Nonalcoholic steatohepatitis and the metabolic syndrome.

abstract：AIM:The objective of this study was to estimate basal insulin resistance (IR) and insulin secretion (IS) in Nigerians with type 2 diabetes mellitus (T2DM). METHODS:The homeostasis model assessment (HOMA) method was used to estimate basal IR and IS in 146 Nigerians with T2DM and in 33 controls at the University of Nige...

journal_title：Metabolic syndrome and related disorders

authors： Oli JM,Adeyemo AA,Okafor GO,Ofoegbu EN,Onyenekwe B,Chukwuka CJ,Onwasigwe CN,Ufelle S,Chen G,Rotimi CN

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:The fetal origins hypothesis indicates that morphometric evidence of fetal nutritional deprivation is predictive of excessive weight gain/obesity, insulin resistance, and cardiovascular disease after birth. However, it is unclear whether these effects are present in offspring with "normal" birth weights in c...

journal_title：Metabolic syndrome and related disorders

authors： Clapp Iii JF,Lopez B

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND:Metabolic syndrome occurs commonly in the United States. The purpose of this study was to measure the prevalence of metabolic syndrome among American Indian and Alaska Native people. METHODS:We measured the prevalence rates of metabolic syndrome, as defined by the National Cholesterol Education Program, amo...

journal_title：Metabolic syndrome and related disorders

authors： Schumacher C,Ferucci ED,Lanier AP,Slattery ML,Schraer CD,Raymer TW,Dillard D,Murtaugh MA,Tom-Orme L

更新日期：2008-12-01 00:00:00

abstract：: Background: Diabetes mellitus (DM) is associated with a higher prevalence of metabolic syndrome (MS) and cardiovascular mortality. However, few Brazilian studies evaluated MS in diabetic individuals with cardiovascular disease (CVD). Nevertheless, the objective of this stu...

journal_title：Metabolic syndrome and related disorders

authors： de Brito Gonçalves Nascimento L,Sahade V,Weber B,Pinheiro JMF,Dias LPP,Figueiredo Neto JA,Carlos Sobral Sousa A,Pinho CPS,Luna AB,Vasconcelos SML,Dantas CF,Penafort AM,Carlos DMO,Daltro C

更新日期：2021-02-01 00:00:00

abstract：BACKGROUND:Fibronectin type III domain containing 5 (FNDC5) and its protein product Irisin are therapeutic targets for obesity-associated disorders. Irisin plays an important role in energy regulation, inducing browning of white adipocytes, and improving obesity. We aimed to investigate the association between muscle I...

journal_title：Metabolic syndrome and related disorders

authors： de Macêdo SM,Lelis DF,Mendes KL,Fraga CAC,Brandi IV,Feltenberger JD,Farias LC,Guimarães ALS,de Paula AMB,Santos SHS

更新日期：2017-05-01 00:00:00

abstract：: Background: Obesity causes significant morbidity and mortality and continues to be a significant public health concern. Unfortunately, lifestyle modification and pharmacotherapy do not produce durable results. This has led to bariatric surgical procedures playing an increa...

journal_title：Metabolic syndrome and related disorders

authors： Kittah E,Camilleri M,Jensen MD,Vella A

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:The increased prevalence of overweight and obesity has reached alarming proportions worldwide and has serious health implications, including an association with an increase in metabolic syndrome. Among the methods to control metabolic syndrome, bariatric surgery plays an important role and can provide a sign...

journal_title：Metabolic syndrome and related disorders

authors： Saboya C,Arasaki CH,Matos D,Lopes-Filho GJ

更新日期：2012-08-01 00:00:00

abstract：PURPOSE:Obesity and high body fat are related to diabetes and metabolic syndrome (MetS) in all ethnic groups. Based on the International Diabetes Federation (IDF) definition of MetS, the aim of the present study was to compare body adiposity indexes (BAIs) and to assess their various cutoff values for the prediction of...

journal_title：Metabolic syndrome and related disorders

authors： Correa-Bautista JE,González-Ruíz K,Vivas A,Triana-Reina HR,Martínez-Torres J,Prieto-Benavides DH,Carrillo HA,Ramos-Sepúlveda JA,Afanador-Rodríguez MI,Villa-González E,García-Hermoso A,Ramírez-Vélez R

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:The relationship between the metabolic syndrome and subclinical atherosclerosis among elderly people remains controversial. We seek to investigate the associations of metabolic syndrome and its components with subclinical carotid atherosclerosis in older people living in rural China. METHODS:This cross-sect...

journal_title：Metabolic syndrome and related disorders

authors： Yan Z,Liang Y,Jiang H,Cai C,Sun B,Qiu C

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:The aim of this study was to investigate insulin sensitivity and secretion in lean and obese Asian (Thai) type 2 diabetic patients. METHODS:Insulin sensitivity and insulin secretion was assessed with the hyperinsulinemic euglycemic (80 mU/m(2) per min) and hyperglycemic clamp technique in 9 lean and 10 obes...

journal_title：Metabolic syndrome and related disorders

authors： Suraamornkul S,Kwancharoen R,Ovartlarnporn M,Rawdaree P,Bajaj M

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:Concomitant supplementation of 1.5% docosahexaenoic acid (22:6 n-3; DHA) with 0.5% t10, c12-conjugated linoleic acid (18:2 n-6; CLA) prevented the CLA-induced increase in expression of hepatic genes involved in fatty acid synthesis and the decrease in expression of genes involved in fatty acid oxidation. The...

journal_title：Metabolic syndrome and related disorders

authors： Fedor DM,Adkins Y,Newman JW,Mackey BE,Kelley DS

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Metabolic syndrome is one of the most important health issues worldwide. Obesity causes insulin resistance, hyperlipidemia, diabetes, and various diseases throughout the body. The liver phenotype, which is called nonalcoholic steatohepatitis (NASH), frequently progresses to hepatocellular carcinoma. We recen...

journal_title：Metabolic syndrome and related disorders

authors： Watanabe S,Takahashi T,Ogawa H,Uehara H,Tsunematsu T,Baba H,Morimoto Y,Tsuneyama K

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Variants in the fat mass and obesity-associated (FTO) gene are associated with obesity and type 2 diabetes mellitus. AIM OF THE STUDY:This study aims to assess the association of the rs9939609 variant and haplotypes in FTO gene with metabolic syndrome (MetS) components in a Tunisian population sample. METH...

journal_title：Metabolic syndrome and related disorders

authors： Elouej S,Belfki-Benali H,Nagara M,Lasram K,Attaoua R,Sallem OK,Kamoun I,Chargui M,Romdhane L,Jamoussi H,Turki Z,Abid A,Ben Slama C,Bahri S,Abdelhak S,Grigorescu F,Ben Romdhane H,Kefi R

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:We evaluated structural microvascular alterations in the skeletal muscle and left ventricle, as well as endothelium-dependent microvascular reactivity in the skeletal muscle, of diabetic rats subjected to long-term aerobic exercise training. METHODS:Diabetes was experimentally induced by a combination of a ...

journal_title：Metabolic syndrome and related disorders

authors： Machado MV,Martins RL,Borges J,Antunes BR,Estato V,Vieira AB,Tibiriçá E

更新日期：2016-08-01 00:00:00

abstract：:The metabolic syndrome (MS) is a clustering of cardiovascular risk factors, with insulin resistance as a major feature. This syndrome has been variously defined, but generally consists of 3 or more of the following components: hyperglycemia, hypertension, hypertriglyceridemia, low HDL, and increased abdominal circumfe...

journal_title：Metabolic syndrome and related disorders

authors： Sutherland JP,McKinley B,Eckel RH

更新日期：2004-06-01 00:00:00

abstract：:Even though insulin resistance, cardiovascular disease (CVD), and type 2 diabetes (T2D) are associated with hypertriglyceridemia, blacks with these conditions usually have normal triglyceride (TG) levels. This is often called a lipid paradox. More precisely, it is a "TG paradox." The pathways that lead to hypertriglyc...

journal_title：Metabolic syndrome and related disorders

authors： Yu SS,Castillo DC,Courville AB,Sumner AE

更新日期：2012-04-01 00:00:00

abstract：AIM:This study aimed to develop age- and sex-specific reference values for body mass index (BMI), percentage body fat (%BF), waist circumference, waist-to-hip circumference ratio, and triceps and subscapular skinfold thicknesses for 14- to 18-year-old urban Asian Indians and to develop BMI cut-off points using specific...

journal_title：Metabolic syndrome and related disorders

authors： Pandey RM,Madhavan M,Misra A,Kalaivani M,Vikram NK,Dhingra V

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:In adult studies, obese subjects with nonalcoholic fatty liver disease (NAFLD) have been shown to have poor sperm quality, and lower testosterone and luteinizing hormone levels. The aim of this study was to investigate the pubertal status and gonadal functions in obese boys with NAFLD. MATERIALS AND METHODS...

journal_title：Metabolic syndrome and related disorders

authors： Kurku H,Atar M,Pirgon Ö,Büyükinan M,Erdem SS,Deniz İ,Gederet YT

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to examine effect modifiers of the relationship between family history of diabetes, a proxy for genetic predisposition, and the metabolic syndrome. METHODS:Subjects were a cross-sectional sample of 205 Mexican-Americans patients of the San Ysidro Health Center in San Diego Coun...

journal_title：Metabolic syndrome and related disorders

authors： Nelson T,Perez A,Alcaraz J,Talavera G,McCarthy JJ

更新日期：2007-09-01 00:00:00

abstract：: Background: Ethnic variations have been reported in allelic frequencies of the leptin receptor gene (LEPR) with population-specific effects. We aimed to explore the association of LEPR polymorphisms with obesity, metabolic syndrome (MetS), and leptin levels in Afro-Caribbe...

journal_title：Metabolic syndrome and related disorders

authors： Foucan L,Bassien-Capsa V,Rambhojan C,Lacorte JM,Larifla L

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVE:Patients with metabolic syndrome are at increased risk of atherosclerotic coronary heart disease, often have mixed dyslipidemia, and may thus require more aggressive treatment of multiple lipid parameters. The objective of this investigation was to compare the treatment response of ezetimibe co-administered w...

journal_title：Metabolic syndrome and related disorders

authors： Bays HE,Shah A,Macdonell G,Taggart WV,Gumbiner B

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Patients with morbid obesity have a high risk of developing type 2 diabetes mellitus (T2DM). Important risk factors include body mass index (BMI), waist circumference, and insulin resistance. In this prospective study, we investigated if preoperative lifestyle changes followed by bariatric surgery could redu...

journal_title：Metabolic syndrome and related disorders

authors： Nestvold TK,Nielsen EW,Lappegård KT

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:In the fed state, the glucose disposal action of insulin can be attributed in approximately equal part to the direct action of insulin and to a hepatic insulin sensitizing substance (HISS) that acts selectively on skeletal muscle. HISS action is absent in the 24-hour fasted state. The objective of this study...

journal_title：Metabolic syndrome and related disorders

authors： Lautt WW,Legare DJ,Reid MA,Sadri P,Ting JW,Prieditis H

更新日期：2005-01-01 00:00:00

abstract：:The successful introduction of highly active antiretroviral therapy (HAART), a combination of potent antiretroviral agents, including protease inhibitors, nucleoside reverse transcriptase inhibitors, and nonnucleoside reverse transcriptase inhibitors, has impacted positively on morbidity and mortality among human immu...

journal_title：Metabolic syndrome and related disorders

authors： Anuurad E,Semrad A,Berglund L

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:The aim of this study was to study (1) weight gain in type 2 diabetics with different treatment modalities and (2) relationship of weight gain with stable adult weight. METHODS:A study of 469 type 2 diabetics on regular follow-up was undertaken to determine the effect of modality of therapy on patient's wei...

journal_title：Metabolic syndrome and related disorders

authors： Chandalia HB,Lamba PS,Chandalia SH,Singh DK,Modi SV,Shaikh SA

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:The use of chromium-containing dietary supplements is widespread among patients with type 2 diabetes. Chromium's effects in patients at high risk for developing diabetes, especially those with metabolic syndrome, is unknown. The objective of this study was to determine the effects of chromium picolinate (CrP...

journal_title：Metabolic syndrome and related disorders

authors： Iqbal N,Cardillo S,Volger S,Bloedon LT,Anderson RA,Boston R,Szapary PO

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:The purpose of this cross-sectional study was to examine the impact of below-average cardiovascular fitness and inactivity on the metabolic syndrome among an understudied population-undergraduate men and women, ages 18-24 years. METHODS:Between January, 2010, and May, 2012, we assessed anthropometric, bioch...

journal_title：Metabolic syndrome and related disorders

authors： Morrell JS,Cook SB,Carey GB

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:We compared the lipid-altering effects of ezetimibe/simvastatin (EZE/SIMVA) co-administered with fenofibrate (FENO) in mixed hyperlipidemic patients with (MetS) versus those without MetS. METHODS:A total of 611 patients, 20 to 79 years old, with LDL-C 130-220 mg/dL (100-180 mg/dL for patients with type 2 di...

journal_title：Metabolic syndrome and related disorders

authors： Gil-Extremera B,Mendez G,Zakson M,Meehan A,Shah A,Lin J,Mitchel Y

更新日期：2007-12-01 00:00:00

abstract：:In this communication we discuss the role of the gut for the development of type 2 diabetes mellitus (T2DM). Gastric emptying rates importantly determine postprandial glucose excursions and regulate postprandial secretion of the incretin hormones, glucose-dependent insulinotropic polypeptide (GIP), and glucagon-like p...

journal_title：Metabolic syndrome and related disorders

authors： Holst JJ,Pedersen J,Wewer Albrechtsen NJ,Knop FK

更新日期：2017-08-01 00:00:00

abstract：:We assessed 17 middle-aged and older individuals (58.0 +/- 7.9 years, 7 females) at risk for cardiovascular disease regarding: (1) Whether carotid artery stiffness (cAS) would be reduced with a 1-year lifestyle modification program, (2) to what degree cAS would return following washout (mean of 26.9 +/- 4.0 months) fr...

journal_title：Metabolic syndrome and related disorders

authors： Aizawa K,Shoemaker JK,Overend TJ,Petrella RJ

更新日期：2010-08-01 00:00:00