Thomas-Schoemann A,Bermudez E,Chéreau C,Nicco C,Goldwasser F,Weill B,Batteux F,Lemare F

更新日期：2011-08-15 00:00:00

abstract：:Lethally X-irradiated LEW rats reconstituted with syngeneic bone marrow and given low-dose Cyclosporine A (CyA) for 5 weeks develop, after withdrawal of CyA, symptoms of disease resembling graft-vs.-host disease (GVHD) as seen after allogeneic bone-marrow transplantation. Symptoms of disease may include acute dermatit...

journal_title：International journal of cancer

authors： Wodzig KW,Beijleveld LJ,Damoiseaux JG,Arends JW,van Breda Vriesman PJ

更新日期：1997-07-29 00:00:00

abstract：:Diabetes is a risk factor for many cancers; chronic hyperglycemia is hypothesized to be, in part, explanatory. We evaluated the association between glycated hemoglobin, a time-integrated glycemia measure, and cancer incidence and mortality in nondiabetic and diabetic men and women. We conducted a prospective study of ...

journal_title：International journal of cancer

authors： Joshu CE,Prizment AE,Dluzniewski PJ,Menke A,Folsom AR,Coresh J,Yeh HC,Brancati FL,Platz EA,Selvin E

更新日期：2012-10-01 00:00:00

abstract：:Chloroethylene oxide and 2-chloroacetaldehyde, two possibly carcinogenic metabolities of vinyl chloride in mammals, caused a dose-dependent induction of 8-azaguanine- and ouabain-resistant mutants in Chinese hamster V79 cells in vitro. Up to one-hundred-fold higher concentrations of 2-chloroethanol or monochloroacetic...

journal_title：International journal of cancer

authors： Huberman E,Bartsch H,Sachs L

更新日期：1975-10-15 00:00:00

abstract：:The cystine/glutamate antiporter, system xc- , is essential for the efficient uptake of cystine into cells. Interest in the mechanisms of system xc- function soared with the recognition that system xc- presents the most upstream node of ferroptosis, a recently described form of regulated necrosis relevant for degenera...

journal_title：International journal of cancer

authors： Sato M,Onuma K,Domon M,Hasegawa S,Suzuki A,Kusumi R,Hino R,Kakihara N,Kanda Y,Osaki M,Hamada J,Bannai S,Feederle R,Buday K,Angeli JPF,Proneth B,Conrad M,Okada F,Sato H

更新日期：2020-12-01 00:00:00

abstract：:The predictive effect of circulating tumor DNA (ctDNA) in colorectal cancer (CRC) treatment is still highly discussed. The primary objective of our study was to investigate a possible prognostic/predictive value of ctDNA under regorafenib treatment. This prospective multicenter translational biomarker phase II pilot s...

journal_title：International journal of cancer

authors： Unseld M,Belic J,Pierer K,Zhou Q,Moser T,Bauer R,Piringer G,Gerger A,Siebenhüner A,Speicher M,Heitzer E,Prager GW

更新日期：2021-03-15 00:00:00

abstract：:This is a prospective study of lymphoid tissue showing benign reactive hyperplasia (18 lymph nodes and 2 tonsils), using cytogenetic analysis of cells stimulated with T- or B-cell mitogens. The reason for this study was the detection of an abnormal chromosomal population in cells from an enlarged lymph node excised fr...

journal_title：International journal of cancer

authors： Grace J,Hall BE,Lew M,Singh S,Pittman S,Palmer AA,Zbroja R,Wass J,Vincent PC

更新日期：1989-12-15 00:00:00

abstract：:The role of the mismatch repair (MMR) system in correcting base-base mismatches is well established; its involvement in the response to DNA double strand breaks, however, is less clear. We investigated the influence of the essential component of MMR, the hMLH1 protein, on the cellular response to DNA-double strand bre...

journal_title：International journal of cancer

authors： Bhonde MR,Hanski ML,Stehr J,Jebautzke B,Peiró-Jordán R,Fechner H,Yokoyama KK,Lin WC,Zeitz M,Hanski C

更新日期：2010-06-15 00:00:00

abstract：:Long-term survival rates for advanced ovarian cancer patients have not changed appreciably over the past four decades; therefore, development of new, effective treatment modalities remains a high priority. Tumor Treating Fields (TTFields), a clinically active anticancer modality utilize low-intensity, intermediate fre...

journal_title：International journal of cancer

authors： Voloshin T,Munster M,Blatt R,Shteingauz A,Roberts PC,Schmelz EM,Giladi M,Schneiderman RS,Zeevi E,Porat Y,Bomzon Z,Urman N,Itzhaki A,Cahal S,Kirson ED,Weinberg U,Palti Y

更新日期：2016-12-15 00:00:00

abstract：:Immunohistochemical and/or indirect immunofluorescence analysis with monoclonal antibody (MAb) H19 demonstrated the expression of protectin (CD59) in 54 surgically removed metastatic melanoma lesions and on 8 out of 12 melanoma cell lines. CD59 expression had a low degree of intra- and intertumor heterogeneity. SDS-PA...

journal_title：International journal of cancer

authors： Brasoveanu LI,Altomonte M,Gloghini A,Fonsatti E,Coral S,Gasparollo A,Montagner R,Cattarossi I,Simonelli C,Cattelan A

更新日期：1995-05-16 00:00:00

abstract：:Trends in incidence rates of cutaneous malignant melanoma in Western Australia from 1975-76 to 1980-1981 have been examined with reference to age, sex, body site, presence or absence of dermal invasion, tumour thickness, histological type, socioeconomic status and occupation. The incidence rates of all melanomas incre...

journal_title：International journal of cancer

authors： English DR,Heenan PJ,Holman CD,Armstrong BK,Blackwell JB,Kelsall GR,Matz LR,Singh A,ten Seldam RE

更新日期：1986-02-15 00:00:00

abstract：:Membrane-bound complement regulatory proteins provide tumor cells with protection from antibody and complement in vitro. However, complement regulators are widely expressed on normal tissue, and inhibiting the function of complement regulatory proteins on tumor cells in vivo has not been investigated due to the absenc...

journal_title：International journal of cancer

authors： Imai M,Ohta R,Okada N,Tomlinson S

更新日期：2004-07-20 00:00:00

abstract：:Obesity is considered a chronic inflammatory state characterized by continued secretion of adipokines and cytokines. Experimental and epidemiological evidence indicates that circulating adipokines may be associated with the development of obesity-related cancers, but it is unclear if these associations are causal or c...

journal_title：International journal of cancer

authors： Dimou NL,Papadimitriou N,Mariosa D,Johansson M,Brennan P,Peters U,Chanock SJ,Purdue M,Bishop DT,Gago-Dominquez M,Giles GG,Moreno V,Platz EA,Tangen CM,Wolk A,Zheng W,Wu X,Campbell PT,Giovannucci E,Lin Y,CCFR, Endom

更新日期：2020-10-10 00:00:00

abstract：:I-compounds are bulky indigenous DNA adducts that can be detected by (32)P-postlabeling. A subgroup, termed type II I-compounds, represents DNA lesions induced by oxidative stress. Several major type II I-compounds have been identified as dinucleotides containing 3'-terminal 8,5'-cyclo-2'-deoxyadenosine (cA). Levels o...

journal_title：International journal of cancer

authors： Zhou GD,Randerath K,Donnelly KC,Jaiswal AK

更新日期：2004-12-10 00:00:00

abstract：:The variable domain of functional heavy chain antibodies (VHH) devoid of light chains, found in camels, constitute the smallest intact antigen-binding domain fragment. Two camel single-domain fragments, cAb-Lys2 and cAb-Lys3, recognizing an overlapping epitope of lysozyme with a dissociation constant of 2 nM and 65 nM...

journal_title：International journal of cancer

authors： Cortez-Retamozo V,Lauwereys M,Hassanzadeh Gh G,Gobert M,Conrath K,Muyldermans S,De Baetselier P,Revets H

更新日期：2002-03-20 00:00:00

abstract：:Prostate-specific antigen (PSA) has been characterized as a specific prostate marker, although recent studies have suggested the existence of PSA of nonprostatic sources. We have assessed the presence of PSA by an ultrasensitive assay in 276 serum and nonserum samples from women. Our data show the presence of PSA in 9...

journal_title：International journal of cancer

authors： Filella X,Molina R,Alcover J,Carretero P,Ballesta AM

更新日期：1996-11-15 00:00:00

abstract：:Gene silencing by DNA hypermethylation of CpG islands is a well-characterized phenomenon in cancer. The effect of hypomethylation in particular of non-CpG island genes is much less well described. By genome-wide screening, we identified 105 genes in microsatellite stable (MSS) colorectal adenocarcinomas with an invers...

journal_title：International journal of cancer

authors： Øster B,Linnet L,Christensen LL,Thorsen K,Ongen H,Dermitzakis ET,Sandoval J,Moran S,Esteller M,Hansen TF,Lamy P,COLOFOL steering group.,Laurberg S,Ørntoft TF,Andersen CL

更新日期：2013-05-15 00:00:00