Abstract:
OBJECTIVE:To determine if a pharmacist-initiated multidisciplinary strategy provides value for money compared to usual care in participants with previously undiagnosed knee osteoarthritis. METHODS:Pharmacies were randomly allocated to provide either 1) usual care and a pamphlet or 2) intervention care, which consisted of education, pain medication management by a pharmacist, physiotherapy-guided exercise, and communication with the primary care physician. Costs and quality-adjusted life-years (QALYs) were determined for patients assigned to each treatment and incremental cost-effectiveness ratios (ICERs) were determined. RESULTS:From the Ministry of Health perspective, the average patient in the intervention group generated slightly higher costs compared with usual care. Similar findings were obtained when using the societal perspective. The intervention resulted in ICERs of $232 (95% confidence interval [95% CI] -1,530, 2,154) per QALY gained from the Ministry of Health perspective and $14,395 (95% CI 7,826, 23,132) per QALY gained from the societal perspective, compared with usual care. CONCLUSION:A pharmacist-initiated, multidisciplinary program was good value for money from both the societal and Ministry of Health perspectives.
journal_name
Arthritis Care Res (Hoboken)journal_title
Arthritis care & researchauthors
Marra CA,Grubisic M,Cibere J,Grindrod KA,Woolcott JC,Gastonguay L,Esdaile JMdoi
10.1002/acr.22232subject
Has Abstractpub_date
2014-06-01 00:00:00pages
810-6issue
6eissn
2151-464Xissn
2151-4658journal_volume
66pub_type
杂志文章,随机对照试验abstract:OBJECTIVE:Despite the high prevalence of depression among vulnerable Hispanics with rheumatoid arthritis (RA), many do not disclose it or seek treatment. This study explored patient perceptions of depression, its association with their primary disease, barriers to disclosure, reasons for low utilization of mental healt...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.22462
更新日期:2015-04-01 00:00:00
abstract:OBJECTIVE:Health information technology (HIT) holds promise in increasing access to rheumatologists by improving the quality and efficiency of referrals, but few studies have examined its use for this purpose. We evaluated the use and impact of a novel electronic referral (eReferral) system in rheumatology in a safety-...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.22559
更新日期:2015-08-01 00:00:00
abstract:OBJECTIVE:To study the risk factors for revision of primary total hip replacement (THR) in a US population-based sample. METHODS:Using Medicare claims, we identified beneficiaries from 29 US states who underwent primary THR between July 1, 1995 and June 30, 1996, with followup through December 31, 2008. Potential case...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.21760
更新日期:2012-12-01 00:00:00
abstract:BACKGROUND:Hypertensive disorders of pregnancy (HDP) increase cardiovascular disease (CVD) risk. Pregnancy morbidities, including preeclampsia, and CVD are common in systemic lupus erythematosus (SLE). Possible connections are important to explore. In a population-based cohort, we investigated whether HDP is associated...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.24160
更新日期:2020-01-31 00:00:00
abstract:OBJECTIVE:To identify and evaluate the measurement properties of self-report physical activity instruments suitable for patients with osteoarthritis (OA). METHODS:We conducted a comprehensive 2-stage systematic review using multiple electronic databases, from inception until July 2018. In the stage 1 review, we sought...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.23787
更新日期:2019-02-01 00:00:00
abstract:OBJECTIVE:To examine clinical characteristics as possible predictors of long-term treatment continuation with adalimumab, etanercept, and infliximab in ankylosing spondylitis (AS) patients who had never taken biologics treated in clinical practice. METHODS:Patients in southern Sweden with active AS starting biologic t...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.20258
更新日期:2010-10-01 00:00:00
abstract:OBJECTIVE:To evaluate the impact of anti-tumor necrosis factor (anti-TNF) therapies on quality of life (QOL) and functional status in psoriatic arthritis (PsA) patients and study potential predictors for QOL improvements. METHODS:The study was based on a cohort of 596 PsA patients receiving anti-TNF therapies. Changes...
journal_title:Arthritis care & research
pub_type: 杂志文章,多中心研究
doi:10.1002/acr.20104
更新日期:2010-03-01 00:00:00
abstract:OBJECTIVE:To determine whether calcinosis and acro-osteolysis are related to specific nailfold videocapillaroscopy (NVC) features in patients with systemic sclerosis (SSc; scleroderma). METHODS:NVC and bilateral hand radiographs were systematically performed in 155 consecutively recruited patients with SSc during a 24...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.22672
更新日期:2016-03-01 00:00:00
abstract:OBJECTIVE:To describe long-term physical functioning and its association with somatic comorbidity and comorbid depression in patients with established rheumatoid arthritis (RA). METHODS:Longitudinal data over a period of 11 years were collected from 882 patients with RA at study inclusion. Patient-reported outcomes we...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.21950
更新日期:2013-07-01 00:00:00
abstract:OBJECTIVE:To evaluate the effects of valgus knee bracing on pain and function, and compliance and complications, in patients with medial knee osteoarthritis (OA). METHODS:A meta-analysis of randomized controlled trials that compared changes in patient-reported pain and/or function in patients with medial knee OA was p...
journal_title:Arthritis care & research
pub_type: 杂志文章,meta分析
doi:10.1002/acr.22472
更新日期:2015-04-01 00:00:00
abstract:OBJECTIVE:To compare the time-varying behavior of maximum toe-out angle, lateral trunk lean (over the stance leg), and pelvic obliquity (rise and drop on the swing leg) during prolonged walking in participants with and without medial compartment knee osteoarthritis (OA), and to explore correlations between these gait c...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.21584
更新日期:2012-04-01 00:00:00
abstract:OBJECTIVE:The hepatitis B virus (HBV) testing rates and patterns in rheumatoid arthritis (RA) patients starting disease-modifying antirheumatic drugs (DMARDs) have not been well studied. We describe and compare the practice patterns of HBV testing among RA patients in the US and Taiwan. METHODS:We conducted a retrospe...
journal_title:Arthritis care & research
pub_type: 杂志文章,多中心研究
doi:10.1002/acr.23241
更新日期:2018-01-01 00:00:00
abstract:OBJECTIVE:Despite the joint pain and significant dysfunction that characterizes arthritis, many people with arthritis continue to carry out everyday duties and responsibilities. Our objective was to describe participation in informal caregiving (unpaid assistance to someone with a health issue or limitation) among peop...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.24329
更新日期:2020-05-31 00:00:00
abstract:OBJECTIVE:Anti-citrullinated peptide antibody (ACPA) and rheumatoid factor (RF) are markers to rheumatoid arthritis (RA). Smoking and shared epitope (SE) in HLA-DRB1 are associated with the production of these autoantibodies in RA. Detailed distribution and characterization of ACPA and RF in the general population have...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.22385
更新日期:2014-12-01 00:00:00
abstract:OBJECTIVE:To examine patient willingness and a possible shift in willingness for surgery and to investigate factors associated with this shift, following participation in the digital nonsurgical osteoarthritis (OA) treatment program Joint Academy. METHODS:A total of 458 individuals (mean ± SD age 62 ± 5.6 years, 67% w...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.23772
更新日期:2019-09-01 00:00:00
abstract:OBJECTIVE:To determine if baseline 3-dimensional (3-D) biomechanical gait patterns differed between those patients with moderate knee osteoarthritis (OA) who progressed to total knee arthroplasty (TKA) and those that did not, and whether these differences had predictive value. METHODS:Fifty-four patients with knee OA ...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.22564
更新日期:2015-07-01 00:00:00
abstract:OBJECTIVE:To estimate the prevalence of overweight and obese Canadians with arthritis and to describe their use of arthritis self-management strategies, as well as explore the factors associated with not engaging in any self-management strategies. METHODS:Respondents to the 2009 Survey on Living with Chronic Diseases ...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.20654
更新日期:2012-02-01 00:00:00
abstract:OBJECTIVE:To test the hypothesis that oxidative stress is increased in patients with rheumatoid arthritis (RA) due to increased inflammation and contributes to the pathogenesis of atherosclerosis. METHODS:The independent association between urinary F₂-isoprostane excretion, a measure of oxidative stress, and RA was te...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.20237
更新日期:2010-10-01 00:00:00
abstract:OBJECTIVE:To summarize the state of knowledge regarding the economic burden of systemic lupus erythematosus (SLE) and to evaluate the quality of cost-of-illness (COI) studies conducted to date. METHODS:Relevant literature was retrieved from the PubMed database in April 2010. The evaluation of identified articles was b...
journal_title:Arthritis care & research
pub_type: 杂志文章,评审
doi:10.1002/acr.20410
更新日期:2011-05-01 00:00:00
abstract:OBJECTIVE:To determine whether there is a temporal association between arthritis and uveitis activity among children with juvenile idiopathic arthritis-associated uveitis (JIA-U). METHODS:Uveitis and arthritis data from JIA-U patients ≤21 years were collected from 7/2013-12/2019 at a tertiary care center. Arthritis ac...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.24483
更新日期:2020-10-12 00:00:00
abstract:OBJECTIVE:Total knee arthroplasty (TKA) is a widely utilized and effective treatment option for end-stage knee osteoarthritis (OA). Knee OA is more prevalent among women compared to men, but there are limited data on the sex differences in surgical outcomes after primary TKA. METHODS:Our sample consisted of all primar...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.21953
更新日期:2013-07-01 00:00:00
abstract:OBJECTIVE:Localized scleroderma can negatively affect children's quality of life (QoL), but predictors of impact have not been well described. We sought to identify predictors of QoL impact in juvenile localized scleroderma patients. METHODS:We analyzed longitudinal data from a single-center cohort of juvenile localiz...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.23101
更新日期:2017-07-01 00:00:00
abstract:OBJECTIVE:To determine the extent to which thigh intermuscular fat (IMF) and quadriceps muscle (QM) volumes explained variance in knee extensor strength and physical performance in women with radiographic knee osteoarthritis (ROA) and without. METHODS:Baseline data from 125 women (age ≥50 years) in the Osteoarthritis ...
journal_title:Arthritis care & research
pub_type: 杂志文章,多中心研究
doi:10.1002/acr.21868
更新日期:2013-01-01 00:00:00
abstract:OBJECTIVE:Rheumatoid arthritis (RA) is the most common inflammatory disorder affecting the cervical spine. The purpose of this study was to characterize the atloaxial involvement with magnetic resonance imaging (MRI) in patients with early RA at the moment of diagnosis and after 18 months of a tight control therapy. M...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.20573
更新日期:2011-11-01 00:00:00
abstract:OBJECTIVE:Prompt treatment for lupus is important to prevent morbidity. A potential barrier to early treatment of pediatric lupus is delayed presentation to a pediatric rheumatologist. To better understand factors contributing to delayed presentation among pediatric lupus patients, we examined differences in demographi...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.23285
更新日期:2018-03-01 00:00:00
abstract:OBJECTIVE:To determine the influence of socioeconomic factors on disease activity in a Latin American (LA) early rheumatoid arthritis (RA) multinational inception cohort at baseline. METHODS:Clinical evaluation, ethnicity, socioeconomic status (SES), 4-variable Disease Activity Score in 28 joints using the erythrocyte...
journal_title:Arthritis care & research
pub_type: 杂志文章,多中心研究
doi:10.1002/acr.21680
更新日期:2012-08-01 00:00:00
abstract:OBJECTIVE:Systemic lupus erythematosus (SLE) predominantly affects women. Clinical phenotype and outcomes in SLE may vary by sex and are further complicated by unique concerns that are dependent upon sex-defined roles. We aimed to describe sex differences in disease-specific quality of life (QoL) assessment scores usin...
journal_title:Arthritis care & research
pub_type: 杂志文章,多中心研究
doi:10.1002/acr.23588
更新日期:2019-12-01 00:00:00
abstract:OBJECTIVE:To examine the external validity of the Lupus Impact Tracker (LIT), a systemic lupus erythematosus (SLE)-specific, health-related quality of life (HRQoL) tool in a population-based cohort of patients with SLE in Atlanta, Georgia. We modeled the association of LIT scores with patient-reported measures of SLE a...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.23009
更新日期:2017-06-01 00:00:00
abstract:OBJECTIVE:To determine the prevalence of severe fatigue and fatigue-related limitations among adolescents with juvenile idiopathic arthritis (JIA) and other pediatric rheumatic diseases (PRDs). In addition, we assessed the effect of disease activity and pain on the severity of fatigue. METHODS:This cross-sectional stu...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.22710
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVE:Hallux valgus (HV) is common in older adults, but limited studies of risk factors have reported conflicting results. This cross-sectional analysis examined the association of HV with foot pain and other characteristics in older adults. METHODS:The population-based Framingham Foot Study assessed HV, foot pain...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.22391
更新日期:2014-12-01 00:00:00