Cyanobacterium producing cylindrospermopsin cause histopathological changes at environmentally relevant concentrations in subchronically exposed tilapia (Oreochromis niloticus).

abstract：:Three methods of algal assays--the standard assay, microassay, and the proposed fluorescence assay--are compared from the point of view of reliability of EC50 detection, the minimum required time for the detection, sensitivity of individual measurement, i.e. at which cell density the particular assay can be used for E...

journal_title：Environmental toxicology

authors： Kvíderová J

更新日期：2010-12-01 00:00:00

abstract：:In the present study, responses of the Chinese brown frog (Rana chensinensis) to exposure to di-2-ethylhexyl phthalate (DEHP), a common plasticizer, during the larval period were characterized. The effects of DEHP on metamorphosis rate, thyroid hormone, thyroid histology and the expression of genes involved in the ste...

journal_title：Environmental toxicology

authors： Zhang Y,Li X,Gao J,Wang H

更新日期：2018-01-01 00:00:00

abstract：:In May of 2006 we suddenly began to observe neural tube defects (NTDs) in embryos of untreated control mice. We hypothesized the mice were being exposed unknowingly to a teratogenic agent and investigated the cause. Our results suggested that NTDs were not resulting from bedding material, feed, strain, or source of th...

journal_title：Environmental toxicology

authors： Mallela MK,Werre SR,Hrubec TC

更新日期：2011-11-01 00:00:00

abstract：:Multi-walled carbon nanotubes (MWCNTs) have many applications in industry and used as additives in polymers, catalysts, anodes in lithium-battery and drug delivery. There is little information about MWCNTs' (210 nm) genotoxic potential on juvenile freshwater fish Channa punctatus. Therefore, in this study, we have det...

journal_title：Environmental toxicology

authors： Ali D,Falodah FA,Almutairi B,Alkahtani S,Alarifi S

更新日期：2020-03-01 00:00:00

abstract：:Ouabain, a cardiotonic steroid, was used for the treatment of heart failure and atrial fibrillation and induces cancer cell apoptosis in many human cancer cells including human leukemia cells. However, there are no reports to show the effects on immune responses in a leukemia mouse model. In this study, WEHI-3 cell ge...

journal_title：Environmental toxicology

authors： Shih YL,Shang HS,Chen YL,Hsueh SC,Chou HM,Lu HF,Lee MZ,Hou HT,Chuang YY,Lee MH,Chen KW,Chung JG

更新日期：2019-05-01 00:00:00

abstract：:The bioaccumulation of the triazine herbicides terbutryn and terbuthylazine in rainbow trout was investigated at water temperatures of 4 degrees C, 10 degrees C, and 17 degrees C. The synergetic effect of water temperature and herbicide on fish liver detoxification metabolism was also studied by measuring liver ethoxy...

journal_title：Environmental toxicology

authors： Tarja N,Kirsti E,Marja L,Kari E

更新日期：2003-08-01 00:00:00

abstract：:Recent epidemiological studies have revealed significant positive associations between exposure to organochlorine (OC) pesticides and occurrence of the metabolic syndrome and there are a growing number of animal-based studies to support causality. However, the cellular mechanisms linking OC compound exposure and metab...

journal_title：Environmental toxicology

authors： Howell GE 3rd,McDevitt E,Henein L,Mulligan C,Young D

更新日期：2018-09-01 00:00:00

abstract：:The correlation between the content of three microcystins (types LR, RR and YR) and the cell cycle of an axenic strain of Microcystis viridis, NIES-102, was investigated under conditions of high (16 mg L(-1)) and low (1.0 mg L(-1)) nitrate (NO(3)-N) concentrations. Each phase of the cell cycle was identified using a f...

journal_title：Environmental toxicology

authors： Kameyama K,Sugiura N,Inamori Y,Maekawa T

更新日期：2004-02-01 00:00:00

abstract：:Structure-activity relationships for oestrogenicity were developed based on 120 aromatic chemicals evaluated in the Saccharomyces cerevisiae-based Lac-Z reporter assay. Relative gene activation was compared to 17 beta-estradiol and varied over eight orders of magnitude. Analysis of the data compared to 17 beta-estradi...

journal_title：Environmental toxicology

authors： Schultz TW,Sinks GD,Cronin MT

更新日期：2002-02-01 00:00:00

abstract：:Nickel nanoparticles (Ni NPs) are associated with reproductive toxicity. However, the mechanisms of reproductive toxicity are unclear. Our goal was to explore further reproductive toxicity induced by nickel nanoparticle and mechanisms involved in this process, including the role of oxidative stress and apoptosis. Acco...

journal_title：Environmental toxicology

authors： Kong L,Gao X,Zhu J,Cheng K,Tang M

更新日期：2016-11-01 00:00:00

abstract：:Microcystins (MCs), as the most dominant bloom-forming strains in eutrophic surface water, can induce hepatotoxicity by oxidative stress. Alpha-lipoic acid (α-LA) is a super antioxidant that can induce the synthesis of antioxidants, such as glutathione (GSH), by nuclear factor erythroid 2-related factor 2 (Nrf2). Howe...

journal_title：Environmental toxicology

authors： Gu L,Li S,Bai J,Zhang Q,Han Z

更新日期：2020-07-01 00:00:00

abstract：:The aim of this study was to examine the occurrence of endocrine disruption close to sewage treatment plant effluent discharges along the Finnish Baltic Sea coast using a set of reproductive biomarkers present in adult three-spined stickleback (Gasterosteus aculeatus). Possible variation and sensitivity of the biomark...

journal_title：Environmental toxicology

authors： Björkblom C,Mustamäki N,Olsson PE,Katsiadaki I,Wiklund T

更新日期：2013-04-01 00:00:00

abstract：:In recent years cyanobacteria blooms have become a severe problem in Taihu Lake, a large shallow eutrophic lake in China. Microcystins produced by certain genera of cyanobacteria can affect public health in this area because of their acute and chronic toxic effects. In this study, samples of cyanobacteria were collect...

journal_title：Environmental toxicology

authors： Wu JY,Xu QJ,Gao G,Shen JH

更新日期：2006-06-01 00:00:00

abstract：:The present study was designed to understand the oxidative stress potential of fenthion, an organophosphate (OP) pesticide and its involvement in glutathione metabolism modulated buthionine sulfoximine (BSO, 50 mg/kg) and N-acetylcysteine (NAC, 100 mg/kg) in the brain of fish, Oreochromis niloticus. A sublethal fenthi...

journal_title：Environmental toxicology

authors： Piner P,Sevgiler Y,Uner N

更新日期：2007-12-01 00:00:00

abstract：:The microbial assay for risk assessment (MARA) is an innovative system based on an array of 11 different microbial species freeze-dried in a 96-well micro-titer plate. Developed for testing the toxicity of chemicals, mixtures, and environmental samples, the assay employs species of a taxonomically diverse range. In ad...

journal_title：Environmental toxicology

authors： Wadhia K

更新日期：2008-10-01 00:00:00

abstract：:The synergic allergic inflammatory effects of particulate matter (PM) 2.5 and human albumin were investigated in NC/Nga mice, which are hypersensitive to mite allergens. PM2.5 or PM2.5 plus human albumin with aluminum oxide was injected twice intraperitoneally for sensitization. After 7 days, PM2.5 or PM2.5 plus human...

journal_title：Environmental toxicology

authors： Nagaoka K,Ogino K,Ogino N,Ito T,Takemoto K,Ogino S,Seki Y,Hamada H,Fujikura Y

更新日期：2019-07-01 00:00:00

abstract：:There is increasing worldwide interest in developing of markers for tumor diagnosis and identification of individuals who are at high cancer risk. Cancer, like other diseases accompanied by metabolic disorders, causes characteristic effects on cell turnover rate, activity of modifying enzymes, and RNA/DNA modification...

journal_title：Environmental toxicology

authors： Seidel A,Seidel P,Manuwald O,Herbarth O

更新日期：2015-07-08 00:00:00

abstract：:Microcystin-LR (MC-LR) is the most commonly encountered of the toxic cyclic peptide hepatotoxins occurring in China. It is a model compound for toxicological studies. In this study, the toxicity of MC-LR (50 and 500 micrograms/L) on isolated carp hepatocytes was determined and the ultrastructural alterations of cells ...

journal_title：Environmental toxicology

authors： Li X,Liu Y,Song L

更新日期：2001-01-01 00:00:00

abstract：:Lake Elphinstone is a tropical inland water body in the far north of the Fitzroy Catchment in Central Queensland, Australia, and has experienced recurrent toxic cyanoprokaryote blooms since 1997. This article reports on an examination of the environmental conditions of the lake and the concurrent cyanoprokaryote speci...

journal_title：Environmental toxicology

authors： White SH,Fabbro LD,Duivenvoorden LJ

更新日期：2003-12-01 00:00:00

abstract：:Human exposure to bisphenol A (BPA) could favor obesity and related metabolic disorders such as hepatic steatosis. Investigations in rodents have shown that these deleterious effects are observed not only when BPA is administered during the adult life but also with different protocols of perinatal exposure. Whether pe...

journal_title：Environmental toxicology

authors： Bucher S,Jalili P,Le Guillou D,Begriche K,Rondel K,Martinais S,Zalko D,Corlu A,Robin MA,Fromenty B

更新日期：2017-03-01 00:00:00

abstract：:New reports indicate that the toxic alkaloid cylindrospermopsin occurs in cyanobacteria in Israel, Florida, South America, and Australia in drinking water sources. This toxin is now recognised as a potential threat to human health. Furthermore, we have recently demonstrated the mutagenicity of cylindrospermopsin in vi...

journal_title：Environmental toxicology

authors： Falconer IR,Humpage AR

更新日期：2001-01-01 00:00:00

abstract：:Toxicity of lead on male reproductive functions has raised wide public concern as environmental lead contamination remains common worldwide. Conflicting and controversial data are available regarding effects of lead on male fertility. More importantly, our knowledge on effects of lead on sperm DNA integrity is signifi...

journal_title：Environmental toxicology

authors： Li C,Zhao K,Zhang H,Liu L,Xiong F,Wang K,Chen B

更新日期：2018-05-01 00:00:00

abstract：:An important disturbance of anthropogenic origin frequently occurring in freshwater ecosystems is a rise in the concentration of heavy metals in solution, among which copper stands out due to its known toxicity. However, the study of the chemical behavior of copper in solution is highly dependent on pH. In this study,...

journal_title：Environmental toxicology

authors： Gagneten AM,Vila I

更新日期：2001-10-01 00:00:00

abstract：:We cloned the full-length cDNA sequence of xenobiotic metabolizing cytochrome P4501A (CYP1A) gene from the yellow catfish (Pelteobagrus fulvidraco, Siluriformes, Bagridae). P. fulvidraco is a commercially important fish generally distributed in Southeast Asian countries and Korea. This is the first report of any xenob...

journal_title：Environmental toxicology

authors： Kim JH,Hwang DS,Son KH,Raisuddin S,Ki JS,Lee JS,Han KN

更新日期：2008-06-01 00:00:00

abstract：:Oral cancer is one of the cancer-related diseases in human populations and its incidence rates are rising worldwide. Fisetin, a flavonoid from natural products, has been shown to exhibit anticancer activities in many human cancer cell lines but the molecular mechanism of fisetin-induced apoptosis in human oral cancer ...

journal_title：Environmental toxicology

authors： Su CH,Kuo CL,Lu KW,Yu FS,Ma YS,Yang JL,Chu YL,Chueh FS,Liu KC,Chung JG

更新日期：2017-06-01 00:00:00

abstract：:Some species of the genera Anabaena can produce various kinds of cyanotoxins, which may pose risks to environment and human health. Anabaena has frequently been observed in eutrophic freshwater of China in recent years, but its toxicity has been reported only in a few studies. In the present study, the toxicity of an ...

journal_title：Environmental toxicology

authors： Pan X,Chang F,Liu Y,Li D,Xu A,Shen Y,Huang Z

更新日期：2009-02-01 00:00:00

abstract：:Wood dusts, as a group, are categorized as known human carcinogens, but the risks of exposure to specific types of wood dusts and the carcinogenic chemicals they contain are not well studied. Aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that is linked to the carcinogenic action of specifi...

journal_title：Environmental toxicology

authors： Wilson MJ,Sabbioni G,Rando R,Miller CA 3rd

更新日期：2015-12-01 00:00:00

abstract：:Butein is a flavonoid isolated from various medicinal plants. It is known to have different biological activities including anti-inflammation, anti-adipogenesis, and anti-angiogenesis. In the study, we demonstrated the anti-proliferative effect of butein in human osteosarcoma U-2 OS cells. Our data showed that butein ...

journal_title：Environmental toxicology

authors： Hsu YK,Chen HY,Wu CC,Huang YC,Hsieh CP,Su PF,Huang YF

更新日期：2020-12-16 00:00:00

abstract：:Contamination of the urban aquatic environment with chemical and biological substances could have a long-term impact on human health because these substances threaten the integrity of the urban ecosystem and the availability of high-quality water for recreation and consumption. In light of this, the aim of the present...

journal_title：Environmental toxicology

authors： Wichmann G,Daegelmann C,Herbarth O,Strauch G,Schirmer K,Wöstemeyer J,Lehmann I

更新日期：2004-12-01 00:00:00

abstract：:Petroleum products-petrol, kerosene, and diesel-composed of volatile organic constituents contribute to air pollution. Exposure of gas station attendants (GSAs) to petroleum products fumes (PPFs) may account for occupation-related predisposition to respiratory toxicity and disease pathogenesis. We simulated GSA exposu...

journal_title：Environmental toxicology

authors： Owumi SE,Elebiyo TC,Oladimeji BN

更新日期：2020-09-07 00:00:00