Humoral antibody response against Bacteroides gingivalis-specific antigen recognized by monoclonal antibody in adult periodontal patients.

abstract：:Immunoglobulin G (IgG) antibodies against hepatitis B surface antigen were found to be restricted to subclasses IgG1 and IgG3 in serum samples of 17 individuals. Quantitative determinations showed that in 10 samples the minor serum subclass IgG3 contained more antibodies than the predominant subclass IgG1. Ranges of c...

journal_title：Infection and immunity

authors： Morell A,Roth-Wicky B,Skvaril F

更新日期：1983-02-01 00:00:00

abstract：:Male ICR Swiss mice (2 to 3 months old) were fed Candida albicans in their drinking water for 3 days, followed by no treatment, antibiotics in their drinking water (daily), or immunosuppressants given by intraperitoneal injection (two to three times weekly) over a 3- to 4-week period. The organs of animals were proces...

journal_title：Infection and immunity

authors： Ekenna O,Sherertz RJ

更新日期：1987-07-01 00:00:00

abstract：:Although serum amyloid P component (SAP) is known to bind many ligands, its biological function is not yet clear. Recently, it was demonstrated that SAP binds to lipopolysaccharide (LPS). In the present study, SAP was shown to bind to gram-negative bacteria expressing short types of LPS or lipo-oligosaccharide (LOS), ...

journal_title：Infection and immunity

authors： de Haas CJ,van Leeuwen EM,van Bommel T,Verhoef J,van Kessel KP,van Strijp JA

更新日期：2000-04-01 00:00:00

abstract：:The protozoan parasite Entamoeba histolytica causes amebic dysentery and amebic liver abscess, diseases associated with significant morbidity and mortality worldwide. E. histolytica infection appears to involve the initial attachment of amebic trophozoites to intestinal epithelial cells, followed by lysis of these cel...

journal_title：Infection and immunity

authors： Seydel KB,Li E,Swanson PE,Stanley SL Jr

更新日期：1997-05-01 00:00:00

abstract：:The possibility that soluble products of Schistosoma mansoni eggs might participate in the pathogenesis of hepatic fibrosis in schistosomiasis was investigated. Both crude saline extracts of eggs (soluble egg antigen [SEA]) and a partially purified SEA fraction contained activity which stimulated guinea pig and human ...

journal_title：Infection and immunity

authors： Wyler DJ,Tracy JW

更新日期：1982-10-01 00:00:00

abstract：:The pac gene of the serotype c strain Streptococcus mutans MT8148 encodes a cell surface protein antigen (PAc) of approximate 190 kilodaltons. The serotype c strain S. mutans GS-5 does not produce the 190-kilodalton PAc but produces a lower-molecular-weight protein that reacts with anti-PAc serum. The SphI-BamHI fragm...

journal_title：Infection and immunity

authors： Koga T,Okahashi N,Takahashi I,Kanamoto T,Asakawa H,Iwaki M

更新日期：1990-02-01 00:00:00

abstract：:Eperythrozoon coccoides is a common blood parasite of rodents and the etiological agent of a chronic infection present in many mouse colonies. After primary infection, mice develop a parasitemia and anemia followed by a chronic, latent infection. During the acute phase of infection, mice manifest a striking suppressio...

journal_title：Infection and immunity

authors： Glasgow LA,Odugbemi T,Dwyer P,Ritterson AL

更新日期：1971-10-01 00:00:00

abstract：:Cutaneous lesions of the human sexually transmitted genital ulcer disease chancroid are characterized by the presence of intraepidermal pustules, keratinocyte cytopathology, and epidermal and dermal erosion. These lesions are replete with neutrophils, macrophages, and CD4(+) T cells and contain very low numbers of cel...

journal_title：Infection and immunity

authors： San Mateo LR,Toffer KL,Orndorff PE,Kawula TH

更新日期：1999-09-01 00:00:00

abstract：:The cytolethal distending toxin (Cdt) of Actinobacillus actinomycetemcomitans is an atypical A-B-type toxin consisting of a heterotrimer composed of the cdtA, cdtB, and cdtC gene products. The CdtA and CdtC subunits form two heterogeneous ricin-like lectin domains which bind the holotoxin to the target cell. Point mut...

journal_title：Infection and immunity

authors： Cao L,Volgina A,Korostoff J,DiRienzo JM

更新日期：2006-09-01 00:00:00

abstract：:As an opportunistic bacterial pathogen, Pseudomonas aeruginosa mainly affects immunocompromised individuals as well as patients with cystic fibrosis. In a previous study, we showed that ExoS of P. aeruginosa, when injected into host cells through a type III secretion apparatus, functions as an effector molecule to tri...

journal_title：Infection and immunity

authors： Jia J,Alaoui-El-Azher M,Chow M,Chambers TC,Baker H,Jin S

更新日期：2003-06-01 00:00:00

abstract：:Infection with the protozoan parasite Toxoplasma gondii is transmitted to humans from infected animals by tissue cysts and oocysts excreted by cats. Immunization with inactivated parasites or recombinant proteins has at best shown partial protection. We constructed a plasmid expressing the SAG1 surface antigen of T. g...

journal_title：Infection and immunity

authors： Nielsen HV,Lauemøller SL,Christiansen L,Buus S,Fomsgaard A,Petersen E

更新日期：1999-12-01 00:00:00

abstract：:Passive transfer of antibody may be useful for preexposure prophylaxis against biological agents used as weapons of terror, such as Bacillus anthracis. Studies were performed to evaluate the ability of anthrax antiprotective antigen (anti-PA) and antilethal factor (anti-LF) neutralizing monoclonal antibodies (mAbs) to...

journal_title：Infection and immunity

authors： Staats HF,Alam SM,Scearce RM,Kirwan SM,Zhang JX,Gwinn WM,Haynes BF

更新日期：2007-11-01 00:00:00

abstract：:Haemophilus ducreyi, the causative agent of chancroid, produces a lipooligosaccharide (LOS) which terminates in N-acetyllactosamine. This glycoform can be further extended by the addition of a single sialic acid residue to the terminal galactose moiety. H. ducreyi does not synthesize sialic acid, which must be acquire...

journal_title：Infection and immunity

authors： Post DM,Mungur R,Gibson BW,Munson RS Jr

更新日期：2005-10-01 00:00:00

abstract：:Antibody to Pseudomonas aeruginosa exotoxin was detected in human sera by using a cytotoxicity-neutralization assay. Serum antitoxin was present in high titer in all 14 patients who recovered from serious pseudomonas infections (log2 of 50% neutralization titer, mean +/- standard deviation = 6.0 +/- 1.2). In contrast,...

journal_title：Infection and immunity

authors： Pollack M,Callahan LT 3rd,Taylor NS

更新日期：1976-10-01 00:00:00

abstract：:Nontypeable Haemophilus influenzae (NTHi) is a common cause of otitis media and respiratory tract infections. Outer membrane proteins (OMP) and lipooligosaccharide (LOS) are major surface antigens of NTHi and potential vaccine candidates. De-O-acylated LOS (dLOS) or oligosaccharide (OS) was coupled to total OMP to for...

journal_title：Infection and immunity

authors： Wu TH,Gu XX

更新日期：1999-10-01 00:00:00

abstract：:Helicobacter mustelae, like Helicobacter pylori, possesses two flagellin proteins, FlaA and FlaB. Isogenic mutant strains of H. mustelae have been constructed by disruption of the flaA or flaB gene with a kanamycin resistance cassette or by introduction of both a kanamycin and a chloramphenicol resistance gene to prod...

journal_title：Infection and immunity

authors： Andrutis KA,Fox JG,Schauer DB,Marini RP,Li X,Yan L,Josenhans C,Suerbaum S

更新日期：1997-05-01 00:00:00

abstract：:Chronic Helicobacter pylori infection is associated with mucosal inflammation. The aim of the present study was to assess human neutrophil and monocyte activation by H. pylori strains obtained from patients with different clinical presentations. Bacterial sonicates from 12 strains were used to stimulate phagocyte upre...

journal_title：Infection and immunity

authors： Hansen PS,Go MF,Varming K,Andersen LP,Genta RM,Graham DY,Nielsen H

更新日期：1999-06-01 00:00:00

abstract：:The outer membrane of pathogenic Leptospira species grown in culture media contains lipopolysaccharide (LPS), a porin (OmpL1), and several lipoproteins, including LipL36 and LipL41. The purpose of this study was to characterize the expression and distribution of these outer membrane antigens during renal infection. Ha...

journal_title：Infection and immunity

authors： Barnett JK,Barnett D,Bolin CA,Summers TA,Wagar EA,Cheville NF,Hartskeerl RA,Haake DA

更新日期：1999-02-01 00:00:00

abstract：:The effects of 1,25-dihydroxy vitamin D3 and gamma interferon on the phenotypic changes associated with monocyte maturation in vitro were investigated. Human monocytes separated from peripheral blood mononuclear cell populations by adherence to plastic were cultured for 7 days on glass. Immunocytological analysis was ...

journal_title：Infection and immunity

authors： Poulter LW,Rook GA,Steele J,Condez A

更新日期：1987-09-01 00:00:00

abstract：:Previous reports from our laboratory have shown that 7 days after infection of C3HeB/FeJ mice with an attenuated strain of Salmonella typhimurium, there is profound suppression of responses to B- and T-cell mitogens and suppression of the capacity of spleen cells to mount a primary, in vitro plaque-forming-cell (PFC) ...

journal_title：Infection and immunity

authors： Huang D,Schwacha MG,Eisenstein TK

更新日期：1996-09-01 00:00:00

abstract：:The purpose of our study was to characterize the properties of the interaction of pertussis toxin with human polymorphonuclear leukocytes for the modulation of leukotriene generation and metabolism. The cells were stimulated with either the Ca ionophore A23187, opsonized zymosan, or the bacterial peptide formyl-methio...

journal_title：Infection and immunity

authors： Hensler T,Raulf M,Megret F,Alouf JE,König W

更新日期：1989-10-01 00:00:00

abstract：:With a purified beta-propiolactone-inactivated rabies virus, a significant increase in footpad swelling was elicited in normal or in BCG-pretreated mice after immunization with varying doses of rabies vaccine. These footpad reactions were shown to peak at 24 h and to be associated with an infiltration of newly formed ...

journal_title：Infection and immunity

authors： Lagrange PH,Tsiang H,Hurtrel B,Ravisse P

更新日期：1978-09-01 00:00:00

abstract：:Fimbriae are colonization factors of the human pathogen Haemophilus influenzae in that they mediate bacterial adherence to human eukaryotic cells. The contribution of the major (HifA) and putative minor (HifD and HifE) subunits of H. influenzae fimbriae to fimbria-specific adherence was studied by using mutants that w...

journal_title：Infection and immunity

authors： van Ham SM,van Alphen L,Mooi FR,van Putten JP

更新日期：1995-12-01 00:00:00

abstract：:Inbred strain 2 guinea pigs were vaccinated with Mycobacterium bovis BCG or were left unvaccinated and challenged 6 weeks later by the respiratory route with virulent Mycobacterium tuberculosis. By using a double rosette assay with isotype-specific antibody-coated ox and uncoated rabbit erythrocytes, the proportions o...

journal_title：Infection and immunity

authors： Bartow RA,McMurray DN

更新日期：1989-05-01 00:00:00

abstract：:Cholera toxin (CT) and related Escherichia coli enterotoxins LTI and LTIIb have a conserved hydrophobic region at the AB(5) interface postulated to be important for toxin assembly. Hydrophobic residue F223 in the A subunit of CT (CTA) as well as residues 174, L77, and T78 in the B subunit of CT (CTB) were replaced ind...

journal_title：Infection and immunity

authors： Tinker JK,Erbe JL,Hol WG,Holmes RK

更新日期：2003-07-01 00:00:00

abstract：:Myeloid differentiation protein 88 (MyD88) is a general adaptor for the signaling cascade through receptors of the Toll/IL-1R family. When infected with Leishmania major parasites, MyD88-deficient mice displayed a dramatically enhanced parasite burden in their tissues similar to that found in susceptible BALB/c mice. ...

journal_title：Infection and immunity

authors： Debus A,Gläsner J,Röllinghoff M,Gessner A

更新日期：2003-12-01 00:00:00

abstract：:Coxiella burnetii is an intracellular pathogen that replicates in a lysosome-derived vacuole. A determinant necessary for C. burnetii virulence is the Dot/Icm type IVB secretion system (T4SS). The Dot/Icm system delivers more than 100 proteins, called type IV effectors (T4Es), across the vacuolar membrane into the hos...

journal_title：Infection and immunity

authors： Crabill E,Schofield WB,Newton HJ,Goodman AL,Roy CR

更新日期：2018-03-22 00:00:00

abstract：:In this study, we examined the binding of Candida albicans synchronized yeast-phase cells to plastic, immobilized amino acids and bovine serum albumin (BSA) and quantified the binding by using an XTT tetrazolium salt assay and absorbance determination. Our results show that C. albicans binds efficiently and specifical...

journal_title：Infection and immunity

authors： Hawser SP,Islam K

更新日期：1998-01-01 00:00:00

abstract：:In gram-negative sepsis, the activation of polymorphonuclear leukocytes (PMN) by lipopolysaccharide (LPS) and the resulting production of superoxide and other oxygen radicals may be an important cause of tissue damage. A suppression of the PMN response to LPS stimulation would be therapeutically beneficial. The aim of...

journal_title：Infection and immunity

authors： Wagner DR,Heinrich D

更新日期：1994-10-01 00:00:00

abstract：:Two hybrid clones producing monoclonal antibodies (MAbs) raised against the purified enterotoxic hemolysin-phospholipase C (HlyPC) bifunctional molecule of a Vibrio cholerae O139 strain were used to study its enterotoxicity in relation to its hemolytic and enzymatic activities. Fab fragments of MAbs from ascites produ...

journal_title：Infection and immunity

authors： Pal S,Datta A,Nair GB,Guhathakurta B

更新日期：1998-08-01 00:00:00