Treatment of hepatocellular carcinoma by percutaneous tumor ablation methods: Ethanol injection therapy and radiofrequency ablation.

Abstract:

:In Japan, approximately 30,000 patients died of hepatocellular carcinoma (HCC) in 2003. Ten percent had hepatitis B virus infection and 80% had hepatitis C virus (HCV) infection, indicating that viral hepatitis accounted for >90% of cases of HCC. In comparison, only 3% (1.5%, hepatitis B virus; 1.5%, HCV) of the general population is infected with these viruses. We treated 1238 patients between 1992 and the end of 2003 by means of percutaneous tumor ablation (PTA): 524 patients, by percutaneous ethanol injection therapy (PEIT); 85 patients, by percutaneous microwave coagulation therapy; and 629 patients, by radiofrequency ablation (RFA). Three-, 5-, 7-, and 10-year survival rates of the 1238 patients were 69%, 50%, 34%, and 19%, respectively. When limited to tumors

journal_name

Gastroenterology

journal_title

Gastroenterology

authors

Omata M,Tateishi R,Yoshida H,Shiina S

doi

10.1053/j.gastro.2004.09.030

keywords:

subject

Has Abstract

pub_date

2004-11-01 00:00:00

pages

S159-66

issue

5 Suppl 1

eissn

0016-5085

issn

1528-0012

pii

S0016508504016099

journal_volume

127

pub_type

杂志文章
  • Prognostic value of arterial pressure, endogenous vasoactive systems, and renal function in cirrhotic patients admitted to the hospital for the treatment of ascites.

    abstract::To identify prognostic factors in cirrhotic patients admitted to the hospital for the treatment of an episode of ascites, a survival analysis was performed in a series of 139 patients hospitalized in our Unit between 1980 and 1985. Mean follow-up was 12.8 +/- 14.2 mo (mean +/- SD). A total of 38 variables based on his...

    journal_title:Gastroenterology

    pub_type: 杂志文章

    doi:10.1016/0016-5085(88)90441-6

    authors: Llach J,Ginès P,Arroyo V,Rimola A,Titó L,Badalamenti S,Jiménez W,Gaya J,Rivera F,Rodés J

    更新日期:1988-02-01 00:00:00

  • Gastric mucosal alpha(4)beta(7)-integrin-positive CD4 T lymphocytes and immune protection against helicobacter infection in mice.

    abstract:BACKGROUND & AIMS:The integrin alpha(4)beta(7) mediates homing of effector/memory lymphocytes to the intestine and the mucosa-associated lymphoid tissue. This study examined the ability of alpha(4)beta(7)(hi) CD4(+) T lymphocytes to home to the stomach and their role in immunization-mediated protection against Helicoba...

    journal_title:Gastroenterology

    pub_type: 杂志文章

    doi:10.1053/gast.2000.8548

    authors: Michetti M,Kelly CP,Kraehenbuhl JP,Bouzourene H,Michetti P

    更新日期:2000-07-01 00:00:00

  • Role of gastrin-releasing peptide in the neural control of pepsinogen secretion from the pig stomach.

    abstract::A new experimental model, the isolated perfused antrectomized pig stomach with intact vagal innervation, was shown to produce pepsinogen and gastric acid upon electrical stimulation of the vagus nerves and by intravascular administration of carbachol (from a basal value of 111 +/- 24 units of pepsin per minute and 0.0...

    journal_title:Gastroenterology

    pub_type: 杂志文章

    doi:10.1016/0016-5085(88)90353-8

    authors: Skak-Nielsen T,Holst JJ,Nielsen OV

    更新日期:1988-11-01 00:00:00

  • Comparison of human jejunal and ileal fat absorption by electron microscopy.

    abstract::Morphologic and physiologic experiments in rodents have demonstrated differences between jejunal and ileal fat absorption. Compared with the rat jejunum, absorbed lipid particles within rat ileal absorptive cells are larger and exit at a slower rate. To evaluate the relevance of these observations to humans, we studie...

    journal_title:Gastroenterology

    pub_type: 杂志文章

    doi:10.1016/0016-5085(88)90676-2

    authors: Surawicz CM,Levine DS,Saunders DR,Rubin CE

    更新日期:1988-06-01 00:00:00

  • Analysis of Ki-ras codon 12 mutations in the duodenal juice of patients with pancreatic cancer.

    abstract:BACKGROUND & AIMS:Point mutations of the Ki-ras gene at codon 12 have been frequently identified in pure pancreatic juice of patients with pancreatic cancer in studies examining pancreatic cancer tissues. The aim of this study was to examine mutations of the Ki-ras codon 12 in the duodenal juice collected from patients...

    journal_title:Gastroenterology

    pub_type: 杂志文章

    doi:10.1053/gast.1996.v110.pm8536860

    authors: Iguchi H,Sugano K,Fukayama N,Ohkura H,Sadamoto K,Ohkoshi K,Seo Y,Tomoda H,Funakoshi A,Wakasugi H

    更新日期:1996-01-01 00:00:00

  • The effect of ischemic villus cell damage on crypt cell proliferation in the small intestine: evidence for a feedback control mechanism.

    abstract::In recent years the hypothesis that the number of villus cells regulates crypt cell proliferation in the epithelium of the small intestine has been brought forward by a number of investigators. To test this hypothesis, the villus cell population was reduced by clamping the superior mesenteric artery and vein in rats f...

    journal_title:Gastroenterology

    pub_type: 杂志文章

    doi:

    authors: Rijke RP,Hanson WR,Plaisier HM,Osborne JW

    更新日期:1976-11-01 00:00:00

  • Hepatic toxicity in the rhesus monkey treated with chenodeoxycholic acid for 6 months: biochemical and ultrastructural studies.

    abstract::The long term administration of chenodeoxycholic acid in man has to be regarded with caution because chenodeoxycholic acid has caused liver damage in various species of animals, including primates. To study the effect of three doses of chenodeoxycholic acid (10, 40, and 100 mg per kg per day) on hepatic function and m...

    journal_title:Gastroenterology

    pub_type: 杂志文章

    doi:

    authors: Dyrszka H,Salen G,Zaki FG,Chen T,Mosbach EH

    更新日期:1976-01-01 00:00:00

  • Admission volume determines outcome for patients with acute pancreatitis.

    abstract:BACKGROUND & AIMS:There is controversy over the optimal management strategy for patients with acute pancreatitis (AP). Studies have shown a hospital volume benefit for in-hospital mortality after surgery, and we examined whether a similar mortality benefit exists for patients admitted with AP. METHODS:Using the Nation...

    journal_title:Gastroenterology

    pub_type: 杂志文章

    doi:10.1053/j.gastro.2009.08.056

    authors: Singla A,Simons J,Li Y,Csikesz NG,Ng SC,Tseng JF,Shah SA

    更新日期:2009-12-01 00:00:00

  • Adenocarcinomas of the colon and rectum in persons under 40 years old. A population-based study.

    abstract::Data collected by nine population-based tumor registries participating in the Surveillance, Epidemiology, and End Results Program of the National Cancer Institute were analyzed to characterize the epidemiology of noncarcinoid adenocarcinomas of the colon and rectum in young adults. Tumors diagnosed in persons under 40...

    journal_title:Gastroenterology

    pub_type: 杂志文章

    doi:10.1016/0016-5085(91)90279-t

    authors: Griffin PM,Liff JM,Greenberg RS,Clark WS

    更新日期:1991-04-01 00:00:00

  • Transient mosaic patterns of morphological and functional differentiation in the Caco-2 cell line.

    abstract::To gain further insight on the mosaic expression of specific functional intestinal markers (such as sucrase-isomaltase) in postconfluent Caco-2 cells, a human colon cancer cell line unique in its property to differentiate in vitro into a mature enterocyte-like cell type, a comparative study was undertaken to examine t...

    journal_title:Gastroenterology

    pub_type: 杂志文章

    doi:10.1016/0016-5085(92)90829-n

    authors: Vachon PH,Beaulieu JF

    更新日期:1992-08-01 00:00:00

  • Increased Risk of Colorectal Cancer in Individuals With a History of Serrated Polyps.

    abstract:BACKGROUND AND AIMS:Serrated polyp (SPs) are precursors to 20% to 30% of cases of colorectal tumors, but patients' long-term risk after removal of SPs is poorly understood. We investigated the risk of colorectal cancer (CRC) in individuals with a history of SPs. METHODS:We performed a retrospective cohort study of Kai...

    journal_title:Gastroenterology

    pub_type: 杂志文章

    doi:10.1053/j.gastro.2020.04.004

    authors: Li D,Liu L,Fevrier HB,Alexeeff SE,Doherty AR,Raju M,Amsden LB,Lee JK,Levin TR,Corley DA,Herrinton LJ

    更新日期:2020-08-01 00:00:00

  • Roles of iron and HFE mutations on severity and response to therapy during retreatment of advanced chronic hepatitis C.

    abstract:BACKGROUND & AIMS:Iron overload may cause or contribute to hepatic injury and fibrosis. Mutations in the HFE gene may influence development or progression of chronic liver disease by increasing iron stores or modulating immune responses. The aim of this work was to assess the influence of HFE mutations and serum and he...

    journal_title:Gastroenterology

    pub_type: 临床试验,杂志文章

    doi:10.1053/j.gastro.2006.08.036

    authors: Bonkovsky HL,Naishadham D,Lambrecht RW,Chung RT,Hoefs JC,Nash SR,Rogers TE,Banner BF,Sterling RK,Donovan JA,Fontana RJ,Di Bisceglie AM,Ghany MG,Morishima C,HALT-C Trial Group.

    更新日期:2006-11-01 00:00:00

  • Hepatic vasculature: a conceptual review.

    abstract::The hepatic circulation is reviewed with emphasis on the role of hepatic blood vessels in hepatic and homeostatic functions. Contrasts are made with resistance, capacitance, and fluid exchange functions in other better known vascular beds. Hemodynamic changes that produce shifts in fluid exchange in other tissues are ...

    journal_title:Gastroenterology

    pub_type: 杂志文章,评审

    doi:

    authors: Lautt WW

    更新日期:1977-11-01 00:00:00

  • Increased risk of functional gastrointestinal sequelae after Clostridium difficile infection among active duty United States military personnel (1998-2010).

    abstract:BACKGROUND & AIMS:Some acute enteric infections are associated with the development of functional gastrointestinal disorders, most commonly irritable bowel syndrome but also other functional and organic gastrointestinal sequelae. Clostridium difficile infection has increased in incidence and severity, however, few stud...

    journal_title:Gastroenterology

    pub_type: 杂志文章

    doi:10.1053/j.gastro.2015.07.059

    authors: Gutiérrez RL,Riddle MS,Porter CK

    更新日期:2015-11-01 00:00:00

  • Incidence and recurrence rates of colorectal adenomas: a prospective study.

    abstract:BACKGROUND/AIMS:The frequency of colorectal adenomas, the precursor lesions for most cases of colorectal carcinoma, has been generally measured as prevalence rates of adenomas at autopsy or colonoscopy. The aim of this study was to estimate the incidence rate of adenomas and compare it with the adenoma recurrence rate....

    journal_title:Gastroenterology

    pub_type: 杂志文章

    doi:10.1016/0016-5085(95)90066-7

    authors: Neugut AI,Jacobson JS,Ahsan H,Santos J,Garbowski GC,Forde KA,Treat MR,Waye J

    更新日期:1995-02-01 00:00:00

  • Rats with gastritis have increased sensitivity to the gastrin stimulatory effects of luminal ammonia.

    abstract:BACKGROUND & AIMS:Persons infected with Helicobacter pylori show an enhanced meal-stimulated gastrin release compared with uninfected controls. The aim of this study was to determine in animal models whether this gastrin release could be related to chronic gastric inflammation, elevated luminal ammonia level, or a comb...

    journal_title:Gastroenterology

    pub_type: 杂志文章

    doi:10.1053/gast.1996.v110.pm8608890

    authors: Dial EJ,Hall LR,Romero JJ,Lichtenberger LM

    更新日期:1996-03-01 00:00:00

  • Ventromedial hypothalamic lesions increase gastrointestinal DNA synthesis through vagus nerve in rats.

    abstract:BACKGROUND:It was recently reported that ventromedial hypothalamic (VMH) lesions produced an increase in gastrointestinal DNA content in rats. In the present study, the mechanism of this alteration was examined. METHODS:The DNA content and synthesis after VMH lesioning in rat gastrointestinal tracts were determined. ...

    journal_title:Gastroenterology

    pub_type: 杂志文章

    doi:10.1016/0016-5085(93)90416-a

    authors: Kiba T,Tanaka K,Endo O,Inoue S

    更新日期:1993-02-01 00:00:00

  • Macrophage migration inhibitory factor promotes intestinal tumorigenesis.

    abstract:BACKGROUND & AIMS:The cytokine macrophage migration inhibitory factor (MIF) is expressed throughout the human gastrointestinal tract. Recently, protumorigenic activity of MIF has been described in several cancer models. Therefore, we investigated the expression and function of MIF during the early stages of intestinal ...

    journal_title:Gastroenterology

    pub_type: 杂志文章

    doi:10.1053/j.gastro.2005.07.061

    authors: Wilson JM,Coletta PL,Cuthbert RJ,Scott N,MacLennan K,Hawcroft G,Leng L,Lubetsky JB,Jin KK,Lolis E,Medina F,Brieva JA,Poulsom R,Markham AF,Bucala R,Hull MA

    更新日期:2005-11-01 00:00:00

  • Liver disease in vineyard sprayers.

    abstract::Liver disease with inclusions of copper was recognized among 30 rural workers with "vineyard sprayer's lung." The pathological findings were varied: focal or diffuse swelling and proliferation of Kupffer cells; histiocytic and sarcoid-like granulomata; fibrosis of variable degree in the perisinusoidal, portal, and sub...

    journal_title:Gastroenterology

    pub_type: 杂志文章

    doi:

    authors: Pimentel JC,Menezes AP

    更新日期:1977-02-01 00:00:00

  • Artificial neural network as a predictive instrument in patients with acute nonvariceal upper gastrointestinal hemorrhage.

    abstract:BACKGROUND & AIMS:Triage of patients with acute upper gastrointestinal hemorrhage (UGIH) has traditionally required urgent upper endoscopy. The aim of this study is to evaluate the use of artificial neural network for nonendoscopic triage. METHODS:A cohort of 387 patients was used to train (n = 194) and internally val...

    journal_title:Gastroenterology

    pub_type: 杂志文章

    doi:10.1053/j.gastro.2007.10.037

    authors: Das A,Ben-Menachem T,Farooq FT,Cooper GS,Chak A,Sivak MV Jr,Wong RC

    更新日期:2008-01-01 00:00:00

  • Expression of HLA-linked hemochromatosis in subjects homozygous or heterozygous for the C282Y mutation.

    abstract:BACKGROUND & AIMS:In the absence of a genetic test, diagnostic criteria for hereditary hemochromatosis have been imprecise. The identification of the HFE gene and the C282Y mutation allow definition of expression of this disease and reassessment of diagnostic criteria. The aim of this study was to analyze the concordan...

    journal_title:Gastroenterology

    pub_type: 杂志文章

    doi:10.1016/s0016-5085(98)70320-8

    authors: Crawford DH,Jazwinska EC,Cullen LM,Powell LW

    更新日期:1998-05-01 00:00:00

  • Reg IV regulates normal intestinal and colorectal cancer cell susceptibility to radiation-induced apoptosis.

    abstract:BACKGROUND & AIMS:Regenerating (Reg) gene IV is predominantly expressed in gastrointestinal cells and highly up-regulated in many gastrointestinal malignancies, including colorectal cancer (CRC). Human CRC cells expressing higher levels of Reg IV gene and its protein product (Reg IV) are resistant to conventional thera...

    journal_title:Gastroenterology

    pub_type: 杂志文章

    doi:10.1053/j.gastro.2009.10.050

    authors: Bishnupuri KS,Luo Q,Sainathan SK,Kikuchi K,Sureban SM,Sabarinathan M,Gross JH,Aden K,May R,Houchen CW,Anant S,Dieckgraefe BK

    更新日期:2010-02-01 00:00:00

  • Early diagnosis of pancreatic infection by computed tomography-guided aspiration.

    abstract::We performed 92 computed tomography-guided percutaneous needle aspirations of pancreatic inflammatory masses in 60 patients suspected of harboring pancreatic infection. Thirty-six patients (60%) were found by Gram stain and culture to have a total of 41 separate episodes of pancreatic infection. Among 42 aspirates jud...

    journal_title:Gastroenterology

    pub_type: 杂志文章

    doi:10.1016/0016-5085(87)90261-7

    authors: Gerzof SG,Banks PA,Robbins AH,Johnson WC,Spechler SJ,Wetzner SM,Snider JM,Langevin RE,Jay ME

    更新日期:1987-12-01 00:00:00

  • Impaired viscerosomatic reflexes and abdominal-wall dystony associated with bloating.

    abstract:BACKGROUND & AIMS:Abdominal bloating is a frequent complaint in irritable bowel syndrome (IBS), but its underlying mechanism remains uncertain. Our aim was to determine whether the abdominal wall, specifically its adaptation to intra-abdominal volumes, plays a role. METHODS:In 12 patients complaining of abdominal bloa...

    journal_title:Gastroenterology

    pub_type: 杂志文章

    doi:10.1053/j.gastro.2005.12.036

    authors: Tremolaterra F,Villoria A,Azpiroz F,Serra J,Aguadé S,Malagelada JR

    更新日期:2006-04-01 00:00:00

  • Cryptosporidium: cellular localization, structural analysis of absorptive cell-parasite membrane-membrane interactions in guinea pigs, and suggestion of protozoan transport by M cells.

    abstract::In ilea of spontaneously infested guinea pigs, we examined the interface between the plasma membranes of cryptosporidia and absorptive cells using thin section and freeze fracture techniques. Initially, cryptosporidia invaginate microvilli, and the resulting redundant folds of membrane envelop the protozoan, thereby i...

    journal_title:Gastroenterology

    pub_type: 杂志文章

    doi:10.1016/0016-5085(86)91112-1

    authors: Marcial MA,Madara JL

    更新日期:1986-03-01 00:00:00

  • Hyponatremia and arginine vasopressin secretion in patients with refractory hepatic ascites undergoing peritoneovenous shunting.

    abstract::Seven patients with persistent hyponatremia but normal or elevated serum arginine vasopressin levels and refractory ascites undergoing peritoneovenous shunting were studied in a Metabolic Unit on a 20 mEq sodium 1200 ml fluid-restricted diet to elucidate the mechanism of this response. The intravascular volume expansi...

    journal_title:Gastroenterology

    pub_type: 杂志文章

    doi:

    authors: Reznick RK,Langer B,Taylor BR,Seif S,Blendis LM

    更新日期:1983-04-01 00:00:00

  • Wilson's disease in patients presenting with liver disease: a diagnostic challenge.

    abstract:BACKGROUND & AIMS:In patients with Wilson's disease presenting with liver involvement, the correct diagnosis is often missed or delayed. The aim of this study was to find an algorithm for diagnosis of this difficult patient group. METHODS:Clinical and laboratory findings of 55 patients with Wilson's disease were evalu...

    journal_title:Gastroenterology

    pub_type: 杂志文章

    doi:10.1016/s0016-5085(97)70097-0

    authors: Steindl P,Ferenci P,Dienes HP,Grimm G,Pabinger I,Madl C,Maier-Dobersberger T,Herneth A,Dragosics B,Meryn S,Knoflach P,Granditsch G,Gangl A

    更新日期:1997-07-01 00:00:00

  • High-dose oral erythromycin decreased the incidence of parenteral nutrition-associated cholestasis in preterm infants.

    abstract:BACKGROUND & AIMS:Feeding intolerance because of functional gastrointestinal dysmotility and parenteral nutrition-associated cholestasis (PNAC) are common problems in preterm, very-low-birth-weight (VLBW) infants. This double-blind, randomized, placebo-controlled study aimed to assess the effectiveness of "high-dose" o...

    journal_title:Gastroenterology

    pub_type: 杂志文章,随机对照试验

    doi:10.1053/j.gastro.2007.03.043

    authors: Ng PC,Lee CH,Wong SP,Lam HS,Liu FY,So KW,Lee CY,Fok TF

    更新日期:2007-05-01 00:00:00

  • The motor response to intestinal resection: motor activity in the canine small intestine following distal resection.

    abstract:BACKGROUND:The mucosal response to intestinal resection has been extensively studied; little is known of the motor response. Our aim was to evaluate motility in the intestinal remnant following distal resection. METHODS:Motor activity, duodenocecal transit, nutrition, and absorption were studied over a 3-month period ...

    journal_title:Gastroenterology

    pub_type: 杂志文章

    doi:10.1016/0016-5085(93)90897-l

    authors: Quigley EM,Thompson JS

    更新日期:1993-09-01 00:00:00

  • Ultrastructural immunocytochemical localization of the asialoglycoprotein receptor in rat hepatocytes.

    abstract::The asialoglycoprotein receptor is present on the plasma membrane of rat hepatocytes and mediates the endocytosis of exogenous asialoglycoproteins. The intracellular locations of the receptor are incompletely defined, and whether the receptor is present on the canalicular membrane is controversial. To investigate thes...

    journal_title:Gastroenterology

    pub_type: 杂志文章

    doi:

    authors: Mizuno M,Brown WR,Vierling JM

    更新日期:1984-10-01 00:00:00