Correlation of increased hippocampal Sumo3 with spatial learning ability in old C57BL/6 mice.

abstract：:Schisandra chinensis is commonly used for food and as a traditional remedy for the treatment of neuronal disorders. However, it is unclear which component of S. chinensis is responsible for its neuropharmacological effects. To answer this question, we isolated α-iso-cubebene, a dibenzocyclooctadiene lignin, from S. ch...

journal_title：Neuroscience letters

authors： Park SY,Park SJ,Park NJ,Joo WH,Lee SJ,Choi YW

更新日期：2013-10-25 00:00:00

abstract：:Integrin-associated protein (IAP) is normally localized to the synapse rich plexiform layers of the mammalian retina. In other neuronal systems, IAP and its ligand, P84, have been implicated in synaptic function. Previously, an abnormal distribution of P84 was noted in the IAP-null retina. To examine the potential rol...

journal_title：Neuroscience letters

authors： Ball SL,Lindberg FP,Lagenaur CF,Peachey NS

更新日期：2001-02-02 00:00:00

abstract：:Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) may involve many target organs with relevant variability among affected individuals. We performed a multi-organ assessment tapping nervous system, skeletal muscle and cardiovascular system in thirty-nine individuals be...

journal_title：Neuroscience letters

authors： Ragno M,Pianese L,Cacchiò G,Manca A,Scarcella M,Silvestri S,Di Marzio F,Caiazzo AR,Silvaggio F,Tasca G,Mirabella M,Trojano L

更新日期：2012-01-06 00:00:00

abstract：:Alpha-synuclein (α-SYN) is found in peripheral autonomic neuronal network apart from brain in Parkinson's disease (PD). Nitrated α-SYN is an undesirable modification associated with oxidative and nitrative damage and has been found extensively in brain, gastrointestinal(GI) tract and blood cells in PD. We aim to inves...

journal_title：Neuroscience letters

authors： Ma LY,Gao LY,Li X,Ma HZ,Feng T

更新日期：2019-06-21 00:00:00

abstract：:Ifenprodil, a non-competitive NMDA-receptor antagonist, has been shown to exhibit marked cytoprotective activities in animal models for focal ischemia and Parkinson's disease. To test the hypothesis that the cytoprotective effect is due to the release of neurotrophic factors (NTFs), we examined the effects of ifenprod...

journal_title：Neuroscience letters

authors： Toyomoto M,Inoue S,Ohta K,Kuno S,Ohta M,Hayashi K,Ikeda K

更新日期：2005-05-13 00:00:00

abstract：:An increase in the number of cells undergoing apoptosis was observed in the cingulate sulcus of newborn piglets 48 h after a global hypoxic-ischaemic insult. Apoptotic death was identified morphologically (by light and electron microscopy) and by DNA fragmentation, detected by in situ end labelling. The number of apop...

journal_title：Neuroscience letters

authors： Mehmet H,Yue X,Squier MV,Lorek A,Cady E,Penrice J,Sarraf C,Wylezinska M,Kirkbride V,Cooper C

更新日期：1994-11-07 00:00:00

abstract：:Olprinone, an inhibitor of cyclic nucleotide phosphodiesterase III, inhibited an increase in intracellular Ca(2+) concentrations for acutely dissociated rat hippocampal pyramidal neurons induced by extracellular high K(+) (35 mM) depolarization. Olprinone (100 microM) significantly reduced spontaneous glutamate releas...

journal_title：Neuroscience letters

authors： Fujikawa H,Kanno T,Nagata T,Nishizaki T

更新日期：2008-12-26 00:00:00

abstract：:The administration of DN-1417, a synthetic derivative of TRH with more potent central action, significantly reduced specific [3H]GABA binding in the cerebellum, whereas [3H]GABA binding in the cerebral cortex was not changed. Scatchard analysis showed that the decreased [3H]GABA binding in the cerebellum was due to de...

journal_title：Neuroscience letters

authors： Tatsuoka Y,Kato Y,Imura H

更新日期：1983-12-02 00:00:00

abstract：:The neural mechanisms of low back pain (LBP) are still enigmatic. Presently, low back muscles are being discussed as an important source of LBP. Here, the neuroanatomical pathway of the nociceptive information from the caudal multifidus muscle (MF) was studied. True blue was injected into the MF at the level L5 to vis...

journal_title：Neuroscience letters

authors： Taguchi T,John V,Hoheisel U,Mense S

更新日期：2007-10-29 00:00:00

abstract：:In this study, we investigated the role of nitric oxide (NO) in neuronal cell death in the lipopolysaccharide (LPS)-treated rat hippocampal slice culture. Neuronal cell death was induced after a LPS treatment in a rat hippocampal slice. The region and time course of the cell death caused by LPS were different from tho...

journal_title：Neuroscience letters

authors： Lee P,Son D,Lee J,Kim YS,Kim H,Kim SY

更新日期：2003-09-25 00:00:00

abstract：:Oxytocin (OT) modulation of synaptic transmission between olfactory bulb neurones has been implicated in the induction of maternal behaviour, but the mechanism of action is unknown. We examined the action of OT on gamma-aminobutyric acid(A) (GABA(A)) receptor-mediated spontaneous inhibitory postsynaptic currents (sIPS...

journal_title：Neuroscience letters

authors： Osako Y,Otsuka T,Taniguchi M,Oka T,Kaba H

更新日期：2000-07-28 00:00:00

abstract：:Typical histopathological findings of multiple system atrophy (MSA) have been observed in motor related cortices, in addition to the common areas of the striatum, substantia nigra, olivopontocerebellar pathways, the intermediolateral cell columns of the spinal cord, and the cerebellum. The purpose of this study is to ...

journal_title：Neuroscience letters

authors： You H,Wang J,Wang H,Zang YF,Zheng FL,Meng CL,Feng F

更新日期：2011-09-08 00:00:00

abstract：:Seizures are relatively common in the first weeks of life and can have lasting effects on brain development due to glutamate excitotoxicity. The excitatory amino acid transporter 2 (EAAT2) is responsible for the majority of glutamate uptake in the brain and mice with this gene deleted die from seizures. Therefore, we ...

journal_title：Neuroscience letters

authors： Lauriat TL,Schmeidler J,McInnes LA

更新日期：2007-01-22 00:00:00

abstract：:Single electrode voltage-clamp recording from CA3 neurons in guinea pig hippocampal slices was applied to study effects of a new GABAB antagonist, CGP 55845A, on (-)baclofen (IBac)- or gamma-aminobutyric acid (IGABA)-induced potassium (K)-currents and on inhibitory postsynaptic K-currents (K-IPSCs) recorded in the pre...

journal_title：Neuroscience letters

authors： Jarolimek W,Demmelhuber J,Bijak M,Misgeld U

更新日期：1993-05-14 00:00:00

abstract：:Painful vincristine (VCR) neuropathy is a frequent and dose-limiting problem in cancer treatment. Here, we investigated how pain behavior is modulated in mice lacking the serotonin transporter (5-HTT-/- mice) after inducing neuropathy by intraperitoneal injections of VCR. We used standard tests for evoked pain, high p...

journal_title：Neuroscience letters

authors： Hansen N,Uçeyler N,Palm F,Zelenka M,Biko L,Lesch KP,Gerlach M,Sommer C

更新日期：2011-05-16 00:00:00

abstract：:Copulation was induced in pairs of Aplysia fasciata by adding to the environment a homogenate of the distal portion of the large hermaphroditic duct. Similar effects were not observed in response to an abdominal ganglion homogenate. The data suggest that the duct may secrete a pheromone initiating copulation in Aplysi...

journal_title：Neuroscience letters

authors： Susswein AJ,Benny M

更新日期：1985-09-06 00:00:00

abstract：:Distributions of 25 motor axons to 60 intrafusal muscle fibers of 10 poles of monkey spindle were reconstructed from serial 1 micron thick transverse sections of lumbrical muscles. About 44% of motor axons co-innervated two or more types of intrafusal fiber. The (dynamic) bag1 fiber shared motor innervation with the (...

journal_title：Neuroscience letters

authors： Kucera J

更新日期：1985-01-07 00:00:00

abstract：:Vlgr1 (very large G-protein coupled receptor 1) knockout mice against hybrid backgrounds of the 129/Ola and C57BL/6 mouse strains show hearing deficit and high susceptibility to audiogenic seizures. The present study examined how hearing impairment and susceptibility to audiogenic seizures in Vlgr1-deficient mice chan...

journal_title：Neuroscience letters

authors： Yagi H,Noguchi Y,Kitamura K,Sato M

更新日期：2009-09-18 00:00:00

abstract：:Morphine analgesia measured by the tail withdrawal test was examined in rats that were either restrained or left free during testing. It was found that restraint potentiated morphine analgesia and decreased the latency of the peak analgesic effect. Methysergide, a serotonin antagonist, and valine, which prevents the i...

journal_title：Neuroscience letters

authors： Kelly SJ,Franklin KB

更新日期：1984-02-24 00:00:00

abstract：:Dysregulated brain glucose metabolism and lactate accumulation are seen following traumatic brain injury (TBI). The underlying molecular mechanism is poorly understood. Pyruvate dehydrogenase (PDH), the rate-limiting enzyme coupling cytosolic glycolysis to mitochondrial citric acid cycle, plays a critical role in main...

journal_title：Neuroscience letters

authors： Xing G,Ren M,Watson WD,O'Neill JT,Verma A

更新日期：2009-04-17 00:00:00

abstract：:For 76 healthy subjects, two non-linear measures, capturing the dynamical properties of the system orbiting within the attractor (i.e. Kolmogorov entropy, K2 and principal Lyapunov exponent, L1), were calculated from EEG segments, corresponding to different states of brain activity, induced by emotionally valenced (i....

journal_title：Neuroscience letters

authors： Aftanas LI,Lotova NV,Koshkarov VI,Pokrovskaja VL,Popov SA,Makhnev VP

更新日期：1997-04-18 00:00:00

abstract：:Sepsis-associated encephalopathy (SAE) has significant impact on the neurocognitive outcome of sepsis survivors. This study was conducted to analyze the amino-terminal propeptide of the C-type natriuretic peptide (NT-proCNP) as a biomarker for SAE in comparison to neuron-specific enolase (NSE) and S100B protein. Cereb...

journal_title：Neuroscience letters

authors： Ehler J,Saller T,Wittstock M,Rommer PS,Chappell D,Zwissler B,Grossmann A,Richter G,Reuter DA,Nöldge-Schomburg G,Sauer M

更新日期：2019-01-23 00:00:00

abstract：:Increasing evidence suggests a relation between vascular disorders and late-onset Alzheimer's disease (AD). We performed an association analysis of low-density lipoprotein receptor-related protein (LRP), lipoprotein lipase (LPL), and angiotensin converting enzyme (ACE) genes, known to be involved in vascular disorders...

journal_title：Neuroscience letters

authors： Myllykangas L,Polvikoski T,Sulkava R,Verkkoniemi A,Tienari P,Niinistö L,Kontula K,Hardy J,Haltia M,Pérez-Tur J

更新日期：2000-10-13 00:00:00

abstract：:Bilateral injections of the GABA(A) agonist muscimol into the lateral parabrachial nucleus (LPBN) disrupt satiety and induce strong ingestion of water and 0.3M NaCl in fluid-replete rats by mechanisms not completely clear. In the present study, we investigated the effects of the blockade of central muscarinic choliner...

journal_title：Neuroscience letters

authors： Asnar DS,Roncari CF,De Luca LA Jr,de Paula PM,Colombari DS,Menani JV

更新日期：2013-02-08 00:00:00

abstract：:We investigated the cortico-muscular coherence in a patient with posturally induced cortically originating negative myoclonus. We recorded simultaneously 50 channels EEG and EMG from quadriceps and biceps femoris muscles of the left upper leg. Three experimental conditions were investigated with the patient in a seate...

journal_title：Neuroscience letters

authors： Kristeva R,Popa T,Chakarov V,Hummel S

更新日期：2004-08-19 00:00:00

abstract：:The ability in vivo of the muscarinic agonist, pilocarpine, to increase phosphoinositol (PI) hydrolysis in lithium pretreated rats was investigated by measuring the accumulation of [(3)H]inositol phosphates (IP). As expected, 20 mg/kg s.c. pilocarpine, a muscarinic agonist, increased PI hydrolysis in the striatum, fro...

journal_title：Neuroscience letters

authors： Johnson MP,Kelly GM,Chamberlain M

更新日期：2000-05-05 00:00:00

abstract：:The projections of neurons, in and around the A1 noradrenergic cell group of the caudal ventrolateral medulla (VLM), to nucleus of the solitary tract (NTS) were studied in the cat using the anterograde transport of Phaseolus vulgaris leucoagglutinin (PHA-L). PHA-L was micro-iontophoresed into the region of the A1 nora...

journal_title：Neuroscience letters

authors： Roder S,Ciriello J

更新日期：1992-01-06 00:00:00

abstract：:Conduction velocities of antidromically evoked impulses along the goldfish Mauthner axon were found to be inversely correlated with body length. To test the hypothesis that such a relation is accompanied by a reduction in axonal diameter with increasing fish size, Mauthner axon diameters were measured. A parabolic rel...

journal_title：Neuroscience letters

authors： Funch PG,Kinsman SL,Faber DS,Koenig E,Zottoli SJ

更新日期：1981-12-11 00:00:00

abstract：:This study assessed whether the use of an "anchor system" benefited older adults who performed a tandem walking task. Additionally, we tested the effects of practice with the anchor system during walking on trunk stability, in the frontal plane, of older adults. Forty-four older adults were randomly assigned to three ...

journal_title：Neuroscience letters

authors： Costa AA,Manciopi PA,Mauerberg-deCastro E,Moraes R

更新日期：2015-11-16 00:00:00

abstract：:Repetitive transcranial magnetic stimulation (rTMS) is a promising method for use in the clinical field, as it can induce modulation of cortical excitability. Generally, rTMS inhibits the motor cortex when delivered at less than 1 Hz. However, it has been indicated that a facilitative effect is induced by 1 Hz rTMS, d...

journal_title：Neuroscience letters

authors： Nojima K,Iramina K

更新日期：2018-01-18 00:00:00