Adipokines and lipoproteins: modulation by antihyperglycemic and hypolipidemic agents.

abstract：BACKGROUND:We undertook a study to assess β-cell function, metabolic and immunological features of patients with latent autoimmune diabetes in adults (LADA) and investigate heterogeneity within LADA based on low and high glutamic acid decarboxylase autoantibodies (GADA) titers. METHODS:A total of 139 patients with adu...

journal_title：Metabolic syndrome and related disorders

authors： Kumar A,de Leiva A

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVE:Patients with metabolic syndrome are at increased risk of atherosclerotic coronary heart disease, often have mixed dyslipidemia, and may thus require more aggressive treatment of multiple lipid parameters. The objective of this investigation was to compare the treatment response of ezetimibe co-administered w...

journal_title：Metabolic syndrome and related disorders

authors： Bays HE,Shah A,Macdonell G,Taggart WV,Gumbiner B

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:In the fed state, the glucose disposal action of insulin can be attributed in approximately equal part to the direct action of insulin and to a hepatic insulin sensitizing substance (HISS) that acts selectively on skeletal muscle. HISS action is absent in the 24-hour fasted state. The objective of this study...

journal_title：Metabolic syndrome and related disorders

authors： Lautt WW,Legare DJ,Reid MA,Sadri P,Ting JW,Prieditis H

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:The purpose of this cross-sectional study was to examine the impact of below-average cardiovascular fitness and inactivity on the metabolic syndrome among an understudied population-undergraduate men and women, ages 18-24 years. METHODS:Between January, 2010, and May, 2012, we assessed anthropometric, bioch...

journal_title：Metabolic syndrome and related disorders

authors： Morrell JS,Cook SB,Carey GB

更新日期：2013-10-01 00:00:00

abstract：: Background: Ethnic variations have been reported in allelic frequencies of the leptin receptor gene (LEPR) with population-specific effects. We aimed to explore the association of LEPR polymorphisms with obesity, metabolic syndrome (MetS), and leptin levels in Afro-Caribbe...

journal_title：Metabolic syndrome and related disorders

authors： Foucan L,Bassien-Capsa V,Rambhojan C,Lacorte JM,Larifla L

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:Fibronectin type III domain containing 5 (FNDC5) and its protein product Irisin are therapeutic targets for obesity-associated disorders. Irisin plays an important role in energy regulation, inducing browning of white adipocytes, and improving obesity. We aimed to investigate the association between muscle I...

journal_title：Metabolic syndrome and related disorders

authors： de Macêdo SM,Lelis DF,Mendes KL,Fraga CAC,Brandi IV,Feltenberger JD,Farias LC,Guimarães ALS,de Paula AMB,Santos SHS

更新日期：2017-05-01 00:00:00

abstract：AIM:The objective of this study was to estimate basal insulin resistance (IR) and insulin secretion (IS) in Nigerians with type 2 diabetes mellitus (T2DM). METHODS:The homeostasis model assessment (HOMA) method was used to estimate basal IR and IS in 146 Nigerians with T2DM and in 33 controls at the University of Nige...

journal_title：Metabolic syndrome and related disorders

authors： Oli JM,Adeyemo AA,Okafor GO,Ofoegbu EN,Onyenekwe B,Chukwuka CJ,Onwasigwe CN,Ufelle S,Chen G,Rotimi CN

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:This study investigates ethnic disparities in metabolic syndrome in Malaysia. METHODS:Data were obtained from the Malaysia Non-Communicable Disease Surveillance-1 (2005/2006). Logistic regressions of metabolic syndrome health risks on sociodemographic and health-lifestyle factors were conducted using a mult...

journal_title：Metabolic syndrome and related disorders

authors： Tan AK,Dunn RA,Yen ST

更新日期：2011-12-01 00:00:00

abstract：:Over the past two decades, there has been a striking increase in the number of people with metabolic syndrome. The prevalence of metabolic syndrome varies due to lack of an internationally agreed upon definition. Considering the increased cardiovascular risk among Asian people, a lower cutoff for waist circumference i...

journal_title：Metabolic syndrome and related disorders

authors： Basit A,Shera AS

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:It is unknown whether severe sarcopenia produces unfavorable effects on cardiovascular risk factors. To examine the influence of severe and moderate sarcopenia on selected cardiovascular risk factors, 687 men were screened; those exhibiting clinically relevant diseases and higher body fat percentage (>25% fa...

journal_title：Metabolic syndrome and related disorders

authors： Abe T,Thiebaud RS,Loenneke JP,Bemben MG,Loftin M,Fukunaga T

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:We compared the lipid-altering effects of ezetimibe/simvastatin (EZE/SIMVA) co-administered with fenofibrate (FENO) in mixed hyperlipidemic patients with (MetS) versus those without MetS. METHODS:A total of 611 patients, 20 to 79 years old, with LDL-C 130-220 mg/dL (100-180 mg/dL for patients with type 2 di...

journal_title：Metabolic syndrome and related disorders

authors： Gil-Extremera B,Mendez G,Zakson M,Meehan A,Shah A,Lin J,Mitchel Y

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:Variants in the fat mass and obesity-associated (FTO) gene are associated with obesity and type 2 diabetes mellitus. AIM OF THE STUDY:This study aims to assess the association of the rs9939609 variant and haplotypes in FTO gene with metabolic syndrome (MetS) components in a Tunisian population sample. METH...

journal_title：Metabolic syndrome and related disorders

authors： Elouej S,Belfki-Benali H,Nagara M,Lasram K,Attaoua R,Sallem OK,Kamoun I,Chargui M,Romdhane L,Jamoussi H,Turki Z,Abid A,Ben Slama C,Bahri S,Abdelhak S,Grigorescu F,Ben Romdhane H,Kefi R

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Resistin is a peptide hormone secreted mainly from human monocytes and macrophages. It has an unclear association with the metabolic syndrome, which is a cluster of cardiovascular risk factors such as glucose intolerance, central obesity, insulin resistance, dyslipidemia, and hypertension. We examined the as...

journal_title：Metabolic syndrome and related disorders

authors： Malo E,Ukkola O,Jokela M,Moilanen L,Kähönen M,Nieminen MS,Salomaa V,Jula A,Kesäniemi YA

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:Overall hemostatic potential (OHP) captures all factors that affect coagulation and fibrinolysis cascade. It has not yet been assessed in polycystic ovary syndrome (PCOS). The aim of the study was to identify the relationship of OHP with a syndrome per se and body mass index (BMI). METHODS:In 90 women with ...

journal_title：Metabolic syndrome and related disorders

authors： Rakusa M,Jensterle M,Božič-Mijovski M,Janez A

更新日期：2017-05-01 00:00:00

abstract：:Nonalcoholic fatty liver disease (NAFLD) is a major form of chronic liver disease in adults and children. It is one of the consequences of the current obesity epidemic, and can progress to nonalcoholic steatohepatitis (NASH), characterized by steatosis, inflammation, and progressive fibrosis, ultimately leading to cir...

journal_title：Metabolic syndrome and related disorders

authors： Jiang J,Torok N

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:Patients with morbid obesity have a high risk of developing type 2 diabetes mellitus (T2DM). Important risk factors include body mass index (BMI), waist circumference, and insulin resistance. In this prospective study, we investigated if preoperative lifestyle changes followed by bariatric surgery could redu...

journal_title：Metabolic syndrome and related disorders

authors： Nestvold TK,Nielsen EW,Lappegård KT

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Isolated postchallenge hyperglycemia (IPH) is an early form of type 2 diabetes with fasting glucose <126 mg/dL and 2-hr postchallenge glucose ≥200 mg/dL. The purpose of this study was to explore the relationships of high-sensitivity C-reactive protein (hsCRP) with IPH. METHODS:We recruited 476 naturally pos...

journal_title：Metabolic syndrome and related disorders

authors： Hwu CM,Lin YC,Lin MW

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:The aim of this study was to study (1) weight gain in type 2 diabetics with different treatment modalities and (2) relationship of weight gain with stable adult weight. METHODS:A study of 469 type 2 diabetics on regular follow-up was undertaken to determine the effect of modality of therapy on patient's wei...

journal_title：Metabolic syndrome and related disorders

authors： Chandalia HB,Lamba PS,Chandalia SH,Singh DK,Modi SV,Shaikh SA

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:Growth arrest-specific 6 (Gas6) is a vitamin K-dependent protein secreted by immune cells, endothelial cells, vascular smooth muscle cells, and adipocytes. Recent studies indicate that Gas6 and receptors of the TAM (Tyro3, Axl, and Mer) family may be involved in the pathogenesis of obesity, systemic inflamma...

journal_title：Metabolic syndrome and related disorders

authors： Li YH,Lu CH,Lin FH,Su SC,Liu JS,Hsieh CH,Hung YJ,Shieh YS,Lee CH

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:Multiple abnormal metabolic traits are found together or "cluster" within individuals more often than is predicted by chance. The individual and combined role of adiposity and insulin resistance (IR) on metabolic trait clustering is uncertain. We tested the hypothesis that change in trait clustering is a fun...

journal_title：Metabolic syndrome and related disorders

authors： Rutter MK,Sullivan LM,Fox CS,Wilson PW,Nathan DM,Vasan RS,D'Agostino RB Sr,Meigs JB

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:Concomitant supplementation of 1.5% docosahexaenoic acid (22:6 n-3; DHA) with 0.5% t10, c12-conjugated linoleic acid (18:2 n-6; CLA) prevented the CLA-induced increase in expression of hepatic genes involved in fatty acid synthesis and the decrease in expression of genes involved in fatty acid oxidation. The...

journal_title：Metabolic syndrome and related disorders

authors： Fedor DM,Adkins Y,Newman JW,Mackey BE,Kelley DS

更新日期：2013-02-01 00:00:00

abstract：: Background: Evidence suggests that metabolic syndrome (MetS) is highly prevalent in patients with obstructive sleep apnea syndrome (OSAS) and chronic obstructive pulmonary disease (COPD). However, data on the prevalence of MetS in patients having both OSAS and COPD, or ove...

journal_title：Metabolic syndrome and related disorders

authors： Archontogeorgis K,Voulgaris A,Papanas N,Nena E,Xanthoudaki M,Pataka A,Schiza S,Rizzo M,Froudarakis ME,Steiropoulos P

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:The circadian pattern of adipokines is blunted in obese subjects, and we tested the hypothesis that bariatric surgery could normalize the 24-hr pattern of adipokines. Therefore, this study was designed to examine the early impact of the newly designed sleeve gastrectomy with transit bipartition (SGTB) surger...

journal_title：Metabolic syndrome and related disorders

authors： Costa Justus JF,Ligocki Campos AC,Figueroa AL,Gomis R,Santo MA,Fávero GM,Milléo FQ,Vieira E

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:The fetal origins hypothesis indicates that morphometric evidence of fetal nutritional deprivation is predictive of excessive weight gain/obesity, insulin resistance, and cardiovascular disease after birth. However, it is unclear whether these effects are present in offspring with "normal" birth weights in c...

journal_title：Metabolic syndrome and related disorders

authors： Clapp Iii JF,Lopez B

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND:The aim of this study was to discover the association of serum high-sensitivity C-reactive protein (hsCRP) with various risk factors for metabolic syndrome in an urban population of Karachi, Pakistan. METHOD:In this cross-sectional study, 337 healthy adults (108 males and 229 females, mean age 40.7 ± 14.2 y...

journal_title：Metabolic syndrome and related disorders

authors： Riaz M,Fawwad A,Hydrie MZ,Basit A,Shera AS

更新日期：2011-06-01 00:00:00

abstract：UNLABELLED:Abstract Background: Skeletal muscle adipose tissue (AT) infiltration, or myosteatosis, appears to be greater in African compared with European ancestry individuals and may play a role in type 2 diabetes mellitus (T2DM), a disease that disproportionally affects African ancestry populations. Inflammation is o...

journal_title：Metabolic syndrome and related disorders

authors： Miljkovic I,Kuipers AL,Kammerer CM,Wang X,Bunker CH,Patrick AL,Wheeler VW,Kuller LH,Evans RW,Zmuda JM

更新日期：2011-08-01 00:00:00

abstract：AIM:This study aimed to develop age- and sex-specific reference values for body mass index (BMI), percentage body fat (%BF), waist circumference, waist-to-hip circumference ratio, and triceps and subscapular skinfold thicknesses for 14- to 18-year-old urban Asian Indians and to develop BMI cut-off points using specific...

journal_title：Metabolic syndrome and related disorders

authors： Pandey RM,Madhavan M,Misra A,Kalaivani M,Vikram NK,Dhingra V

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:Metabolic syndrome is increasingly common in U.S. adolescents and has been linked to cognitive dysfunction. Purpose of this study is to explore associations between metabolic syndrome and cognitive impairment in U.S. adolescents using population-based data. STUDY DESIGN:Participants included adolescents age...

journal_title：Metabolic syndrome and related disorders

authors： Rubens M,Ramamoorthy V,Saxena A,George F,Shehadeh N,Attonito J,McCoy HV,Beck-Sagué CM

更新日期：2016-10-01 00:00:00

abstract：:Omega-3s are found in oily fish. We have drastically reduced our intake of fish during the last century. Many of us therefore suffer from a deficiency of omega-3s, which has consequences for health. In this review, we focus on structure-functional relationships and the relation of omega-3s to the metabolic syndrome, i...

journal_title：Metabolic syndrome and related disorders

authors： Saldeen P,Saldeen T

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:It has been shown that elevated levels of alanine and aspartate aminotransferases (ALT and AST) are associated with insulin resistance and type 2 diabetes mellitus; however, the pattern of this association in diabetic patients with negative or mild steatosis is not well understood. The aim of this study was ...

journal_title：Metabolic syndrome and related disorders

authors： Esteghamati A,Noshad S,Khalilzadeh O,Khalili M,Zandieh A,Nakhjavani M

更新日期：2011-04-01 00:00:00