Inhibitory effects of olive oil phenolics on invasion in human colon adenocarcinoma cells in vitro.

abstract：:The cystine/glutamate antiporter, system xc- , is essential for the efficient uptake of cystine into cells. Interest in the mechanisms of system xc- function soared with the recognition that system xc- presents the most upstream node of ferroptosis, a recently described form of regulated necrosis relevant for degenera...

journal_title：International journal of cancer

authors： Sato M,Onuma K,Domon M,Hasegawa S,Suzuki A,Kusumi R,Hino R,Kakihara N,Kanda Y,Osaki M,Hamada J,Bannai S,Feederle R,Buday K,Angeli JPF,Proneth B,Conrad M,Okada F,Sato H

更新日期：2020-12-01 00:00:00

abstract：:Effects of 12-O-tetradecanoyl phorbol 13-acetate (TPA) and the hepatic peroxisome proliferators (HPPs) clofibrate, methyl clofenapate (MCP), di(2-ethylhexyl)phthalate (DEHP) and mono(2-ethylhexyl)phthalate (MEHP) were studied in 2 gap junctional intercellular communication (GJIC) systems, metabolic cooperation in V79 ...

journal_title：International journal of cancer

authors： Cruciani V,Mikalsen SO,Vasseur P,Sanner T

更新日期：1997-10-09 00:00:00

abstract：:The causative role of human papillomaviruses (HPV) and HPV16 variants has been extensively studied in uterine cervix dysplastic lesions and invasive carcinoma; few such studies, however, have been performed in penile tumors. We have investigated HPV genotype and HPV16 variant distribution on 41 penile cancer biopsies ...

journal_title：International journal of cancer

authors： Tornesello ML,Duraturo ML,Losito S,Botti G,Pilotti S,Stefanon B,De Palo G,Gallo A,Buonaguro L,Buonaguro FM

更新日期：2008-01-01 00:00:00

abstract：:We conducted a retrospective cohort study to investigate the colorectal cancer (CRC) incidence and mortality prevention achievable in clinical practice with an optimized colonoscopy protocol targeting near-complete polyp clearance. The protocol consisted of: (i) telephonic reinforcement of bowel preparation instructio...

journal_title：International journal of cancer

authors： Xirasagar S,Li YJ,Hurley TG,Tsai MH,Hardin JW,Hurley DM,Hebert JR,de Groen PC

更新日期：2015-03-15 00:00:00

abstract：:Artemisia asiatica Nakai has been used in traditional Asian medicine for the treatment of inflammatory and other disorders. Previous studies have revealed that the formulated ethanol extract (DA-9601) of A. asiatica has pronounced antioxidative and antiinflammatory activities and exhibits cytoprotective effects agains...

journal_title：International journal of cancer

authors： Seo HJ,Park KK,Han SS,Chung WY,Son MW,Kim WB,Surh YJ

更新日期：2002-08-01 00:00:00

abstract：:Production of interleukin-6 (IL-6) by human pancreatic carcinoma cells inversely correlates with potentials for blood-borne metastasis to the liver in nude mice. IL-6 cDNA was transfected to PCI-43, one of our cultured pancreatic carcinoma cell lines that does not produce IL-6 and generates numerous metastases to the ...

journal_title：International journal of cancer

authors： Saito K,Ishikura H,Kishimoto T,Kawarada Y,Yano T,Takahashi T,Kato H,Yoshiki T

更新日期：1998-01-19 00:00:00

abstract：:Infection with a simian retrovirus (STLV-I) closely related to human T-lymphotropic virus type I (HTLV-I) was investigated in non-human primates living in their native countries in Africa and Asia. Serum antibodies cross-reacting with HTLV-I antigens were detected in 85 of 567 non-human primates of 30 species. Seropos...

journal_title：International journal of cancer

authors： Ishikawa K,Fukasawa M,Tsujimoto H,Else JG,Isahakia M,Ubhi NK,Ishida T,Takenaka O,Kawamoto Y,Shotake T

更新日期：1987-08-15 00:00:00

abstract：:The light microscopic distinction between complex atypical hyperplasia (CAH) and invasive endometrioid carcinoma (UEC) on endometrial sampling is problematic and often has significant clinical implications. Using mouse models of endometrial tumorigenesis based on two of the most common molecular alterations found in p...

journal_title：International journal of cancer

authors： Wang H,Joshi A,Iaconis L,Solomon GJ,Xiang Z,Verhage HG,Douglas W,Ronnett BM,Ellenson LH

更新日期：2009-03-15 00:00:00

abstract：:Galunisertib (LY2157299), a promising small-molecule inhibitor of the transforming growth factor-beta (TGF-β) receptor, is currently in mono- and combination therapy trials for various cancers including glioblastoma, hepatocellular carcinoma and breast cancer. Using genetically modified mouse models, we investigated t...

journal_title：International journal of cancer

authors： Li W,Tibben M,Wang Y,Lebre MC,Rosing H,Beijnen JH,Schinkel AH

更新日期：2020-03-15 00:00:00

abstract：:Osteosarcomas are primary bone tumors of osteoblastic origin that mostly affect adolescent patients. These tumors are highly aggressive and metastatic. Previous reports indicate that gain of function of a key osteoblastic differentiation factor, Runx2, leads to growth inhibition in osteosarcoma. We have previously est...

journal_title：International journal of cancer

authors： Shapovalov Y,Benavidez D,Zuch D,Eliseev RA

更新日期：2010-07-01 00:00:00

abstract：:The relationship between occupation and exposure to several occupational agents and Hodgkin's disease (HD) was investigated in a case-control study of 152 cases and 613 controls with acute diseases admitted to all hospitals in Pordenone province, north-east Italy. Among cases, there was a significant excess of individ...

journal_title：International journal of cancer

authors： Franceschi S,Serraino D,La Vecchia C,Bidoli E,Tirelli U

更新日期：1991-07-30 00:00:00

abstract：:We compared and contrasted intracranial (i.c.) and subcutaneous (s.c.) heterotransplantation of small-cell carcinoma of the lung (SCCL) into athymic nude mice. Fresh human SCCL tumor specimens, tumor colonies grown in soft agarose and continuous cell lines were used. Tumors induced by the three types of specimens were...

journal_title：International journal of cancer

authors： Gazdar AF,Carney DN,Sims HL,Simmons A

更新日期：1981-12-01 00:00:00

abstract：:Biopsies were obtained from 12 patients suspected of having nasopharyngeal carcinoma (NPC). A portion of the tissue was submitted for histopathology and another for Western blotting using a murine monoclonal antibody (MAb), MA6. Touch smears of the tissues were also prepared immediately prior to extraction and Western...

journal_title：International journal of cancer

authors： Yip TC,Chan KH,Choy D,Chan CW,Ng MH

更新日期：1987-04-15 00:00:00

abstract：:Several lines of evidence have demonstrated that IFNs could be relevant in the treatment of certain neoplastic diseases such as carcinomas. In particular, IFN-alpha, in addition to the anti-proliferative and cytostatic effects, was demonstrated to be capable of inducing cell death by apoptosis both in vivo and in vitr...

journal_title：International journal of cancer

authors： Matarrese P,Giandomenico V,Fiorucci G,Rivabene R,Straface E,Romeo G,Affabris E,Malorni W

更新日期：1998-05-18 00:00:00

abstract：:Human papillomavirus (HPV) causes oropharyngeal squamous cell carcinoma (OPSCC), although strongly divergent results have been reported regarding the prevalence of HPV16 in different countries, whether this represents important differences in etiology remains unclear. Applying rigorous protocols for sample processing,...

journal_title：International journal of cancer

authors： Anantharaman D,Abedi-Ardekani B,Beachler DC,Gheit T,Olshan AF,Wisniewski K,Wunsch-Filho V,Toporcov TN,Tajara EH,Levi JE,Moyses RA,Boccia S,Cadoni G,Rindi G,Ahrens W,Merletti F,Conway DI,Wright S,Carreira C,Renard H

更新日期：2017-05-01 00:00:00

abstract：:Human mammary tumours which are histologically well differentiated are more likely to synthesize receptors for estrogen (ER) and progesterone (PR) and to respond to systemic endocrine therapy. The aim of this study was to explore the relationship between differentiation, receptors and endocrine responsiveness in more ...

journal_title：International journal of cancer

authors： Baildam AD,Howell A,Barnes DM,Redford J,Healy K,Swindell R,Sellwood RA

更新日期：1988-08-15 00:00:00

abstract：:Dietary information from a case-control study of pancreatic cancer conducted in Metropolitan Toronto between 1983 and 1986 is reported. A total of 249 cases and 505 population-based controls completed quantitative diet histories from which total caloric intake and the intake of a number of nutrients were estimated. A ...

journal_title：International journal of cancer

authors： Howe GR,Jain M,Miller AB

更新日期：1990-04-15 00:00:00

abstract：:In order to clarify the frequency of p16 gene inactivation and its relationship with Rb expression, immunohistochemical analysis of p16 and Rb proteins was carried out on 82 paraffin-embedded sections of primary non-small cell lung cancers (NSCLCs). From immunohistochemical results, abnormal p16 expression was observe...

journal_title：International journal of cancer

authors： Kashiwabara K,Oyama T,Sano T,Fukuda T,Nakajima T

更新日期：1998-06-19 00:00:00

abstract：:Antioxidants, primarily from fruits and vegetables, have been hypothesized to protect against non-Hodgkin lymphoma (NHL). The oxygen radical absorbance capacity (ORAC) assay, which measures total antioxidant capacity of individual foods and accounts for synergism, can be estimated using a food-frequency questionnaire ...

journal_title：International journal of cancer

authors： Holtan SG,O'Connor HM,Fredericksen ZS,Liebow M,Thompson CA,Macon WR,Micallef IN,Wang AH,Slager SL,Habermann TM,Call TG,Cerhan JR

更新日期：2012-09-01 00:00:00

abstract：:In normal somatic cells, the methylation pattern of DNA is stably maintained by DNA (cytosine-5-)-methyltransferase (DNA methyltransferase). Increased expression of DNA methyltransferase has been detected in many types of human cancer and has been thought to play an important role in tumorigenesis. In our study, we de...

journal_title：International journal of cancer

authors： Chen B,Liu X,Savell VH,Dilday BR,Johnson MW,Jenkins JJ,Parham DM

更新日期：1999-09-24 00:00:00

abstract：:An immunopotentiating factor associated with spleen cells of C57BL/6J mice bearing the 3LL tumor is described. Supernatants of cultured spleen cells from tumor-bearing mice (TBM) augmented the generation of both 19S and 7S antibody-producing cells, when injected with sheep erythrocytes into syngeneic C57BL/6J mice. Th...

journal_title：International journal of cancer

authors： Isakov N,Segal S,Hollander N,Feldman M

更新日期：1978-10-15 00:00:00

abstract：:Osteosarcoma incidence rates in the United States peak in adolescence and in the elderly. The international patterns of osteosarcoma incidence in children have been described, whereas those for young, middle age or elderly adults have not. Using the Cancer Incidence in Five Continents, International Agency for Cancer ...

journal_title：International journal of cancer

authors： Mirabello L,Troisi RJ,Savage SA

更新日期：2009-07-01 00:00:00

abstract：:A case-control study of 374 patients with primary epithelial cancers of the oral cavity, oro- and hypopharynx, and larynx is reported, the controls being patients with selected other cancers, matched for age and sex. Of all eligible patients, 93% were interviewed. Increased risks were seen with alcohol consumption and...

journal_title：International journal of cancer

authors： Elwood JM,Pearson JC,Skippen DH,Jackson SM

更新日期：1984-11-15 00:00:00

abstract：:The relative proportions of T, B and T gamma suppressor cells were determined sequentially in peripheral blood of melanoma patients before and after surgery. Concanavalin A (Con A)-induced suppression against lymphocyte mitogenesis of melanoma patients and age matched controls was measured concurrently. The mean perce...

journal_title：International journal of cancer

authors： Werkmeister J,Phillips G,McCarthy W,Hersey P

更新日期：1981-07-15 00:00:00

abstract：:Phenotypic differences among cancers with the same origin may be associated with chemotherapy response. CHFR silencing associated with DNA methylation has been suggested to be predictive of taxane sensitivity in diverse tumor types. However, the use of microsatellite instability (MSI:unstable-MSS:stable) as a predicti...

journal_title：International journal of cancer

authors： Pelosof L,Yerram SR,Ahuja N,Delmas A,Danilova L,Herman JG,Azad NS

更新日期：2014-02-01 00:00:00

abstract：:The possibility that women, who receive breast implants for cosmetic purposes, have increased long-term risks of developing cancer continues to be debated. The objective of our study was to prospectively examine cancer incidence among women who received breast implants. A cohort was assembled of 24,558 women, 18 years...

journal_title：International journal of cancer

authors： Brisson J,Holowaty EJ,Villeneuve PJ,Xie L,Ugnat AM,Latulippe L,Mao Y

更新日期：2006-06-01 00:00:00

abstract：:The transcription factor PAX3 is expressed during early embryogenesis and in multiple cancer types, including embryonal rhabdomyosarcoma (ERMS), Ewing sarcoma (ES) and malignant melanoma (MEL), suggesting that it could function as a general tumor associated antigen. Major histocompatibility complex (MHC) peptide bindi...

journal_title：International journal of cancer

authors： Rodeberg DA,Nuss RA,Elsawa SF,Erskine CL,Celis E

更新日期：2006-07-01 00:00:00

abstract：:Monoclonal antibody 38.13 was raised against the Burkitt lymphoma cell line Daudi and has been previously shown to recognize a globotriaosylceramide (Pk) determinant expressed selectively on Burkitt and a few other B-cell lymphomas. We report here that 38.13 binds to a subset of normal B lymphocytes in germinal centre...

journal_title：International journal of cancer

authors： Murray LJ,Habeshaw JA,Wiels J,Greaves MF

更新日期：1985-11-15 00:00:00

abstract：:Glioblastoma multiforme (GBM) is the most lethal brain malignancy which involves multi-gene abnormality. Unfortunately, effective therapy against GBM remains lacking. Previously, we found that NRP-1 and its downstream NRP-1/GIPC1 pathway played an important role in GBM. In our study, we further investigated the upstre...

journal_title：International journal of cancer

authors： Zhang G,Chen L,Khan AA,Li B,Gu B,Lin F,Su X,Yan J

更新日期：2018-08-01 00:00:00

abstract：:ECOG 1696 was a Phase II multi-center trial testing vaccination with melanoma peptides, gp100, MART-1 and tyrosinase delivered alone, with GM-CSF, IFN-α2b or both cytokines to HLA-A2(+) patients with metastatic melanoma. Here, the frequency of circulating CD8(+) tetramer(+) (tet(+) ) T cells and maturation stages of...

journal_title：International journal of cancer

authors： Schaefer C,Butterfield LH,Lee S,Kim GG,Visus C,Albers A,Kirkwood JM,Whiteside TL

更新日期：2012-08-15 00:00:00