Abstract:
:The human brain is a complex network that is known to be affected by normal aging. Graph-based analysis has been used to estimate functional brain network efficiency and effects of normal aging on small-worldness have been reported. This relationship is further investigated here along with network modularity, a statistic reflecting how well a network is organized into modules of densely interconnected nodes. Modularity has previously been observed to vary as a function of working memory capacity, therefore we hypothesized that both small-worldness and modularity would show age-related declines. We found that both small-worldness and modularity were negatively correlated with increasing age but that this decline was relatively slow.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Onoda K,Yamaguchi Sdoi
10.1016/j.neulet.2013.10.023subject
Has Abstractpub_date
2013-11-27 00:00:00pages
104-8eissn
0304-3940issn
1872-7972pii
S0304-3940(13)00927-0journal_volume
556pub_type
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