Liver adenomatosis. An entity distinct from liver adenoma?

Abstract:

:From 1979 to 1984, we followed the cases of 3 men (aged 13, 31, and 75 yr) and 2 women (aged 38 and 45 yr who had never used oral contraceptives) suffering from liver adenomatosis, an uncommon lesion consisting of numerous benign adenomas in an otherwise normal hepatic parenchyma. During the same period, we observed 20 cases of liver adenoma (one tumor in 18 patients and two tumors in 2 patients). From these cases and the review of previously reported cases of liver adenomatosis and series of liver adenoma, the following distinctive characteristics of these two benign conditions of the liver can be outlined: liver adenomatosis affects men and women, whereas liver adenoma predominantly affects women; liver adenomatosis is unrelated, whereas liver adenoma is closely related, to oral contraceptive use; increases in serum alkaline phosphatase and gamma-glutamyl transpeptidase are common in liver adenomatosis, but are uncommon in liver adenoma.

journal_name

Gastroenterology

journal_title

Gastroenterology

authors

Flejou JF,Barge J,Menu Y,Degott C,Bismuth H,Potet F,Benhamou JP

subject

Has Abstract

pub_date

1985-11-01 00:00:00

pages

1132-8

issue

5

eissn

0016-5085

issn

1528-0012

pii

0016-5085(85)90220-3

journal_volume

89

pub_type

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